Compile Data Set for Download or QSAR

Found 143 hits Enz. Inhib. hit(s) with all data for entry = 277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261893 (2-(6-Chloro-9-ethyl-9H-carbazol-3-yl)-1-(2-methoxy...) Show SMILES CCn1c2ccc(Cl)cc2c2cc(ccc12)-c1nc2c(C)c(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C26H24ClN3O3/c1-4-29-21-8-5-16(13-19(21)20-14-17(27)6-9-22(20)29)25-28-24-15(2)18(26(31)32)7-10-23(24)30(25)11-12-33-3/h5-10,13-14H,4,11-12H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.16	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261894 (2-(8-Chloro-9-ethyl-9H-carbazol-3-yl)-1-(2-methoxy...) Show SMILES CCn1c2ccc(cc2c2cccc(Cl)c12)-c1nc2c(C)c(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C26H24ClN3O3/c1-4-29-21-10-8-16(14-19(21)18-6-5-7-20(27)24(18)29)25-28-23-15(2)17(26(31)32)9-11-22(23)30(25)12-13-33-3/h5-11,14H,4,12-13H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.19	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261752 (3-Amino-4-[(2-methoxyethyl)amino]benzoic acid | US...) Show SMILES COCCNc1ccc(cc1N)C(O)=O Show InChI InChI=1S/C10H14N2O3/c1-15-5-4-12-9-3-2-7(10(13)14)6-8(9)11/h2-3,6,12H,4-5,11H2,1H3,(H,13,14)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	5.59	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261760 (2-(9-Ethyl-5-fluoro-9H-carbazol-3-yl)-1-(2-methoxy...) Show SMILES CCn1c2ccc(cc2c2c(F)cccc12)-c1nc2cc(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C25H22FN3O3/c1-3-28-20-9-7-15(13-17(20)23-18(26)5-4-6-22(23)28)24-27-19-14-16(25(30)31)8-10-21(19)29(24)11-12-32-2/h4-10,13-14H,3,11-12H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.36	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261864 (2-(9-Ethyl-9H-carbazol-3-yl)-4-fluoro-1-(2-methoxy...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2c(F)c(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C25H22FN3O3/c1-3-28-19-7-5-4-6-16(19)18-14-15(8-10-20(18)28)24-27-23-21(29(24)12-13-32-2)11-9-17(22(23)26)25(30)31/h4-11,14H,3,12-13H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.42	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261884 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(tetrahydrofuran-2-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CC1CCCO1)C(O)=O Show InChI InChI=1S/C27H25N3O3/c1-2-29-23-8-4-3-7-20(23)21-14-17(9-11-24(21)29)26-28-22-15-18(27(31)32)10-12-25(22)30(26)16-19-6-5-13-33-19/h3-4,7-12,14-15,19H,2,5-6,13,16H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261761 (2-(9-Ethyl-8-fluoro-9H-carbazol-3-yl)-1-(2-methoxy...) Show SMILES CCn1c2ccc(cc2c2cccc(F)c12)-c1nc2cc(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C25H22FN3O3/c1-3-28-21-9-7-15(13-18(21)17-5-4-6-19(26)23(17)28)24-27-20-14-16(25(30)31)8-10-22(20)29(24)11-12-32-2/h4-10,13-14H,3,11-12H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261759 (2-(9-Ethyl-7-fluoro-9H-carbazol-3-yl)-1-(2-methoxy...) Show SMILES CCn1c2ccc(cc2c2ccc(F)cc12)-c1nc2cc(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C25H22FN3O3/c1-3-28-21-8-4-15(12-19(21)18-7-6-17(26)14-23(18)28)24-27-20-13-16(25(30)31)5-9-22(20)29(24)10-11-32-2/h4-9,12-14H,3,10-11H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.3	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261865 (1-(Cyclopropylmethyl)-2-(9-ethyl-9H-carbazol-3-yl)...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2c(F)c(ccc2n1CC1CC1)C(O)=O Show InChI InChI=1S/C26H22FN3O2/c1-2-29-20-6-4-3-5-17(20)19-13-16(9-11-21(19)29)25-28-24-22(30(25)14-15-7-8-15)12-10-18(23(24)27)26(31)32/h3-6,9-13,15H,2,7-8,14H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261795 (3-[2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)-c1noc(=O)[nH]1 Show InChI InChI=1S/C26H23N5O3/c1-3-30-21-7-5-4-6-18(21)19-14-17(9-10-22(19)30)25-27-20-15-16(24-28-26(32)34-29-24)8-11-23(20)31(25)12-13-33-2/h4-11,14-15H,3,12-13H2,1-2H3,(H,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.4	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261785 (2-[9-(Cyclopropylmethyl)-9H-carbazol-3-yl]-1-(2-me...) Show SMILES COCCn1c(nc2cc(ccc12)C(O)=O)-c1ccc2n(CC3CC3)c3ccccc3c2c1 Show InChI InChI=1S/C27H25N3O3/c1-33-13-12-29-25-11-9-19(27(31)32)15-22(25)28-26(29)18-8-10-24-21(14-18)20-4-2-3-5-23(20)30(24)16-17-6-7-17/h2-5,8-11,14-15,17H,6-7,12-13,16H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.1	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261794 (9-Ethyl-3-[1-(2-methoxyethyl)-5-(1H-tetrazol-5-yl)...