Compile Data Set for Download or QSAR

Found 229 hits Enz. Inhib. hit(s) with all data for entry = 3385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398264 (US10323018, Compound I-1) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCCc1cncn1C)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H24ClN5O/c1-3-4-21-20-10-7-17(24(31)27-12-11-19-14-26-15-30(19)2)13-22(20)29-23(28-21)16-5-8-18(25)9-6-16/h5-10,13-15H,3-4,11-12H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398265 (US10323018, Compound I-2) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1cncn1C)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-3-31-23-13-21(16-4-7-18(25)8-5-16)28-22-12-17(6-9-20(22)23)24(30)27-11-10-19-14-26-15-29(19)2/h4-9,12-15H,3,10-11H2,1-2H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398267 (US10323018, Compound I-4) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H24ClN5O/c1-2-4-20-19-11-8-17(24(31)28-12-3-5-22-26-13-14-27-22)15-21(19)30-23(29-20)16-6-9-18(25)10-7-16/h6-11,13-15H,2-5,12H2,1H3,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398268 (US10323018, Compound I-5) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN5O2/c1-2-31-21-13-19(15-5-8-17(24)9-6-15)28-20-12-16(7-10-18(20)21)23(30)25-11-3-4-22-26-14-27-29-22/h5-10,12-14H,2-4,11H2,1H3,(H,25,30)(H,26,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398274 (US10323018, Compound I-8) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCc1ccc2nccn2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H22ClN5O/c1-2-3-22-21-10-7-19(14-23(21)31-25(30-22)18-5-8-20(27)9-6-18)26(33)29-15-17-4-11-24-28-12-13-32(24)16-17/h4-14,16H,2-3,15H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398275 (US10323018, Compound I-9) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCc1nc2ccncc2[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H21ClN6O/c1-2-3-19-18-9-6-16(12-21(18)32-24(31-19)15-4-7-17(26)8-5-15)25(33)28-14-23-29-20-10-11-27-13-22(20)30-23/h4-13H,2-3,14H2,1H3,(H,28,33)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398276 (US10323018, Compound I-10) Show SMILES COc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H20ClN5O2/c1-30-22-17-9-6-15(21(29)26-10-2-3-19-24-11-12-25-19)13-18(17)27-20(28-22)14-4-7-16(23)8-5-14/h4-9,11-13H,2-3,10H2,1H3,(H,24,25)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398277 (US10323018, Compound I-11) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1cc(Cl)ccc1F Show InChI InChI=1S/C24H22ClFN4O2/c1-2-32-22-14-21(18-13-16(25)6-8-19(18)26)30-20-12-15(5-7-17(20)22)24(31)29-9-3-4-23-27-10-11-28-23/h5-8,10-14H,2-4,9H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398278 (US10323018, Compound I-12) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1cc(OC)ncc1F Show InChI InChI=1S/C24H24FN5O3/c1-3-33-21-13-20(17-12-23(32-2)29-14-18(17)25)30-19-11-15(6-7-16(19)21)24(31)28-8-4-5-22-26-9-10-27-22/h6-7,9-14H,3-5,8H2,1-2H3,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398279 (US10323018, Compound I-13) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN4O2/c1-2-31-22-15-20(16-5-8-18(25)9-6-16)29-21-14-17(7-10-19(21)22)24(30)28-11-3-4-23-26-12-13-27-23/h5-10,12-15H,2-4,11H2,1H3,(H,26,27)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398280 (US10323018, Compound I-14) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H20FN5O2/c1-2-33-23-12-20(15-3-6-17(26)7-4-15)29-21-11-16(5-8-18(21)23)25(32)28-14-24-30-19-9-10-27-13-22(19)31-24/h3-13H,2,14H2,1H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398281 (US10323018, Compound I-15) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-2-31-22-15-20(16-5-8-18(25)9-6-16)29-21-14-17(7-10-19(21)22)24(30)28-11-3-4-23-26-12-13-27-23/h5-10,12-15H,2-4,11H2,1H3,(H,26,27)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398282 (US10323018, Compound I-16) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H24FN5O/c1-2-4-20-19-11-8-17(24(31)28-12-3-5-22-26-13-14-27-22)15-21(19)30-23(29-20)16-6-9-18(25)10-7-16/h6-11,13-15H,2-5,12H2,1H3,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398288 (US10323018, Compound I-17) Show SMILES