Compile Data Set for Download or QSAR

Found 40 hits Enz. Inhib. hit(s) with all data for entry = 10125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM136597 (US10005783, 14 | US10047097, 14 | US10774085, Exam...) Show SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F |r| Show InChI InChI=1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31)/t14-,18+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515065 (US11098046, Compound 1-8) Show SMILES C[C@@H]1CCc2ncc(F)cc2N2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515102 (US11098046, Compound 24-10) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@H]2[C@H]3[C@@H](CN2c2ccn4ncc(C(=O)N1)c4n2)C3(C)C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515100 (US11098046, Compound 23-3) Show SMILES C[C@H]1CNC(=O)c2cnn3ccc(nc23)N2C[C@H]3C[C@H]3[C@@H]2c2cc(F)cn1c2=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515098 (US11098046, Compound 22-6) Show SMILES C[C@H]1CNC(=O)c2cnn3ccc(nc23)N2C[C@H]3C[C@H]3[C@@H]2c2cc(F)cnc2O1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515096 (US11098046, Compound 21-4) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2C[C@H]3C[C@H]3[C@@H]2c2cc(F)cnc2C1=C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515094 (US11098046, Compound 20-5) Show SMILES Fc1cnc2CC[C@H](NC(=O)c3cnn4ccc(nc34)N3C[C@H]4C[C@H]4[C@@H]3c2c1)C1CC1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515092 (US11098046, Compound 19-5) Show SMILES Fc1cnc2CCC3(CC3)NC(=O)c3cnn4ccc(nc34)N3C[C@H]4C[C@H]4[C@@H]3c2c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515090 (US11098046, Compound 18-11) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@H]2[C@@H]3C[C@@H]3CN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515081 (US11098046, Compound 13-11) Show SMILES C[C@@H]1CCc2ncncc2[C@H]2CCCN2c2ccc3ncc(C(=O)N1)n3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515079 (US11098046, Compound 11-6) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2C1C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515077 (US11098046, Compound 11-4) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2C1=C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515075 (US11098046, Compound 10-5) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2\C=C/1 |r,c:30| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515074 (US11098046, Compound 9-7) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2CCC[C@@H]2c2cc(F)cnc2\C=C\1 |r,t:30| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515071 (US11098046, Compound 7-11) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@H]2CCCN2c2ccc3ncc(C(=O)N1)n3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515070 (US11098046, Compound 6-10) Show SMILES C[C@@H]1CCc2ncc(F)cc2N2CC3(CC3)CN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515068 (US11098046, Compound 4-3) Show SMILES C[C@@H]1CCOc2ncc(F)cc2N2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515066 (US11098046, Compound 1-17) Show SMILES C[C@@H]1CCc2ccccc2N2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515097 (US11098046, Compound 21-5) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2C[C@@H]3C[C@@H]3[C@H]2c2cc(F)cnc2C1=C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515076 (US11098046, Compound 10-6) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2CCC[C@H]2c2cc(F)cnc2\C=C/1 |r,c:30| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515073 (US11098046, Compound 8-8) Show SMILES CC1(C)CCc2ncc(F)cc2C2CCCN2c2ccn3ncc(NC1=O)c3n2 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515069 (US11098046, Compound 5-6) Show SMILES C[C@@H]1CCc2ncc(F)cc2N2CCC(=O)N2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515082 (US11098046, Compound 13-12) Show SMILES C[C@@H]1CCc2ncncc2[C@@H]2CCCN2c2ccc3ncc(C(=O)N1)n3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515080 (US11098046, Compound 12-12) Show SMILES C[C@@H]1CCc2cnc(F)cc2C2CCCN2c2ccc3ncc(C(=O)N1)n3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515101 (US11098046, Compound 23-4) Show SMILES C[C@H]1CNC(=O)c2cnn3ccc(nc23)N2C[C@@H]3C[C@@H]3[C@H]2c2cc(F)cn1c2=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515078 (US11098046, Compound 11-5) Show SMILES C[C@H]1NC(=O)c2cnn3ccc(nc23)N2CCC[C@H]2c2cc(F)cnc2C1=C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515093 (US11098046, Compound 19-6) Show SMILES Fc1cnc2CCC3(CC3)NC(=O)c3cnn4ccc(nc34)N3C[C@@H]4C[C@@H]4[C@H]3c2c1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515091 (US11098046, Compound 18-12) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@@H]2[C@H]3C[C@H]3CN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515072 (US11098046, Compound 7-12) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@@H]2CCCN2c2ccc3ncc(C(=O)N1)n3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515099 (US11098046, Compound 22-7) Show SMILES C[C@H]1CNC(=O)c2cnn3ccc(nc23)N2C[C@@H]3C[C@@H]3[C@H]2c2cc(F)cnc2O1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515089 (US11098046, Compound 17-13) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@@H]2[C@H]3[C@@H](CN2c2ccn4ncc(C(=O)N1)c4n2)C3(C)C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515088 (US11098046, Compound 17-12) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@H]2[C@@H]3[C@H](CN2c2ccn4ncc(C(=O)N1)c4n2)C3(C)C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515067 (US11098046, Compound 3-3) Show SMILES C[C@@H]1CCn2cc(F)cc(N3CCCN3c3ccn4ncc(C(=O)N1)c4n3)c2=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515087 (US11098046, Compound 16-11) Show SMILES C[C@@H]1CCc2ncc(F)cc2N2CCC[C@@H]2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515095 (US11098046, Compound 20-6) Show SMILES Fc1cnc2CC[C@H](NC(=O)c3cnn4ccc(nc34)N3C[C@@H]4C[C@@H]4[C@H]3c2c1)C1CC1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515086 (US11098046, Compound 16-10) Show SMILES C[C@@H]1CCc2ncc(F)cc2N2CCC[C@H]2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515085 (US11098046, Compound 15-10) Show SMILES C[C@@H]1CCn2nncc2[C@H]2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515084 (US11098046, Compound 14-7) Show SMILES C[C@@H]1CCn2cc(nn2)[C@@H]2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515103 (US11098046, Compound 24-11) Show SMILES C[C@@H]1CCc2ncc(F)cc2[C@@H]2[C@@H]3[C@H](CN2c2ccn4ncc(C(=O)N1)c4n2)C3(C)C |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM515083 (US11098046, Compound 14-6) Show SMILES C[C@@H]1CCn2cc(nn2)[C@H]2CCCN2c2ccn3ncc(C(=O)N1)c3n2 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HotSpot assay platform was used to measure kinase/inhibitor interactions as described in Anastassiadis et al., Nat Biotechnol. 29:1039-45, 2011. ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KK9FZ3
					More data for this Ligand-Target Pair