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Compile Data Set for Download or QSAR

Found 98 hits Enz. Inhib. hit(s) with all data for entry = 10455   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536422
PNG
((S)-5-(1-(2-((3-chloro-6- (2,4-dimethylpiperazin- ...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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US Patent
n/an/an/a 5.85n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536423
PNG
((S)-3-chloro-5-(1-(2-((5- chloro-2-(3-methyl- morp...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
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UniProtKB/SwissProt

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n/an/an/a 4.48n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536424
PNG
((S)-5-(1-(2-((5-chloro- 2-(3-methylmorpho- lino)py...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
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UniProtKB/SwissProt

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n/an/an/a 25.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536425
PNG
((S)-5-(1-(2-((5-chloro-2- (2,4-dimethylpiperazin-1...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
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UniProtKB/SwissProt

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n/an/an/a 23.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536426
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(3-methyl- morp...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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UniProtKB/SwissProt

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n/an/an/a 11.7n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536427
PNG
((S)-5-(1-(2-((5-chloro-2- (4-(cyclopropylmethyl)- ...)
Show SMILES C[C@H]1CN(CC2CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
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UniProtKB/SwissProt

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n/an/an/a 25.9n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536428
PNG
((S)-5-(1-(2-((5-chloro- 2-(2-methyl-4-(oxetan- 3-y...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1)C1COC1 |r|
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UniProtKB/SwissProt

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n/an/an/a 17.6n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536429
PNG
((S)-3-chloro-5-(1-(2- ((5-chloro-2-(2,4- dimethylp...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(Cl)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
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UniProtKB/SwissProt

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n/an/an/a 5.27n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536430
PNG
((S)-5-(1-(2-((5-chloro-2- (2-methyl-4-((1-methyl- ...)
Show SMILES C[C@H]1CN(CC2(C)CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
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UniProtKB/SwissProt

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n/an/an/a 56.8n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536431
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-6-(2,4- dimethylp...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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UniProtKB/SwissProt

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n/an/an/a 49.7n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536432
PNG
((S)-3-chloro-5-(1-(2-((3- chloro-2-fluoro-6-(3- me...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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UniProtKB/SwissProt

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n/an/an/a 112n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536433
PNG
((S)-3-chloro-5-(1-(2-((5- chloro-2-(2,4-dimethyl- ...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 111n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536434
PNG
((S)-3-chloro-5-(1-(2- ((5-chloro-2-(3-methyl- morp...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 111n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536435
PNG
((S)-3-chloro-5-(1-(2- ((5-chloro-2-(2-methyl- 4-(o...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1)C1COC1 |r|
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n/an/an/a 58.1n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536436
PNG
((S)-5-(1-(2-((3-chloro-6- (2,4-dimethylpiperazin- ...)
Show SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(nc(F)c3Cl)N3CCN(C)C[C@@H]3C)c3nc4CCCn4c(=O)c23)c1F)C(N)=O |r|
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n/an/an/a 34.1n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536437
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(3-methyl- morp...)
Show SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(nc(F)c3Cl)N3CCOC[C@@H]3C)c3nc4CCCn4c(=O)c23)c1F)C(N)=O |r|
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n/an/an/a 34.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536438
PNG
((S)-5-(1-(2-((5-chloro- 2-(2,4-dimethyl- piperazin...)
Show SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(ncc3Cl)N3CCN(C)C[C@@H]3C)c3nc4CCCn4c(=O)c23)c1F)C(N)=O |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 49.6n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536439
PNG
((S)-5-(1-(2-((5-chloro- 2-(3-methylmorpholino) pyr...)
Show SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(ncc3Cl)N3CCOC[C@@H]3C)c3nc4CCCn4c(=O)c23)c1F)C(N)=O |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 34.3n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536440
PNG
((S)-5-(1-(2-((5-chloro- 2-(2-methyl-4-(oxetan-3- y...)
Show SMILES COc1c(O)c(cc(-c2cn(CC(=O)Nc3cc(ncc3Cl)N3CCN(C[C@@H]3C)C3COC3)c3nc4CCCn4c(=O)c23)c1F)C(N)=O |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 26.6n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536441
PNG
((S)-5-(1-(2-((3-chloro-2- fluoro-6-(2-methyl-4- (o...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1)C1COC1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 3.96n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536442
PNG
(5-(1-(2-((5-chloro-2- (2,4,6-trimethyl- piperazin-...)
Show SMILES CC1CN(C)CC(C)N1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1
PDB

UniProtKB/SwissProt

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n/an/an/a 25.6n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536443
PNG
(5-(1-(2-((3-chloro-6- (dimethylamino)-2- fluoropyr...)
Show SMILES CN(C)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1
PDB

UniProtKB/SwissProt

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n/an/an/a 11.8n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536444
PNG
((S)-5-(1-(2-((3-chloro-6- (4-ethyl-2-methyl- piper...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 7.97n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536445
PNG
((S)-5-(1-(2-((3-chloro-6- (4-(cyclopropylmethyl)- ...)
Show SMILES C[C@H]1CN(CC2CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 12.3n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536446
PNG
((S)-5-(1-(2-((3-chloro-2- fluoro-6-(4-(2- methoxye...)
Show SMILES COCCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 5.64n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536447
PNG
((S)-3-chloro-5-(1-(2-((3- chloro-2-fluoro-6-(2- me...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1)C1COC1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 30.2n/an/an/an/an/a