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)-c1nnn[nH]1 Show InChI InChI=1S/C25H23N7O/c1-3-31-21-7-5-4-6-18(21)19-14-17(9-10-22(19)31)25-26-20-15-16(24-27-29-30-28-24)8-11-23(20)32(25)12-13-33-2/h4-11,14-15H,3,12-13H2,1-2H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.4	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261881 (2-(9-Ethyl-9H-carbazol-3-yl)-1-[2-(trifluoromethox...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC(F)(F)F)C(O)=O Show InChI InChI=1S/C25H20F3N3O3/c1-2-30-20-6-4-3-5-17(20)18-13-15(7-9-21(18)30)23-29-19-14-16(24(32)33)8-10-22(19)31(23)11-12-34-25(26,27)28/h3-10,13-14H,2,11-12H2,1H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.3	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261754 (4-Bromo-3-chloro-N-(cyclopropylmethyl)-2-nitroanil...) Show SMILES [O-][N+](=O)c1c(Cl)c(Br)ccc1NCC1CC1 Show InChI InChI=1S/C10H10BrClN2O2/c11-7-3-4-8(13-5-6-1-2-6)10(9(7)12)14(15)16/h3-4,6,13H,1-2,5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.4	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261766 (N-[(3-Chlorophenyl)sulphonyl]-2-(9-ethyl-9H-carbaz...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C31H27ClN4O4S/c1-3-35-27-10-5-4-9-24(27)25-17-20(11-13-28(25)35)30-33-26-18-21(12-14-29(26)36(30)15-16-40-2)31(37)34-41(38,39)23-8-6-7-22(32)19-23/h4-14,17-19H,3,15-16H2,1-2H3,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.7	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261892 (2-(9-Ethyl-6-methyl-9H-carbazol-3-yl)-1-(2-methoxy...) Show SMILES CCn1c2ccc(C)cc2c2cc(ccc12)-c1nc2c(C)c(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C27H27N3O3/c1-5-29-22-9-6-16(2)14-20(22)21-15-18(7-10-23(21)29)26-28-25-17(3)19(27(31)32)8-11-24(25)30(26)12-13-33-4/h6-11,14-15H,5,12-13H2,1-4H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	15.3	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261815 (N-[(2,2-Dimethylpropyl)sulphonyl]-2-(9-ethyl-9H-ca...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)CC(C)(C)C Show InChI InChI=1S/C30H34N4O4S/c1-6-33-25-10-8-7-9-22(25)23-17-20(11-13-26(23)33)28-31-24-18-21(12-14-27(24)34(28)15-16-38-5)29(35)32-39(36,37)19-30(2,3)4/h7-14,17-18H,6,15-16,19H2,1-5H3,(H,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.1	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261846 (2-(9-Allyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-1H...) Show SMILES COCCn1c(nc2cc(ccc12)C(O)=O)-c1ccc2n(CC=C)c3ccccc3c2c1 Show InChI InChI=1S/C26H23N3O3/c1-3-12-28-22-7-5-4-6-19(22)20-15-17(8-10-23(20)28)25-27-21-16-18(26(30)31)9-11-24(21)29(25)13-14-32-2/h3-11,15-16H,1,12-14H2,2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261808 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)CCOC Show InChI InChI=1S/C28H30N4O5S/c1-4-31-24-8-6-5-7-21(24)22-17-19(9-11-25(22)31)27-29-23-18-20(10-12-26(23)32(27)13-14-36-2)28(33)30-38(34,35)16-15-37-3/h5-12,17-18H,4,13-16H2,1-3H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.9	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261803 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)c1ccccc1OC(F)(F)F Show InChI InChI=1S/C32H27F3N4O5S/c1-3-38-25-9-5-4-8-22(25)23-18-20(12-14-26(23)38)30-36-24-19-21(13-15-27(24)39(30)16-17-43-2)31(40)37-45(41,42)29-11-7-6-10-28(29)44-32(33,34)35/h4-15,18-19H,3,16-17H2,1-2H3,(H,37,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.6	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261762 (9-Ethyl-5-fluoro-9H-carbazole-3-carbaldehyde | US9...) Show SMILES CCn1c2ccc(C=O)cc2c2c(F)cccc12 Show InChI InChI=1S/C15H12FNO/c1-2-17-13-7-6-10(9-18)8-11(13)15-12(16)4-3-5-14(15)17/h3-9H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261888 (1-(2-Cyclopropyl-2-hydroxyethyl)-2-(9-ethyl-9H-car...