Compile Data Set for Download or QSAR

Found 100 hits Enz. Inhib. hit(s) with all data for entry = 10222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521018 (US11149020, Compound 10 (MW-167)) Show SMILES Fc1cnccc1-c1cc(nnc1-c1ccc2ccccc2c1)C1CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521021 (US11149020, Compound 13 (MW-107)) Show SMILES C1CC1Nc1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521019 (US11149020, Compound 11 (MW-122)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521025 (US11149020, Compound 16 (MW-200)) Show SMILES CNc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521045 (US11149020, Compound 36 (MW-164)) Show SMILES CC1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537600 (CHEMBL4129018 | US11149020, Compound 27 (MW-150)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C24H23N5/c1-28-12-14-29(15-13-28)23-17-22(19-8-10-25-11-9-19)24(27-26-23)21-7-6-18-4-2-3-5-20(18)16-21/h2-11,16-17H,12-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537599 (CHEMBL4648060 | US11149020, Compound 2 (MW-108)) Show SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C21H18N4/c1-25(2)20-14-19(16-9-11-22-12-10-16)21(24-23-20)18-8-7-15-5-3-4-6-17(15)13-18/h3-14H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521017 (US11149020, Compound 9 (MW-125)) Show SMILES C1CC1c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537598 (CHEMBL4646628 | US11149020, Compound 1 (MW-181)) Show SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI InChI=1S/C21H18N4/c1-25(2)20-14-19(16-10-12-22-13-11-16)21(24-23-20)18-9-5-7-15-6-3-4-8-17(15)18/h3-14H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	184	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521016 (US11149020, Compound 7 (MW-077)) Show SMILES C1CC1c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521024 (US11149020, Compound 15 (MW-156)) Show SMILES CNc1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521047 (N,N-dimethyl-5-(naphthalen-1-yl)-6-(pyridin-4-yl)p...) Show SMILES CN(C)c1cnc(-c2cccc3ccccc23)c(n1)-c1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	343	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537597 (CHEMBL4645737 | US11149020, Compound 6 (MW-105)) Show SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C17H16N4/c1-21(2)16-12-15(13-8-10-18-11-9-13)17(20-19-16)14-6-4-3-5-7-14/h3-12H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	657	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537606 (CHEMBL4647072 | US11149020, Compound 34 (MW-154)) Show SMILES C1CN(CCN1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C23H21N5/c1-2-4-19-15-20(6-5-17(19)3-1)23-21(18-7-9-24-10-8-18)16-22(26-27-23)28-13-11-25-12-14-28/h1-10,15-16,25H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521035 (US11149020, Compound 26 (MW-025)) Show SMILES CC(C)Nc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50537593 (CHEMBL4639555 | US11149020, Compound 3 (MW-066)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C20H21N5/c1-24-11-13-25(14-12-24)19-15-18(16-7-9-21-10-8-16)20(23-22-19)17-5-3-2-4-6-17/h2-10,15H,11-14H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521022 (US11149020, Compound 14 (MW-109)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2F)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521032 (US11149020, Compound 23 (MW-033)) Show SMILES CCN(CC)c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521034 (US11149020, Compound 25 (MW-031)) Show SMILES CC(C)Nc1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521025 (US11149020, Compound 16 (MW-200)) Show SMILES CNc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537608 (CHEMBL4639995 | US11149020, Compound 32 (MW-148)) Show SMILES C1CCN(C1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C23H20N4/c1-2-6-19-15-20(8-7-17(19)5-1)23-21(18-9-11-24-12-10-18)16-22(25-26-23)27-13-3-4-14-27/h1-2,5-12,15-16H,3-4,13-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521019 (US11149020, Compound 11 (MW-122)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521033 (US11149020, Compound 24 (MW-010)) Show SMILES CN(C)CCc1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521044 (US11149020, Compound 35 (MW-153)) Show SMILES C1CC1Nc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521020 (US11149020, Compound 12 (MW-124)) Show SMILES C1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537598 (CHEMBL4646628 | US11149020, Compound 1 (MW-181)) Show SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI InChI=1S/C21H18N4/c1-25(2)20-14-19(16-10-12-22-13-11-16)21(24-23-20)18-9-5-7-15-6-3-4-8-17(15)18/h3-14H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	215	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521045 (US11149020, Compound 36 (MW-164)) Show SMILES CC1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521046 (US11149020, Compound 37 (MW-149)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2F)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537599 (CHEMBL4648060 | US11149020, Compound 2 (MW-108)) Show SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C21H18N4/c1-25(2)20-14-19(16-9-11-22-12-10-16)21(24-23-20)18-8-7-15-5-3-4-6-17(15)13-18/h3-14H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537595 (CHEMBL4642101 | US11149020, Compound 4 (MW-177)) Show SMILES CCN(CC)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C19H20N4/c1-3-23(4-2)18-14-17(15-10-12-20-13-11-15)19(22-21-18)16-8-6-5-7-9-16/h5-14H,3-4H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537609 (CHEMBL4643246 | US11149020, Compound 31 (MW-146)) Show SMILES C1CN(C1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C22H18N4/c1-2-5-18-14-19(7-6-16(18)4-1)22-20(17-8-10-23-11-9-17)15-21(24-25-22)26-12-3-13-26/h1-2,4-11,14-15H,3,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521021 (US11149020, Compound 13 (MW-107)) Show SMILES C1CC1Nc1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537600 (CHEMBL4129018 | US11149020, Compound 27 (MW-150)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C24H23N5/c1-28-12-14-29(15-13-28)23-17-22(19-8-10-25-11-9-19)24(27-26-23)21-7-6-18-4-2-3-5-20(18)16-21/h2-11,16-17H,12-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50537596 (CHEMBL4648747 | US11149020, Compound 5 (MW-207)) Show SMILES CCCN(C)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C19H20N4/c1-3-13-23(2)18-14-17(15-9-11-20-12-10-15)19(22-21-18)16-7-5-4-6-8-16/h4-12,14H,3,13H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521024 (US11149020, Compound 15 (MW-156)) Show SMILES CNc1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	289	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521018 (US11149020, Compound 10 (MW-167)) Show SMILES Fc1cnccc1-c1cc(nnc1-c1ccc2ccccc2c1)C1CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	307	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50537595 (CHEMBL4642101 | US11149020, Compound 4 (MW-177)) Show SMILES CCN(CC)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C19H20N4/c1-3-23(4-2)18-14-17(15-10-12-20-13-11-15)19(22-21-18)16-8-6-5-7-9-16/h5-14H,3-4H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	369	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521031 (US11149020, Compound 22 (MW-066)) Show SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1ccc2[nH]ccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	369	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50537605 (CHEMBL4635980 | US11149020, Compound 28 (MW-118)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C22H22N6/c1-27-10-12-28(13-11-27)21-15-19(16-4-7-23-8-5-16)22(26-25-21)18-2-3-20-17(14-18)6-9-24-20/h2-9,14-15,24H,10-13H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537596 (CHEMBL4648747 | US11149020, Compound 5 (MW-207)) Show SMILES CCCN(C)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C19H20N4/c1-3-13-23(2)18-14-17(15-9-11-20-12-10-15)19(22-21-18)16-7-5-4-6-8-16/h4-12,14H,3,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521017 (US11149020, Compound 9 (MW-125)) Show SMILES C1CC1c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521016 (US11149020, Compound 7 (MW-077)) Show SMILES C1CC1c1cc(-c2ccncc2)c(nn1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	419	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521047 (N,N-dimethyl-5-(naphthalen-1-yl)-6-(pyridin-4-yl)p...) Show SMILES CN(C)c1cnc(-c2cccc3ccccc23)c(n1)-c1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	456	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521042 (US11149020, Compound 33 (MW-152)) Show SMILES C1CN(CCO1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537593 (CHEMBL4639555 | US11149020, Compound 3 (MW-066)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C20H21N5/c1-24-11-13-25(14-12-24)19-15-18(16-7-9-21-10-8-16)20(23-22-19)17-5-3-2-4-6-17/h2-10,15H,11-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537605 (CHEMBL4635980 | US11149020, Compound 28 (MW-118)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C22H22N6/c1-27-10-12-28(13-11-27)21-15-19(16-4-7-23-8-5-16)22(26-25-21)18-2-3-20-17(14-18)6-9-24-20/h2-9,14-15,24H,10-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	518	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521056 (US11149020, Compound 62 (MW-026)) Show SMILES CCN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521054 (US11149020, Compound 55 (MW-063)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1cccc2c(F)cccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	526	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50537597 (CHEMBL4645737 | US11149020, Compound 6 (MW-105)) Show SMILES CN(C)c1cc(-c2ccncc2)c(nn1)-c1ccccc1 Show InChI InChI=1S/C17H16N4/c1-21(2)16-12-15(13-8-10-18-11-9-13)17(20-19-16)14-6-4-3-5-7-14/h3-12H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	543	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521053 (US11149020, Compound 54 (MW-197)) Show SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1cccc2cc(F)ccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	669	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
					More data for this Ligand-Target Pair

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