Found 3 hits of ki for UniProtKB: P11799 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Myosin light chain kinase, smooth muscle
(Gallus gallus (chicken)) | BDBM15211
(CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[...)Show SMILES Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 Show InChI InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| 2.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biochemistry
Curated by ChEMBL
| Assay Description Inhibitory constant against MLCK |
J Biol Chem 271: 26157-64 (1996)
BindingDB Entry DOI: 10.7270/Q2BR8T3M |
More data for this Ligand-Target Pair | |
Myosin light chain kinase, smooth muscle
(Gallus gallus (chicken)) | BDBM15210
(CHEMBL148333 | H-8 | Lopac-M-9656 | N-(2-methylami...)Show InChI InChI=1S/C12H15N3O2S/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12/h2-6,9,13,15H,7-8H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biochemistry
Curated by ChEMBL
| Assay Description Inhibitory constant against MLCK |
J Biol Chem 271: 26157-64 (1996)
BindingDB Entry DOI: 10.7270/Q2BR8T3M |
More data for this Ligand-Target Pair | |
Myosin light chain kinase, smooth muscle
(Gallus gallus (chicken)) | BDBM50366348
(CHEMBL1233654)Show InChI InChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Similars
| PubMed
| 9.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biochemistry
Curated by ChEMBL
| Assay Description Inhibitory constant against MLCK |
J Biol Chem 271: 26157-64 (1996)
BindingDB Entry DOI: 10.7270/Q2BR8T3M |
More data for this Ligand-Target Pair | |