Compile Data Set for Download or QSAR

Found 167 hits Enz. Inhib. hit(s) with all data for entry = 2293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360442 (US9828369, Example 14 | ethyl 3-(8-((2- phenylcycl...) Show SMILES CCOC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2cnccc12 Show InChI InChI=1S/C29H26N2O3/c1-2-34-29(33)21-10-6-9-20(15-21)23-12-11-22(27-18-30-14-13-24(23)27)17-31-28(32)26-16-25(26)19-7-4-3-5-8-19/h3-15,18,25-26H,2,16-17H2,1H3,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360342 (US9828369, Example 3 | methyl 3-(8-(((1R,2R)-2- ph...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2cnccc12 Show InChI InChI=1S/C28H24N2O3/c1-33-28(32)20-9-5-8-19(14-20)22-11-10-21(26-17-29-13-12-23(22)26)16-30-27(31)25-15-24(25)18-6-3-2-4-7-18/h2-14,17,24-25H,15-16H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	82.7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360337 (US9828369, Example 2 | methyl 3-(8-((2-(4-(trifluo...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)Cc2ccc(cc2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C27H21F3N2O3/c1-35-26(34)19-4-2-3-18(14-19)22-10-7-20(24-16-31-12-11-23(22)24)15-32-25(33)13-17-5-8-21(9-6-17)27(28,29)30/h2-12,14,16H,13,15H2,1H3,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85.6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360343 (US9828369, Example 4 | methyl 3-(8-((2-(3-methyl-1...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CC2c2nc(C)no2)c2cnccc12 Show InChI InChI=1S/C25H22N4O4/c1-14-28-24(33-29-14)21-11-20(21)23(30)27-12-17-6-7-18(19-8-9-26-13-22(17)19)15-4-3-5-16(10-15)25(31)32-2/h3-10,13,20-21H,11-12H2,1-2H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	96.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360348 (US9828369, Example 5 | methyl 3-(8-((1-(4-(trifluo...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CCN(CC2)c2ccc(cc2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C31H28F3N3O3/c1-40-30(39)22-4-2-3-21(17-22)26-10-5-23(28-19-35-14-11-27(26)28)18-36-29(38)20-12-15-37(16-13-20)25-8-6-24(7-9-25)31(32,33)34/h2-11,14,17,19-20H,12-13,15-16,18H2,1H3,(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360433 (US9828369, Example 6 | methyl 3-(8-((2-(4-phenoxyp...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)Cc2ccc(Oc3ccccc3)cc2)c2cnccc12 Show InChI InChI=1S/C32H26N2O4/c1-37-32(36)24-7-5-6-23(19-24)28-15-12-25(30-21-33-17-16-29(28)30)20-34-31(35)18-22-10-13-27(14-11-22)38-26-8-3-2-4-9-26/h2-17,19,21H,18,20H2,1H3,(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360434 (US9828369, Example 7 | methyl 3-(8-((3-(tert-butyl...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)c2cc(nn2C)C(C)(C)C)c2cnccc12 Show InChI InChI=1S/C27H28N4O3/c1-27(2,3)24-14-23(31(4)30-24)25(32)29-15-19-9-10-20(21-11-12-28-16-22(19)21)17-7-6-8-18(13-17)26(33)34-5/h6-14,16H,15H2,1-5H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360444 (N-((5-(3-ethoxyphenyl)isoquinolin- 8-yl)methyl)-2-...) Show SMILES CCOc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2cnccc12 Show InChI InChI=1S/C28H26N2O2/c1-2-32-22-10-6-9-20(15-22)23-12-11-21(27-18-29-14-13-24(23)27)17-30-28(31)26-16-25(26)19-7-4-3-5-8-19/h3-15,18,25-26H,2,16-17H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360600 (1-([1,1'-biphenyl]-3-yl)-3-((5(3- methoxyphenyl)is...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)Nc2cccc(c2)-c2ccccc2)c2cnccc12 Show InChI InChI=1S/C30H25N3O2/c1-35-26-12-6-10-23(18-26)27-14-13-24(29-20-31-16-15-28(27)29)19-32-30(34)33-25-11-5-9-22(17-25)21-7-3-2-4-8-21/h2-18,20H,19H2,1H3,(H2,32,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360585 ((R/S)-2-(6-methoxynaphthalen-2-yl)- N-((5-(3-metho...