Compile Data Set for Download or QSAR

Found 634 hits Enz. Inhib. hit(s) with all data for entry = 10294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385373 (US10287267, Compound 1083 | US10508099, Compound 1...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C34CC(CO)(C3)C4)cc2c1 Show InChI InChI=1S/C20H20N4O2/c1-24-8-16(7-22-24)13-2-3-14-6-21-17(5-15(14)4-13)23-18(26)20-9-19(10-20,11-20)12-25/h2-8,25H,9-12H2,1H3,(H,21,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM422353 (US10508099, Compound 1084 | US10556885, Compound 1...) Show SMILES COC(=O)[C@H]1CC[C@@H](CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 |r,wU:4.3,wD:7.10,(9.96,1.89,;8.62,1.14,;7.3,1.92,;7.32,3.46,;5.95,1.17,;5.85,-.38,;4.52,-1.15,;3.19,-.38,;3.19,1.15,;4.52,1.93,;1.85,-1.15,;1.85,-2.69,;.52,-.38,;-.82,-1.15,;-2.15,-.38,;-3.48,-1.15,;-4.82,-.38,;-6.15,-1.15,;-6.15,-2.69,;-4.82,-3.47,;-3.48,-2.69,;-2.15,-3.47,;-.82,-2.69,;-7.48,-.38,;-8.95,-.86,;-9.85,.38,;-8.95,1.63,;-9.72,2.96,;-7.48,1.15,)| Show InChI InChI=1S/C22H24N4O3/c1-26-13-19(12-24-26)16-7-8-17-11-23-20(10-18(17)9-16)25-21(27)14-3-5-15(6-4-14)22(28)29-2/h7-15H,3-6H2,1-2H3,(H,23,25,27)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385067 (US10287267, Compound 1085 | US10287267, Compound 7...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCNCC3)cc2c1 Show InChI InChI=1S/C19H21N5O/c1-24-12-17(11-22-24)14-2-3-15-10-21-18(9-16(15)8-14)23-19(25)13-4-6-20-7-5-13/h2-3,8-13,20H,4-7H2,1H3,(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385079 (US10287267, Compound 1086 | US10287267, Compound 1...) Show SMILES CC(C)CN1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H29N5O/c1-16(2)14-28-8-6-17(7-9-28)23(29)26-22-11-20-10-18(4-5-19(20)12-24-22)21-13-25-27(3)15-21/h4-5,10-13,15-17H,6-9,14H2,1-3H3,(H,24,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385079 (US10287267, Compound 1086 | US10287267, Compound 1...) Show SMILES CC(C)CN1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H29N5O/c1-16(2)14-28-8-6-17(7-9-28)23(29)26-22-11-20-10-18(4-5-19(20)12-24-22)21-13-25-27(3)15-21/h4-5,10-13,15-17H,6-9,14H2,1-3H3,(H,24,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385378 (US10287267, Compound 1088 | US10508099, Compound 1...) Show SMILES CN1CCN(CC23CC(C2)(C3)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C25H30N6O/c1-29-5-7-31(8-6-29)17-24-14-25(15-24,16-24)23(32)28-22-10-20-9-18(3-4-19(20)11-26-22)21-12-27-30(2)13-21/h3-4,9-13H,5-8,14-17H2,1-2H3,(H,26,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385379 (US10287267, Compound 1090 | US10508099, Compound 1...) Show SMILES CN1CCC(CC1)NC(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C20H24N6O/c1-25-7-5-18(6-8-25)23-20(27)24-19-10-16-9-14(3-4-15(16)11-21-19)17-12-22-26(2)13-17/h3-4,9-13,18H,5-8H2,1-2H3,(H2,21,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.90	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385380 (US10287267, Compound 1091 | US11174244, Compound 1...) Show SMILES CN1CCN(CC1)C(=O)[C@H]1CC[C@@H](CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 |r,wU:12.16,wD:9.9,(11.19,-1.16,;9.85,-.39,;8.52,-1.16,;7.19,-.39,;7.19,1.16,;8.52,1.93,;9.85,1.16,;5.85,1.93,;5.85,3.47,;4.52,1.16,;3.19,1.93,;1.85,1.16,;1.85,-.39,;3.19,-1.16,;4.52,-.39,;.52,-1.16,;.52,-2.7,;-.82,-.39,;-2.15,-1.16,;-3.48,-.39,;-4.82,-1.16,;-6.15,-.39,;-7.48,-1.16,;-7.48,-2.7,;-6.15,-3.47,;-4.82,-2.7,;-3.48,-3.47,;-2.15,-2.7,;-8.82,-.39,;-10.28,-.86,;-11.19,.38,;-10.28,1.63,;-11.05,2.96,;-8.82,1.15,)| Show