Compile Data Set for Download or QSAR

Found 142 hits Enz. Inhib. hit(s) with all data for entry = 2545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370772 (US10239835, Example 00324) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccc(F)cc1 |r,w:10.11| Show InChI InChI=1S/C20H23FN2O3/c21-15-1-4-17(5-2-15)26-18-7-13-10-23(11-14(13)8-18)12-20(25)19-6-3-16(24)9-22-19/h1-6,9,13-14,18,20,24-25H,7-8,10-12H2/t13-,14+,18+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.41	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370754 (US10239835, Example 00306) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccccc1F |r,w:10.11| Show InChI InChI=1S/C21H24FNO3/c22-19-3-1-2-4-21(19)26-18-9-15-11-23(12-16(15)10-18)13-20(25)14-5-7-17(24)8-6-14/h1-8,15-16,18,20,24-25H,9-13H2/t15-,16+,18+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.44	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370814 (US10239835, Example 00365) Show SMILES [H][C@@]1(C[C@]2([H])CN(C[C@@H](O)c3ccc(O)cn3)C[C@]2([H])C1)Oc1ccccc1 |r| Show InChI InChI=1S/C20H24N2O3/c23-16-6-7-19(21-10-16)20(24)13-22-11-14-8-18(9-15(14)12-22)25-17-4-2-1-3-5-17/h1-7,10,14-15,18,20,23-24H,8-9,11-13H2/t14-,15+,18+,20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.24	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370813 (US10239835, Example 00364) Show SMILES [H][C@@]1(C[C@]2([H])CN(C[C@H](O)c3ccc(O)cn3)C[C@]2([H])C1)Oc1ccccc1 |r| Show InChI InChI=1S/C20H24N2O3/c23-16-6-7-19(21-10-16)20(24)13-22-11-14-8-18(9-15(14)12-22)25-17-4-2-1-3-5-17/h1-7,10,14-15,18,20,23-24H,8-9,11-13H2/t14-,15+,18+,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.25	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370756 (US10239835, Example 00308) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccccc1 |r,w:10.11| Show InChI InChI=1S/C20H24N2O3/c23-16-6-7-19(21-10-16)20(24)13-22-11-14-8-18(9-15(14)12-22)25-17-4-2-1-3-5-17/h1-7,10,14-15,18,20,23-24H,8-9,11-13H2/t14-,15+,18+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.72	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370745 (US10239835, Example 00297) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccccc1 |r,w:10.11| Show InChI InChI=1S/C21H25NO3/c23-18-8-6-15(7-9-18)21(24)14-22-12-16-10-20(11-17(16)13-22)25-19-4-2-1-3-5-19/h1-9,16-17,20-21,23-24H,10-14H2/t16-,17+,20+,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.96	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370743 (US10239835, Example 00295) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccccc1F |r,w:10.11| Show InChI InChI=1S/C20H23FN2O3/c21-17-3-1-2-4-20(17)26-16-7-13-10-23(11-14(13)8-16)12-19(25)18-6-5-15(24)9-22-18/h1-6,9,13-14,16,19,24-25H,7-8,10-12H2/t13-,14+,16+,19?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370781 (US10239835, Example 00333) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccc(F)cc1F |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-14-1-4-20(17(22)7-14)27-16-5-12-9-24(10-13(12)6-16)11-19(26)18-3-2-15(25)8-23-18/h1-4,7-8,12-13,16,19,25-26H,5-6,9-11H2/t12-,13+,16+,19?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.81	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370815 (US10239835, Example 00366) Show SMILES [H][C@@]1(C[C@]2([H])CN(C[C@H](O)c3ccc(O)cn3)C[C@]2([H])C1)Oc1ccccc1F |r| Show InChI InChI=1S/C20H23FN2O3/c21-17-3-1-2-4-20(17)26-16-7-13-10-23(11-14(13)8-16)12-19(25)18-6-5-15(24)9-22-18/h1-6,9,13-14,16,19,24-25H,7-8,10-12H2/t13-,14+,16+,19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370816 (US10239835, Example 00367) Show SMILES [H][C@@]1(C[C@]2([H])CN(C[C@@H](O)c3ccc(O)cn3)C[C@]2([H])C1)Oc1ccccc1F |r| Show InChI