Compile Data Set for Download or QSAR

Found 77 hits Enz. Inhib. hit(s) with all data for entry = 2097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM352347 (US9802939, II-62) Show SMILES CCOC(=O)[C@H]1CCCC[C@H](NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)c2cc(cc(=O)n2)-c2ccc(NC(=O)OC)cc2N1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142917 (US10487086, Example I-115 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM47108 (US10487086, Example 10 | US11136327, Example 10 | ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor XI (Homo sapiens (Human))	BDBM352344 (US9802939, II-35) Show SMILES COC(=O)Nc1ccc-2c(N[C@H](CCCC[C@H](NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cc-2ccn3)C(=O)N2CCNCC2)c1 |r| Show InChI InChI=1S/C34H37ClN10O4/c1-49-34(48)39-25-8-9-26-22-12-13-37-30(19-22)27(4-2-3-5-28(40-29(26)20-25)33(47)44-16-14-36-15-17-44)41-32(46)11-6-23-18-24(35)7-10-31(23)45-21-38-42-43-45/h6-13,18-21,27-28,36,40H,2-5,14-17H2,1H3,(H,39,48)(H,41,46)/b11-6+/t27-,28+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352315 (US9802939, I-124) Show SMILES COCCOC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142876 (US10487086, Example I-134 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3cnc(o3)[C@H](CCCCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI InChI=1S/C27H25ClN8O5/c1-40-27(39)31-18-8-9-19-21(13-18)33-24(37)5-3-2-4-20(26-29-14-23(19)41-26)32-25(38)11-6-16-12-17(28)7-10-22(16)36-15-30-34-35-36/h6-15,20H,2-5H2,1H3,(H,31,39)(H,32,38)(H,33,37)/b11-6+/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352303 (US9802939, I-80) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCC[C@@H]([C@H](CO)Nc2c1)C(=O)N1CCCC1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352302 (US9802939, I-77 | {(9R,14S)-14-[(E)-3-(5-Chloro-2-...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCC[C@H](CO)[C@H](CO)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352320 (US9802939, I-151) Show SMILES CC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](C\C=C\CCC(=O)Nc2c1)NC(=O)c1ccc2CNCCc2c1 |r,t:16| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142927 (US11136327, Example II-13 | US8940720, II-13 | US9...) Show SMILES COC(=O)Nc1ccc-2c(NC(CCCC[C@H](NC(=O)C3CC[C@H](CN)CC3)c3cc-2ccn3)C(F)(F)F)c1 |r,wU:16.16,wD:23.23,(11.38,-1.36,;10.29,-.28,;8.8,-.67,;8.41,-2.16,;7.72,.42,;6.23,.02,;5.83,-1.47,;4.34,-1.87,;3.25,-.78,;3.65,.71,;1.96,2.31,;1.96,3.85,;.62,4.62,;-.71,3.85,;-.71,2.31,;-2.05,1.54,;-2.05,,;-3.38,-.77,;-4.71,,;-4.71,1.54,;-6.05,-.77,;-6.05,-2.31,;-7.38,-3.08,;-8.71,-2.31,;-10.05,-3.08,;-10.05,-4.62,;-8.71,-.77,;-7.38,0,;-.71,-.77,;.78,-.37,;1.86,-1.46,;1.47,-2.95,;-.02,-3.35,;-1.11,-2.26,;3.29,4.62,;4.62,3.85,;3.29,6.16,;4.62,5.39,;5.14,1.11,)| Show InChI InChI=1S/C28H36F3N5O3/c1-39-27(38)34-20-10-11-21-19-12-13-33-24(14-19)22(36-26(37)18-8-6-17(16-32)7-9-18)4-2-3-5-25(28(29,30)31)35-23(21)15-20/h10-15,17-18,22,25,35H,2-9,16,32H2,1H3,(H,34,38)(H,36,37)/t17-,18?,22-,25?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142896 (US10487086, Example 61 | US8940720, 61 | US9802939...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCC(C)CCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142864 (US10487086, Example 90 | US11136327, Example 90 | ...