Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM5446![]() (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582536![]() (US11524945, Compound 8 (Csbl-2)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 922 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582532![]() (US11524945, Compound 4 (cmpd#4)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582529![]() (US11524945, Compound Erlotinib-4-methylphenyl anal...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582535![]() (US11524945, Compound 7 (cmpd-#7)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.45E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582530![]() (US11524945, Compound 1 (Csbl-1)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.77E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582528![]() (US11524945, Compound Gefitinib) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 4.51E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM50078209![]() (CHEMBL3414686) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a |
The Ohio State University Curated by ChEMBL | Assay Description Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopy | J Med Chem 58: 2290-8 (2015) Article DOI: 10.1021/jm501751b BindingDB Entry DOI: 10.7270/Q20V8FGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582533![]() (US11524945, Compound 1 New (cmpd#1new)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6.85E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582534![]() (US11524945, Compound 2 New (cmpd#2new)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM50078259![]() (CHEMBL3414669) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a |
The Ohio State University Curated by ChEMBL | Assay Description Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopy | J Med Chem 58: 2290-8 (2015) Article DOI: 10.1021/jm501751b BindingDB Entry DOI: 10.7270/Q20V8FGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM50078207![]() (CHEMBL3414688) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.31E+4 | n/a | n/a | n/a | n/a | n/a |
The Ohio State University Curated by ChEMBL | Assay Description Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopy | J Med Chem 58: 2290-8 (2015) Article DOI: 10.1021/jm501751b BindingDB Entry DOI: 10.7270/Q20V8FGX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin-linked protein kinase (Homo sapiens (Human)) | BDBM582531![]() (US11524945, Compound 3 (cmpd#3)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 4.96E+4 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob... | Citation and Details BindingDB Entry DOI: 10.7270/Q2542SFN | |||||||||||
More data for this Ligand-Target Pair |