Compile Data Set for Download or QSAR

Found 147 hits Enz. Inhib. hit(s) with all data for entry = 10437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443334 (6'-(1-Methyl-1H-indazol-5-yl)-2'-oxo- 1',4'-dihydr...) Show SMILES Cn1ncc2cc(ccc12)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H19N5O/c1-25-19-5-3-15(9-17(19)11-23-25)14-2-4-18-16(8-14)10-21(20(27)24-18)6-7-26(12-21)13-22/h2-5,8-9,11H,6-7,10,12H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535855 (7-(1H-Indazol-4-yl)-2-oxo- 1,2-dihydrospiro[pyrido...) Show SMILES O=C1Nc2cc(cnc2CC11CCN(C1)C#N)-c1cccc2[nH]ncc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535856 (7-(1-Methyl-1H-indazol-4-yl)- 2-oxo-1,2- dihydrosp...) Show SMILES Cn1ncc2c(cccc12)-c1cnc2CC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535857 (7-(1-(2-Hydroxyethyl)-1H- indazol-4-yl)-2-oxo-1,2-...) Show SMILES OCCn1ncc2c(cccc12)-c1cnc2CC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535865 (7-(5-Methyl-1H- indazol-4-yl)- 2-oxo-1,4-dihydro- ...) Show SMILES Cc1ccc2[nH]ncc2c1-c1cnc2CC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443346 (N-(2-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES CC(=O)Nc1ccccc1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H20N4O2/c1-14(26)23-19-5-3-2-4-17(19)15-6-7-18-16(10-15)11-21(20(27)24-18)8-9-25(12-21)13-22/h2-7,10H,8-9,11-12H2,1H3,(H,23,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443347 (6'-(4-(Morpholine-4-carbonyl)phenyl)- 2'-oxo-1',4'...) Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C24H24N4O3/c25-16-27-8-7-24(15-27)14-20-13-19(5-6-21(20)26-23(24)30)17-1-3-18(4-2-17)22(29)28-9-11-31-12-10-28/h1-6,13H,7-12,14-15H2,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443348 (6'-(3-(Morpholinosulfonyl)phenyl)-2'- oxo-1',4'-di...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc(c1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C23H24N4O4S/c24-16-26-7-6-23(15-26)14-19-12-18(4-5-21(19)25-22(23)28)17-2-1-3-20(13-17)32(29,30)27-8-10-31-11-9-27/h1-5,12-13H,6-11,14-15H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443350 (6'-(2-Methylbenzo[d]thiazol-5-yl)-2'- oxo-1',4'-di...) Show SMILES Cc1nc2cc(ccc2s1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H18N4OS/c1-13-23-18-9-15(3-5-19(18)27-13)14-2-4-17-16(8-14)10-21(20(26)24-17)6-7-25(11-21)12-22/h2-5,8-9H,6-7,10-11H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443351 (6'-(3,5-Dimethylisoxazol-4-yl)-2'-oxo- 1',4'-dihyd...) Show SMILES Cc1noc(C)c1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C18H18N4O2/c1-11-16(12(2)24-21-11)13-3-4-15-14(7-13)8-18(17(23)20-15)5-6-22(9-18)10-19/h3-4,7H,5-6,8-9H2,1-2H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443352 (6'-(2-Chloro-5- (trifluoromethoxy)phenyl)-2'-oxo-1...) Show SMILES FC(F)(F)Oc1ccc(Cl)c(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C20H15ClF3N3O2/c21-16-3-2-14(29-20(22,23)24)8-15(16)12-1-4-17-13(7-12)9-19(18(28)26-17)5-6-27(10-19)11-25/h1-4,7-8H,5-6,9-10H2,(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443353 (6'-(4-(4-Methylpiperazin-1-yl)phenyl)- 2'-oxo-1',4...) Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C24H27N5O/c1-27-10-12-29(13-11-27)21-5-2-18(3-6-21)19-4-7-22-20(14-19)15-24(23(30)26-22)8-9-28(16-24)17-25/h2-7,14H,8-13,15-16H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443354 (N-Benzyl-4-(1-cyano-2'-oxo-1',4'- dihydro-2'H-spir...) Show SMILES O=C(NCc1ccccc1)c1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C27H24N4O2/c28-18-31-13-12-27(17-31)15-23-14-22(10-11-24(23)30-26(27)33)20-6-8-21(9-7-20)25(32)29-16-19-4-2-1-3-5-19/h1-11,14H,12-13,15-17H2,(H,29,32)(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443355 (6'-(3-Methyl-1H-pyrazol-4-yl)-2'-oxo- 1',4'-dihydr...) Show SMILES Cc1n[nH]cc1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443356 (6'-(4-(Morpholinomethyl)phenyl)-2'- oxo-1',4'-dihy...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C24H26N4O2/c25-17-28-8-7-24(16-28)14-21-13-20(5-6-22(21)26-23(24)29)19-3-1-18(2-4-19)15-27-9-11-30-12-10-27/h1-6,13H,7-12,14-16H2,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535750 (3-(1-Cyano-2'-oxo-1'4'- dihydro-2'H- spiro$#9484;p...) Show SMILES CN(C)C(=O)c1cccc(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535754 (7'-(2-Methylpyridin-4-yl)-2'- oxo-1',4'-dihydro-2'...) Show SMILES Cc1cc(ccn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443359 ((R)-7′-(5-Methyl-H-indazol-4-yl)-2′-ox...) Show SMILES Cc1ccc2[nH]ncc2c1-c1ccc2C[C@]3(CCN(C3)C#N)C(=O)Nc2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443360 (7′-(1H-Indazol-4-yl)-2′-oxo-1′,4...) Show SMILES O=C1Nc2cc(ccc2CC11CCN(C1)C#N)-c1cccc2[nH]ncc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443361 (6′-(1H-Indazol-4-yl)-2′-oxo-1′,4...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc2[nH]ncc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535858 (7-(6-Methoxy-2- methylpyridin-3-yl)-2-oxo- 1,2-dih...) Show SMILES COc1ccc(c(C)n1)-c1cnc2CC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443366 (6-(1H-Indazol-4-yl)-2-oxo-1,2-dihydrospiro[pyrido[...) Show SMILES O=C1Nc2ccc(nc2OC11CCN(C1)C#N)-c1cccc2[nH]ncc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443367 (7-(1-(2-Methoxyethyl)-1H-indazol-4-yl)-2-oxo-1,2-d...) Show SMILES COCCn1ncc2c(cccc12)-c1cnc2OC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI InChI=1S/C21H20N6O3/c1-29-8-7-27-18-4-2-3-15(16(18)11-24-27)14-9-17-19(23-10-14)30-21(20(28)25-17)5-6-26(12-21)13-22/h2-4,9-11H,5-8,12H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443370 (1′-Cyano-2-oxo-N-phenyl-1,2-dihydrospiro[pyr...) Show SMILES O=C(Nc1ccccc1)c1ccc2NC(=O)C3(CCN(C3)C#N)Oc2n1 Show InChI InChI=1S/C18H15N5O3/c19-11-23-9-8-18(10-23)17(25)22-14-7-6-13(21-16(14)26-18)15(24)20-12-4-2-1-3-5-12/h1-7H,8-10H2,(H,20,24)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443371 (1′-Cyano-N-(2-fluorophenyl)-2-oxo-1,2-dihydr...) Show SMILES Fc1ccccc1NC(=O)c1ccc2NC(=O)C3(CCN(C3)C#N)Oc2n1 Show InChI InChI=1S/C18H14FN5O3/c19-11-3-1-2-4-12(11)21-15(25)13-5-6-14-16(22-13)27-18(17(26)23-14)7-8-24(9-18)10-20/h1-6H,7-9H2,(H,21,25)(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535866 (7-(1,4-Dimethyl- 1H-pyrazol-5- yl)-2-oxo- 1,4-dihy...) Show SMILES Cc1cnn(C)c1-c1cnc2CC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535736 (7'-(2-(Benzyloxy)phenyl)-2'- oxo-1',4'-dihydro-2'H...