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CC\C=C\C[C@H](NC(=O)[C@H]3CC[C@H](CN)CC3)c3cc-2ccn3)c1 |r,wU:22.21,18.18,wD:25.25,t:15,(11.34,.5,;10,1.27,;8.67,.5,;8.67,-1.04,;7.34,1.27,;6,.5,;6,-1.04,;4.67,-1.81,;3.33,-1.04,;3.33,.5,;2,1.27,;2,2.81,;3.45,3.34,;.91,3.9,;-.62,4.12,;-1.71,3.03,;-1.31,1.54,;-2.4,.45,;-2,-1.04,;-3.33,-1.81,;-4.67,-1.04,;-4.67,.5,;-6,-1.81,;-6,-3.35,;-7.34,-4.12,;-8.67,-3.35,;-10,-4.12,;-11.34,-3.35,;-8.67,-1.81,;-7.34,-1.04,;-.67,-1.81,;.67,-1.04,;2,-1.81,;2,-3.35,;.67,-4.12,;-.67,-3.35,;4.67,1.27,)| Show InChI InChI=1S/C28H35N5O4/c1-37-28(36)31-21-11-12-22-20-13-14-30-25(15-20)23(5-3-2-4-6-26(34)32-24(22)16-21)33-27(35)19-9-7-18(17-29)8-10-19/h2-3,11-16,18-19,23H,4-10,17,29H2,1H3,(H,31,36)(H,32,34)(H,33,35)/b3-2+/t18-,19-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142865 (US10487086, Example 93 | US11136327, Example 93 | ...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CC\C=C\CC(NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cccc-2c3)c1 |t:15| Show InChI InChI=1S/C31H28ClN7O4/c1-43-31(42)34-24-12-13-25-20-6-5-7-21(16-20)26(8-3-2-4-9-29(40)36-27(25)18-24)35-30(41)15-10-22-17-23(32)11-14-28(22)39-19-33-37-38-39/h2-3,5-7,10-19,26H,4,8-9H2,1H3,(H,34,42)(H,35,41)(H,36,40)/b3-2+,15-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142866 (US10487086, Example 121 | US11136327, Example 121 ...) Show SMILES Clc1[nH]c2nc1-c1ccccc1NC(=O)OC\C=C\C[C@@H]2NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,t:19| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142890 (US10487086, Example II-3 | US11136327, Example II-...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CC\C=C\C[C@H](NC(=O)c3ccc(cc3)C(N)=N)c3cc-2ccn3)c1 |r,t:15| Show InChI InChI=1S/C28H28N6O4/c1-38-28(37)32-20-11-12-21-19-13-14-31-24(15-19)22(5-3-2-4-6-25(35)33-23(21)16-20)34-27(36)18-9-7-17(8-10-18)26(29)30/h2-3,7-16,22H,4-6H2,1H3,(H3,29,30)(H,32,37)(H,33,35)(H,34,36)/b3-2+/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352337 (US9802939, I-311) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](C\C=C\CC(=O)Nc2c1)NC(=O)\C=C\c1c(F)c(Cl)ccc1C(F)(F)F |r,t:18| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352288 (US9802939, I-4) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\CC(=O)Nc2c1)NC(=O)c1ccc(cc1)C(N)=N |t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352289 (US9802939, I-5) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\CC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1ccnn1 |t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142885 (US10487086, Example I-278 | US11136327, Example I-...) Show SMILES COCCOC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCC[C@@H](Nc2c1)C(=O)OC)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352295 (US9802939, I-21) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\CC(=O)Nc2c1)NC(=O)c1c(F)cc2n(C)cnc2c1F |t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352297 (US9802939, I-59) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\C(C)C(=O)Nc2c1)NC(=O)c1c(F)cc2n(C)ccc2c1F |t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142924 (US10487086, Example I-251 | US11136327, Example I-...) Show SMILES CCOC(=O)[C@H]1CCCC[C@H](NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)c2nc(c([nH]2)C#N)-c2ccc(NC(=O)OC)cc2N1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142880 (US10487086, Example I-227 | US11136327, Example I-...) Show SMILES Fc1ccc2NC(=O)CC\C=C\C[C@H](NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3nc(c(Cl)[nH]3)-c2c1 |r,t:10| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142860 (US10487086, Example 11 | US11136327, Example 11 | ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352296 (US9802939, I-57) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\C(C)C(=O)Nc2c1)NC(=O)c1c(F)cc2n(C)ncc2c1F |t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352336 (US9802939, I-309) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](C\C=C\CC(=O)Nc2c1)NC(=O)\C=C\c1cccc(Cl)c1 |r,t:18| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352331 (US9802939, I-268) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCCCNc2c1)NC(=O)\C=C\c1cc(C)ccc1N1CNN=N1 |c:44| Show InChI InChI=1S/C29H32N10O3/c1-18-7-11-25(39-17-32-37-38-39)19(14-18)8-12-26(40)34-22-6-4-3-5-13-31-23-15-20(33-29(41)42-2)9-10-21(23)27-24(16-30)35-28(22)36-27/h7-12,14-15,22,31H,3-6,13,17H2,1-2H3,(H,32,38)(H,33,41)(H,34,40)(H,35,36)/b12-8+/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352335 (US9802939, I-299) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C(=O)N(C)C)[C@H](CCCCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142870 (US10487086, Example 138 | US11136327, Example 138 ...) Show SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2CCCCC(=O)Nc3cnccc3-c3ccnc2c3)c1)-n1cnnn1 |r| Show InChI InChI=1S/C26H23ClN8O2/c27-19-6-7-24(35-16-30-33-34-35)18(13-19)5-8-26(37)31-21-3-1-2-4-25(36)32-23-15-28-11-10-20(23)17-9-12-29-22(21)14-17/h5-16,21H,1-4H2,(H,31,37)(H,32,36)/b8-5+/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142894 (US10487086, Example II-58 | US8940720, II-58 | US9...) Show SMILES COC(=O)Nc1ccc-2c(N[C@H](CCCC[C@H](NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cncc-2c3)C(=O)NCc2ccccn2)c1 |r| Show InChI InChI=1S/C36H35ClN10O4/c1-51-36(50)42-27-11-12-29-24-16-25(20-38-19-24)30(44-34(48)14-9-23-17-26(37)10-13-33(23)47-22-41-45-46-47)7-2-3-8-31(43-32(29)18-27)35(49)40-21-28-6-4-5-15-39-28/h4-6,9-20,22,30-31,43H,2-3,7-8,21H2,1H3,(H,40,49)(H,42,50)(H,44,48)/b14-9+/t30-,31+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352321 (US9802939, I-152) Show SMILES CC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](C\C=C\CCC(=O)Nc2c1)NC(=O)c1ccc2[C@H](N)CCCc2c1 |r,t:16| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142892 (US10487086, Example II-10 | US11136327, Example II...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CCCCC(NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cc-2nc(C)n3)c1 Show InChI InChI=1S/C29H28ClN9O4/c1-17-32-24-15-25(33-17)22(35-28(41)12-7-18-13-19(30)8-11-26(18)39-16-31-37-38-39)5-3-4-6-27(40)36-23-14-20(9-10-21(23)24)34-29(42)43-2/h7-16,22H,3-6H2,1-2H3,(H,34,42)(H,35,41)(H,36,40)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352308 (US9802939, I-106 | {(S)-14-[(E)-3-(5-Chloro-2-tetr...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCC\C=C\C(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,t:19| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352283 ((E)-3-(5-Chloro-2-tetrazol-1-yl-phenyl)-N—((S...) Show SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2CC=CCCC(=O)Nc3ccccc3-c3nnc2o3)c1)-n1cnnn1 |r,w:14.14| Show InChI InChI=1S/C25H21ClN8O3/c26-17-11-12-21(34-15-27-32-33-34)16(14-17)10-13-23(36)29-20-8-2-1-3-9-22(35)28-19-7-5-4-6-18(19)24-30-31-25(20)37-24/h1-2,4-7,10-15,20H,3,8-9H2,(H,28,35)(H,29,36)/b2-1?,13-10+/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142875 (US10487086, Example I-107 | US11136327, Example I-...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3F)[C@H](CCCC\C=N\c2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,t:21| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142858 (US10487086, Example 6 | US11136327, Example 6 | US...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCCCCc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142861 (US10487086, Example 19 | US11136327, Example 19 | ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](C\C=C/CS(=O)(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,c:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352334 (US9802939, I-284) Show SMILES CC(=O)c1ccc2-c3c[nH]c(n3)[C@H](CCCCC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142891 (US10487086, Example II-4 | US11136327, Example II-...