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Compile Data Set for Download or QSAR

Found 238 hits Enz. Inhib. hit(s) with all data for entry = 11069   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585854
PNG
(US11530237, Compound 10 | US11542297, Compound 10)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc(cn1)C#N |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM586079
PNG
(US11530237, Compound 260 | US11542297, Compound 26...)
Show SMILES CCCN(C)C(=O)c1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585856
PNG
(US11530237, Compound 12 | US11542297, Compound 12)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccccc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585858
PNG
(US11530237, Compound 14 | US11542297, Compound 14)
Show SMILES COc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585859
PNG
(US11530237, Compound 15 | US11542297, Compound 15)
Show SMILES COc1ccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc2c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585877
PNG
(US11530237, Compound 35 | US11542297, Compound 35)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(Cl)cc2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM588646
PNG
(US11542297, Compound 50)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cc(Cl)cnc2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585895
PNG
(US11530237, Compound 54 | US11542297, Compound 54)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ncnn1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585946
PNG
(US11530237, Compound 117 | US11542297, Compound 11...)
Show SMILES COc1cccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM588727
PNG
(US11542297, Compound 146)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc(cn1)[N+]([O-])=O |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM586009
PNG
(US11530237, Compound 185 | US11542297, Compound 18...)
Show SMILES COC[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5nnc6ccc(Cl)cc56)[C@@]4(C)CC[C@H]23)C1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585860
PNG
(US11530237, Compound 16 | US11542297, Compound 16)
Show SMILES COc1ccc2nnn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)c2c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585862
PNG
(US11530237, Compound 18 | US11542297, Compound 18)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2c(F)cccc12 |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585863
PNG
(US11530237, Compound 19 | US11542297, Compound 19)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ccc(n1)C(F)(F)F |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585864
PNG
(US11530237, Compound 21 | US11542297, Compound 21)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(F)cc2n1 |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585865
PNG
(US11530237, Compound 22 | US11542297, Compound 22)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccc(F)cc12 |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585866
PNG
(US11530237, Compound 23 | US11542297, Compound 23)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)ccc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585867
PNG
(US11530237, Compound 24 | US11542297, Compound 24)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ccc(n1)C#N |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585868
PNG
(US11530237, Compound 26 | US11542297, Compound 26)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc2ccccc2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585870
PNG
(US11530237, Compound 28 | US11542297, Compound 28)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cc(F)cc(F)c2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585871
PNG
(US11530237, Compound 29 | US11542297, Compound 29)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)cc(F)c12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM588629
PNG
(US11542297, Compound 32)
Show SMILES Cc1nnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585878
PNG
(US11530237, Compound 36 | US11542297, Compound 36)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccc(Cl)cc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585882
PNG
(US11530237, Compound 40 | US11542297, Compound 40)
Show SMILES CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5ccc(n5)C(=O)OCC)[C@@]4(C)CC[C@H]23)C[C@@H]1O |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585886
PNG
(US11530237, Compound 45 | US11542297, Compound 45)
Show SMILES COc1cccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585894
PNG
(US11530237, Compound 53 | US11542297, Compound 53)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(Cl)c(F)c2n1 |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585915
PNG
(US11530237, Compound 74 | US11542297, Compound 74)
Show SMILES CSc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585919
PNG
(US11530237, Compound 78 | US11542297, Compound 78)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2c(F)c(F)ccc12 |r|
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n/an/a<10n/an/an/an/an/an/a


TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM588678
PNG
(US11542297, Compound 86)
Show SMILES CN(C)C(=O)c1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM588688
PNG
(US11542297, Compound 103)
Show SMILES CS(=O)c1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM588689
PNG
(US11542297, Compound 104)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(cc2n1)S(C)(=O)=O |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585951
PNG
(US11530237, Compound 124 | US11542297, Compound 12...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)c(F)cc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585939
PNG
(US11530237, Compound 110 | US11530237, Compound 12...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cccc(F)c2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585959
PNG
(US11530237, Compound 133 | US11542297, Compound 13...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc(Cl)cn1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585990
PNG
(US11530237, Compound 165 | US11542297, Compound 16...)
Show SMILES COC[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5nc6ccc(Cl)cc6n5)[C@@]4(C)CC[C@H]23)C1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM586015
PNG
(US11530237, Compound 191 | US11542297, Compound 19...)
Show SMILES COC[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5cc6cc(Cl)ccc6n5)[C@@]4(C)CC[C@H]23)C1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM586026
PNG
(US11530237, Compound 204 | US11542297, Compound 20...)
Show SMILES CCOC(=O)c1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585939
PNG
(US11530237, Compound 110 | US11530237, Compound 12...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cccc(F)c2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM588823
PNG
(US11542297, Compound 248)
Show SMILES CSc1ccc2cnn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)c2c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM586067
PNG
(US11530237, Compound 248 | US11542297, Compound 24...)
Show SMILES CSc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM586078
PNG
(US11530237, Compound 259 | US11542297, Compound 25...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cnc(F)c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585855
PNG
(US11530237, Compound 11 | US11542297, Compound 11)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccccc2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585846
PNG
(US11530237, Compound 2 | US11542297, Compound 2)
Show SMILES CO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5nccn5)[C@@]4(C)CC[C@H]23)C[C@@H]1O |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585857
PNG
(US11530237, Compound 13 | US11542297, Compound 13)
Show SMILES Cc1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585881
PNG
(US11530237, Compound 39 | US11542297, Compound 39)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ncc2cc(F)ccc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585888
PNG
(US11530237, Compound 47 | US11542297, Compound 47)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc2ccc(Cl)cc2n1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585906
PNG
(US11530237, Compound 65 | US11542297, Compound 65)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ncc2nccnc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585909
PNG
(US11530237, Compound 68 | US11542297, Compound 68)
Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)c(F)cc12 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585913
PNG
(US11530237, Compound 72 | US11542297, Compound 72)
Show SMILES C[C@H](C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C)n1cc(cn1)C#N |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit gamma-1


(Rattus norvegicus)
BDBM585916
PNG
(US11530237, Compound 75 | US11542297, Compound 75)
Show SMILES CSc1ccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc2c1 |r|
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TBA

Assay Description
Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2VD73BW
More data for this
Ligand-Target Pair
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