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1ccccc1OCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535738 (7'-(3-((2- Chlorobenzyl)oxy)phenyl)-2'- oxo-1',4'-...) Show SMILES Clc1ccccc1COc1ccccc1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443353 (6'-(4-(4-Methylpiperazin-1-yl)phenyl)- 2'-oxo-1',4...) Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C24H27N5O/c1-27-10-12-29(13-11-27)21-5-2-18(3-6-21)19-4-7-22-20(14-19)15-24(23(30)26-22)8-9-28(16-24)17-25/h2-7,14H,8-13,15-16H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443331 (6'-(5-Fluoro-2-isopropoxyphenyl)-2'- oxo-1',4'-dih...) Show SMILES CC(C)Oc1ccc(F)cc1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C22H22FN3O2/c1-14(2)28-20-6-4-17(23)10-18(20)15-3-5-19-16(9-15)11-22(21(27)25-19)7-8-26(12-22)13-24/h3-6,9-10,14H,7-8,11-12H2,1-2H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535742 (7'-(3-Methyl-1H-indazol-6-yl)- 2'-oxo-1',4'-dihydr...) Show SMILES Cc1n[nH]c2cc(ccc12)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443333 (6'-(4-(4-Methylpiperazine-1- carbonyl)phenyl)-2'-o...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C25H27N5O2/c1-28-10-12-30(13-11-28)23(31)19-4-2-18(3-5-19)20-6-7-22-21(14-20)15-25(24(32)27-22)8-9-29(16-25)17-26/h2-7,14H,8-13,15-16H2,1H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443361 (6′-(1H-Indazol-4-yl)-2′-oxo-1′,4...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc2[nH]ncc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443336 (N-(3-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc(NS(=O)(=O)C2CC2)c1 Show InChI InChI=1S/C22H22N4O3S/c23-14-26-9-8-22(13-26)12-17-10-16(4-7-20(17)24-21(22)27)15-2-1-3-18(11-15)25-30(28,29)19-5-6-19/h1-4,7,10-11,19,25H,5-6,8-9,12-13H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443338 (2'-Oxo-6'-(pyrimidin-5-yl)-1',4'- dihydro-2'H-spir...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cncnc1 Show InChI InChI=1S/C17H15N5O/c18-10-22-4-3-17(9-22)6-13-5-12(14-7-19-11-20-8-14)1-2-15(13)21-16(17)23/h1-2,5,7-8,11H,3-4,6,9H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535750 (3-(1-Cyano-2'-oxo-1'4'- dihydro-2'H- spiro$#9484;p...) Show SMILES CN(C)C(=O)c1cccc(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443346 (N-(2-(1-Cyano-2'-oxo-1',4'-dihydro- 2'H-spiro[pyrr...) Show SMILES CC(=O)Nc1ccccc1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H20N4O2/c1-14(26)23-19-5-3-2-4-17(19)15-6-7-18-16(10-15)11-21(20(27)24-18)8-9-25(12-21)13-22/h2-7,10H,8-9,11-12H2,1H3,(H,23,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443350 (6'-(2-Methylbenzo[d]thiazol-5-yl)-2'- oxo-1',4'-di...) Show SMILES Cc1nc2cc(ccc2s1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C21H18N4OS/c1-13-23-18-9-15(3-5-19(18)27-13)14-2-4-17-16(8-14)10-21(20(26)24-17)6-7-25(11-21)12-22/h2-5,8-9H,6-7,10-11H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443268 (US10654853, Example 41 | US10654853, Example 44 | ...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1ccccc1 Show InChI InChI=1S/C19H17N3O/c20-13-22-9-8-19(12-22)11-16-10-15(14-4-2-1-3-5-14)6-7-17(16)21-18(19)23/h1-7,10H,8-9,11-12H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443269 (6'-(4-Cyanophenyl)- 2'-oxo-1',4'-dihydro- 2'H-spir...