Compile Data Set for Download or QSAR

Found 264 hits Enz. Inhib. hit(s) with all data for entry = 10131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515603 (US11098063, Example 109) Show SMILES CCN(CC)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515513 ((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515512 ((3-Fluoro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515509 ((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-chloroph...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515584 (US11098063, Example 84) Show SMILES Brc1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC(C1)N2C(=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515579 (US11098063, Example 77 | US11098063, Example 78) Show SMILES COc1ccc(C)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(cc1)C(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515530 ((3-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 |TLB:9:11:13.14:17.35.16| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515512 ((3-Fluoro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515566 (US11098063, Example 64) Show SMILES CC(C)c1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC(C1)N2C(=O)c1ccccc1F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515528 ((3-Fluoro-6-methoxypyridin-2-yl)(7-{[2-(4-isopropy...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 |TLB:9:11:13.14.15:17.18.38| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515515 (US11098063, Example 51) Show SMILES CCc1ocnc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515511 ((5-Cyclopropyl-1,3-oxazol-4-yl)(5-{[2-(4-isopropyl...) Show SMILES CC(C)c1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC1CN2C(=O)c1ncoc1C1CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515552 (US11098063, Example 49) Show SMILES CC(C)c1ocnc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515526 ((7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...) Show SMILES CSc1cccc(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 |THB:8:10:12.13.14:17.35.16| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515556 (US11098063, Example 54) Show SMILES CC(C)c1nc(cs1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515522 (US11098063, Example 12) Show SMILES CC(C)(C)OC(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Br)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515583 (US11098063, Example 83) Show SMILES Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Br)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515619 (US11098063, Example 126) Show SMILES CCCOC(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515565 (US11098063, Example 63) Show SMILES COc1cccc(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515510 ((3-Chloro-6-methoxypyridin-2-yl)(5-{[2-(4-isopropy...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(cc1)C(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515521 (US11098063, Example 11) Show SMILES CC(C)(C)OC(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(Br)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515617 (US11098063, Example 124) Show SMILES CCOC(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515569 (US11098063, Example 67) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 |TLB:19:18:11:13.15.14| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515560 (US11098063, Example 58) Show SMILES FC(F)(F)c1nc(cs1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM515511 ((5-Cyclopropyl-1,3-oxazol-4-yl)(5-{[2-(4-isopropyl...) Show SMILES CC(C)c1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC1CN2C(=O)c1ncoc1C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515525 ((7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 |TLB:19:18:13.14.15:11| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515555 (US11098063, Example 53) Show SMILES Clc1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC(C1)N2C(=O)c1ncoc1C1CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM515509 ((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-chloroph...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515568 (US11098063, Example 66) Show SMILES COc1cccc(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 |TLB:18:17:10:12.14.13| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515511 ((5-Cyclopropyl-1,3-oxazol-4-yl)(5-{[2-(4-isopropyl...) Show SMILES CC(C)c1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC1CN2C(=O)c1ncoc1C1CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM515512 ((3-Fluoro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM515513 ((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-isopropy...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C(C)C)C2 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515581 (US11098063, Example 81) Show SMILES COc1ccc(F)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(Br)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM515515 (US11098063, Example 51) Show SMILES CCc1ocnc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515510 ((3-Chloro-6-methoxypyridin-2-yl)(5-{[2-(4-isopropy...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(cc1)C(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515551 (US11098063, Example 48) Show SMILES Cc1ocnc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515579 (US11098063, Example 77 | US11098063, Example 78) Show SMILES COc1ccc(C)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(cc1)C(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM515603 (US11098063, Example 109) Show SMILES CCN(CC)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515618 (US11098063, Example 125) Show SMILES Clc1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC(C1)N2C(=O)OC1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515536 (US11098063, Example 32) Show SMILES Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515573 (US11098063, Example 71 | US11098063, Example 72) Show SMILES COc1ccc(F)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(cc1)C(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515538 (US11098063, Example 34) Show SMILES Clc1ccc(cc1)-c1nc2ncccn2c1CN1CC2CCC(C1)N2C(=O)C1CCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM515510 ((3-Chloro-6-methoxypyridin-2-yl)(5-{[2-(4-isopropy...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1CC2CCC1CN2Cc1c(nc2ncccn12)-c1ccc(cc1)C(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 1: In Vitro Electrophysiological Analysis of the Human TASK-1 and TASK-3 Channels Via Two-Electrode Voltage Clamp Technique in Xenopus laevis O...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515509 ((3-Chloro-6-methoxypyridin-2-yl)(3-{[2-(4-chloroph...) Show SMILES COc1ccc(Cl)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515527 ((7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...) Show SMILES Clc1ccc(cc1)-c1nc2ncccn2c1CN1CC2COCC(C1)N2C(=O)C1CCCC1 |THB:16:17:20.21.22:25| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515523 ((7-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...) Show SMILES COc1cccc(n1)C(=O)N1C2COCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 |TLB:18:17:12.13.14:10| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515626 (US11098063, Example 135) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(cc1)C1CC1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515515 (US11098063, Example 51) Show SMILES CCc1ocnc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515582 (US11098063, Example 82) Show SMILES COc1ccc(F)c(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Br)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM515529 ((3-{[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-y...) Show SMILES COc1cccc(n1)C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)C2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2T43X7W
					More data for this Ligand-Target Pair

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