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Compile Data Set for Download or QSAR

Found 646 hits of kd for UniProtKB: Q16531   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631088
PNG
((1S)-N-(2,6-Dioxopiperidin-3-yl)-1,2,3,4-tetrahydr...)
Show SMILES O=C(NC1CCC(=O)NC1=O)[C@H]1CCCc2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627126
PNG
(3-Methoxy-N-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol...)
Show SMILES COc1cnccc1C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631094
PNG
((S)-N-(2,6-Dioxopiperidin-3-yl)benzofuran-3-carbox...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)c1coc2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631095
PNG
((N-((R)-2,6-Dioxopiperidin-3-yl)-6,7-dihydro-5H-cy...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)C1CCc2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631102
PNG
((S)-N-(2,6-Dioxopiperidin-3-yl)-2,3-dihydro-1H-pyr...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)N1CCc2cccnc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631105
PNG
((4S)-N-[(3S)-2,6-Dioxopiperidin-3-yl]-1,2,3,4-tetr...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)[C@H]1CCNc2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631110
PNG
(N-[(3S)-2,6-Dioxo-3-piperidyl]-1,2,3,4-tetrahydroq...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)C1CCNc2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631116
PNG
((4S)-N-[(3R)-2,6-Dioxopiperidin-3-yl]-1,2,3,4-tetr...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)[C@H]1CCNc2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631120
PNG
((S)-N-(2,6-Dioxopiperidin-3-yl)pyrazolo[1,5-a]pyri...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)c1cnn2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631121
PNG
((R)-N-(2,6-Dioxopiperidin-3-yl)pyrazolo[1,5-a]pyri...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)c1cnn2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631122
PNG
((R)-N-(2,6-Dioxopiperidin-3-yl)-1H-indazole-3-carb...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)c1n[nH]c2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631127
PNG
((S)-N-(2,6-Dioxopiperidin-3-yl)imidazo[1,2-a]pyrid...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)c1cnc2ccccn12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631128
PNG
((R)-N-(2,6-Dioxopiperidin-3-yl)imidazo[1,2-a]pyrid...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)c1cnc2ccccn12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627006
PNG
(5-(2-(Quinolin-4-yl)-1H-imidazol-1-yl)-1H-benzo[d]...)
Show SMILES O=c1[nH]c2ccc(cc2[nH]1)-n1ccnc1-c1ccnc2ccccc12
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627018
PNG
(5-(Indoline-1-carbonyl)-1H-benzo[d]imidazol-2(3H)-...)
Show SMILES O=C(N1CCc2ccccc12)c1ccc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627021
PNG
(1-Methyl-2-oxo-N-phenyl-3H-imidazo[4,5-b]pyridine-...)
Show SMILES Cn1c2cc(cnc2[nH]c1=O)C(=O)Nc1ccccc1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627024
PNG
(2-Isopropyl-N-methyl-2′-oxo-2′,3′...)
Show SMILES CNC(=O)c1ccc2nc(C(C)C)n(-c3ccc4[nH]c(=O)[nH]c4c3)c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627038
PNG
(1-Methyl-5-phenyl-3H-imidazo[4,5-b]pyridin-2-one |...)
Show SMILES Cn1c2ccc(nc2[nH]c1=O)-c1ccccc1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627049
PNG
(6-(Indoline-1-carbonyl)-1,3-dihydro-2H-imidazo[4,5...)
Show SMILES O=C(N1CCc2ccccc12)c1cnc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627056
PNG
(5-(4-Acetylpiperazin-1-yl)-1,3-dihydro-2H-benzo[d]...)
Show SMILES CC(=O)N1CCN(CC1)c1ccc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627064
PNG
(2-(4-Aminophenyl)-N-(2-oxo-2,3-dihydro-1H-benzo[d]...)
Show SMILES Nc1ccc(CC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627088
PNG
(1-Benzyl-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Show SMILES O=C(NCc1ccccc1)Nc1ccc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627100
PNG
(2-(4-(N-Methylsulfamoyl)phenyl)-N-(2-oxo-2,3-dihyd...)
Show SMILES CNS(=O)(=O)c1ccc(CC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631092
PNG
(N-((S)-2,6-Dioxopiperidin-3-yl)-6,7-dihydro-5H-cyc...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)C1CCc2ncccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631082
PNG
(N-(2,6-Dioxopiperidin-3-yl)indoline-1-carboxamide ...)
Show SMILES O=C(NC1CCC(=O)NC1=O)N1CCc2ccccc12
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631085
PNG
(N-(2,6-dioxo-3-piperidyl)benzofuran-3-carboxamide ...)
Show SMILES O=C(NC1CCC(=O)NC1=O)c1coc2ccccc12
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM600503
PNG
(US11623929, Example 5 | methyl 6-(2,4-dioxo-1,3,7-...)
Show SMILES COC(=O)c1ccc(nc1)N1CCC2(C1)NC(=O)NC2=O
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BindingDB Entry DOI: 10.7270/Q2NG4VM8
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627050
PNG
(N-(1-Acetylpiperidin-4-yl)-2-oxo-2,3-dihydro-1H-im...)
Show SMILES CC(=O)N1CCC(CC1)NC(=O)c1cnc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627068
PNG
(4-Acetamido-N-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...)
Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631126
PNG
((R)-N-(2,6-Dioxopiperidin-3-yl)indolizine-3-carbox...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)c1ccc2ccccn12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631089
PNG
(N-(2,6-Dioxopiperidin-3-yl)-N-methyl-1H-indole-3-c...)
Show SMILES CN(C1CCC(=O)NC1=O)C(=O)c1c[nH]c2ccccc12
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631093
PNG
(N-((R)-2,6-Dioxopiperidin-3-yl)-6,7-dihydro-5H-cyc...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)C1CCc2ncccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631100
PNG
((S)-N-((S)-2,6-Dioxopiperidin-3-yl)-1,2,3,4-tetrah...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)[C@H]1CCCc2ccccc12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631124
PNG
((R)-N-(2,6-Dioxopiperidin-3-yl)imidazo[1,5-a]pyrid...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)c1ncc2ccccn12 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631140
PNG
((R)-2-(3-Acetamidophenyl)-N-(2,6-dioxopiperidin-3-...)
Show SMILES CC(=O)Nc1cccc(CC(=O)N[C@@H]2CCC(=O)NC2=O)c1 |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631143
PNG
((R)-N-(2,6-Dioxopiperidin-3-yl)-2-(2-oxoindolin-5-...)
Show SMILES O=C(Cc1ccc2NC(=O)Cc2c1)N[C@@H]1CCC(=O)NC1=O |r|
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM600500
PNG
(7-((S)-1,2,3,4- tetrahydronaphthalene-1-carbonyl)-...)
Show SMILES O=C([C@H]1CCCc2ccccc12)N1CCC2(C1)NC(=O)NC2=O |r|
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BindingDB Entry DOI: 10.7270/Q2NG4VM8
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627076
PNG
(Methyl 1-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzi...)
Show SMILES COC(=O)c1nc2ccccc2n1-c1ccc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627077
PNG
(5-(Benzimidazol-1-yl)-1,3-dihydrobenzimidazol-2-on...)
Show SMILES O=c1[nH]c2ccc(cc2[nH]1)-n1cnc2ccccc12
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627078
PNG
(5-[2-(1-Hydroxyethyl)benzimidazol-1-yl]-1,3-dihydr...)
Show SMILES CC(O)c1nc2ccccc2n1-c1ccc2[nH]c(=O)[nH]c2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627079
PNG
(5-[2-[Hydroxy(phenyl)methyl]benzimidazol-1-yl]-1,3...)
Show SMILES OC(c1nc2ccccc2n1-c1ccc2[nH]c(=O)[nH]c2c1)c1ccccc1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627144
PNG
(N-(1-((2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)...)
Show SMILES CC(=O)Nc1ccc2N(Cc3ccc4[nH]c(=O)[nH]c4c3)CCc2c1
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Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627017
PNG
(N-(1-Acetylpiperidin-4-yl)-2-oxo-2,3-dihydro-1H-be...)
Show SMILES CC(=O)N1CCC(CC1)NC(=O)c1ccc2[nH]c(=O)[nH]c2c1
PDB