InChI=1S/C20H23FN2O3/c21-17-3-1-2-4-20(17)26-16-7-13-10-23(11-14(13)8-16)12-19(25)18-6-5-15(24)9-22-18/h1-6,9,13-14,16,19,24-25H,7-8,10-12H2/t13-,14+,16+,19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370769 (US10239835, Example 00321) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(F)cc1F |r,w:10.11| Show InChI InChI=1S/C21H23F2NO3/c22-16-3-6-21(19(23)9-16)27-18-7-14-10-24(11-15(14)8-18)12-20(26)13-1-4-17(25)5-2-13/h1-6,9,14-15,18,20,25-26H,7-8,10-12H2/t14-,15+,18+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.62	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370797 (US10239835, Example 00349) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1cccc(F)c1F |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-16-2-1-3-19(20(16)22)27-15-6-12-9-24(10-13(12)7-15)11-18(26)17-5-4-14(25)8-23-17/h1-5,8,12-13,15,18,25-26H,6-7,9-11H2/t12-,13+,15+,18?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.78	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370802 (US10239835, Example 00354) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Sc1ccccc1 |r,w:10.11| Show InChI InChI=1S/C21H25NO2S/c23-18-8-6-15(7-9-18)21(24)14-22-12-16-10-20(11-17(16)13-22)25-19-4-2-1-3-5-19/h1-9,16-17,20-21,23-24H,10-14H2/t16-,17+,20+,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.36	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370768 (US10239835, Example 00320) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1c(F)cccc1F |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-16-2-1-3-17(22)20(16)27-15-6-12-9-24(10-13(12)7-15)11-19(26)18-5-4-14(25)8-23-18/h1-5,8,12-13,15,19,25-26H,6-7,9-11H2/t12-,13+,15+,19?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370744 (US10239835, Example 00296) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccccc1 |r| Show InChI InChI=1S/C21H23NO3/c23-18-8-6-15(7-9-18)21(24)14-22-12-16-10-20(11-17(16)13-22)25-19-4-2-1-3-5-19/h1-9,16-17,20,23H,10-14H2/t16-,17+,20+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370676 (US10239835, Example 00228) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(F)cc1 |r,w:10.11| Show InChI InChI=1S/C21H24FNO3/c22-17-3-7-19(8-4-17)26-20-9-15-11-23(12-16(15)10-20)13-21(25)14-1-5-18(24)6-2-14/h1-8,15-16,20-21,24-25H,9-13H2/t15-,16+,20+,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370678 (US10239835, Example 00230) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(F)c(F)c1 |r,w:10.11| Show InChI InChI=1S/C21H23F2NO3/c22-19-6-5-17(9-20(19)23)27-18-7-14-10-24(11-15(14)8-18)12-21(26)13-1-3-16(25)4-2-13/h1-6,9,14-15,18,21,25-26H,7-8,10-12H2/t14-,15+,18+,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370782 (US10239835, Example 00334) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccc(C)cc1F |r,w:10.11| Show InChI InChI=1S/C21H25FN2O3/c1-13-2-5-21(18(22)6-13)27-17-7-14-10-24(11-15(14)8-17)12-20(26)19-4-3-16(25)9-23-19/h2-6,9,14-15,17,20,25-26H,7-8,10-12H2,1H3/t14-,15+,17+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370755 (US10239835, Example 00307) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccccc1F |r| Show InChI InChI=1S/C21H22FNO3/c22-19-3-1-2-4-21(19)26-18-9-15-11-23(12-16(15)10-18)13-20(25)14-5-7-17(24)8-6-14/h1-8,15-16,18,24H,9-13H2/t15-,16+,18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.8	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370727 (US10239835, Example 00279) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(F)cc1 |r,w:10.11| Show InChI InChI=1S/C21H24FNO3/c22-17-3-7-19(8-4-17)26-20-9-15-11-23(12-16(15)10-20)13-21(25)14-1-5-18(24)6-2-14/h1-8,15-16,20-21,24-25H,9-13H2/t15-,16+,20-,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370681 (US10239835, Example 00233) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccc(F)c(F)c1 |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-17-3-2-15(7-18(17)22)27-16-5-12-9-24(10-13(12)6-16)11-20(26)19-4-1-14(25)8-23-19/h1-4,7-8,12-13,16,20,25-26H,5-6,9-11H2/t12-,13+,16+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370694 (US10239835, Example 00246) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccc(cc1)C#N |r,w:10.11| Show InChI InChI=1S/C21H23N3O3/c22-9-14-1-4-18(5-2-14)27-19-7-15-11-24(12-16(15)8-19)13-21(26)20-6-3-17(25)10-23-20/h1-6,10,15-16,19,21,25-26H,7-8,11-13H2/t15-,16+,19+,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370809 (US10239835, Example 00361) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Sc1ccc(F)cc1 |r,w:10.11| Show InChI InChI=1S/C21H24FNO2S/c22-17-3-7-19(8-4-17)26-20-9-15-11-23(12-16(15)10-20)13-21(25)14-1-5-18(24)6-2-14/h1-8,15-16,20-21,24-25H,9-13H2/t15-,16+,20+,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370817 (US10239835, Example 00368) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(C[C@H](O)c1ccc(O)cn1)C2)Oc1cccnc1F |r| Show InChI InChI=1S/C19H22FN3O3/c20-19-18(2-1-5-21-19)26-15-6-12-9-23(10-13(12)7-15)11-17(25)16-4-3-14(24)8-22-16/h1-5,8,12-13,15,17,24-25H,6-7,9-11H2/t12-,13+,15+,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370812 (US10239835, Example 00363) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Sc1ccccc1F |r,w:10.11| Show InChI InChI=1S/C20H23FN2O2S/c21-17-3-1-2-4-20(17)26-16-7-13-10-23(11-14(13)8-16)12-19(25)18-6-5-15(24)9-22-18/h1-6,9,13-14,16,19,24-25H,7-8,10-12H2/t13-,14+,16+,19?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.6	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370749 (US10239835, Example 00301) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1cccnc1F |r,w:10.11| Show InChI InChI=1S/C19H22FN3O3/c20-19-18(2-1-5-21-19)26-15-6-12-9-23(10-13(12)7-15)11-17(25)16-4-3-14(24)8-22-16/h1-5,8,12-13,15,17,24-25H,6-7,9-11H2/t12-,13+,15+,17?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.9	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370757 (US10239835, Example 00309) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)c(F)c1)C2)Oc1cccnc1F |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-16-8-12(3-4-17(16)25)18(26)11-24-9-13-6-15(7-14(13)10-24)27-19-2-1-5-23-20(19)22/h1-5,8,13-15,18,25-26H,6-7,9-11H2/t13-,14+,15+,18?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.7	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370784 (US10239835, Example 00336) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1cccc(C)c1F |r,w:10.11| Show InChI InChI=1S/C21H25FN2O3/c1-13-3-2-4-20(21(13)22)27-17-7-14-10-24(11-15(14)8-17)12-19(26)18-6-5-16(25)9-23-18/h2-6,9,14-15,17,19,25-26H,7-8,10-12H2,1H3/t14-,15+,17+,19?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370794 (US10239835, Example 00346) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1c(F)cccc1F |r,w:10.11| Show InChI InChI=1S/C21H23F2NO3/c22-18-2-1-3-19(23)21(18)27-17-8-14-10-24(11-15(14)9-17)12-20(26)13-4-6-16(25)7-5-13/h1-7,14-15,17,20,25-26H,8-12H2/t14-,15+,17+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370801 (US10239835, Example 00353) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Sc1ccccc1 |r| Show InChI InChI=1S/C21H23NO2S/c23-18-8-6-15(7-9-18)21(24)14-22-12-16-10-20(11-17(16)13-22)25-19-4-2-1-3-5-19/h1-9,16-17,20,23H,10-14H2/t16-,17+,20+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.7	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370767 (US10239835, Example 00319) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1c(F)cccc1F |r| Show InChI InChI=1S/C21H21F2NO3/c22-18-2-1-3-19(23)21(18)27-17-8-14-10-24(11-15(14)9-17)12-20(26)13-4-6-16(25)7-5-13/h1-7,14-15,17,25H,8-12H2/t14-,15+,17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370714 (US10239835, Example 00266) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)c(F)n1)C2)Oc1ccc(F)cc1 |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-14-1-3-15(4-2-14)27-16-7-12-9-24(10-13(12)8-16)11-19(26)17-5-6-18(25)20(22)23-17/h1-6,12-13,16,19,25-26H,7-11H2/t12-,13+,16+,19?