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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50397469   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50397469
PNG
(CHEMBL2170841)
Show SMILES CC(C)Oc1cccc(c1)S(=O)(=O)Nc1ccc(cc1)N1CCN(CC1)c1cccc(c1)-c1c(C(=O)NCCCN2CCN(C)CC2)c(C)n(C)c1-c1ccc(Cl)cc1
Show InChI InChI=1S/C46H56ClN7O4S/c1-33(2)58-41-11-7-12-42(32-41)59(56,57)49-38-17-19-39(20-18-38)53-27-29-54(30-28-53)40-10-6-9-36(31-40)44-43(34(3)51(5)45(44)35-13-15-37(47)16-14-35)46(55)48-21-8-22-52-25-23-50(4)24-26-52/h6-7,9-20,31-33,49H,8,21-30H2,1-5H3,(H,48,55)
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Article
PubMed
 522n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to N-terminal 6xHis-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assay

J Med Chem 55: 8502-14 (2012)


Article DOI: 10.1021/jm3010306
BindingDB Entry DOI: 10.7270/Q2V69KQ9
More data for this
Ligand-Target Pair