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Compile Data Set for Download or QSAR

Found 98 hits of kd for UniProtKB: P41182   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536505
PNG
((S)-7-(1-(2-((3-chloro- 6-(2,4-dimethylpipera- zin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 0.530n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536511
PNG
((S)-7-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- pipe...)
Show SMILES C[C@H]1CNCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 0.700n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536508
PNG
(7-(1-(2-((3-chloro-6- ((S)-2,4-dimethyl- piperazin...)
Show SMILES CC1Cc2nc3n(CC(=O)Nc4cc(nc(F)c4Cl)N4CCN(C)C[C@@H]4C)cc(-c4cc(C(N)=O)c(O)c5OCOc45)c3c(=O)n2C1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 0.770n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536507
PNG
((S)-7-(1-(2-((3-chloro- 6-(4-ethyl-2-methyl- piper...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 0.810n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536513
PNG
((S)-7-(1-(2-((3-chloro- 6-(2,4-dimethylpipera- zin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CC(C)(C)Cn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 0.870n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536517
PNG
((S)-7-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- pipe...)
Show SMILES C[C@H]1CNCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CC(C)(C)Cn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 0.960n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536519
PNG
(7-(1-(2-((3-chloro-2- fluoro-6-((2R,6S)-2,4,6- tri...)
Show SMILES C[C@H]1CN(C)C[C@@H](C)N1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 0.960n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536515
PNG
((S)-7-(1-(2-((3-chloro- 6-(2,4-dimethylpipera- zin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2COCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.33n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536510
PNG
(7-(1-(2-((3-chloro-6- ((S)-4-ethyl-2-methyl- piper...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CC(C)Cn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.36n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536498
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(4-(2- methoxye...)
Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.42n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536476
PNG
((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethyl- piperazin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.5n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536502
PNG
((S)-5-(1-(2-((3-chloro- 6-(4-ethyl-2-methyl- piper...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.55n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536506
PNG
((S)-7-(1-(2-((5-chloro- 2-(3-methylmorpholino) pyr...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c4OCOc34)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.61n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536514
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- pipe...)
Show SMILES C[C@H]1CNCCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 1.79n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536499
PNG
(5-(1-(2-((3-chloro-6- ((S)-2,4-dimethyl- piperazin...)
Show SMILES CC1Cc2nc3n(CC(=O)Nc4cc(nc(F)c4Cl)N4CCN(C)C[C@@H]4C)cc(-c4cc(F)c(O)c(c4)C(N)=O)c3c(=O)n2C1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 2.03n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536509
PNG
(7-(1-(2-((5-chloro-2- ((S)-3-methylmorpho- lino)py...)
Show SMILES CC1Cc2nc3n(CC(=O)Nc4cc(ncc4Cl)N4CCOC[C@@H]4C)cc(-c4cc(C(N)=O)c(O)c5OCOc45)c3c(=O)n2C1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 2.14n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536500
PNG
((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethyl- piperazin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CC(C)(C)Cn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 2.79n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536497
PNG
(5-(1-(2-((3-chloro-2- fluoro-6-(pyrrolidin-1- yl)p...)
Show SMILES NC(=O)c1cc(cc(F)c1O)-c1cn(CC(=O)Nc2cc(nc(F)c2Cl)N2CCCC2)c2nc3CCCn3c(=O)c12
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 3.02n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536467
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(4-(3- hydroxy-...)
Show SMILES C[C@H]1CN(CC(CO)CO)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 3.13n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536496
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-2-fluoro-6- (4-(2...)
Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 3.70n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536482
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylp...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 3.71n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536501
PNG
(5-(1-(2-((3-chloro-6- (dimethylamino)-2- fluoropyr...)
Show SMILES CN(C)c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 3.83n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536441
PNG
((S)-5-(1-(2-((3-chloro-2- fluoro-6-(2-methyl-4- (o...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1)C1COC1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 3.96n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536503
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-6-(4-ethyl- 2-met...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 4.13n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536423
PNG
((S)-3-chloro-5-(1-(2-((5- chloro-2-(3-methyl- morp...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 4.48n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536429
PNG
((S)-3-chloro-5-(1-(2- ((5-chloro-2-(2,4- dimethylp...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 5.27n/an/an/an/an/a