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)CCCC[C@H](NC(=O)c3c(F)cc(C)cc3F)c3cc-2ccn3)c1 |r| Show InChI InChI=1S/C27H26F2N4O4/c1-15-11-19(28)25(20(29)12-15)26(35)33-21-5-3-4-6-24(34)32-22-14-17(31-27(36)37-2)7-8-18(22)16-9-10-30-23(21)13-16/h7-14,21H,3-6H2,1-2H3,(H,31,36)(H,32,34)(H,33,35)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352330 (US9802939, I-265) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C#N)[C@H](CCCNC(=O)Nc2c1)NC(=O)\C=C\c1c(F)c(Cl)ccc1C(C)=O Show InChI InChI=1S/C28H25ClFN7O5/c1-14(38)16-7-9-19(29)24(30)17(16)8-10-23(39)34-20-4-3-11-32-27(40)36-21-12-15(33-28(41)42-2)5-6-18(21)25-22(13-31)35-26(20)37-25/h5-10,12,20H,3-4,11H2,1-2H3,(H,33,41)(H,34,39)(H,35,37)(H2,32,36,40)/b10-8+/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142871 (US10487086, Example 167 | US11136327, Example 167 ...) Show SMILES COC(=O)Nc1ccc-2c(NC(=O)C\C=C\CC(NC(=O)\C=C\c3cc(Cl)ccc3-n3cnnn3)c3cc-2nc(C)n3)c1 |t:14| Show InChI InChI=1S/C29H26ClN9O4/c1-17-32-24-15-25(33-17)22(35-28(41)12-7-18-13-19(30)8-11-26(18)39-16-31-37-38-39)5-3-4-6-27(40)36-23-14-20(9-10-21(23)24)34-29(42)43-2/h3-4,7-16,22H,5-6H2,1-2H3,(H,34,42)(H,35,41)(H,36,40)/b4-3+,12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352317 (US10487086, Example I-136 | US9802939, I-136) Show SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2CCCCCNc3cc4[nH]ncc4cc3-c3c[nH]c2n3)c1)-n1cnnn1 |r| Show InChI InChI=1S/C26H23ClN10O/c27-18-6-7-24(37-15-31-35-36-37)16(10-18)5-8-25(38)32-20-4-2-1-3-9-28-22-12-21-17(13-30-34-21)11-19(22)23-14-29-26(20)33-23/h5-8,10-15,20,28H,1-4,9H2,(H,32,38)/b8-5+,23-19-/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	183	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142869 (US10487086, Example 137 | US11136327, Example 137 ...) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CC(O)C(O)CC(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	192	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352299 ((9 S,14S)-14-[(E)-3-(5-Chloro-2-tetrazol-1-yl-phen...) Show SMILES CCOC(=O)[C@@H]1CCCC[C@H](NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)c2nc(c[nH]2)-c2ccc(NC(=O)OC)cc2N1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352291 (US9802939, I-10) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\CC(=O)Nc2c1)NC(=O)c1cn(nn1)-c1cccc(Cl)c1 |t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	217	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM142859 (US10487086, Example 9 | US11136327, Example 9 | US...) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](CCCCCOc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	249	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352300 (US9802939, I-70) Show SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C)C(C\C=C\[C@@H](C(=O)Nc2c1)C(F)(F)F)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,t:18| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352301 (US9802939, I-72) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\[C@H](C(F)F)C(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r,t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	289	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352311 (US9802939, I-114) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)[C@H](CCCC(C)C(C(N)=O)C(=O)Nc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM352292 (US9802939, I-13) Show SMILES COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\CC(=O)Nc2c1)NC(=O)c1ccc2NCCCc2c1 |t:17| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	311	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
					More data for this Ligand-Target Pair

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