Compile Data Set for Download or QSAR

Found 432 hits Enz. Inhib. hit(s) with all data for entry = 11162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM596415 (US11591338, Example 91) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(c([nH]1)C(\N)=N/C=N)-c1ccc(NC(=O)c2cn(C(C)C)c(=O)n(-c3cccc(c3)C#N)c2=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397030 (US10442810, Example 94 | US10844069, Example 94 | ...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(cc2)-c2cc(C3CN(C3)C(=O)C3CC3)n3ncnc(N)c23)c(=O)n(-c2ccccc2)c1=O Show InChI InChI=1S/C33H32N8O4/c1-19(2)39-17-26(32(44)40(33(39)45)24-6-4-3-5-7-24)30(42)37-23-12-10-20(11-13-23)25-14-27(41-28(25)29(34)35-18-36-41)22-15-38(16-22)31(43)21-8-9-21/h3-7,10-14,17-19,21-22H,8-9,15-16H2,1-2H3,(H,37,42)(H2,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397031 (US10442810, Example 95 | US10844069, Example 95 | ...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(cc2)-c2cc(CN3CCOCC3)n3ncnc(N)c23)c(=O)n(-c2ccccc2)c1=O Show InChI InChI=1S/C31H32N8O4/c1-20(2)37-18-26(30(41)38(31(37)42)23-6-4-3-5-7-23)29(40)35-22-10-8-21(9-11-22)25-16-24(17-36-12-14-43-15-13-36)39-27(25)28(32)33-19-34-39/h3-11,16,18-20H,12-15,17H2,1-2H3,(H,35,40)(H2,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397036 (US10442810, Example 100 | US10844069, Example 100 ...) Show SMILES COc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(cc1)-c1c(Br)c(C2CCN(CC2)C(=O)C(C)C)n2ncnc(N)c12 Show InChI InChI=1S/C34H34BrN7O4/c1-20(2)33(44)40-16-13-22(14-17-40)29-28(35)26(30-31(36)37-19-38-42(29)30)21-9-11-23(12-10-21)39-32(43)27-25(46-3)15-18-41(34(27)45)24-7-5-4-6-8-24/h4-12,15,18-20,22H,13-14,16-17H2,1-3H3,(H,39,43)(H2,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397037 (US10442810, Example 101 | US10844069, Example 101 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(Br)c(C)n(-c4cncc(F)c4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C33H32BrFN8O3/c1-18(2)32(45)41-10-8-21(9-11-41)28-14-25(29-30(36)38-17-39-43(28)29)20-4-6-23(7-5-20)40-31(44)26-13-27(34)19(3)42(33(26)46)24-12-22(35)15-37-16-24/h4-7,12-18,21H,8-11H2,1-3H3,(H,40,44)(H2,36,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397042 (US10442810, Example 106 | US10844069, Example 106 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(C)c(-c4cccnc4)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C39H38N8O3/c1-24(2)38(49)45-18-15-27(16-19-45)33-21-31(35-36(40)42-23-43-47(33)35)26-11-13-29(14-12-26)44-37(48)32-20-25(3)34(28-8-7-17-41-22-28)46(39(32)50)30-9-5-4-6-10-30/h4-14,17,20-24,27H,15-16,18-19H2,1-3H3,(H,44,48)(H2,40,42,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397043 (US10442810, Example 107 | US10844069, Example 107 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(-c4cnn(C)c4)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C38H39N9O3/c1-23(2)37(49)45-16-14-26(15-17-45)33-19-31(34-35(39)40-22-42-47(33)34)25-10-12-28(13-11-25)43-36(48)32-18-30(27-20-41-44(4)21-27)24(3)46(38(32)50)29-8-6-5-7-9-29/h5-13,18-23,26H,14-17H2,1-4H3,(H,43,48)(H2,39,40,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397046 (US10442810, Example 110 | US10844069, Example 110 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(N4CCOCC4)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C38H42N8O4/c1-24(2)37(48)44-15-13-27(14-16-44)33-21-30(34-35(39)40-23-41-46(33)34)26-9-11-28(12-10-26)42-36(47)31-22-32(43-17-19-50-20-18-43)25(3)45(38(31)49)29-7-5-4-6-8-29/h4-12,21-24,27H,13-20H2,1-3H3,(H,42,47)(H2,39,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397047 (US10442810, Example 111 | US10844069, Example 111 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(C#N)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C35H34N8O3/c1-21(2)34(45)41-15-13-24(14-16-41)30-18-28(31-32(37)38-20-39-43(30)31)23-9-11-26(12-10-23)40-33(44)29-17-25(19-36)22(3)42(35(29)46)27-7-5-4-6-8-27/h4-12,17-18,20-21,24H,13-16H2,1-3H3,(H,40,44)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396994 (US10442810, Example 56 | US10844069, Example 56 | ...) Show SMILES CCN(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C33H33FN8O3/c1-3-39(2)33(45)40-17-14-22(15-18-40)28-19-27(29-30(35)36-20-37-42(28)29)21-6-10-24(11-7-21)38-31(43)26-5-4-16-41(32(26)44)25-12-8-23(34)9-13-25/h4-13,16,19-20,22H,3,14-15,17-18H2,1-2H3,(H,38,43)(H2,35,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396995 (US10442810, Example 57 | US10844069, Example 57 | ...) Show SMILES CCN(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc4C(=O)CCCc4n(-c4ccc(F)cc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C37H37FN8O4/c1-3-43(2)37(50)44-17-15-23(16-18-44)31-20-27(33-34(39)40-21-41-46(31)33)22-7-11-25(12-8-22)42-35(48)29-19-28-30(5-4-6-32(28)47)45(36(29)49)26-13-9-24(38)10-14-26/h7-14,19-21,23H,3-6,15-18H2,1-2H3,(H,42,48)(H2,39,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396996 (US10442810, Example 58 | US10844069, Example 58 | ...) Show SMILES CCN(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc4C(=O)CCCc4n(-c4ccc(F)cc4)c3=O)cc2F)c2c(N)ncnn12 Show InChI InChI=1S/C37H36F2N8O4/c1-3-44(2)37(51)45-15-13-21(14-16-45)31-19-26(33-34(40)41-20-42-47(31)33)25-12-9-23(17-29(25)39)43-35(49)28-18-27-30(5-4-6-32(27)48)46(36(28)50)24-10-7-22(38)8-11-24/h7-12,17-21H,3-6,13-16H2,1-2H3,(H,43,49)(H2,40,41,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396997 (US10442810, Example 59 | US10844069, Example 59 | ...) Show SMILES Nc1ncnn2c(cc(-c3ccc(NC(=O)c4cc5C(=O)CCCc5n(-c5ccc(F)cc5)c4=O)cc3)c12)C1CCN(CCO)CC1 Show InChI InChI=1S/C35H34FN7O4/c36-23-6-10-25(11-7-23)42-29-2-1-3-31(45)27(29)18-28(35(42)47)34(46)40-24-8-4-21(5-9-24)26-19-30(43-32(26)33(37)38-20-39-43)22-12-14-41(15-13-22)16-17-44/h4-11,18-20,22,44H,1-3,12-17H2,(H,40,46)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397005 (US10442810, Example 67 | US10844069, Example 67 | ...) Show SMILES CCn1cc(C(=O)Nc2ccc(cc2)-c2cc(C3CCN(CC3)C(=O)N(C)C)n3ncnc(N)c23)c(=O)n(-c2ccc(F)cc2)c1=O Show InChI