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370722 (US10239835, Example 00274) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(O)c1ccc(O)c(F)c1)C2)Oc1ccc(F)cc1 |r,w:10.11| Show InChI InChI=1S/C21H23F2NO3/c22-16-2-4-17(5-3-16)27-18-7-14-10-24(11-15(14)8-18)12-21(26)13-1-6-20(25)19(23)9-13/h1-6,9,14-15,18,21,25-26H,7-8,10-12H2/t14-,15+,18-,21?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.5	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370740 (US10239835, Example 00292) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccc(F)c(F)c1 |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-17-3-2-15(7-18(17)22)27-16-5-12-9-24(10-13(12)6-16)11-20(26)19-4-1-14(25)8-23-19/h1-4,7-8,12-13,16,20,25-26H,5-6,9-11H2/t12-,13+,16-,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37.6	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370800 (US10239835, Example 00352) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccccc1Cl |r,w:10.11| Show InChI InChI=1S/C20H23ClN2O3/c21-17-3-1-2-4-20(17)26-16-7-13-10-23(11-14(13)8-16)12-19(25)18-6-5-15(24)9-22-18/h1-6,9,13-14,16,19,24-25H,7-8,10-12H2/t13-,14+,16+,19?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370765 (US10239835, Example 00317) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(F)cc1F |r| Show InChI InChI=1S/C21H21F2NO3/c22-16-3-6-21(19(23)9-16)27-18-7-14-10-24(11-15(14)8-18)12-20(26)13-1-4-17(25)5-2-13/h1-6,9,14-15,18,25H,7-8,10-12H2/t14-,15+,18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.1	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370711 (US10239835, Example 00263) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)c(F)c1)C2)Oc1ccc(OC)cc1 |r,w:10.11| Show InChI InChI=1S/C22H26FNO4/c1-27-17-3-5-18(6-4-17)28-19-8-15-11-24(12-16(15)9-19)13-22(26)14-2-7-21(25)20(23)10-14/h2-7,10,15-16,19,22,25-26H,8-9,11-13H2,1H3/t15-,16+,19+,22?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.5	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370698 (US10239835, Example 00250) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(OC)cc1 |r| Show InChI InChI=1S/C22H25NO4/c1-26-19-6-8-20(9-7-19)27-21-10-16-12-23(13-17(16)11-21)14-22(25)15-2-4-18(24)5-3-15/h2-9,16-17,21,24H,10-14H2,1H3/t16-,17+,21+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46.4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370675 (US10239835, Example 00227) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(F)cc1 |r| Show InChI InChI=1S/C21H22FNO3/c22-17-3-7-19(8-4-17)26-20-9-15-11-23(12-16(15)10-20)13-21(25)14-1-5-18(24)6-2-14/h1-8,15-16,20,24H,9-13H2/t15-,16+,20+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370702 (US10239835, Example 00254) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(cc1)C#N |r,w:10.11| Show InChI InChI=1S/C22H24N2O3/c23-11-15-1-7-20(8-2-15)27-21-9-17-12-24(13-18(17)10-21)14-22(26)16-3-5-19(25)6-4-16/h1-8,17-18,21-22,25-26H,9-10,12-14H2/t17-,18+,21+,22?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47.4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370787 (US10239835, Example 00339) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1cccc(OC)c1F |r,w:10.11| Show InChI InChI=1S/C21H25FN2O4/c1-27-19-3-2-4-20(21(19)22)28-16-7-13-10-24(11-14(13)8-16)12-18(26)17-6-5-15(25)9-23-17/h2-6,9,13-14,16,18,25-26H,7-8,10-12H2,1H3/t13-,14+,16+,18?