Found 284 hits Enz. Inhib. hit(s) with all data for entry = 11803 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649356
(US20240034743, Compound 48)Show SMILES COc1cc2N(C)CCn3nncc3-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649357
(US20240034743, Compound 49)Show SMILES COc1cc2CNCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649358
(US20240034743, Compound 50)Show SMILES COc1cc2C(N)CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649358
(US20240034743, Compound 50)Show SMILES COc1cc2C(N)CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649359
(US20240034743, Compound 51)Show SMILES COc1nc2NCCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649360
(US20240034743, Compound 52)Show SMILES COc1nc2NCCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649361
(US20240034743, Compound 53 | US20240034743, Compou...)Show SMILES COc1nc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2NS(C)(=O)=O)n1)C(C)C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649361
(US20240034743, Compound 53 | US20240034743, Compou...)Show SMILES COc1nc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2NS(C)(=O)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649362
(US20240034743, Compound 54)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2NS(C)(=O)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649363
(US20240034743, Compound 55)Show SMILES COc1cc2N(C)CCn3c(C)ncc3-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649364
(US20240034743, Compound 56)Show SMILES COc1cc2N(CCc3nn(CCN(C)C)cc3-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649366
(US20240034743, Compound 58)Show SMILES COc1cc2N(C)CCc3c(cnn3C)-c2cc1Nc1nc(Nc2ccccc2P(C)(C)=O)c2sccc2n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649367
(US20240034743, Compound 59)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C1CN(C)C1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649367
(US20240034743, Compound 59)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C1CN(C)C1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649368
(US20240034743, Compound 60)Show SMILES COc1cc2N(C)CCc3c(cnn3C)-c2cc1Nc1nc(Nc2ccc3nccnc3c2P(C)(C)=O)c2cc[nH]c2n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649369
(US20240034743, Compound 61)Show SMILES COc1cc2N(C)CCc3c(cnn3C)-c2cc1Nc1nc(Nc2ccc3nccnc3c2P(C)(C)=O)c2sccc2n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649370
(US20240034743, Compound 62)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCN(C)CC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649370
(US20240034743, Compound 62)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCN(C)CC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649371
(US20240034743, Compound 63)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CN(C1)C(C)C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649371
(US20240034743, Compound 63)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CN(C1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649372
(US20240034743, Compound 64)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C1COC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649372
(US20240034743, Compound 64)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C1COC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649373
(US20240034743, Compound 65)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C1CCN(C)CC1F | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649374
(US20240034743, Compound 66A)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)[C@@H]1CCN(C)C[C@H]1F |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649375
(US20240034743, Compound 66B)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)[C@H]1CCN(C)C[C@@H]1F |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649376
(US20240034743, Compound 67)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCN(C)CC1F | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649376
(US20240034743, Compound 67)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCN(C)CC1F | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649377
(US20240034743, Compound 68)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCN(C)C[C@@H]1F |r| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649377
(US20240034743, Compound 68)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCN(C)C[C@@H]1F |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649378
(US20240034743, Compound 69)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C1CN(CCF)C1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649378
(US20240034743, Compound 69)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C1CN(CCF)C1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649379
(US20240034743, Compound 70)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CN(CC2CC2)C1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649379
(US20240034743, Compound 70)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CN(CC2CC2)C1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649380
(US20240034743, Compound 71)Show SMILES COc1cc2CNCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649381
(US20240034743, Compound 72)Show SMILES COc1cc2CN(Cc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649382
(US20240034743, Compound 73)Show SMILES COc1cc2N(CC(F)(F)F)CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649383
(US20240034743, Compound 74)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649383
(US20240034743, Compound 74)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649384
(US20240034743, Compound 75)Show SMILES COc1cc2N(CCc3c(cnn3C3CCN(C)CC3)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649385
(US20240034743, Compound 76)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=S)n1)C1CCN(C)CC1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649385
(US20240034743, Compound 76)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=S)n1)C1CCN(C)CC1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649386
(US20240034743, Compound 77A)Show SMILES COc1cc2N(CCc3c(cnn3C3COC3)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649335
(US20240034743, Compound 27 | US20240034743, Compou...)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| MCE
PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649389
(US20240034743, Compound 79)Show SMILES COc1nc2N(C)CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccccc2P(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649390
(US20240034743, Compound 80)Show SMILES COc1nc2N(C)CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2NP(C)(C)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649391
(US20240034743, Compound 81)Show SMILES COc1nc2NCCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2NS(C)(=O)=O)n1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649393
(US20240034743, Compound 83)Show SMILES COc1nc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2cccnc2NP(C)(C)=O)n1)C(C)C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649394
(US20240034743, Compound 84)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCCN(C)C1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [L858R,T790M,C797S]
(Homo sapiens (Human)) | BDBM649394
(US20240034743, Compound 84)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C1CCCN(C)C1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM649395
(US20240034743, Compound 85)Show SMILES COc1cc2N(CCc3c(cnn3C)-c2cc1Nc1ncc(C)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)C(C)C | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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