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)[C@H](C)c2ccc3cc(OC)ccc3c2)c2cnccc12 |r| Show InChI InChI=1S/C31H28N2O3/c1-20(21-7-8-23-16-27(36-3)11-9-22(23)15-21)31(34)33-18-25-10-12-28(29-13-14-32-19-30(25)29)24-5-4-6-26(17-24)35-2/h4-17,19-20H,18H2,1-3H3,(H,33,34)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360435 (US9828369, Example 8 | methyl 3-(8-((1-phenyl-5- (...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)c2cnn(c2C(F)(F)F)-c2ccccc2)c2cnccc12 Show InChI InChI=1S/C29H21F3N4O3/c1-39-28(38)19-7-5-6-18(14-19)22-11-10-20(24-16-33-13-12-23(22)24)15-34-27(37)25-17-35-36(26(25)29(30,31)32)21-8-3-2-4-9-21/h2-14,16-17H,15H2,1H3,(H,34,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360436 (US9828369, Example 9 | methyl 3-(8-((1-methyl-3-pr...) Show SMILES CCCc1cc(C(=O)NCc2ccc(-c3cccc(c3)C(=O)OC)c3ccncc23)n(C)n1 Show InChI InChI=1S/C26H26N4O3/c1-4-6-20-14-24(30(2)29-20)25(31)28-15-19-9-10-21(22-11-12-27-16-23(19)22)17-7-5-8-18(13-17)26(32)33-3/h5,7-14,16H,4,6,15H2,1-3H3,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360437 (US9828369, Example 10 | methyl 3-(8-((spiro[2.4]he...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CC22CCCC2)c2cnccc12 Show InChI InChI=1S/C26H26N2O3/c1-31-25(30)18-6-4-5-17(13-18)20-8-7-19(22-16-27-12-9-21(20)22)15-28-24(29)23-14-26(23)10-2-3-11-26/h4-9,12-13,16,23H,2-3,10-11,14-15H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360438 (8-((isoquinoline-1- carboxamido)methyl)-5-(3- (met...) Show SMILES OCC(=O)c1cccc(c1)-c1ccc(CNC(=O)c2nccc3ccccc23)c2cnccc12 Show InChI InChI=1S/C28H21N3O3/c32-17-26(33)20-6-3-5-19(14-20)22-9-8-21(25-16-29-12-11-24(22)25)15-31-28(34)27-23-7-2-1-4-18(23)10-13-30-27/h1-14,16,32H,15,17H2,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360545 (2-(4-fluorophenyl)-N-((5-(3- methoxyphenyl)isoquin...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccc(F)cc2)c2cnccc12 Show InChI InChI=1S/C27H23FN2O2/c1-32-21-4-2-3-18(13-21)22-10-7-19(26-16-29-12-11-23(22)26)15-30-27(31)25-14-24(25)17-5-8-20(28)9-6-17/h2-13,16,24-25H,14-15H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360439 (8-((isoquinoline-5- carboxamido)methyl)-5-(3- (me...) Show SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)c2cccc3cnccc23)c2cnccc12 Show InChI InChI=1S/C28H21N3O3/c1-34-28(33)19-5-2-4-18(14-19)22-9-8-21(26-17-30-13-11-24(22)26)16-31-27(32)25-7-3-6-20-15-29-12-10-23(20)25/h2-15,17H,16H2,1H3,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360586 (2-(6-methoxynaphthalen-2-yl)-N-((5- (3-methoxyphen...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccc3cc(OC)ccc3c2)c2cnccc12 Show InChI InChI=1S/C31H28N2O3/c1-20(21-7-8-23-16-27(36-3)11-9-22(23)15-21)31(34)33-18-25-10-12-28(29-13-14-32-19-30(25)29)24-5-4-6-26(17-24)35-2/h4-17,19-20H,18H2,1-3H3,(H,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360595 (1-(2,3-dichlorophenyl)-3-((5-(3,5- dimethoxyphenyl...) Show SMILES COc1cc(OC)cc(c1)-c1ccc(CNC(=O)Nc2cccc(Cl)c2Cl)c2cnccc12 Show InChI InChI=1S/C25H21Cl2N3O3/c1-32-17-10-16(11-18(12-17)33-2)19-7-6-15(21-14-28-9-8-20(19)21)13-29-25(31)30-23-5-3-4-22(26)24(23)27/h3-12,14H,13H2,1-2H3,(H2,29,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360613 (US9828369, Example 172) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2ccccc12 Show InChI InChI=1S/C28H25NO2/c1-31-22-11-7-10-20(16-22)24-15-14-21(23-12-5-6-13-25(23)24)18-29-28(30)27-17-26(27)19-8-3-2-4-9-19/h2-16,26-27H,17-18H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360582 (2-(2-fluorophenyl)-N-((5-(3- methoxyphenyl)isoquin...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccccc2F)c2cnccc12 Show InChI InChI=1S/C26H23FN2O2/c1-17(21-8-3-4-9-25(21)27)26(30)29-15-19-10-11-22(23-12-13-28-16-24(19)23)18-6-5-7-20(14-18)31-2/h3-14,16-17H,15H2,1-2H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360542 (2-(3-bromophenyl)-N-((5-(3- methoxyphenyl)isoquino...