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This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536446
PNG
((S)-5-(1-(2-((3-chloro-2- fluoro-6-(4-(2- methoxye...)
Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536474
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- pipe...)
Show SMILES C[C@H]1CNCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536422
PNG
((S)-5-(1-(2-((3-chloro-6- (2,4-dimethylpiperazin- ...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 5.85n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536486
PNG
(3-chloro-5-(1-(2-((3- chloro-6-((S)-2,4- dimethylp...)
Show SMILES CC1Cc2nc3n(CC(=O)Nc4cc(nc(F)c4Cl)N4CCN(C)C[C@@H]4C)cc(-c4cc(Cl)c(O)c(c4)C(N)=O)c3c(=O)n2C1 |r|
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n/an/an/a 6.28n/an/an/an/an/a


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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536488
PNG
((S)-N-(3-chloro-6- (2,4-dimethyl- piperazin-1-yl)-...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C#N)c(O)c4OCOc34)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536483
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-2-fluoro- 6-(3-me...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536455
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- 4-(o...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2COCCn2c3=O)c(Cl)c(F)n1)C1COC1 |r|
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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536444
PNG
((S)-5-(1-(2-((3-chloro-6- (4-ethyl-2-methyl- piper...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 7.97n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536484
PNG
(5-(1-(2-((3-chloro-6- ((S)-2,4-dimethyl- piperazin...)
Show SMILES CC1Cc2nc3n(CC(=O)Nc4cc(nc(F)c4Cl)N4CCN(C)C[C@@H]4C)cc(-c4cc(C(N)=O)c(O)c(F)c4F)c3c(=O)n2C1 |r|
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n/an/an/a 10.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536454
PNG
((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethylpiperazin- ...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2COCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 11n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536478
PNG
((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethyl- piperazin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CC(C)(C)Cn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 11.2n/an/an/an/an/a


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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536504
PNG
(5-(1-(2-((3-chloro-2- fluoro-6-((2S,6S)-2,4,6- tri...)
Show SMILES C[C@H]1CN(C)C[C@H](C)N1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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UniProtKB/SwissProt

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n/an/an/a 11.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536426
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(3-methyl- morp...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 11.7n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536443
PNG
(5-(1-(2-((3-chloro-6- (dimethylamino)-2- fluoropyr...)
Show SMILES CN(C)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1
PDB

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n/an/an/a 11.8n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536518
PNG
(5-(1-(2-((3-chloro-2- fluoro-6-((2R,6S)-2,4,6- tri...)
Show SMILES C[C@H]1CN(C)C[C@@H](C)N1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 11.9n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536445
PNG
((S)-5-(1-(2-((3-chloro-6- (4-(cyclopropylmethyl)- ...)
Show SMILES C[C@H]1CN(CC2CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 12.3n/an/an/an/an/a


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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536481
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylp...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CC(C)(C)Cn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 13.4n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536469
PNG
((S)-5-(1-(2-((3-chloro- 6-(4-(2,2-difluoroethyl)- ...)
Show SMILES C[C@H]1CN(CC(F)F)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 13.7n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536458
PNG
(5-(1-(2-((3-chloro-2- fluoro-6-((S)-4-((S)-2- meth...)
Show SMILES CO[C@@H](C)CN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 14.4n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536495
PNG
(3-chloro-5-(1-(2-((3- chloro-2-fluoro-6- (pyrrolid...)
Show SMILES NC(=O)c1cc(cc(Cl)c1O)-c1cn(CC(=O)Nc2cc(nc(F)c2Cl)N2CCCC2)c2nc3CCCn3c(=O)c12
PDB

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n/an/an/a 14.8n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536487
PNG
(3-chloro-5-(1-(2-((3- chloro-2-fluoro-6- ((S)-3-me...)
Show SMILES CC1Cc2nc3n(CC(=O)Nc4cc(nc(F)c4Cl)N4CCOC[C@@H]4C)cc(-c4cc(Cl)c(O)c(c4)C(N)=O)c3c(=O)n2C1 |r|
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n/an/an/a 15.9n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536428
PNG
((S)-5-(1-(2-((5-chloro- 2-(2-methyl-4-(oxetan- 3-y...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1)C1COC1 |r|
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n/an/an/a 17.6n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536425
PNG
((S)-5-(1-(2-((5-chloro-2- (2,4-dimethylpiperazin-1...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
PDB

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n/an/an/a 23.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536457
PNG
(5-(1-(2-((5-chloro-2- (4-methylpiperazin-1- yl)pyr...)
Show SMILES CN1CCN(CC1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1
PDB

UniProtKB/SwissProt

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n/an/an/a 23.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
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