Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 2 [74-94] (Homo sapiens (Human)) | BDBM50452552 (CHEMBL4205876 | US11028051, Cmpd 52) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [74-94] (Homo sapiens (Human)) | BDBM50452556 (CHEMBL4210405 | US11028051, Cmpd 53) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [74-94] (Homo sapiens (Human)) | BDBM205429 ( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [74-94] (Homo sapiens (Human)) | BDBM50452557 (CHEMBL4206677 | US11028051, Cmpd 55) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [74-94] (Homo sapiens (Human)) | BDBM50452553 (CHEMBL4202664 | US11028051, Cmpd 54) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [74-94] (Homo sapiens (Human)) | BDBM50452554 (CHEMBL4207106 | US11028051, Cmpd 51) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 162 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [74-94] (Homo sapiens (Human)) | BDBM50452551 (CHEMBL4209110 | US11028051, Cmpd 50) | MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | n/a |
St. Jude Children''s Research Hospital US Patent | Assay Description Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over... | US Patent US11028051 (2021) BindingDB Entry DOI: 10.7270/Q2C250K7 | |||||||||||
More data for this Ligand-Target Pair |