Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F2Y] (Mycobacterium tuberculosis) | BDBM213240 (Cyclomarin A1 (CymA1)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 780 | n/a | n/a | n/a | 7.5 | 25 |
Novartis Institute for Tropical Diseases | Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 °C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ... | J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6 | |||||||||||
More data for this Ligand-Target Pair |