Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Streptavidin (Streptomyces avidinii) | BDBM12 (5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]im...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0 | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Research and Development, LLC Curated by ChEMBL | Assay Description Binding affinity to Streptomyces avidinii streptavidin by NMR analysis | J Med Chem 57: 7819-37 (2014) Article DOI: 10.1021/jm500325k BindingDB Entry DOI: 10.7270/Q2JW8GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Streptavidin [37-163,Y46S,Y107S,R108K,E125D,R127K,E140N] (Streptomyces avidinii) | BDBM200813 (US9670255, Biocytin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.38 | n/a | n/a | n/a | n/a | n/a |
SAVID THERAPEUTICS INC. US Patent | Assay Description The amount of a ligand immobilized on a sensor chip was adjusted within the range of 1608 RU to 8042 RU, so as to suppress mass transport limitation.... | US Patent US9670255 (2017) BindingDB Entry DOI: 10.7270/Q298855H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Streptavidin (Streptomyces avidinii) | BDBM50045333 (CHEBI:90705 | SB-203580) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutical Research and Development, LLC Curated by ChEMBL | Assay Description Binding affinity to Streptomyces avidinii streptavidin by NMR analysis | J Med Chem 57: 7819-37 (2014) Article DOI: 10.1021/jm500325k BindingDB Entry DOI: 10.7270/Q2JW8GH3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Streptavidin [37-163,Y46S,N47D,S51D,Y107S,R108K,E125D,R127K,E140N] (Streptomyces avidinii) | BDBM200814 (US9670255, Compound 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a |
SAVID THERAPEUTICS INC. US Patent | Assay Description The amount of a ligand immobilized on a sensor chip was adjusted within the range of 1608 RU to 8042 RU, so as to suppress mass transport limitation.... | US Patent US9670255 (2017) BindingDB Entry DOI: 10.7270/Q298855H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Streptavidin [37-163,Y46S,N47D,S51D,Y107S,R108K,E125D,R127K,E140N] (Streptomyces avidinii) | BDBM200813 (US9670255, Biocytin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 348 | n/a | n/a | n/a | n/a | n/a |
SAVID THERAPEUTICS INC. US Patent | Assay Description The amount of a ligand immobilized on a sensor chip was adjusted within the range of 1608 RU to 8042 RU, so as to suppress mass transport limitation.... | US Patent US9670255 (2017) BindingDB Entry DOI: 10.7270/Q298855H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Streptavidin (Streptomyces avidinii) | BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.68E+5 | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Binding affinity to Streptomyces avidinii streptavidin using fluorescence spectral analysis method based double reciprocal plot analysis | Bioorg Med Chem Lett 22: 7052-5 (2012) Article DOI: 10.1016/j.bmcl.2012.09.088 BindingDB Entry DOI: 10.7270/Q2HX1GKC | |||||||||||
More data for this Ligand-Target Pair |