InChI InChI=1S/C26H32N6O2/c1-30-9-11-32(12-10-30)26(34)19-5-3-18(4-6-19)25(33)29-24-14-22-13-20(7-8-21(22)15-27-24)23-16-28-31(2)17-23/h7-8,13-19H,3-6,9-12H2,1-2H3,(H,27,29,33)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385381 (US10287267, Compound 1092 | US10508099, Compound 1...) Show SMILES CC(C)CN1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1nnnn1C Show InChI InChI=1S/C21H27N7O/c1-14(2)13-28-8-6-15(7-9-28)21(29)23-19-11-18-10-16(4-5-17(18)12-22-19)20-24-25-26-27(20)3/h4-5,10-12,14-15H,6-9,13H2,1-3H3,(H,22,23,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	62.7	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM385128 (US10287267, Compound 284 | US10287267, Compound 30...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)CN3CCCC3)cc2c1 Show InChI InChI=1S/C19H21N5O/c1-23-12-17(11-21-23)14-4-5-15-10-20-18(9-16(15)8-14)22-19(25)13-24-6-2-3-7-24/h4-5,8-12H,2-3,6-7,13H2,1H3,(H,20,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	11.7	n/a	n/a	n/a	n/a
TBA					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385041 (US10287267, Compound 1 | US10508099, Compound 1 | ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CC3)cc2c1 Show InChI InChI=1S/C17H16N4O/c1-21-10-15(9-19-21)12-4-5-13-8-18-16(7-14(13)6-12)20-17(22)11-2-3-11/h4-11H,2-3H2,1H3,(H,18,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385042 (US10287267, Compound 3 | US10508099, Compound 3 | ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCC(F)(F)CC3)cc2c1 Show InChI InChI=1S/C20H20F2N4O/c1-26-12-17(11-24-26)14-2-3-15-10-23-18(9-16(15)8-14)25-19(27)13-4-6-20(21,22)7-5-13/h2-3,8-13H,4-7H2,1H3,(H,23,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM422047 (US10508099, Compound 4 | US10556885, Compound 4 | ...) Show SMILES CO[C@H]1CC[C@@H](CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 |r,wU:2.1,wD:5.8,(8.57,3.49,;8.57,1.95,;7.23,1.18,;7.19,-.38,;5.85,-1.15,;4.52,-.38,;4.52,1.15,;5.85,1.93,;3.19,-1.15,;3.19,-2.69,;1.85,-.38,;.52,-1.15,;-.82,-.38,;-2.15,-1.15,;-3.48,-.38,;-4.82,-1.15,;-4.82,-2.69,;-3.48,-3.47,;-2.15,-2.69,;-.82,-3.47,;.52,-2.69,;-6.15,-.38,;-7.61,-.86,;-8.52,.38,;-7.61,1.63,;-8.38,2.96,;-6.15,1.15,)| Show InChI InChI=1S/C21H24N4O2/c1-25-13-18(12-23-25)15-3-4-16-11-22-20(10-17(16)9-15)24-21(26)14-5-7-19(27-2)8-6-14/h3-4,9-14,19H,5-8H2,1-2H3,(H,22,24,26)/t14-,19-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385045 (US10287267, Compound 6 | US10508099, Compound 6 | ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)[C@H]3CC[C@@H](CC3)N3CCOCC3)cc2c1 |r,wU:19.23,wD:16.16,(-9.72,2.58,;-8.95,1.25,;-7.48,.77,;-7.48,-.77,;-8.95,-1.25,;-9.85,,;-6.15,-1.54,;-6.15,-3.08,;-4.82,-3.85,;-3.48,-3.08,;-2.15,-3.85,;-.82,-3.08,;-.82,-1.54,;.52,-.77,;1.85,-1.54,;1.85,-3.08,;3.19,-.77,;4.52,-1.54,;5.85,-.77,;5.85,.77,;4.52,1.54,;3.19,.77,;7.19,1.54,;8.52,.77,;9.85,1.54,;9.85,3.08,;8.52,3.85,;7.19,3.08,;-2.15,-.77,;-3.48,-1.54,;-4.82,-.77,)| Show InChI InChI=1S/C24H29N5O2/c1-28-16-21(15-26-28)18-2-3-19-14-25-23(13-20(19)12-18)27-24(30)17-4-6-22(7-5-17)29-8-10-31-11-9-29/h2-3,12-17,22H,4-11H2,1H3,(H,25,27,30)/t17-,22-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385046 (US10287267, Compound 10 | US10508099, Compound 10 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)[C@H]3CC[C@H](CN4CC(F)C4)CC3)cc2c1 |r,wU:19.20,wD:16.16,(-10.66,3.21,;-9.89,1.88,;-8.43,1.41,;-8.43,-.13,;-9.89,-.61,;-10.8,.64,;-7.09,-.9,;-7.09,-2.44,;-5.76,-3.21,;-4.43,-2.44,;-3.09,-3.21,;-1.76,-2.44,;-1.76,-.9,;-.43,-.13,;.91,-.9,;.91,-2.44,;2.24,-.13,;3.58,-.9,;4.91,-.13,;4.91,1.41,;6.24,2.18,;7.58,1.41,;7.98,-.08,;9.46,.32,;10.8,-.45,;9.06,1.8,;3.58,2.18,;2.24,1.41,;-3.09,-.13,;-4.43,-.9,;-5.76,-.13,)| Show InChI InChI=1S/C24H28FN5O/c1-29-13-21(11-27-29)18-6-7-19-10-26-23(9-20(19)8-18)28-24(31)17-4-2-16(3-5-17)12-30-14-22(25)15-30/h6-11,13,16-17,22H,2-5,12,14-15H2,1H3,(H,26,28,31)/t16-,17-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385054 (US10287267, Compound 14 | US10508099, Compound 14 ...) Show SMILES CN1CCN(C[C@H]2CC[C@@H](CC2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 |r,wU:6.5,wD:9.12,(11.19,-.9,;9.85,-.13,;8.52,-.9,;7.19,-.13,;7.19,1.41,;5.85,2.18,;4.52,1.41,;4.52,-.13,;3.19,-.9,;1.85,-.13,;1.85,1.41,;3.19,2.18,;.52,-.9,;.52,-2.44,;-.82,-.13,;-2.15,-.9,;-3.48,-.13,;-4.82,-.9,;-6.15,-.13,;-7.48,-.9,;-7.48,-2.44,;-6.15,-3.21,;-4.82,-2.44,;-3.48,-3.21,;-2.15,-2.44,;-8.82,-.13,;-10.28,-.61,;-11.19,.64,;-10.28,1.88,;-11.05,3.21,;-8.82,1.41,;8.52,2.18,;9.85,1.41,)| Show InChI InChI=1S/C26H34N6O/c1-30-9-11-32(12-10-30)17-19-3-5-20(6-4-19)26(33)29-25-14-23-13-21(7-8-22(23)15-27-25)24-16-28-31(2)18-24/h7-8,13-16,18-20H,3-6,9-12,17H2,1-2H3,(H,27,29,33)/t19-,20-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385056 (US10287267, Compound 16 | US10508099, Compound 16 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CNC3)cc2c1 Show InChI InChI=1S/C17H17N5O/c1-22-10-15(9-20-22)11-2-3-12-8-19-16(5-13(12)4-11)21-17(23)14-6-18-7-14/h2-5,8-10,14,18H,6-7H2,1H3,(H,19,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385060 (US10287267, Compound 69 | US10508099, Compound 69 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)CN3CC[C@H](F)C3)cc2c1 |r| Show InChI InChI=1S/C19H20FN5O/c1-24-10-16(9-22-24)13-2-3-14-8-21-18(7-15(14)6-13)23-19(26)12-25-5-4-17(20)11-25/h2-3,6-10,17H,4-5,11-12H2,1H3,(H,21,23,26)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385064 (US10287267, Compound 71 | US10508099, Compound 71 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)[C@@H]3CCCO3)cc2c1 |r| Show InChI InChI=1S/C18H18N4O2/c1-22-11-15(10-20-22)12-4-5-13-9-19-17(8-14(13)7-12)21-18(23)16-3-2-6-24-16/h4-5,7-11,16H,2-3,6H2,1H3,(H,19,21,23)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385067 (US10287267, Compound 1085 | US10287267, Compound 7...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCNCC3)cc2c1 Show InChI InChI=1S/C19H21N5O/c1-24-12-17(11-22-24)14-2-3-15-10-21-18(9-16(15)8-14)23-19(25)13-4-6-20-7-5-13/h2-3,8-13,20H,4-7H2,1H3,(H,21,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385069 (US10287267, Compound 73 | US10508099, Compound 73 ...) Show SMILES CN1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C20H23N5O/c1-24-7-5-14(6-8-24)20(26)23-19-10-17-9-15(3-4-16(17)11-21-19)18-12-22-25(2)13-18/h3-4,9-14H,5-8H2,1-2H3,(H,21,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385073 (US10287267, Compound 75 | US10508099, Compound 75 ...) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C22H27N5O/c1-15(2)27-8-6-16(7-9-27)22(28)25-21-11-19-10-17(4-5-18(19)12-23-21)20-13-24-26(3)14-20/h4-5,10-16H,6-9H2,1-3H3,(H,23,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385078 (US10287267, Compound 76 | US10508099, Compound 76 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CC3)C3CC3)cc2c1 Show InChI InChI=1S/C22H25N5O/c1-26-14-19(13-24-26)16-2-3-17-12-23-21(11-18(17)10-16)25-22(28)15-6-8-27(9-7-15)20-4-5-20/h2-3,10-15,20H,4-9H2,1H3,(H,23,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385079 (US10287267, Compound 1086 | US10287267, Compound 1...) Show SMILES CC(C)CN1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H29N5O/c1-16(2)14-28-8-6-17(7-9-28)23(29)26-22-11-20-10-18(4-5-19(20)12-24-22)21-13-25-27(3)15-21/h4-5,10-13,15-17H,6-9,14H2,1-3H3,(H,24,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385080 (US10287267, Compound 78 | US10508099, Compound 78 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CC(C)(C)C)CC3)cc2c1 Show InChI InChI=1S/C24H31N5O/c1-24(2,3)16-29-9-7-17(8-10-29)23(30)27-22-12-20-11-18(5-6-19(20)13-25-22)21-14-26-28(4)15-21/h5-6,11-15,17H,7-10,16H2,1-4H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385081 (US10287267, Compound 81 | US10508099, Compound 81 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CCF)CC3)cc2c1 Show InChI InChI=1S/C21H24FN5O/c1-26-14-19(13-24-26)16-2-3-17-12-23-20(11-18(17)10-16)25-21(28)15-4-7-27(8-5-15)9-6-22/h2-3,10-15H,4-9H2,1H3,(H,23,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385082 (US10287267, Compound 304 | US10287267, Compound 82...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CCC(F)(F)F)CC3)cc2c1 Show InChI InChI=1S/C22H24F3N5O/c1-29-14-19(13-27-29)16-2-3-17-12-26-20(11-18(17)10-16)28-21(31)15-4-7-30(8-5-15)9-6-22(23,24)25/h2-3,10-15H,4-9H2,1H3,(H,26,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385083 (US10287267, Compound 83 | US10508099, Compound 83 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CC(C)(F)F)CC3)cc2c1 Show InChI InChI=1S/C22H25F2N5O/c1-22(23,24)14-29-7-5-15(6-8-29)21(30)27-20-10-18-9-16(3-4-17(18)11-25-20)19-12-26-28(2)13-19/h3-4,9-13,15H,5-8,14H2,1-2H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385084 (US10287267, Compound 84 | US10508099, Compound 84 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CC(F)F)CC3)cc2c1 Show InChI InChI=1S/C21H23F2N5O/c1-27-12-18(11-25-27)15-2-3-16-10-24-20(9-17(16)8-15)26-21(29)14-4-6-28(7-5-14)13-19(22)23/h2-3,8-12,14,19H,4-7,13H2,1H3,(H,24,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385085 (US10287267, Compound 85 | US10508099, Compound 85 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CC(C)(C)F)CC3)cc2c1 Show InChI InChI=1S/C23H28FN5O/c1-23(2,24)15-29-8-6-16(7-9-29)22(30)27-21-11-19-10-17(4-5-18(19)12-25-21)20-13-26-28(3)14-20/h4-5,10-14,16H,6-9,15H2,1-3H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385086 (US10287267, Compound 86 | US10508099, Compound 86 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CC3)C3COC3)cc2c1 Show InChI InChI=1S/C22H25N5O2/c1-26-12-19(11-24-26)16-2-3-17-10-23-21(9-18(17)8-16)25-22(28)15-4-6-27(7-5-15)20-13-29-14-20/h2-3,8-12,15,20H,4-7,13-14H2,1H3,(H,23,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385087 (US10287267, Compound 87 | US10508099, Compound 87 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCN(CC4(C)COC4)CC3)cc2c1 Show InChI