Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24969 ([(2-{[(benzyloxy)carbonyl]amino}acetamido)methyl](...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 170 | -39.3 | 1.80E+3 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24969 ([(2-{[(benzyloxy)carbonyl]amino}acetamido)methyl](...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 450 | -36.8 | 3.10E+3 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24971 (({[(benzyloxy)carbonyl]amino}methyl)(methyl)sulfan...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.40E+4 | -28.2 | 1.58E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24971 (({[(benzyloxy)carbonyl]amino}methyl)(methyl)sulfan...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.75E+4 | -27.6 | 1.12E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24967 (methyl[(methylamino)methyl]phosphinic acid | organ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.80E+4 | -27.5 | 6.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24962 ([(2-aminoacetamido)methyl](methyl)phosphinic acid ...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.10E+4 | -27.1 | 6.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24965 (organophosphorus derivative, 6 | {[(2S)-2-amino-3-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.50E+4 | -26.7 | 8.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24967 (methyl[(methylamino)methyl]phosphinic acid | organ...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.70E+4 | -26.5 | 1.53E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24962 ([(2-aminoacetamido)methyl](methyl)phosphinic acid ...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.00E+4 | -26.2 | 8.60E+4 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24965 (organophosphorus derivative, 6 | {[(2S)-2-amino-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.26E+4 | -26.0 | 1.83E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24966 (organophosphorus derivative, 7 | {[(2S)-2-amino-3-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.70E+4 | -25.7 | 1.50E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24966 (organophosphorus derivative, 7 | {[(2S)-2-amino-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.10E+4 | -25.5 | 3.42E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24968 (({[(benzyloxy)carbonyl]amino}methyl)(methyl)phosph...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 4.30E+4 | -25.3 | 1.23E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24968 (({[(benzyloxy)carbonyl]amino}methyl)(methyl)phosph...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 6.50E+4 | -24.3 | 3.19E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24963 (organophosphorus derivative, 4 | {[(2S)-2-amino-3-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.20E+5 | -22.8 | 4.85E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24970 ([(2-{[(benzyloxy)carbonyl]amino}acetamido)methyl](...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.35E+5 | -22.5 | 4.50E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24964 (organophosphorus derivative, 5 | {[(2S)-2-amino-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.76E+5 | -21.8 | 7.54E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24970 ([(2-{[(benzyloxy)carbonyl]amino}acetamido)methyl](...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.78E+5 | -21.8 | 6.40E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24963 (organophosphorus derivative, 4 | {[(2S)-2-amino-3-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.08E+5 | -21.4 | 6.17E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24964 (organophosphorus derivative, 5 | {[(2S)-2-amino-3-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.15E+5 | -21.3 | 6.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha/beta/gamma (Bacillus pasteurii) | BDBM24960 ((aminomethyl)(methyl)phosphinic acid | organophosp...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 3.40E+5 | -20.1 | 1.10E+6 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha [F36L]/beta/gamma (Proteus vulgaris) | BDBM24960 ((aminomethyl)(methyl)phosphinic acid | organophosp...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 4.25E+5 | -19.6 | 2.53E+6 | n/a | n/a | n/a | n/a | 7.0 | 30 |
Wroclaw University of Technology | Assay Description Progress curves were obtained by initiation of urease reaction with addition of purified enzyme into assay mixtures containing increasing concentrati... | J Med Chem 51: 5736-44 (2008) Article DOI: 10.1021/jm800570q BindingDB Entry DOI: 10.7270/Q2PR7T91 | |||||||||||
More data for this Ligand-Target Pair |