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Compile Data Set for Download or QSAR

Found 724 hits Enz. Inhib. hit(s) with all data for entry = 3191   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393728
PNG
(US10597367, Example 18 | US9969726, Example 18)
Show SMILES OC(=O)c1cc(ccc1F)-c1ccccc1-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H14FNO2S/c23-19-11-10-15(12-18(19)22(25)26)16-8-4-5-9-17(16)20-13-27-21(24-20)14-6-2-1-3-7-14/h1-13H,(H,25,26)
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393728
PNG
(US10597367, Example 18 | US9969726, Example 18)
Show SMILES OC(=O)c1cc(ccc1F)-c1ccccc1-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H14FNO2S/c23-19-11-10-15(12-18(19)22(25)26)16-8-4-5-9-17(16)20-13-27-21(24-20)14-6-2-1-3-7-14/h1-13H,(H,25,26)
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
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n/an/an/an/a 3.67E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
PDB

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n/an/an/an/a 1.55E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393729
PNG
(US10597367, Example 19 | US9969726, Example 19)
Show SMILES COc1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H16FNOS/c1-25-21-13-17(10-11-19(21)23)16-8-5-9-18(12-16)20-14-26-22(24-20)15-6-3-2-4-7-15/h2-14H,1H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393730
PNG
(US9969726, Example 20)
Show SMILES O\N=C/c1cc(ccc1F)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15FN2OS/c23-20-10-9-17(12-19(20)13-24-26)16-7-4-8-18(11-16)21-14-27-22(25-21)15-5-2-1-3-6-15/h1-14,26H/b24-13-
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393731
PNG
(US10597367, Example 21 | US9969726, Example 21)
Show SMILES Clc1cccc(c1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-5-9-17(13-19)16-8-4-10-18(12-16)20-14-24-21(23-20)15-6-2-1-3-7-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
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n/an/an/an/a 1.81E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
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n/an/an/an/a 1.35E+3n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393733
PNG
(US10597367, Example 23 | US9969726, Example 23)
Show SMILES COc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H17NOS/c1-24-21-13-6-5-12-19(21)17-10-7-11-18(14-17)20-15-25-22(23-20)16-8-3-2-4-9-16/h2-15H,1H3
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
PDB

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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393734
PNG
(US10597367, Example 24 | US9969726, Example 24)
Show SMILES Clc1ccc(cc1)-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-11-9-15(10-12-19)17-7-4-8-18(13-17)20-14-24-21(23-20)16-5-2-1-3-6-16/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393735
PNG
(US10597367, Example 25 | US9969726, Example 25)
Show SMILES OC(=O)c1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C22H15NO2S/c24-22(25)19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-26-21(23-20)15-7-2-1-3-8-15/h1-14H,(H,24,25)
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393736
PNG
(US10597367, Example 26 | US9969726, Example 26)
Show SMILES Clc1ccccc1-c1cccc(c1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C21H14ClNS/c22-19-12-5-4-11-18(19)16-9-6-10-17(13-16)20-14-24-21(23-20)15-7-2-1-3-8-15/h1-14H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393737
PNG
(US10597367, Example 27 | US9969726, Example 27)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-c1ccccc1
Show InChI InChI=1S/C15H10FNS/c16-13-8-6-11(7-9-13)14-10-18-15(17-14)12-4-2-1-3-5-12/h1-10H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393732
PNG
(US10597367, Example 28 | US9969726, Example 22 | U...)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393739
PNG
(US10597367, Example 29 | US9969726, Example 29)
Show SMILES COc1ccc(cc1OC)-c1nc(cs1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H19NO2S/c1-25-21-12-11-19(14-22(21)26-2)23-24-20(15-27-23)18-10-6-9-17(13-18)16-7-4-3-5-8-16/h3-15H,1-2H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393739
PNG
(US10597367, Example 29 | US9969726, Example 29)
Show SMILES COc1ccc(cc1OC)-c1nc(cs1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H19NO2S/c1-25-21-12-11-19(14-22(21)26-2)23-24-20(15-27-23)18-10-6-9-17(13-18)16-7-4-3-5-8-16/h3-15H,1-2H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393739
PNG
(US10597367, Example 29 | US9969726, Example 29)
Show SMILES COc1ccc(cc1OC)-c1nc(cs1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H19NO2S/c1-25-21-12-11-19(14-22(21)26-2)23-24-20(15-27-23)18-10-6-9-17(13-18)16-7-4-3-5-8-16/h3-15H,1-2H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393739
PNG
(US10597367, Example 29 | US9969726, Example 29)
Show SMILES COc1ccc(cc1OC)-c1nc(cs1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H19NO2S/c1-25-21-12-11-19(14-22(21)26-2)23-24-20(15-27-23)18-10-6-9-17(13-18)16-7-4-3-5-8-16/h3-15H,1-2H3
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Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393740
PNG
(US10597367, Example 30 | US9969726, Example 30)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1cccc2ccccc12
Show InChI InChI=1S/C25H17NS/c1-2-8-18(9-3-1)20-12-6-13-21(16-20)24-17-27-25(26-24)23-15-7-11-19-10-4-5-14-22(19)23/h1-17H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM393740
PNG
(US10597367, Example 30 | US9969726, Example 30)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1cccc2ccccc12
Show InChI InChI=1S/C25H17NS/c1-2-8-18(9-3-1)20-12-6-13-21(16-20)24-17-27-25(26-24)23-15-7-11-19-10-4-5-14-22(19)23/h1-17H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393740
PNG
(US10597367, Example 30 | US9969726, Example 30)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1cccc2ccccc12
Show InChI InChI=1S/C25H17NS/c1-2-8-18(9-3-1)20-12-6-13-21(16-20)24-17-27-25(26-24)23-15-7-11-19-10-4-5-14-22(19)23/h1-17H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>3.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))
BDBM393740
PNG
(US10597367, Example 30 | US9969726, Example 30)
Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1cccc2ccccc12
Show InChI InChI=1S/C25H17NS/c1-2-8-18(9-3-1)20-12-6-13-21(16-20)24-17-27-25(26-24)23-15-7-11-19-10-4-5-14-22(19)23/h1-17H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>3.00E+4n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...


J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair
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