Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577554 (2-[[1-[(1 R)-2,2-Difluoro-1-methyl-ethyl]-3-(oxeta...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577560 (7-[(3R,4R)-4-Methyltetrahydrofuran-3-yl]-2-[[1-(ox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577560 (7-[(3R,4R)-4-Methyltetrahydrofuran-3-yl]-2-[[1-(ox...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577575 (2-((1-Methyl-3-(oxetan-3-yloxy)-1 H-pyrazol-4-yl)a...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577554 (2-[[1-[(1 R)-2,2-Difluoro-1-methyl-ethyl]-3-(oxeta...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577571 (2-((1-Methyl-3-(((R)-1 ,1 ,1-trifluoropropan-2-yl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577571 (2-((1-Methyl-3-(((R)-1 ,1 ,1-trifluoropropan-2-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577564 (2-[[1-(Methylsulfonylmethyl)-3-(oxetan-3-yloxy)pyr...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577564 (2-[[1-(Methylsulfonylmethyl)-3-(oxetan-3-yloxy)pyr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577568 (2-((3-(((S)-1-acetyl-2,2-dimethylazetidin-3-yl)oxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577568 (2-((3-(((S)-1-acetyl-2,2-dimethylazetidin-3-yl)oxy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577570 (2-((4-(2-Hydroxypropan-2-yl)-2-(oxetan-3-yloxy)phe...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577570 (2-((4-(2-Hydroxypropan-2-yl)-2-(oxetan-3-yloxy)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577567 (2-((3-(((R)-1 -Acetyl-2, 2-dimethylazetidin-3-yl)o...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577567 (2-((3-(((R)-1 -Acetyl-2, 2-dimethylazetidin-3-yl)o...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577553 (2-[[1 -methyl-3-[(3S,4R)-4-methyltetrahydrofuran-3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577555 (2-[[1 -[(1 S)-2,2-difluoro-1 -methyl-ethyl]-3-(oxe...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577574 (2-((1 -(methyl-d3)-3-(((2S,3S)-2-methyloxetan-3-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577587 (2-((1-((S)-1-Cyanoethyl)-3-isopropoxy-1 H-pyrazol-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577555 (2-[[1 -[(1 S)-2,2-difluoro-1 -methyl-ethyl]-3-(oxe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577553 (2-[[1 -methyl-3-[(3S,4R)-4-methyltetrahydrofuran-3...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577559 (2-[[1-[2-Hydroxy-1-methyl-ethyl]-3-(oxetan-3-yloxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577552 (2-[[1-Methyl-3-[(3R,4S)-4-methyltetrahydrofuran-3-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577552 (2-[[1-Methyl-3-[(3R,4S)-4-methyltetrahydrofuran-3-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577556 (2-((1-Methyl-3-(((2R,3S)-2-methyloxetan-3-yl)oxy)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577559 (2-[[1-[2-Hydroxy-1-methyl-ethyl]-3-(oxetan-3-yloxy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577582 ((R)-2-((1-Methyl-3-(oxetan-3-yloxy)-1 H-pyrazol-4-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description LRRK2(human) is incubated with 50 mM HEPES pH 8.0, 0.2 mM EDTA, 0.01 %Brij-35, 1% (w/v) BSA, 5 mM DTT, 250 Mm RLGRDKYKTLRQIRQ, 10 mM Magnesium aceta... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577551 (2-[[3-(1-acetylazetidin-3-yl)oxy-1-methyl-pyrazol-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577574 (2-((1 -(methyl-d3)-3-(((2S,3S)-2-methyloxetan-3-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577562 (2-[[3-[(3R,4R)-4-Methoxytetrahydrofuran-3-yl]oxy-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577558 (WO2022263472, Example 19 | WO2022263472, Example 8) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577551 (2-[[3-(1-acetylazetidin-3-yl)oxy-1-methyl-pyrazol-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577599 (WO2022263472, Example 80) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577557 (2-((1-methyl-3-(((2S,3R)-2-methyloxetan-3-yl)oxy)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577581 (2-((1-((S)-1-cyanoethyl)-3-isopropoxy-1H-pyrazol-4...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description LRRK2(human) is incubated with 50 mM HEPES pH 8.0, 0.2 mM EDTA, 0.01 %Brij-35, 1% (w/v) BSA, 5 mM DTT, 250 Mm RLGRDKYKTLRQIRQ, 10 mM Magnesium aceta... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577587 (2-((1-((S)-1-Cyanoethyl)-3-isopropoxy-1 H-pyrazol-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577573 (2-((1-(Methyl-d3)-3-(((2R,3R)-2-methyloxetan-3-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577562 (2-[[3-[(3R,4R)-4-Methoxytetrahydrofuran-3-yl]oxy-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM577563 (2-[[3-[(3S,4S)-4-methoxytetrahydrofuran-3-yl]oxy-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577599 (WO2022263472, Example 80) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM577573 (2-((1-(Methyl-d3)-3-(((2R,3R)-2-methyloxetan-3-yl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022263472 | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e... | Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ | |||||||||||
More data for this Ligand-Target Pair |
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