InChI=1S/C33H34FN9O4/c1-4-40-18-26(31(45)42(33(40)47)24-11-7-22(34)8-12-24)30(44)38-23-9-5-20(6-10-23)25-17-27(43-28(25)29(35)36-19-37-43)21-13-15-41(16-14-21)32(46)39(2)3/h5-12,17-19,21H,4,13-16H2,1-3H3,(H,38,44)(H2,35,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397006 (US10442810, Example 68 | US10844069, Example 68 | ...) Show SMILES CCn1cc(C(=O)Nc2ccc(cc2)-c2cc(C3CCN(CC3)C(=O)N3CCOCC3)n3ncnc(N)c23)c(=O)n(-c2ccc(F)cc2)c1=O Show InChI InChI=1S/C35H36FN9O5/c1-2-41-20-28(33(47)44(35(41)49)26-9-5-24(36)6-10-26)32(46)40-25-7-3-22(4-8-25)27-19-29(45-30(27)31(37)38-21-39-45)23-11-13-42(14-12-23)34(48)43-15-17-50-18-16-43/h3-10,19-21,23H,2,11-18H2,1H3,(H,40,46)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397007 (US10442810, Example 69 | US10844069, Example 69 | ...) Show SMILES CCN(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cn(C(C)C)c(=O)n(-c4ccccc4F)c3=O)cc2)c2c(N)ncnn12 |(3.75,-10.02,;2.27,-9.63,;1.18,-10.72,;1.57,-12.2,;-.31,-10.32,;-1.4,-11.41,;-.71,-8.83,;-2.2,-8.43,;-2.6,-6.94,;-1.51,-5.85,;-.02,-6.25,;.38,-7.74,;-1.91,-4.37,;-1,-3.12,;-1.91,-1.88,;-1.51,-.39,;-.02,.01,;.38,1.5,;-.71,2.59,;-.31,4.07,;1.18,4.47,;2.27,3.38,;1.57,5.96,;3.06,6.36,;3.46,7.85,;4.95,8.25,;6.04,7.16,;5.35,9.73,;2.37,8.94,;2.77,10.42,;.88,8.54,;-.2,9.63,;-1.69,9.23,;-2.78,10.32,;-2.38,11.8,;-.89,12.2,;.19,11.11,;1.68,11.51,;.49,7.05,;-1,6.65,;-2.2,2.19,;-2.6,.7,;-3.37,-2.35,;-4.7,-1.58,;-4.7,-.04,;-6.04,-2.35,;-6.04,-3.89,;-4.7,-4.66,;-3.37,-3.89,)| Show InChI InChI=1S/C35H38FN9O4/c1-5-41(4)34(48)42-16-14-23(15-17-42)29-18-25(30-31(37)38-20-39-45(29)30)22-10-12-24(13-11-22)40-32(46)26-19-43(21(2)3)35(49)44(33(26)47)28-9-7-6-8-27(28)36/h6-13,18-21,23H,5,14-17H2,1-4H3,(H,40,46)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397010 (US10442810, Example 72 | US10844069, Example 72 | ...) Show SMILES CCn1cc(C(=O)Nc2ccc(cc2)-c2cc(C3CCN(CC3)C(=O)N(C)C)n3ncnc(N)c23)c(=O)n(-c2cccc(F)c2)c1=O Show InChI InChI=1S/C33H34FN9O4/c1-4-40-18-26(31(45)42(33(40)47)24-7-5-6-22(34)16-24)30(44)38-23-10-8-20(9-11-23)25-17-27(43-28(25)29(35)36-19-37-43)21-12-14-41(15-13-21)32(46)39(2)3/h5-11,16-19,21H,4,12-15H2,1-3H3,(H,38,44)(H2,35,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397011 (US10442810, Example 73 | US10844069, Example 73 | ...) Show SMILES CCn1cc(C(=O)Nc2ccc(cc2)-c2cc(C3CCN(CC3)C(=O)C(C)C)n3ncnc(N)c23)c(=O)n(-c2cccc(F)c2)c1=O Show InChI InChI=1S/C34H35FN8O4/c1-4-40-18-27(33(46)42(34(40)47)25-7-5-6-23(35)16-25)31(44)39-24-10-8-21(9-11-24)26-17-28(43-29(26)30(36)37-19-38-43)22-12-14-41(15-13-22)32(45)20(2)3/h5-11,16-20,22H,4,12-15H2,1-3H3,(H,39,44)(H2,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397014 (US10442810, Example 76 | US10844069, Example 76 | ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cn(C(C)C)c(=O)n(-c4cc(F)ccc4F)c3=O)cc2)c2c(N)ncnn12 |(2.27,-10.37,;1.18,-11.46,;1.57,-12.95,;-.31,-11.06,;-1.4,-12.15,;-.71,-9.57,;-2.2,-9.17,;-2.6,-7.69,;-1.51,-6.6,;-.02,-7,;.38,-8.48,;-1.91,-5.11,;-1,-3.86,;-1.91,-2.62,;-1.51,-1.13,;-.02,-.73,;.38,.75,;-.71,1.84,;-.31,3.33,;1.18,3.73,;2.27,2.64,;1.57,5.22,;3.06,5.62,;3.46,7.1,;4.95,7.5,;5.35,8.99,;6.04,6.41,;2.37,8.19,;2.77,9.68,;.88,7.79,;-.2,8.88,;.19,10.37,;-.89,11.46,;-.5,12.95,;-2.38,11.06,;-2.78,9.57,;-1.69,8.48,;-2.09,7,;.49,6.31,;-1,5.91,;-2.2,1.45,;-2.6,-.04,;-3.37,-3.09,;-4.7,-2.32,;-4.7,-.78,;-6.04,-3.09,;-6.04,-4.63,;-4.7,-5.4,;-3.37,-4.63,)| Show InChI InChI=1S/C35H36F2N8O4/c1-19(2)33(47)42-13-11-22(12-14-42)28-16-25(30-31(38)39-18-40-45(28)30)21-5-8-24(9-6-21)41-32(46)26-17-43(20(3)4)35(49)44(34(26)48)29-15-23(36)7-10-27(29)37/h5-10,15-20,22H,11-14H2,1-4H3,(H,41,46)(H2,38,39,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397015 (US10442810, Example 77 | US10844069, Example 77 | ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cn(C(C)C)c(=O)n(-c4ccccc4)c3=O)cc2C)c2c(N)ncnn12 Show InChI InChI=1S/C36H40N8O4/c1-21(2)34(46)41-15-13-24(14-16-41)30-18-28(31-32(37)38-20-39-44(30)31)27-12-11-25(17-23(27)5)40-33(45)29-19-42(22(3)4)36(48)43(35(29)47)26-9-7-6-8-10-26/h6-12,17-22,24H,13-16H2,1-5H3,(H,40,45)(H2,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397018 (US10442810, Example 80 | US10844069, Example 80 | ...) Show SMILES CC(O)Cn1cc(C(=O)Nc2ccc(cc2)-c2cc(C3CCN(CC3)C(=O)C3CC3)n3ncnc(N)c23)c(=O)n(-c2ccccc2)c1=O Show InChI InChI=1S/C35H36N8O5/c1-21(44)18-41-19-28(34(47)42(35(41)48)26-5-3-2-4-6-26)32(45)39-25-11-9-22(10-12-25)27-17-29(43-30(27)31(36)37-20-38-43)23-13-15-40(16-14-23)33(46)24-7-8-24/h2-6,9-12,17,19-21,23-24,44H,7-8,13-16,18H2,1H3,(H,39,45)(H2,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397022 (US10442810, Example 84 | US10844069, Example 84 | ...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(cc2)-c2cc(-c3c(C)nn(C)c3C)n3ncnc(N)c23)c(=O)n(-c2cccc(F)c2)c1=O |(6.04,5.15,;4.95,6.24,;5.35,7.73,;3.46,5.84,;3.06,4.35,;1.57,3.96,;1.18,2.47,;2.27,1.38,;-.31,2.07,;-.71,.58,;.38,-.51,;-.02,-1.99,;-1.51,-2.39,;-2.6,-1.3,;-2.2,.18,;-1.91,-3.88,;-1,-5.13,;-1.91,-6.37,;-1.51,-7.86,;-.04,-8.34,;1.29,-7.57,;-.04,-9.88,;-1.51,-10.35,;-2.28,-11.69,;-2.41,-9.11,;-3.95,-9.11,;-3.37,-5.9,;-4.7,-6.67,;-6.04,-5.9,;-6.04,-4.36,;-4.7,-3.59,;-4.7,-2.05,;-3.37,-4.36,;.49,5.04,;-1,4.65,;.88,6.53,;-.2,7.62,;-1.69,7.22,;-2.78,8.31,;-2.38,9.8,;-.89,10.2,;-.5,11.69,;.19,9.11,;2.37,6.93,;2.77,8.42,)| Show InChI InChI=1S/C32H30FN9O3/c1-17(2)40-15-25(31(44)41(32(40)45)23-8-6-7-21(33)13-23)30(43)37-22-11-9-20(10-12-22)24-14-26(27-18(3)38-39(5)19(27)4)42-28(24)29(34)35-16-36-42/h6-17H,1-5H3,(H,37,43)(H2,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397023 (US10442810, Example 85 | US10844069, Example 85 | ...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(cc2)-c2cc(-c3cnc(cc3C)C(=O)N(C)C)n3ncnc(N)c23)c(=O)n(-c2ccccc2)c1=O Show InChI InChI=1S/C35H33N9O4/c1-20(2)42-18-27(33(46)43(35(42)48)24-9-7-6-8-10-24)32(45)40-23-13-11-22(12-14-23)25-16-29(44-30(25)31(36)38-19-39-44)26-17-37-28(15-21(26)3)34(47)41(4)5/h6-20H,1-5H3,(H,40,45)(H2,36,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397024 (US10442810, Example 86 | US10844069, Example 86 | ...