UniProtKB/SwissProt

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n/an/an/a 3n/an/an/an/an/a


TBA



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More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631087
PNG
((1R)-N-(2,6-Dioxopiperidin-3-yl)-1,2,3,4-tetrahydr...)
Show SMILES O=C(NC1CCC(=O)NC1=O)[C@@H]1CCCc2ccccc12 |r|
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Citation and Details
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631101
PNG
((S)-N-(2,6-Dioxopiperidin-3-yl)-3,4-dihydroquinoli...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)N1CCCc2ccccc12 |r|
PDB

UniProtKB/SwissProt

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Citation and Details
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631103
PNG
((S)-N-(2,6-Dioxopiperidin-3-yl)-3,4-dihydro-1,8-na...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)N1CCCc2cccnc12 |r|
PDB

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TBA



Citation and Details
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631118
PNG
((1R)-N-[(3R)-2,6-Dioxopiperidin-3-yl]-1,2,3,4-tetr...)
Show SMILES O=C(N[C@@H]1CCC(=O)NC1=O)[C@@H]1CCCc2ccccc12 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 4n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM631123
PNG
((S)-N-(2,6-Dioxopiperidin-3-yl)imidazo[1,5-a]pyrid...)
Show SMILES O=C(N[C@H]1CCC(=O)NC1=O)c1ncc2ccccn12 |r|
PDB

UniProtKB/SwissProt

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Citation and Details
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM600499
PNG
(7-benzoyl-1,3,7- triazaspiro[4.4]nonane-2,4-dione ...)
Show SMILES O=C(N1CCC2(C1)NC(=O)NC2=O)c1ccccc1
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Citation and Details

BindingDB Entry DOI: 10.7270/Q2NG4VM8
More data for this
Ligand-Target Pair
DNA damage-binding protein 1/Protein cereblon


(Homo sapiens (Human))
BDBM627073
PNG
(2-Isopropyl-N-methyl-1-(2-oxo-1,3-dihydroimidazo[4...)
Show SMILES CNC(=O)c1ccc2n(c(nc2c1)C(C)C)-c1cnc2[nH]c(=O)[nH]c2c1
PDB

UniProtKB/SwissProt

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TBA



Citation and Details
More data for this
Ligand-Target Pair
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