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50.8	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370712 (US10239835, Example 00264) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cc1)C2)Oc1ccc(OC)cc1 |r,w:10.11| Show InChI InChI=1S/C22H27NO4/c1-26-19-6-8-20(9-7-19)27-21-10-16-12-23(13-17(16)11-21)14-22(25)15-2-4-18(24)5-3-15/h2-9,16-17,21-22,24-25H,10-14H2,1H3/t16-,17+,21+,22?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51.6	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370705 (US10239835, Example 00257) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)c(F)c1)C2)Oc1cccnc1 |r,w:10.11| Show InChI InChI=1S/C20H23FN2O3/c21-18-8-13(3-4-19(18)24)20(25)12-23-10-14-6-17(7-15(14)11-23)26-16-2-1-5-22-9-16/h1-5,8-9,14-15,17,20,24-25H,6-7,10-12H2/t14-,15+,17+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52.1	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370721 (US10239835, Example 00273) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(=O)c1ccc(O)c(F)c1)C2)Oc1ccc(F)cc1 |r| Show InChI InChI=1S/C21H21F2NO3/c22-16-2-4-17(5-3-16)27-18-7-14-10-24(11-15(14)8-18)12-21(26)13-1-6-20(25)19(23)9-13/h1-6,9,14-15,18,25H,7-8,10-12H2/t14-,15+,18-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53.2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370689 (US10239835, Example 00241) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(F)cc1 |r| Show InChI InChI=1S/C21H22FNO3/c22-17-3-7-19(8-4-17)26-20-9-15-11-23(12-16(15)10-20)13-21(25)14-1-5-18(24)6-2-14/h1-8,15-16,20,24H,9-13H2/t15-,16+,20-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53.4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370758 (US10239835, Example 00310) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(F)nc1 |r| Show InChI InChI=1S/C20H21FN2O3/c21-20-6-5-17(9-22-20)26-18-7-14-10-23(11-15(14)8-18)12-19(25)13-1-3-16(24)4-2-13/h1-6,9,14-15,18,24H,7-8,10-12H2/t14-,15+,18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55.2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370718 (US10239835, Example 00270) Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(OC)cc1 |r| Show InChI InChI=1S/C22H25NO4/c1-26-19-6-8-20(9-7-19)27-21-10-16-12-23(13-17(16)11-21)14-22(25)15-2-4-18(24)5-3-15/h2-9,16-17,21,24H,10-14H2,1H3/t16-,17+,21-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	57.3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370683 (US10239835, Example 00235) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1cc(F)cc(F)c1 |r,w:10.11| Show InChI InChI=1S/C20H22F2N2O3/c21-14-5-15(22)7-18(6-14)27-17-3-12-9-24(10-13(12)4-17)11-20(26)19-2-1-16(25)8-23-19/h1-2,5-8,12-13,17,20,25-26H,3-4,9-11H2/t12-,13+,17+,20?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58.3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370799 (US10239835, Example 00351) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(O)c1ccc(O)cn1)C2)Oc1ccc(C)nc1F |r,w:10.11| Show InChI InChI=1S/C20H24FN3O3/c1-12-2-5-19(20(21)23-12)27-16-6-13-9-24(10-14(13)7-16)11-18(26)17-4-3-15(25)8-22-17/h2-5,8,13-14,16,18,25-26H,6-7,9-11H2,1H3/t13-,14+,16+,18?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60.2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM370677 (US10239835, Example 00229) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])CN(CC(=O)c1ccc(O)cc1)C2)Oc1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C21H21F2NO3/c22-19-6-5-17(9-20(19)23)27-18-7-14-10-24(11-15(14)8-18)12-21(26)13-1-3-16(25)4-2-13/h1-6,9,14-15,18,25H,7-8,10-12H2/t14-,15+,18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61.6	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2F19207
					More data for this Ligand-Target Pair

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