Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil collagenase (Homo sapiens (Human)) | BDBM26791![]() (benzimidazole analog., 17 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.87E+3 | -32.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil collagenase (Homo sapiens (Human)) | BDBM26789![]() (benzimidazole analog., 15 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.96E+3 | -32.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM26791![]() (benzimidazole analog., 17 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.61E+3 | -31.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil collagenase (Homo sapiens (Human)) | BDBM26793![]() (benzimidazole analog., 19 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >3.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrilysin (Homo sapiens (Human)) | BDBM26793![]() (benzimidazole analog., 19 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.50E+3 | -31.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM26793![]() (benzimidazole analog., 19 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.92E+3 | -30.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrilysin (Homo sapiens (Human)) | BDBM26789![]() (benzimidazole analog., 15 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.08E+3 | -30.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM26789![]() (benzimidazole analog., 15 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM26789![]() (benzimidazole analog., 15 | tert-butyl (3S,4S)-3-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM26793![]() (benzimidazole analog., 19 | tert-butyl (3S,4S)-3-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM26791![]() (benzimidazole analog., 17 | tert-butyl (3S,4S)-3-(...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | >5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrilysin (Homo sapiens (Human)) | BDBM26791![]() (benzimidazole analog., 17 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.86E+3 | -29.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26807![]() ((3R,4S)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26795![]() (N-[(1R,2S)-2-(hydroxycarbamoyl)cyclopentyl]-4-{[2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26793![]() (benzimidazole analog., 19 | tert-butyl (3S,4S)-3-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26791![]() (benzimidazole analog., 17 | tert-butyl (3S,4S)-3-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26789![]() (benzimidazole analog., 15 | tert-butyl (3S,4S)-3-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26802![]() ((5R,7R,8S)-7-N-(4-{[2-(2-fluoropropan-2-yl)-1H-1,3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26799![]() ((5R,7S,8R)-7-N-hydroxy-8-N-(4-{[2-(propan-2-yl)-1H...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26800![]() ((5R,7R,8S)-7-N-{4-[(2-cyclopropyl-1H-1,3-benzodiaz...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26806![]() ((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26803![]() ((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(propan-2-yl)-1H-1,...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26790![]() ((3S,4S)-3-N-hydroxy-4-N-(4-{[2-(methylsulfanyl)-1H...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26794![]() ((3S,4S)-3-N-hydroxy-4-N-(4-{[2-(propan-2-yl)-1H-1,...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26797![]() ((3S,4S)-3-N-hydroxy-1-(prop-2-yn-1-yl)-4-N-(4-{[2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26801![]() ((5R,7R,8S)-7-N-{4-[(2-tert-butyl-1H-1,3-benzodiazo...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26804![]() ((3R,4R)-4-N-(4-{[2-(2-fluoropropan-2-yl)-1H-1,3-be...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26798![]() ((3S,4S)-3-N-{4-[(2-tert-butyl-1H-1,3-benzodiazol-1...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26792![]() ((3S,4S)-3-N-hydroxy-4-N-{4-[(2-methyl-1H-1,3-benzo...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26805![]() ((3R,4R)-4-N-(4-{[2-(1,1-difluoroethyl)-1H-1,3-benz...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig)) | BDBM26796![]() (4-[(2-cyclopropyl-1H-1,3-benzodiazol-1-yl)methyl]-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM26791![]() (benzimidazole analog., 17 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM26793![]() (benzimidazole analog., 19 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM26789![]() (benzimidazole analog., 15 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-2 (Homo sapiens (Human)) | BDBM26791![]() (benzimidazole analog., 17 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-2 (Homo sapiens (Human)) | BDBM26793![]() (benzimidazole analog., 19 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM26806![]() ((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-2 (Homo sapiens (Human)) | BDBM26789![]() (benzimidazole analog., 15 | tert-butyl (3S,4S)-3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company | Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i... | Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS | |||||||||||
More data for this Ligand-Target Pair |