Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333637 (1-(4-chloro- 3- (trifluoromethyl) phenyl)- 3-(3-(6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333638 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333638 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333638 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333639 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333639 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333640 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333640 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333640 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333641 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333641 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333641 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333642 (1-[5-(1,3- difluoro-2- methylpropan- 2- yl)isoxazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333642 (1-[5-(1,3- difluoro-2- methylpropan- 2- yl)isoxazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333642 (1-[5-(1,3- difluoro-2- methylpropan- 2- yl)isoxazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333643 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333643 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333643 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333644 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333644 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333644 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333645 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333645 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333645 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333646 (US9730937, Example 195 | ethyl 2-(3- tert-butyl-5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333646 (US9730937, Example 195 | ethyl 2-(3- tert-butyl-5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333646 (US9730937, Example 195 | ethyl 2-(3- tert-butyl-5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333647 (1-[3-(1,3- difluoro-2- methylpropan- 2-yl)-1- phen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333647 (1-[3-(1,3- difluoro-2- methylpropan- 2-yl)-1- phen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333647 (1-[3-(1,3- difluoro-2- methylpropan- 2-yl)-1- phen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333648 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333648 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333648 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333649 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333649 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333649 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333649 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333649 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333649 (1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333651 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333651 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333651 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333652 (1-(5- cyclopentyl- isoxazol- 3-yl)- 3-(3-(6,7- dim...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333652 (1-(5- cyclopentyl- isoxazol- 3-yl)- 3-(3-(6,7- dim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333652 (1-(5- cyclopentyl- isoxazol- 3-yl)- 3-(3-(6,7- dim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333653 (1-(3-tert- butylisoxazol- 5-yl)-3-(3- (6-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333653 (1-(3-tert- butylisoxazol- 5-yl)-3-(3- (6-methoxy- ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 375 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human)) | BDBM333654 (1-(3-(6- Methoxy-7- (2- methoxyethoxy) quinazolin-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM333654 (1-(3-(6- Methoxy-7- (2- methoxyethoxy) quinazolin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM333507 (1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6- methoxy-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a |
AMBIT BIOSCIENCES CORPORATION US Patent | Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.... | US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC | |||||||||||
More data for this Ligand-Target Pair |
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