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(cc2)-c2cc(C(=O)N(C)C)n3ncnc(N)c23)c(=O)n(-c2cccc(F)c2)c1=O Show InChI InChI=1S/C29H27FN8O4/c1-16(2)36-14-22(27(40)37(29(36)42)20-7-5-6-18(30)12-20)26(39)34-19-10-8-17(9-11-19)21-13-23(28(41)35(3)4)38-24(21)25(31)32-15-33-38/h5-16H,1-4H3,(H,34,39)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397025 (US10442810, Example 87 | US10844069, Example 87 | ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cn(C(C)C)c(=O)n(-c4cnn(C)c4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C33H38N10O4/c1-19(2)31(45)40-12-10-22(11-13-40)27-14-25(28-29(34)35-18-37-43(27)28)21-6-8-23(9-7-21)38-30(44)26-17-41(20(3)4)33(47)42(32(26)46)24-15-36-39(5)16-24/h6-9,14-20,22H,10-13H2,1-5H3,(H,38,44)(H2,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM596414 (US11591338, Example 90) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(c([nH]1)C(\N)=N/C=N)-c1ccc(NC(=O)c2cn(C(C)C)c(=O)n(C3CCCCC3)c2=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM396942 (US10442810, Example 4 | US10844069, Example 4 | US...) Show SMILES CC[C@H](CO)n1cccc(C(=O)Nc2ccc(cc2)-c2cc(CC)n3ncnc(N)c23)c1=O |r| Show InChI InChI=1S/C24H26N6O3/c1-3-17-12-20(21-22(25)26-14-27-30(17)21)15-7-9-16(10-8-15)28-23(32)19-6-5-11-29(24(19)33)18(4-2)13-31/h5-12,14,18,31H,3-4,13H2,1-2H3,(H,28,32)(H2,25,26,27)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM396942 (US10442810, Example 4 | US10844069, Example 4 | US...) Show SMILES CC[C@H](CO)n1cccc(C(=O)Nc2ccc(cc2)-c2cc(CC)n3ncnc(N)c23)c1=O |r| Show InChI InChI=1S/C24H26N6O3/c1-3-17-12-20(21-22(25)26-14-27-30(17)21)15-7-9-16(10-8-15)28-23(32)19-6-5-11-29(24(19)33)18(4-2)13-31/h5-12,14,18,31H,3-4,13H2,1-2H3,(H,28,32)(H2,25,26,27)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396942 (US10442810, Example 4 | US10844069, Example 4 | US...) Show SMILES CC[C@H](CO)n1cccc(C(=O)Nc2ccc(cc2)-c2cc(CC)n3ncnc(N)c23)c1=O |r| Show InChI InChI=1S/C24H26N6O3/c1-3-17-12-20(21-22(25)26-14-27-30(17)21)15-7-9-16(10-8-15)28-23(32)19-6-5-11-29(24(19)33)18(4-2)13-31/h5-12,14,18,31H,3-4,13H2,1-2H3,(H,28,32)(H2,25,26,27)/t18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM396943 (US10442810, Example 5 | US10844069, Example 5 | US...) Show SMILES CCc1cc(-c2ccc(NC(=O)c3cccn(Cc4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C27H24N6O2/c1-2-21-15-23(24-25(28)29-17-30-33(21)24)19-10-12-20(13-11-19)31-26(34)22-9-6-14-32(27(22)35)16-18-7-4-3-5-8-18/h3-15,17H,2,16H2,1H3,(H,31,34)(H2,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM396943 (US10442810, Example 5 | US10844069, Example 5 | US...) Show SMILES CCc1cc(-c2ccc(NC(=O)c3cccn(Cc4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C27H24N6O2/c1-2-21-15-23(24-25(28)29-17-30-33(21)24)19-10-12-20(13-11-19)31-26(34)22-9-6-14-32(27(22)35)16-18-7-4-3-5-8-18/h3-15,17H,2,16H2,1H3,(H,31,34)(H2,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396943 (US10442810, Example 5 | US10844069, Example 5 | US...) Show SMILES