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccc(Br)cc2)c2cnccc12 Show InChI InChI=1S/C27H23BrN2O2/c1-32-21-4-2-3-18(13-21)22-10-7-19(26-16-29-12-11-23(22)26)15-30-27(31)25-14-24(25)17-5-8-20(28)9-6-17/h2-13,16,24-25H,14-15H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360543 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)sp...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2CC22CCCCC2)c2cnccc12 Show InChI InChI=1S/C26H28N2O2/c1-30-20-7-5-6-18(14-20)21-9-8-19(23-17-27-13-10-22(21)23)16-28-25(29)24-15-26(24)11-3-2-4-12-26/h5-10,13-14,17,24H,2-4,11-12,15-16H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	243	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360579 (2-(4-cyanophenyl)-N-((5-(3- methoxyphenyl)isoquino...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccc(cc2)C#N)c2cnccc12 Show InChI InChI=1S/C27H23N3O2/c1-18(20-8-6-19(15-28)7-9-20)27(31)30-16-22-10-11-24(25-12-13-29-17-26(22)25)21-4-3-5-23(14-21)32-2/h3-14,17-18H,16H2,1-2H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	256	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360573 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)bi...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C23CC(C2)C3)c2cnccc12 Show InChI InChI=1S/C23H22N2O2/c1-27-18-4-2-3-16(9-18)19-6-5-17(21-14-24-8-7-20(19)21)13-25-22(26)23-10-15(11-23)12-23/h2-9,14-15H,10-13H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360447 (N-((5-(3- (methoxymethyl)phenyl)isoquinolin- 8-yl)...) Show SMILES COCc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2cnccc12 Show InChI InChI=1S/C28H26N2O2/c1-32-18-19-6-5-9-21(14-19)23-11-10-22(27-17-29-13-12-24(23)27)16-30-28(31)26-15-25(26)20-7-3-2-4-8-20/h2-14,17,25-26H,15-16,18H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360489 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)Cc2cccc(c2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C26H21F3N2O2/c1-33-21-7-3-5-18(14-21)22-9-8-19(24-16-30-11-10-23(22)24)15-31-25(32)13-17-4-2-6-20(12-17)26(27,28)29/h2-12,14,16H,13,15H2,1H3,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	291	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360581 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccccc2)c2cnccc12 Show InChI InChI=1S/C26H24N2O2/c1-18(19-7-4-3-5-8-19)26(29)28-16-21-11-12-23(24-13-14-27-17-25(21)24)20-9-6-10-22(15-20)30-2/h3-15,17-18H,16H2,1-2H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360537 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-3...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)CCc2cnn(C)c2)c2cnccc12 Show InChI InChI=1S/C24H24N4O2/c1-28-16-17(13-27-28)6-9-24(29)26-14-19-7-8-21(22-10-11-25-15-23(19)22)18-4-3-5-20(12-18)30-2/h3-5,7-8,10-13,15-16H,6,9,14H2,1-2H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360498 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)Cc2ccccc2Oc2ccccc2)c2cnccc12 Show InChI InChI=1S/C31H26N2O3/c1-35-26-12-7-9-22(18-26)27-15-14-24(29-21-32-17-16-28(27)29)20-33-31(34)19-23-8-5-6-13-30(23)36-25-10-3-2-4-11-25/h2-18,21H,19-20H2,1H3,(H,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	306	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360484 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)Cc2ccc(cc2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C26H21F3N2O2/c1-33-21-4-2-3-18(14-21)22-10-7-19(24-16-30-12-11-23(22)24)15-31-25(32)13-17-5-8-20(9-6-17)26(27,28)29/h2-12,14,16H,13,15H2,1H3,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360588 ((R/S)-2-(2-fluoro-[1,1'-biphenyl]-4-yl)- N-((5-(3-...