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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536448
PNG
(3-chloro-5-(1-(2-((3- chloro-6-(dimethyl- amino)-2...)
Show SMILES CN(C)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1
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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536449
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-6-(4-ethyl- 2-met...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 135n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536450
PNG
((S)-3-chloro-5-(1-(2- ((3-chloro-6-(4- (cyclopropy...)
Show SMILES C[C@H]1CN(CC2CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(Cl)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
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TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536451
PNG
(5-(1-(2-((2-chloro-4- fluoro-5-morpholino- phenyl)...)
Show SMILES NC(=O)c1cc(-c2cn(CC(=O)Nc3cc(N4CCOCC4)c(F)cc3Cl)c3nc4CCCn4c(=O)c23)c(F)c(F)c1O
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n/an/an/a 106n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536452
PNG
(5-(1-(2-((2-chloro-5- morpholinophenyl) amino)-2-o...)
Show SMILES NC(=O)c1cc(-c2cn(CC(=O)Nc3cc(ccc3Cl)N3CCOCC3)c3nc4CCCn4c(=O)c23)c(F)c(F)c1O
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Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536453
PNG
(5-(1-(2-((2-chloro-5-(4- methylpiperazin-1-yl) phe...)
Show SMILES CN1CCN(CC1)c1ccc(Cl)c(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c1
PDB

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n/an/an/a 261n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536454
PNG
((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethylpiperazin- ...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2COCCn2c3=O)c(Cl)c(F)n1 |r|
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n/an/an/a 11n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536455
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- 4-(o...)
Show SMILES C[C@H]1CN(CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2COCCn2c3=O)c(Cl)c(F)n1)C1COC1 |r|
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TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536456
PNG
((S)-5-(1-(2-((5-chloro- 2-(2-methyl-4-(3,3,3- trif...)
Show SMILES C[C@H]1CN(CCC(F)(F)F)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
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n/an/an/a 24.3n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536457
PNG
(5-(1-(2-((5-chloro-2- (4-methylpiperazin-1- yl)pyr...)
Show SMILES CN1CCN(CC1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1
PDB

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n/an/an/a 23.2n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536459
PNG
(5-(1-(2-((3-chloro-6- ((S)-4-((S)-1-cyclo- propyle...)
Show SMILES C[C@@H](C1CC1)N1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 32.5n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536460
PNG
(5-(1-(2-((3-chloro-6- ((S)-4-((R)-1-cyclo- propyle...)
Show SMILES C[C@H](C1CC1)N1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 34.9n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536461
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(2-methyl- 4-(3...)
Show SMILES C[C@H]1CN(CCC(F)(F)F)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 134n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536463
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(3-methyl- morp...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 29n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536464
PNG
((S)-5-(1-(2-((3-chloro- 6-(4-ethyl-2-methyl- piper...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 42.8n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536466
PNG
((S)-5-(1-(2-((3-chloro- 6-(4-(cyclopropyl- methyl)...)
Show SMILES C[C@H]1CN(CC2CC2)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 31.8n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536467
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(4-(3- hydroxy-...)
Show SMILES C[C@H]1CN(CC(CO)CO)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 3.13n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536469
PNG
((S)-5-(1-(2-((3-chloro- 6-(4-(2,2-difluoroethyl)- ...)
Show SMILES C[C@H]1CN(CC(F)F)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 13.7n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536470
PNG
((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethyl- piperazin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 46.6n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536472
PNG
((S)-5-(1-(2-((3-chloro- 2-fluoro-6-(3-methyl- morp...)
Show SMILES C[C@H]1COCCN1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

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n/an/an/a 89.1n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536473
PNG
((S)-5-(1-(2-((3-chloro- 6-(4-ethyl-2-methyl- piper...)
Show SMILES CCN1CCN([C@@H](C)C1)c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 76.5n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536475
PNG
(5-(1-(2-((5-chloro-2- ((2S,6S)-2,4,6- trimethylpip...)
Show SMILES C[C@H]1CN(C)C[C@H](C)N1c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 97.6n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536476
PNG
((S)-5-(1-(2-((3-chloro- 6-(2,4-dimethyl- piperazin...)
Show SMILES C[C@H]1CN(C)CCN1c1cc(NC(=O)Cn2cc(-c3cc(F)c(O)c(c3)C(N)=O)c3c2nc2CCCn2c3=O)c(Cl)c(F)n1 |r|
PDB

UniProtKB/SwissProt

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n/an/an/a 1.5n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
B-cell lymphoma 6 protein [1-129]/Nuclear receptor corepressor 2 [1414-1429]


(Homo sapiens-Homo sapiens (Human))
BDBM536477
PNG
(5-(1-(2-((5-chloro-2- ((1R,5S)-3-methyl- 3,8-diaza...)
Show SMILES CN1CC2CCC(C1)N2c1cc(NC(=O)Cn2cc(-c3cc(C(N)=O)c(O)c(F)c3F)c3c2nc2CCCn2c3=O)c(Cl)cn1 |TLB:0:1:8:4.5|
PDB

UniProtKB/SwissProt

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n/an/an/a 38.7n/an/an/an/an/a


TBA

Assay Description
This assay was used to determine whether compounds inhibit the interaction between the BTB domain of BCL6 and a peptide derived from the BCL6 binding...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Z60S71
More data for this
Ligand-Target Pair
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