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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50515614   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50515614
PNG
(CHEMBL4453195)
Show SMILES CC(C)(C)NC(=O)C(N(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)C=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O
Show InChI InChI=1S/C30H28Cl3N3O5/c1-30(2,3)35-28(38)27(25-20-12-9-18(31)13-24(20)34-26(25)29(39)40)36(16-37)14-17-7-10-19(11-8-17)41-15-21-22(32)5-4-6-23(21)33/h4-13,16,27,34H,14-15H2,1-3H3,(H,35,38)(H,39,40)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
 4.67E+3n/an/an/an/an/an/an/an/a



University of Groningen

Curated by ChEMBL


Assay Description
Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...

Eur J Med Chem 182: (2019)


Article DOI: 10.1016/j.ejmech.2019.111588
BindingDB Entry DOI: 10.7270/Q25H7KM3
More data for this
Ligand-Target Pair