Found 19 hits Enz. Inhib. hit(s) with all data for entry = 11214 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600774
(US11633395, Example 18)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2ncc(F)n2c1)c1ccc(F)c(C)c1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600771
(US11633395, Example 15)Show SMILES CCc1cnc2ccc(cn12)-c1cnn2[C@@H](C)CN(C(=O)c12)c1ccc(cc1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600769
(US11633395, Example 13)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2ncc(F)n2c1)c1ccc(cc1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600770
(US11633395, Example 14)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2ncc(C)n2c1)c1ccc(cc1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600758
(US11633395, Example 2)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1cn2ccnc2cn1)c1ccc(cc1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600763
(US11633395, Example 7)Show SMILES C[C@H]1CN(c2ccc(Cl)s2)C(=O)c2c(cnn12)-c1ccc2nccn2c1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600772
(US11633395, Example 16)Show SMILES CCCc1cnc2ccc(cn12)-c1cnn2[C@@H](C)CN(C(=O)c12)c1ccc(cc1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600775
(US11633395, Example 19)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2ncc(C)n2c1)c1ccc(F)c(C)c1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600768
(US11633395, Example 12)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(cn1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600773
(US11633395, Example 17)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(F)c(C)c1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600761
(US11633395, Example 5)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(Cl)c(F)c1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600757
(US11633395, Example 1)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(cc1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600764
(US11633395, Example 8)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc2OC(F)(F)Oc2c1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600759
(US11633395, Example 3)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(F)c(Cl)c1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600762
(US11633395, Example 6)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(Cl)cc1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600760
(US11633395, Example 4)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(cc1)C(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600765
((7S)-5-[4-(difluoromethoxy)phenyl]-3-(imidazo[1,2-...)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nccn2c1)c1ccc(OC(F)F)cc1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600767
(US11633395, Example 11)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2ncc(N)n2c1)c1ccc(cc1)C(F)(F)F |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM600766
((7S)-5-[4-(trifluoromethyl)phenyl]-3-(2-aminoimida...)Show SMILES C[C@H]1CN(C(=O)c2c(cnn12)-c1ccc2nc(N)cn2c1)c1ccc(OC(F)F)cc1 |r| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 302 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2C251CZ |
More data for this Ligand-Target Pair | |