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Compile Data Set for Download or QSAR

Found 3 hits of kd for UniProtKB: Q9UBU7   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A


(Homo sapiens (Human))
BDBM50253706
PNG
(CHEMBL4083927)
Show SMILES Cc1n[nH]cc1-c1cc2nc(CN3CCCC3)[nH]c(=O)c2s1
Show InChI InChI=1S/C15H17N5OS/c1-9-10(7-16-19-9)12-6-11-14(22-12)15(21)18-13(17-11)8-20-4-2-3-5-20/h6-7H,2-5,8H2,1H3,(H,16,19)(H,17,18,21)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0.541n/an/an/an/an/a



Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...


Bioorg Med Chem 25: 3658-3670 (2017)


Article DOI: 10.1016/j.bmc.2017.04.044
BindingDB Entry DOI: 10.7270/Q26H4KTZ
More data for this
Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A


(Homo sapiens (Human))
BDBM50253762
PNG
(CHEMBL4098392)
Show SMILES O=c1[nH]c(CN2CCCC2)nc2cc(sc12)-c1cn[nH]c1
Show InChI InChI=1S/C14H15N5OS/c20-14-13-10(5-11(21-13)9-6-15-16-7-9)17-12(18-14)8-19-3-1-2-4-19/h5-7H,1-4,8H2,(H,15,16)(H,17,18,20)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.30n/an/an/an/an/a



Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...


Bioorg Med Chem 25: 3658-3670 (2017)


Article DOI: 10.1016/j.bmc.2017.04.044
BindingDB Entry DOI: 10.7270/Q26H4KTZ
More data for this
Ligand-Target Pair
Cell division cycle 7-related protein kinase/Protein DBF4 homolog A


(Homo sapiens (Human))
BDBM50253675
PNG
(CHEMBL4080367)
Show SMILES O=c1[nH]c(CN2CCCC2)nc2cc(sc12)-c1ccncc1
Show InChI InChI=1S/C16H16N4OS/c21-16-15-12(9-13(22-15)11-3-5-17-6-4-11)18-14(19-16)10-20-7-1-2-8-20/h3-6,9H,1-2,7-8,10H2,(H,18,19,21)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 2.80n/an/an/an/an/a



Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovir...


Bioorg Med Chem 25: 3658-3670 (2017)


Article DOI: 10.1016/j.bmc.2017.04.044
BindingDB Entry DOI: 10.7270/Q26H4KTZ
More data for this
Ligand-Target Pair