InChI=1S/C24H29N5O2/c1-24(15-31-16-24)14-29-7-5-17(6-8-29)23(30)27-22-10-20-9-18(3-4-19(20)11-25-22)21-12-26-28(2)13-21/h3-4,9-13,17H,5-8,14-16H2,1-2H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385088 (US10287267, Compound 89 | US10508099, Compound 89 ...) Show SMILES COCCN1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C22H27N5O2/c1-26-15-20(14-24-26)17-3-4-18-13-23-21(12-19(18)11-17)25-22(28)16-5-7-27(8-6-16)9-10-29-2/h3-4,11-16H,5-10H2,1-2H3,(H,23,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	64	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385089 (US10287267, Compound 90 | US10508099, Compound 90 ...) Show SMILES CC(C)OCCN1CCC(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H31N5O2/c1-17(2)31-11-10-29-8-6-18(7-9-29)24(30)27-23-13-21-12-19(4-5-20(21)14-25-23)22-15-26-28(3)16-22/h4-5,12-18H,6-11H2,1-3H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385090 (US10287267, Compound 91 | US10508099, Compound 91 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3(F)CCNCC3)cc2c1 Show InChI InChI=1S/C19H20FN5O/c1-25-12-16(11-23-25)13-2-3-14-10-22-17(9-15(14)8-13)24-18(26)19(20)4-6-21-7-5-19/h2-3,8-12,21H,4-7H2,1H3,(H,22,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	838	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385091 (US10287267, Compound 92 | US10508099, Compound 92 ...) Show SMILES CN1CCC(F)(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C20H22FN5O/c1-25-7-5-20(21,6-8-25)19(27)24-18-10-16-9-14(3-4-15(16)11-22-18)17-12-23-26(2)13-17/h3-4,9-13H,5-8H2,1-2H3,(H,22,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	361	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385092 (US10287267, Compound 96 | US10508099, Compound 96 ...) Show SMILES CC(C)CN1CCC(F)(CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H28FN5O/c1-16(2)14-29-8-6-23(24,7-9-29)22(30)27-21-11-19-10-17(4-5-18(19)12-25-21)20-13-26-28(3)15-20/h4-5,10-13,15-16H,6-9,14H2,1-3H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385093 (US10287267, Compound 110 | US10508099, Compound 11...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)[C@H]3CCCNC3)cc2c1 |r| Show InChI InChI=1S/C19H21N5O/c1-24-12-17(11-22-24)13-4-5-14-10-21-18(8-16(14)7-13)23-19(25)15-3-2-6-20-9-15/h4-5,7-8,10-12,15,20H,2-3,6,9H2,1H3,(H,21,23,25)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385094 (US10287267, Compound 111 | US10508099, Compound 11...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)[C@@H]3CCCNC3)cc2c1 |r| Show InChI InChI=1S/C19H21N5O/c1-24-12-17(11-22-24)13-4-5-14-10-21-18(8-16(14)7-13)23-19(25)15-3-2-6-20-9-15/h4-5,7-8,10-12,15,20H,2-3,6,9H2,1H3,(H,21,23,25)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385095 (US10287267, Compound 112 | US10508099, Compound 11...) Show SMILES CC(C)CN1CCC[C@@H](C1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 |r| Show InChI InChI=1S/C23H29N5O/c1-16(2)13-28-8-4-5-19(15-28)23(29)26-22-10-20-9-17(6-7-18(20)11-24-22)21-12-25-27(3)14-21/h6-7,9-12,14,16,19H,4-5,8,13,15H2,1-3H3,(H,24,26,29)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	292	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385096 (US10287267, Compound 113 | US10508099, Compound 11...) Show SMILES CC(C)CN1CCC[C@H](C1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 |r| Show InChI InChI=1S/C23H29N5O/c1-16(2)13-28-8-4-5-19(15-28)23(29)26-22-10-20-9-17(6-7-18(20)11-24-22)21-12-25-27(3)14-21/h6-7,9-12,14,16,19H,4-5,8,13,15H2,1-3H3,(H,24,26,29)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	586	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385097 (US10287267, Compound 114 | US10508099, Compound 11...