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1ccc(cc1)C#N Show InChI InChI=1S/C20H16N4O/c21-11-14-1-3-15(4-2-14)16-5-6-18-17(9-16)10-20(19(25)23-18)7-8-24(12-20)13-22/h1-6,9H,7-8,10,12H2,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443270 (6'-(3-Cyanophenyl)- 2'-oxo-1',4'-dihydro- 2'H-spir...) Show SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1cccc(c1)C#N Show InChI InChI=1S/C20H16N4O/c21-11-14-2-1-3-15(8-14)16-4-5-18-17(9-16)10-20(19(25)23-18)6-7-24(12-20)13-22/h1-5,8-9H,6-7,10,12H2,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM535764 (6'-(4-Fluorophenyl)-2'-oxo- 1',4'-dihydro-2'H- spi...) Show SMILES Fc1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443272 (6'-(3-Fluorophenyl)- 2'-oxo-1',4'-dihydro- 2'H-spi...) Show SMILES Fc1cccc(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C19H16FN3O/c20-16-3-1-2-13(9-16)14-4-5-17-15(8-14)10-19(18(24)22-17)6-7-23(11-19)12-21/h1-5,8-9H,6-7,10-11H2,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443275 (US10654853, Example 48 | US11236092, Example 48) Show SMILES O=C1Nc2cccnc2OC11CCN(C1)C#N Show InChI InChI=1S/C11H10N4O2/c12-7-15-5-3-11(6-15)10(16)14-8-2-1-4-13-9(8)17-11/h1-2,4H,3,5-6H2,(H,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443276 (2-Oxo-7-phenyl-1,2-dihydrospiro[pyrido[2,3-b][1,4]...) Show SMILES O=C1Nc2cc(cnc2OC11CCN(C1)C#N)-c1ccccc1 Show InChI InChI=1S/C17H14N4O2/c18-11-21-7-6-17(10-21)16(22)20-14-8-13(9-19-15(14)23-17)12-4-2-1-3-5-12/h1-5,8-9H,6-7,10H2,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443277 (7-(4-Cyanophenyl)-2-oxo- 1,2-dihydrospiro[pyrido [...) Show SMILES O=C1Nc2cc(cnc2OC11CCN(C1)C#N)-c1ccc(cc1)C#N Show InChI InChI=1S/C18H13N5O2/c19-8-12-1-3-13(4-2-12)14-7-15-16(21-9-14)25-18(17(24)22-15)5-6-23(10-18)11-20/h1-4,7,9H,5-6,10H2,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443278 (7-(3-Cyanophenyl)-2-oxo- 1,2-dihydrospiro[pyrido [...) Show SMILES O=C1Nc2cc(cnc2OC11CCN(C1)C#N)-c1cccc(c1)C#N Show InChI InChI=1S/C18H13N5O2/c19-8-12-2-1-3-13(6-12)14-7-15-16(21-9-14)25-18(17(24)22-15)4-5-23(10-18)11-20/h1-3,6-7,9H,4-5,10H2,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443279 (7-(4-Fluorophenyl)-2-oxo- 1,2-dihydrospiro[pyrido ...) Show SMILES Fc1ccc(cc1)-c1cnc2OC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI InChI=1S/C17H13FN4O2/c18-13-3-1-11(2-4-13)12-7-14-15(20-8-12)24-17(16(23)21-14)5-6-22(9-17)10-19/h1-4,7-8H,5-6,9H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443280 (7-(3-Fluorophenyl)-2-oxo- 1,2-dihydrospiro[pyrido ...) Show SMILES Fc1cccc(c1)-c1cnc2OC3(CCN(C3)C#N)C(=O)Nc2c1 Show InChI InChI=1S/C17H13FN4O2/c18-13-3-1-2-11(6-13)12-7-14-15(20-8-12)24-17(16(23)21-14)4-5-22(9-17)10-19/h1-3,6-8H,4-5,9H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443281 (2-Oxo-6-phenyl-1,2-dihydrospiro[pyrido[2,3-b][1,4]...) Show SMILES O=C1Nc2ccc(nc2OC11CCN(C1)C#N)-c1ccccc1 Show InChI InChI=1S/C17H14N4O2/c18-11-21-9-8-17(10-21)16(22)20-14-7-6-13(19-15(14)23-17)12-4-2-1-3-5-12/h1-7H,8-10H2,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair

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