CCc1cc(-c2ccc(NC(=O)c3cccn(Cc4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C27H24N6O2/c1-2-21-15-23(24-25(28)29-17-30-33(21)24)19-10-12-20(13-11-19)31-26(34)22-9-6-14-32(27(22)35)16-18-7-4-3-5-8-18/h3-15,17H,2,16H2,1H3,(H,31,34)(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM596333 (US11591338, Example 7) Show SMILES Nc1ncnn2c(cc(-c3ccc(NC(=O)c4cccn(-c5ccccc5)c4=O)cc3)c12)[C@H]1CCC(O)CC1 |r,wU:32.36,(-6.21,-1.14,;-6.61,-2.63,;-8.07,-3.1,;-8.39,-4.61,;-7.25,-5.64,;-5.78,-5.16,;-4.45,-5.93,;-3.3,-4.9,;-3.93,-3.49,;-3.16,-2.16,;-1.62,-2.16,;-.85,-.83,;-1.62,.51,;-.85,1.84,;.69,1.84,;1.46,.51,;1.46,3.17,;.69,4.51,;1.46,5.84,;3,5.84,;3.77,4.51,;5.31,4.51,;6.08,3.17,;7.62,3.17,;8.39,4.51,;7.62,5.84,;6.08,5.84,;3,3.17,;3.77,1.84,;-3.16,.51,;-3.93,-.83,;-5.46,-3.66,;-4.05,-7.42,;-2.54,-7.74,;-2.07,-9.2,;-3.1,-10.35,;-2.62,-11.81,;-4.6,-10.03,;-5.08,-8.56,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396948 (US10442810, Example 10 | US10844069, Example 10 | ...) Show SMILES Cc1cc(-c2ccc(NC(=O)c3cccn(-c4ccccc4)c3=O)cc2F)c2c(N)ncnn12 Show InChI InChI=1S/C25H19FN6O2/c1-15-12-20(22-23(27)28-14-29-32(15)22)18-10-9-16(13-21(18)26)30-24(33)19-8-5-11-31(25(19)34)17-6-3-2-4-7-17/h2-14H,1H3,(H,30,33)(H2,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396949 (US10442810, Example 11 | US10844069, Example 11 | ...) Show SMILES Cc1cc(-c2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c2c(N)ncnn12 Show InChI InChI=1S/C25H18F2N6O2/c1-14-11-20(22-23(28)29-13-30-33(14)22)18-9-6-16(12-21(18)27)31-24(34)19-3-2-10-32(25(19)35)17-7-4-15(26)5-8-17/h2-13H,1H3,(H,31,34)(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396950 (US10442810, Example 12 | US10844069, Example 12 | ...) Show SMILES CCc1cc(-c2ccc(NC(=O)c3cccn(-c4ccccc4)c3=O)cc2F)c2c(N)ncnn12 Show InChI InChI=1S/C26H21FN6O2/c1-2-17-14-21(23-24(28)29-15-30-33(17)23)19-11-10-16(13-22(19)27)31-25(34)20-9-6-12-32(26(20)35)18-7-4-3-5-8-18/h3-15H,2H2,1H3,(H,31,34)(H2,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396951 (US10442810, Example 13 | US10844069, Example 13 | ...) Show SMILES Nc1ncnn2c(cc(-c3ccc(NC(=O)c4cccn(-c5ccccc5)c4=O)cc3)c12)C1CCOCC1 Show InChI InChI=1S/C29H26N6O3/c30-27-26-24(17-25(35(26)32-18-31-27)20-12-15-38-16-13-20)19-8-10-21(11-9-19)33-28(36)23-7-4-14-34(29(23)37)22-5-2-1-3-6-22/h1-11,14,17-18,20H,12-13,15-16H2,(H,33,36)(H2,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396958 (US10442810, Example 20 | US10844069, Example 20 | ...) Show SMILES CN1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cccn(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C30H29N7O2/c1-35-16-13-21(14-17-35)26-18-25(27-28(31)32-19-33-37(26)27)20-9-11-22(12-10-20)34-29(38)24-8-5-15-36(30(24)39)23-6-3-2-4-7-23/h2-12,15,18-19,21H,13-14,16-17H2,1H3,(H,34,38)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396966 (N-{4-[4-Amino-7-(cis-4-cyanocyclohexyl)pyrrolo[2,1...) Show SMILES Nc1ncnn2c(cc(-c3ccc(NC(=O)c4cccn(-c5ccccc5)c4=O)cc3)c12)[C@@H]1CC[C@@H](CC1)C#N |r,wU:32.36,35.43,(-5.98,13.04,;-6.45,11.58,;-7.96,11.26,;-8.44,9.79,;-7.41,8.65,;-5.9,8.97,;-4.65,8.06,;-3.41,8.97,;-3.88,10.43,;-3.11,11.76,;-1.57,11.76,;-.8,13.1,;-1.57,14.43,;-.8,15.77,;.74,15.77,;1.51,14.43,;1.51,17.1,;.74,18.43,;1.51,19.77,;3.05,19.77,;3.82,18.43,;5.36,18.43,;6.13,17.1,;7.67,17.1,;8.44,18.43,;7.67,19.77,;6.13,19.77,;3.05,17.1,;3.82,15.77,;-3.11,14.43,;-3.88,13.1,;-5.42,10.43,;-4.65,6.52,;-5.99,5.75,;-5.99,4.21,;-4.65,3.44,;-3.32,4.21,;-3.32,5.75,;-4.65,1.9,;-4.65,.36,)| Show InChI InChI=1S/C31H27N7O2/c32-18-20-8-10-22(11-9-20)27-17-26(28-29(33)34-19-35-38(27)28)21-12-14-23(15-13-21)36-30(39)25-7-4-16-37(31(25)40)24-5-2-1-3-6-24/h1-7,12-17,19-20,22H,8-11H2,(H,36,39)(H2,33,34,35)/t20-,22+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396974 (US10442810, Example 36 | US10844069, Example 36 | ...) Show SMILES COC(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cccn(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C31H29N7O4/c1-42-31(41)36-16-13-21(14-17-36)26-18-25(27-28(32)33-19-34-38(26)27)20-9-11-22(12-10-20)35-29(39)24-8-5-15-37(30(24)40)23-6-3-2-4-7-23/h2-12,15,18-19,21H,13-14,16-17H2,1H3,(H,35,39)(H2,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396978 (US10442810, Example 40 | US10844069, Example 40 | ...) Show SMILES CS(=O)(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cccn(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C30H29N7O4S/c1-42(40,41)35-16-13-21(14-17-35)26-18-25(27-28(31)32-19-33-37(26)27)20-9-11-22(12-10-20)34-29(38)24-8-5-15-36(30(24)39)23-6-3-2-4-7-23/h2-12,15,18-19,21H,13-14,16-17H2,1H3,(H,34,38)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM396982 (US10442810, Example 44 | US10844069, Example 44 | ...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cccn(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C32H32N8O3/c1-37(2)32(43)38-17-14-22(15-18-38)27-19-26(28-29(33)34-20-35-40(27)28)21-10-12-23(13-11-21)36-30(41)25-9-6-16-39(31(25)42)24-7-4-3-5-8-24/h3-13,16,19-20,22H,14-15,17-18H2,1-2H3,(H,36,41)(H2,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397048 (US10442810, Example 111a | US10844069, Example 111...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(C(N)=O)c(C)n(-c4ccccc4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C35H36N8O4/c1-20(2)34(46)41-15-13-23(14-16-41)29-18-27(30-31(36)38-19-39-43(29)30)22-9-11-24(12-10-22)40-33(45)28-17-26(32(37)44)21(3)42(35(28)47)25-7-5-4-6-8-25/h4-12,17-20,23H,13-16H2,1-3H3,(H2,37,44)(H,40,45)(H2,36,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397052 (US10442810, Example 115 | US10844069, Example 115 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc4C(=O)C(C)(C)CCc4n(-c4cncc(F)c4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C38H39FN8O4/c1-21(2)36(50)45-13-10-23(11-14-45)31-17-27(32-34(40)42-20-43-47(31)32)22-5-7-25(8-6-22)44-35(49)29-16-28-30(9-12-38(3,4)33(28)48)46(37(29)51)26-15-24(39)18-41-19-26/h5-8,15-21,23H,9-14H2,1-4H3,(H,44,49)(H2,40,42,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397054 (US10442810, Example 117 | US10844069, Example 117 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(nn(-c4ccccc4)c3=O)C3CC3)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C35H36N8O3/c1-21(2)34(45)41-16-14-24(15-17-41)30-19-27(31-32(36)37-20-38-43(30)31)22-10-12-25(13-11-22)39-33(44)28-18-29(23-8-9-23)40-42(35(28)46)26-6-4-3-5-7-26/h3-7,10-13,18-21,23-24H,8-9,14-17H2,1-2H3,(H,39,44)(H2,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397055 (US10442810, Example 118 | US10844069, Example 118 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(Br)c(C)n(-c4ccccn4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C33H33BrN8O3/c1-19(2)32(44)40-14-11-22(12-15-40)27-17-24(29-30(35)37-18-38-42(27)29)21-7-9-23(10-8-21)39-31(43)25-16-26(34)20(3)41(33(25)45)28-6-4-5-13-36-28/h4-10,13,16-19,22H,11-12,14-15H2,1-3H3,(H,39,43)(H2,35,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397056 (US10442810, Example 119 | US10844069, Example 119 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cn(C4CC4)c(C)c(-c4ncco4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C34H36N8O4/c1-19(2)34(45)40-13-10-22(11-14-40)27-16-25(29-31(35)37-18-38-42(27)29)21-4-6-23(7-5-21)39-32(44)26-17-41(24-8-9-24)20(3)28(30(26)43)33-36-12-15-46-33/h4-7,12,15-19,22,24H,8-11,13-14H2,1-3H3,(H,39,44)(H2,35,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397057 (US10442810, Example 120 | US10844069, Example 120 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(cn(-c4ccccc4)c3=O)C#C[C@H](C)O)cc2)c2c(N)ncnn12 |r| Show InChI InChI=1S/C37H37N7O4/c1-23(2)36(47)42-17-15-27(16-18-42)32-20-30(33-34(38)39-22-40-44(32)33)26-11-13-28(14-12-26)41-35(46)31-19-25(10-9-24(3)45)21-43(37(31)48)29-7-5-4-6-8-29/h4-8,11-14,19-24,27,45H,15-18H2,1-3H3,(H,41,46)(H2,38,39,40)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397058 (US10442810, Example 121 | US10844069, Example 121 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(C)c(C)n(-c4cncc(F)c4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C34H35FN8O3/c1-19(2)33(45)41-11-9-23(10-12-41)29-15-27(30-31(36)38-18-39-43(29)30)22-5-7-25(8-6-22)40-32(44)28-13-20(3)21(4)42(34(28)46)26-14-24(35)16-37-17-26/h5-8,13-19,23H,9-12H2,1-4H3,(H,40,44)(H2,36,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM397059 (US10442810, Example 122 | US10844069, Example 122 ...) Show SMILES CC(C)C(=O)N1CCC(CC1)c1cc(-c2ccc(NC(=O)c3cc(CC#N)c(C)n(-c4ccccn4)c3=O)cc2)c2c(N)ncnn12 Show InChI InChI=1S/C35H35N9O3/c1-21(2)34(46)42-16-12-24(13-17-42)29-19-27(31-32(37)39-20-40-44(29)31)23-7-9-26(10-8-23)41-33(45)28-18-25(11-14-36)22(3)43(35(28)47)30-6-4-5-15-38-30/h4-10,15,18-21,24H,11-13,16-17H2,1-3H3,(H,41,45)(H2,37,39,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The kinase assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.1 ul test compounds dissolved in DMSO were ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MW2N2P
					More data for this Ligand-Target Pair

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