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CC(O)C1CC1)C(O)=O Show InChI InChI=1S/C27H25N3O3/c1-2-29-22-6-4-3-5-19(22)20-13-17(9-11-23(20)29)26-28-21-14-18(27(32)33)10-12-24(21)30(26)15-25(31)16-7-8-16/h3-6,9-14,16,25,31H,2,7-8,15H2,1H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.6	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261756 (3-[5-Bromo-4-chloro-1-(cyclopropylmethyl)-1H-benzi...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2c(Cl)c(Br)ccc2n1CC1CC1 Show InChI InChI=1S/C25H21BrClN3/c1-2-29-20-6-4-3-5-17(20)18-13-16(9-11-21(18)29)25-28-24-22(12-10-19(26)23(24)27)30(25)14-15-7-8-15/h3-6,9-13,15H,2,7-8,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.7	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261809 (N-[(2,6-Dichlorbenzyl)sulphonyl]-2-(9-ethyl-9H-car...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)Cc1c(Cl)cccc1Cl Show InChI InChI=1S/C32H28Cl2N4O4S/c1-3-37-28-10-5-4-7-22(28)23-17-20(11-13-29(23)37)31-35-27-18-21(12-14-30(27)38(31)15-16-42-2)32(39)36-43(40,41)19-24-25(33)8-6-9-26(24)34/h4-14,17-18H,3,15-16,19H2,1-2H3,(H,36,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.8	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261824 (1-[2-(Dimethylamino)ethyl]-2-(9-ethyl-9H-carbazol-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCN(C)C)C(=O)NS(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C33H33N5O3S/c1-5-37-29-9-7-6-8-26(29)27-20-23(12-16-30(27)37)32-34-28-21-24(13-17-31(28)38(32)19-18-36(3)4)33(39)35-42(40,41)25-14-10-22(2)11-15-25/h6-17,20-21H,5,18-19H2,1-4H3,(H,35,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.4	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261867 (1-(2-Cyclopropylethyl)-2-(9-ethyl-9H-carbazol-3-yl...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCC1CC1)C(O)=O Show InChI InChI=1S/C27H25N3O2/c1-2-29-23-6-4-3-5-20(23)21-15-18(9-11-24(21)29)26-28-22-16-19(27(31)32)10-12-25(22)30(26)14-13-17-7-8-17/h3-6,9-12,15-17H,2,7-8,13-14H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.1	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261866 (1-(Cyclopropylmethyl)-2-(9-ethyl-9H-pyrido[2,3-b]i...) Show SMILES CCn1c2ccc(cc2c2cccnc12)-c1nc2cc(ccc2n1CC1CC1)C(O)=O Show InChI InChI=1S/C25H22N4O2/c1-2-28-21-9-7-16(12-19(21)18-4-3-11-26-24(18)28)23-27-20-13-17(25(30)31)8-10-22(20)29(23)14-15-5-6-15/h3-4,7-13,15H,2,5-6,14H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.2	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261767 (2-Chloro-5-ethyl-5H-pyrido[3,2-b]indole | US970831...) Show SMILES CCn1c2ccccc2c2nc(Cl)ccc12 Show InChI InChI=1S/C13H11ClN2/c1-2-16-10-6-4-3-5-9(10)13-11(16)7-8-12(14)15-13/h3-8H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.8	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261764 (9-(2-Methoxyethyl)-9H-carbazole-3-carbaldehyde | U...) Show SMILES COCCn1c2ccccc2c2cc(C=O)ccc12 Show InChI InChI=1S/C16H15NO2/c1-19-9-8-17-15-5-3-2-4-13(15)14-10-12(11-18)6-7-16(14)17/h2-7,10-11H,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.8	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261883 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(oxetan-2-ylmethyl)...