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)C3CCOCC3)cc2c1 Show InChI InChI=1S/C19H20N4O2/c1-23-12-17(11-21-23)14-2-3-15-10-20-18(9-16(15)8-14)22-19(24)13-4-6-25-7-5-13/h2-3,8-13H,4-7H2,1H3,(H,20,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385098 (US10287267, Compound 115 | US10287267, Compound 30...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)CN3CCCCC3)cc2c1 Show InChI InChI=1S/C20H23N5O/c1-24-13-18(12-22-24)15-5-6-16-11-21-19(10-17(16)9-15)23-20(26)14-25-7-3-2-4-8-25/h5-6,9-13H,2-4,7-8,14H2,1H3,(H,21,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385099 (US10287267, Compound 116 | US10508099, Compound 11...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)CN3CCC(F)CC3)cc2c1 Show InChI InChI=1S/C20H22FN5O/c1-25-12-17(11-23-25)14-2-3-15-10-22-19(9-16(15)8-14)24-20(27)13-26-6-4-18(21)5-7-26/h2-3,8-12,18H,4-7,13H2,1H3,(H,22,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385100 (US10287267, Compound 1014 | US10287267, Compound 1...) Show SMILES CN1CCN(CC(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C20H24N6O/c1-24-5-7-26(8-6-24)14-20(27)23-19-10-17-9-15(3-4-16(17)11-21-19)18-12-22-25(2)13-18/h3-4,9-13H,5-8,14H2,1-2H3,(H,21,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385101 (US10287267, Compound 119 | US10508099, Compound 11...) Show SMILES Cc1ncc(-c2ccc3cnc(NC(=O)C4CC4)cc3c2)n1C Show InChI InChI=1S/C18H18N4O/c1-11-19-10-16(22(11)2)13-5-6-14-9-20-17(8-15(14)7-13)21-18(23)12-3-4-12/h5-10,12H,3-4H2,1-2H3,(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385102 (US10287267, Compound 120 | US10508099, Compound 12...) Show SMILES Cc1ncc(-c2ccc3cnc(NC(=O)C4CCCCC4)cc3c2)n1C Show InChI InChI=1S/C21H24N4O/c1-14-22-13-19(25(14)2)16-8-9-17-12-23-20(11-18(17)10-16)24-21(26)15-6-4-3-5-7-15/h8-13,15H,3-7H2,1-2H3,(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	138	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385103 (US10287267, Compound 121 | US10508099, Compound 12...) Show SMILES Cc1ncc(-c2ccc3cnc(NC(=O)C4CCC(F)(F)CC4)cc3c2)n1C Show InChI InChI=1S/C21H22F2N4O/c1-13-24-12-18(27(13)2)15-3-4-16-11-25-19(10-17(16)9-15)26-20(28)14-5-7-21(22,23)8-6-14/h3-4,9-12,14H,5-8H2,1-2H3,(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385104 (US10287267, Compound 188 | US10508099, Compound 18...) Show SMILES Cc1ncc(-c2ccc3cnc(NC(=O)[C@@H]4CCCO4)cc3c2)n1C |r| Show InChI InChI=1S/C19H20N4O2/c1-12-20-11-16(23(12)2)13-5-6-14-10-21-18(9-15(14)8-13)22-19(24)17-4-3-7-25-17/h5-6,8-11,17H,3-4,7H2,1-2H3,(H,21,22,24)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	265	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM385105 (US10287267, Compound 248 | US10508099, Compound 24...) Show SMILES Cn1nncc1-c1ccc2cnc(NC(=O)C3CCN(CCC(F)(F)F)CC3)cc2c1 Show InChI InChI=1S/C21H23F3N6O/c1-29-18(13-26-28-29)15-2-3-16-12-25-19(11-17(16)10-15)27-20(31)14-4-7-30(8-5-14)9-6-21(22,23)24/h2-3,10-14H,4-9H2,1H3,(H,25,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	266	n/a	n/a	n/a	n/a
TBA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z63
					More data for this Ligand-Target Pair

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