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)[C@H](C)c2ccc(c(F)c2)-c2ccccc2)c2cnccc12 |r| Show InChI InChI=1S/C32H27FN2O2/c1-21(23-11-14-28(31(33)18-23)22-7-4-3-5-8-22)32(36)35-19-25-12-13-27(29-15-16-34-20-30(25)29)24-9-6-10-26(17-24)37-2/h3-18,20-21H,19H2,1-2H3,(H,35,36)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360577 (2-([1,1'-biphenyl]-4-yl)-N-((5-(3- methoxyphenyl)i...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccc(cc2)-c2ccccc2)c2cnccc12 Show InChI InChI=1S/C32H28N2O2/c1-22(23-11-13-25(14-12-23)24-7-4-3-5-8-24)32(35)34-20-27-15-16-29(30-17-18-33-21-31(27)30)26-9-6-10-28(19-26)36-2/h3-19,21-22H,20H2,1-2H3,(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360569 ((R/S)-2-(3-fluoro-4- (trifluoromethyl)phenyl)-N-((...) Show SMILES CC[C@H](C(=O)NCc1ccc(-c2cccc(OC)c2)c2ccncc12)c1ccc(c(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C28H24F4N2O2/c1-3-21(18-8-10-25(26(29)14-18)28(30,31)32)27(35)34-15-19-7-9-22(23-11-12-33-16-24(19)23)17-5-4-6-20(13-17)36-2/h4-14,16,21H,3,15H2,1-2H3,(H,34,35)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	373	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360601 (1-(2,3-dichlorophenyl)-3-((5-(1- phenylyinyl)isoqu...) Show SMILES Clc1cccc(NC(=O)NCc2ccc(C(=C)c3ccccc3)c3ccncc23)c1Cl Show InChI InChI=1S/C25H19Cl2N3O/c1-16(17-6-3-2-4-7-17)19-11-10-18(21-15-28-13-12-20(19)21)14-29-25(31)30-23-9-5-8-22(26)24(23)27/h2-13,15H,1,14H2,(H2,29,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360574 (5-bromo-2-fluoro-N-((5-(3- methoxyphenyl)isoquinol...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2cc(Br)cnc2F)c2cnccc12 Show InChI InChI=1S/C23H17BrFN3O2/c1-30-17-4-2-3-14(9-17)18-6-5-15(21-13-26-8-7-19(18)21)11-28-23(29)20-10-16(24)12-27-22(20)25/h2-10,12-13H,11H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360593 (N-((5-(3-methoxyphenyl)quinolin- 8-yl)methyl)-2-(4...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)Cc2ccc(cc2)C(F)(F)F)c2ncccc12 Show InChI InChI=1S/C26H21F3N2O2/c1-33-21-5-2-4-18(15-21)22-12-9-19(25-23(22)6-3-13-30-25)16-31-24(32)14-17-7-10-20(11-8-17)26(27,28)29/h2-13,15H,14,16H2,1H3,(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	426	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360602 (1-(2,3-dichlorophenyl)-3-((5-(3- methoxypropyl)iso...) Show SMILES COCCCc1ccc(CNC(=O)Nc2cccc(Cl)c2Cl)c2cnccc12 Show InChI InChI=1S/C21H21Cl2N3O2/c1-28-11-3-4-14-7-8-15(17-13-24-10-9-16(14)17)12-25-21(27)26-19-6-2-5-18(22)20(19)23/h2,5-10,13H,3-4,11-12H2,1H3,(H2,25,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	478	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360509 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-1...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2cn(nc2-c2ccccc2)-c2ccccc2)c2cnccc12 Show InChI InChI=1S/C33H26N4O2/c1-39-27-14-8-11-24(19-27)28-16-15-25(30-21-34-18-17-29(28)30)20-35-33(38)31-22-37(26-12-6-3-7-13-26)36-32(31)23-9-4-2-5-10-23/h2-19,21-22H,20H2,1H3,(H,35,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	479	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360524 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)Cc2nnc([nH]2)-c2ccccc2)c2cnccc12 Show InChI InChI=1S/C27H23N5O2/c1-34-21-9-5-8-19(14-21)22-11-10-20(24-17-28-13-12-23(22)24)16-29-26(33)15-25-30-27(32-31-25)18-6-3-2-4-7-18/h2-14,17H,15-16H2,1H3,(H,29,33)(H,30,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	483	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360547 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2cccnc2)c2cnccc12 Show InChI InChI=1S/C26H23N3O2/c1-31-20-6-2-4-17(12-20)21-8-7-19(25-16-28-11-9-22(21)25)15-29-26(30)24-13-23(24)18-5-3-10-27-14-18/h2-12,14,16,23-24H,13,15H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	483	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360580 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccc(OC(F)(F)F)cc2)c2cnccc12 Show InChI InChI=1S/C27H23F3N2O3/c1-17(18-6-9-21(10-7-18)35-27(28,29)30)26(33)32-15-20-8-11-23(24-12-13-31-16-25(20)24)19-4-3-5-22(14-19)34-2/h3-14,16-17H,15H2,1-2H3,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	484	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360566 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-1...