Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552911![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552939![]() ((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50270877![]() ((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM60828![]() (ABT-199 | BDBM189459 | US10213433, Compound 5 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555343![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552914![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555320![]() (2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552934![]() ((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552934![]() ((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552931![]() ((R)-4-(4-((5,5-dimethyl-2-(3-methylbicyclo[1.1.1]p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552931![]() ((R)-4-(4-((5,5-dimethyl-2-(3-methylbicyclo[1.1.1]p...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552935![]() ((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552935![]() ((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552936![]() ((R)-4-(4-((2-(3-Ethylbicyclo[1.1.1]pentan-1-yl)-4,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552936![]() ((R)-4-(4-((2-(3-Ethylbicyclo[1.1.1]pentan-1-yl)-4,...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555333![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555333![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555334![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555334![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552939![]() ((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM50270877![]() ((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555336![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555336![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555337![]() ((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555337![]() ((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555338![]() ((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555338![]() ((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555339![]() ((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555339![]() ((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555340![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555340![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552945![]() ((R)-4-(4-((6-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552945![]() ((R)-4-(4-((6-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555342![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555342![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM555343![]() ((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM60828![]() (ABT-199 | BDBM189459 | US10213433, Compound 5 | US...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM555320![]() (2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552914![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552911![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552906![]() (2-(1H-Pyrrolo[2,3-b]pyridin-5-yl-oxy)-4-(4-((2-(3-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552906![]() (2-(1H-Pyrrolo[2,3-b]pyridin-5-yl-oxy)-4-(4-((2-(3-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552907![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552907![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552908![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(3-f...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552908![]() (2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(3-f...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552909![]() (2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-(((7-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552909![]() (2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-(((7-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM552910![]() (2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl2-associated agonist of cell death (Homo sapiens (Human)) | BDBM552910![]() (2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QR51BH | |||||||||||
More data for this Ligand-Target Pair |
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