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CC1CCO1)C(O)=O Show InChI InChI=1S/C26H23N3O3/c1-2-28-22-6-4-3-5-19(22)20-13-16(7-9-23(20)28)25-27-21-14-17(26(30)31)8-10-24(21)29(25)15-18-11-12-32-18/h3-10,13-14,18H,2,11-12,15H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.5	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261796 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)c1cccc(C)c1 Show InChI InChI=1S/C32H30N4O4S/c1-4-35-28-11-6-5-10-25(28)26-19-22(12-14-29(26)35)31-33-27-20-23(13-15-30(27)36(31)16-17-40-3)32(37)34-41(38,39)24-9-7-8-21(2)18-24/h5-15,18-20H,4,16-17H2,1-3H3,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.6	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261781 (3-(5-Bromo-4-fluoro-1H-benzimidazol-2-yl)-9-ethyl-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2c(F)c(Br)ccc2[nH]1 Show InChI InChI=1S/C21H15BrFN3/c1-2-26-17-6-4-3-5-13(17)14-11-12(7-10-18(14)26)21-24-16-9-8-15(22)19(23)20(16)25-21/h3-11H,2H2,1H3,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.4	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261765 (9-Ethyl-6-methoxy-9H-carbazole-3-carbaldehyde | US...) Show SMILES CCn1c2ccc(OC)cc2c2cc(C=O)ccc12 Show InChI InChI=1S/C16H15NO2/c1-3-17-15-6-4-11(10-18)8-13(15)14-9-12(19-2)5-7-16(14)17/h4-10H,3H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.6	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261782 (2-(9-Allyl-9H-carbazol-3-yl)-1-(cyclopropylmethyl)...) Show SMILES OC(=O)c1ccc2n(CC3CC3)c(nc2c1)-c1ccc2n(CC=C)c3ccccc3c2c1 Show InChI InChI=1S/C27H23N3O2/c1-2-13-29-23-6-4-3-5-20(23)21-14-18(9-11-24(21)29)26-28-22-15-19(27(31)32)10-12-25(22)30(26)16-17-7-8-17/h2-6,9-12,14-15,17H,1,7-8,13,16H2,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.7	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261779 (Ethyl 3-amino-4-[(3-methoxypropyl)amino]benzoate |...) Show SMILES CCOC(=O)c1ccc(NCCCOC)c(N)c1 Show InChI InChI=1S/C13H20N2O3/c1-3-18-13(16)10-5-6-12(11(14)9-10)15-7-4-8-17-2/h5-6,9,15H,3-4,7-8,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	30.1	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261768 (Methyl 5-ethyl-5H-pyrido[3,2-b]indole-2-carboxylat...) Show SMILES CCn1c2ccccc2c2nc(ccc12)C(=O)OC Show InChI InChI=1S/C15H14N2O2/c1-3-17-12-7-5-4-6-10(12)14-13(17)9-8-11(16-14)15(18)19-2/h4-9H,3H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.2	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261763 (1-(Cyclopropylmethyl)-2-(9-ethyl-9H-pyrido[2,3-b]i...) Show SMILES CCn1c2ccccc2c2cc(cnc12)-c1nc2cc(ccc2n1CC1CC1)C(O)=O Show InChI InChI=1S/C25H22N4O2/c1-2-28-21-6-4-3-5-18(21)19-11-17(13-26-24(19)28)23-27-20-12-16(25(30)31)9-10-22(20)29(23)14-15-7-8-15/h3-6,9-13,15H,2,7-8,14H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.4	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261799 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C31H28N4O4S/c1-3-34-27-12-8-7-11-24(27)25-19-21(13-15-28(25)34)30-32-26-20-22(14-16-29(26)35(30)17-18-39-2)31(36)33-40(37,38)23-9-5-4-6-10-23/h4-16,19-20H,3,17-18H2,1-2H3,(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.6	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261784 (6-Chloro-9-ethyl-9H-carbazole-3-carbaldehyde and 8...) Show SMILES CCn1c2ccc(Cl)cc2c2cc(C=O)ccc12 Show InChI InChI=1S/C15H12ClNO/c1-2-17-14-5-3-10(9-18)7-12(14)13-8-11(16)4-6-15(13)17/h3-9H,2H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.8	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261862 (1-(Cyclopropylmethyl)-2-(9-ethyl-9H-carbazol-3-yl)...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(C(O)=O)c(F)cc2n1CC1CC1 Show InChI InChI=1S/C26H22FN3O2/c1-2-29-22-6-4-3-5-17(22)18-11-16(9-10-23(18)29)25-28-21-12-19(26(31)32)20(27)13-24(21)30(25)14-15-7-8-15/h3-6,9-13,15H,2,7-8,14H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.6	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261802 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H30N4O4S/c1-4-35-27-11-7-6-10-24(27)25-19-22(13-15-28(25)35)31-33-26-20-23(14-16-29(26)36(31)17-18-40-3)32(37)34-41(38,39)30-12-8-5-9-21(30)2/h5-16,19-20H,4,17-18H2,1-3H3,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.3	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261801 