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2(CCC2)c2ccc(cc2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C29H25F3N2O2/c1-36-23-5-2-4-19(16-23)24-11-6-20(26-18-33-15-12-25(24)26)17-34-27(35)28(13-3-14-28)21-7-9-22(10-8-21)29(30,31)32/h2,4-12,15-16,18H,3,13-14,17H2,1H3,(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360451 ((1S,2S)-2-(4-methoxyphenyl)-N-((5- (3-methoxypheny...) Show SMILES COc1ccc(cc1)C1CC1C(=O)NCc1ccc(-c2cccc(OC)c2)c2ccncc12 Show InChI InChI=1S/C28H26N2O3/c1-32-21-9-6-18(7-10-21)25-15-26(25)28(31)30-16-20-8-11-23(24-12-13-29-17-27(20)24)19-4-3-5-22(14-19)33-2/h3-14,17,25-26H,15-16H2,1-2H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	537	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360553 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-4...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2n[nH]c(=O)c3ccccc23)c2cnccc12 Show InChI InChI=1S/C26H20N4O3/c1-33-18-6-4-5-16(13-18)19-10-9-17(23-15-27-12-11-20(19)23)14-28-26(32)24-21-7-2-3-8-22(21)25(31)30-29-24/h2-13,15H,14H2,1H3,(H,28,32)(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	544	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360502 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)Cc2cc(F)c(F)cc2F)c2cnccc12 Show InChI InChI=1S/C25H19F3N2O2/c1-32-18-4-2-3-15(9-18)19-6-5-16(21-14-29-8-7-20(19)21)13-30-25(31)11-17-10-23(27)24(28)12-22(17)26/h2-10,12,14H,11,13H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360584 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccc(cc2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C27H23F3N2O2/c1-17(18-6-9-21(10-7-18)27(28,29)30)26(33)32-15-20-8-11-23(24-12-13-31-16-25(20)24)19-4-3-5-22(14-19)34-2/h3-14,16-17H,15H2,1-2H3,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360576 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2ccnc(c2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C24H18F3N3O2/c1-32-18-4-2-3-15(11-18)19-6-5-17(21-14-28-9-8-20(19)21)13-30-23(31)16-7-10-29-22(12-16)24(25,26)27/h2-12,14H,13H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	571	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360551 ((trans)-N-((5-(3- methoxyphenyl)isoquinolin-8- yl)...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)[C@H]2CC2c2nc(C)no2)c2cnccc12 |r| Show InChI InChI=1S/C24H22N4O3/c1-14-27-24(31-28-14)21-11-20(21)23(29)26-12-16-6-7-18(19-8-9-25-13-22(16)19)15-4-3-5-17(10-15)30-2/h3-10,13,20-21H,11-12H2,1-2H3,(H,26,29)/t20-,21?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360452 ((cis)-2-(4-methoxyphenyl)-N-((5-(3- methoxyphenyl)...) Show SMILES COc1ccc(cc1)[C@@H]1C[C@@H]1C(=O)NCc1ccc(-c2cccc(OC)c2)c2ccncc12 |r| Show InChI InChI=1S/C28H26N2O3/c1-32-21-9-6-18(7-10-21)25-15-26(25)28(31)30-16-20-8-11-23(24-12-13-29-17-27(20)24)19-4-3-5-22(14-19)33-2/h3-14,17,25-26H,15-16H2,1-2H3,(H,30,31)/t25-,26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360540 (2-(4-chlorophenyl)-N-((5-(3 methoxyphenyl)isoquino...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccc(Cl)cc2)c2cnccc12 Show InChI InChI=1S/C27H23ClN2O2/c1-32-21-4-2-3-18(13-21)22-10-7-19(26-16-29-12-11-23(22)26)15-30-27(31)25-14-24(25)17-5-8-20(28)9-6-17/h2-13,16,24-25H,14-15H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	597	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair

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