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)c1ccccc1OC Show InChI InChI=1S/C32H30N4O5S/c1-4-35-26-10-6-5-9-23(26)24-19-21(13-15-27(24)35)31-33-25-20-22(14-16-28(25)36(31)17-18-40-2)32(37)34-42(38,39)30-12-8-7-11-29(30)41-3/h5-16,19-20H,4,17-18H2,1-3H3,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.9	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261868 (1-(2-Methoxyethyl)-2-(9-propyl-9H-carbazol-3-yl)-1...) Show SMILES CCCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C26H25N3O3/c1-3-12-28-22-7-5-4-6-19(22)20-15-17(8-10-23(20)28)25-27-21-16-18(26(30)31)9-11-24(21)29(25)13-14-32-2/h4-11,15-16H,3,12-14H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.2	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261817 (2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-N-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)Cc1ncccc1C Show InChI InChI=1S/C32H31N5O4S/c1-4-36-28-10-6-5-9-24(28)25-18-22(11-13-29(25)36)31-34-26-19-23(12-14-30(26)37(31)16-17-41-3)32(38)35-42(39,40)20-27-21(2)8-7-15-33-27/h5-15,18-19H,4,16-17,20H2,1-3H3,(H,35,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.3	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261816 (N-[(2-Chloro-6-methylbenzyl)sulphonyl]-2-(9-ethyl-...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)Cc1c(C)cccc1Cl Show InChI InChI=1S/C33H31ClN4O4S/c1-4-37-29-11-6-5-9-24(29)25-18-22(12-14-30(25)37)32-35-28-19-23(13-15-31(28)38(32)16-17-42-3)33(39)36-43(40,41)20-26-21(2)8-7-10-27(26)34/h5-15,18-19H,4,16-17,20H2,1-3H3,(H,36,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.9	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261783 (1-(Cyclopropylmethyl)-2-(9-methyl-9H-carbazol-3-yl...) Show SMILES Cn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CC1CC1)C(O)=O Show InChI InChI=1S/C25H21N3O2/c1-27-21-5-3-2-4-18(21)19-12-16(8-10-22(19)27)24-26-20-13-17(25(29)30)9-11-23(20)28(24)14-15-6-7-15/h2-5,8-13,15H,6-7,14H2,1H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.4	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261825 (US9708311, 76 | [2-(9-Ethyl-9H-carbazol-3-yl)-1-(2...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)N1CCCC1 Show InChI InChI=1S/C29H30N4O2/c1-3-32-25-9-5-4-8-22(25)23-18-20(10-12-26(23)32)28-30-24-19-21(29(34)31-14-6-7-15-31)11-13-27(24)33(28)16-17-35-2/h4-5,8-13,18-19H,3,6-7,14-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.3	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261780 (2-(9-Ethyl-9H-carbazol-3-yl)-N,1-bis(2-methoxyethy...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NCCOC Show InChI InChI=1S/C28H30N4O3/c1-4-31-24-8-6-5-7-21(24)22-17-19(9-11-25(22)31)27-30-23-18-20(28(33)29-13-15-34-2)10-12-26(23)32(27)14-16-35-3/h5-12,17-18H,4,13-16H2,1-3H3,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.8	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261869 (1-(2-Methoxyethyl)-2-[9-(prop-2-yn-1-yl)-9H-carbaz...) Show SMILES COCCn1c(nc2cc(ccc12)C(O)=O)-c1ccc2n(CC#C)c3ccccc3c2c1 Show InChI InChI=1S/C26H21N3O3/c1-3-12-28-22-7-5-4-6-19(22)20-15-17(8-10-23(20)28)25-27-21-16-18(26(30)31)9-11-24(21)29(25)13-14-32-2/h1,4-11,15-16H,12-14H2,2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.7	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM261856 (5-[2-(9-Ethyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)...) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)-c1n[nH]c(=O)o1 Show InChI InChI=1S/C26H23N5O3/c1-3-30-21-7-5-4-6-18(21)19-14-16(8-10-22(19)30)24-27-20-15-17(25-28-29-26(32)34-25)9-11-23(20)31(24)12-13-33-2/h4-11,14-15H,3,12-13H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.7	n/a	n/a	n/a	n/a	n/a	25
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...				US Patent US9708311 (2017) BindingDB Entry DOI: 10.7270/Q23F4RPM
					More data for this Ligand-Target Pair

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