CC(C)Oc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O2/c1-16(2)32-23-15-21(17-5-8-19(26)9-6-17)30-22-14-18(7-10-20(22)23)25(31)29-11-3-4-24-27-12-13-28-24/h5-10,12-16H,3-4,11H2,1-2H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398290 (US10323018, Compound I-19) Show SMILES CCOc1nc(nc2cc(ccc12)C(=O)NCCCc1cncnc1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H22FN5O2/c1-2-32-24-20-10-7-18(23(31)28-11-3-4-16-13-26-15-27-14-16)12-21(20)29-22(30-24)17-5-8-19(25)9-6-17/h5-10,12-15H,2-4,11H2,1H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398295 (US10323018, Compound I-24) Show SMILES CCCc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)s1 Show InChI InChI=1S/C22H22ClN5OS/c1-2-4-16-15-7-6-14(22(29)26-10-3-5-20-24-11-12-25-20)13-17(15)28-21(27-16)18-8-9-19(23)30-18/h6-9,11-13H,2-5,10H2,1H3,(H,24,25)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398296 (US10323018, Compound I-25) Show SMILES COCc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H22ClN5O2/c1-31-14-20-18-9-6-16(23(30)27-10-2-3-21-25-11-12-26-21)13-19(18)28-22(29-20)15-4-7-17(24)8-5-15/h4-9,11-13H,2-3,10,14H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398298 (US10323018, Compound I-27) Show SMILES CCSc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN5OS/c1-2-31-23-18-10-7-16(22(30)27-11-3-4-20-25-12-13-26-20)14-19(18)28-21(29-23)15-5-8-17(24)9-6-15/h5-10,12-14H,2-4,11H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398299 (US10323018, Compound I-28) Show SMILES CCOc1nc(nc2cc(ccc12)C(=O)NCc1ccc2nccn2c1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H18ClN5O2S/c1-2-31-23-16-5-4-15(11-17(16)27-21(28-23)18-6-7-19(24)32-18)22(30)26-12-14-3-8-20-25-9-10-29(20)13-14/h3-11,13H,2,12H2,1H3,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398300 (US10323018, Compound I-29) Show SMILES CCOc1nc(nc2cc(ccc12)C(=O)NCCCc1ccnnc1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H22FN5O2/c1-2-32-24-20-10-7-18(23(31)26-12-3-4-16-11-13-27-28-15-16)14-21(20)29-22(30-24)17-5-8-19(25)9-6-17/h5-11,13-15H,2-4,12H2,1H3,(H,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398303 (US10323018, Compound I-32) Show SMILES CCOc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN5O2/c1-2-31-23-18-10-7-16(22(30)27-11-3-4-20-25-12-13-26-20)14-19(18)28-21(29-23)15-5-8-17(24)9-6-15/h5-10,12-14H,2-4,11H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398305 (US10323018, Compound I-34) Show SMILES CCOc1nc(nc2cc(ccc12)C(=O)NCc1ccc2nccn2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H20FN5O2/c1-2-33-25-20-9-6-18(13-21(20)29-23(30-25)17-4-7-19(26)8-5-17)24(32)28-14-16-3-10-22-27-11-12-31(22)15-16/h3-13,15H,2,14H2,1H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398306 (US10323018, Compound I-35) Show SMILES CCOc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)s1 Show InChI InChI=1S/C21H20ClN5O2S/c1-2-29-21-14-6-5-13(20(28)25-9-3-4-18-23-10-11-24-18)12-15(14)26-19(27-21)16-7-8-17(22)30-16/h5-8,10-12H,2-4,9H2,1H3,(H,23,24)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398307 (US10323018, Compound I-36) Show SMILES CC(C)Oc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H24FN5O2/c1-15(2)32-24-19-10-7-17(23(31)28-11-3-4-21-26-12-13-27-21)14-20(19)29-22(30-24)16-5-8-18(25)9-6-16/h5-10,12-15H,3-4,11H2,1-2H3,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398308 (US10323018, Compound I-37) Show SMILES COCCOc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H24FN5O3/c1-32-13-14-33-24-19-9-6-17(23(31)28-10-2-3-21-26-11-12-27-21)15-20(19)29-22(30-24)16-4-7-18(25)8-5-16/h4-9,11-12,15H,2-3,10,13-14H2,1H3,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398309 (US10323018, Compound I-38) Show SMILES CCOc1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H22ClN5O2/c1-2-31-23-18-10-7-16(22(30)27-11-3-4-20-25-12-13-26-20)14-19(18)28-21(29-23)15-5-8-17(24)9-6-15/h5-10,12-14H,2-4,11H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398311 (US10323018, Compound I-40) Show SMILES Fc1ccc(cc1)-c1nc(OCC2CC2)c2ccc(cc2n1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C25H24FN5O2/c26-19-8-5-17(6-9-19)23-30-21-14-18(24(32)29-11-1-2-22-27-12-13-28-22)7-10-20(21)25(31-23)33-15-16-3-4-16/h5-10,12-14,16H,1-4,11,15H2,(H,27,28)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398314 (US10323018, Compound I-43) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCn1cccn1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-2-31-23-16-21(17-5-8-19(25)9-6-17)28-22-15-18(7-10-20(22)23)24(30)26-11-3-13-29-14-4-12-27-29/h4-10,12,14-16H,2-3,11,13H2,1H3,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398315 (US10323018, Compound I-44) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nccs1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H22FN3O2S/c1-2-30-22-15-20(16-5-8-18(25)9-6-16)28-21-14-17(7-10-19(21)22)24(29)27-11-3-4-23-26-12-13-31-23/h5-10,12-15H,2-4,11H2,1H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398316 (US10323018, Compound I-45) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ccnnc1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H23FN4O2/c1-2-32-24-15-22(18-5-8-20(26)9-6-18)30-23-14-19(7-10-21(23)24)25(31)27-12-3-4-17-11-13-28-29-16-17/h5-11,13-16H,2-4,12H2,1H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398318 (US10323018, Compound I-47) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1ccc(cc1)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C27H22FN3O2/c1-2-33-26-16-24(20-7-10-22(28)11-8-20)31-25-15-21(9-12-23(25)26)27(32)30-14-13-18-3-5-19(17-29)6-4-18/h3-12,15-16H,2,13-14H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398320 (US10323018, Compound I-49) Show SMILES CCOc1cc(SCC)nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C20H24N4O2S/c1-3-26-17-13-19(27-4-2)24-16-12-14(7-8-15(16)17)20(25)23-9-5-6-18-21-10-11-22-18/h7-8,10-13H,3-6,9H2,1-2H3,(H,21,22)(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398321 (US10323018, Compound I-50 | US10323018, Compound I...) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCC1CC1c1ncc[nH]1)-c1ccc(F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398323 (US10323018, Compound I-52) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C24H22F2N4O2/c1-2-32-22-14-20(15-6-8-18(25)19(26)12-15)30-21-13-16(5-7-17(21)22)24(31)29-9-3-4-23-27-10-11-28-23/h5-8,10-14H,2-4,9H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398325 (US10323018, Compound I-54) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2ccccc2[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H21FN4O2/c1-2-33-24-14-22(16-7-10-18(27)11-8-16)29-23-13-17(9-12-19(23)24)26(32)28-15-25-30-20-5-3-4-6-21(20)31-25/h3-14H,2,15H2,1H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398327 (US10323018, Compound I-56) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C24H22ClFN4O2/c1-2-32-22-14-20(15-6-8-19(26)18(25)12-15)30-21-13-16(5-7-17(21)22)24(31)29-9-3-4-23-27-10-11-28-23/h5-8,10-14H,2-4,9H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398328 (US10323018, Compound I-57) Show SMILES Fc1ccc(cc1)-c1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H21ClFN5O/c28-20-8-3-18(4-9-20)26-33-23-16-19(27(35)32-13-1-2-24-30-14-15-31-24)7-12-22(23)25(34-26)17-5-10-21(29)11-6-17/h3-12,14-16H,1-2,13H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398331 (US10323018, Compound I-60) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NC1CC(C1)c1ncc[nH]1)-c1ccc(F)cc1 |(6.52,-3.08,;5.19,-3.85,;3.85,-3.08,;3.85,-1.54,;5.19,-.77,;5.19,.77,;3.85,1.54,;2.52,.77,;1.18,1.54,;-.15,.77,;-.15,-.77,;1.18,-1.54,;2.52,-.77,;-1.48,1.54,;-1.48,3.08,;-2.82,.77,;-4.15,1.54,;-5.48,.77,;-6.82,1.54,;-5.48,2.31,;-8.15,.77,;-9.62,1.25,;-10.52,,;-9.62,-1.25,;-8.15,-.77,;6.52,1.54,;7.85,.77,;9.19,1.54,;9.19,3.08,;10.52,3.85,;7.85,3.85,;6.52,3.08,)| Show InChI InChI=1S/C25H23FN4O2/c1-2-32-23-14-21(15-3-6-18(26)7-4-15)30-22-13-16(5-8-20(22)23)25(31)29-19-11-17(12-19)24-27-9-10-28-24/h3-10,13-14,17,19H,2,11-12H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398332 (US10323018, Compound I-61) Show SMILES CCOc1cc(OCC)c2ccc(cc2n1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C20H24N4O3/c1-3-26-17-13-19(27-4-2)24-16-12-14(7-8-15(16)17)20(25)23-9-5-6-18-21-10-11-22-18/h7-8,10-13H,3-6,9H2,1-2H3,(H,21,22)(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398341 (US10323018, Compound I-70) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccnc(OC)c1 Show InChI InChI=1S/C25H22N6O3/c1-3-34-22-13-20(17-6-8-26-24(12-17)33-2)30-21-11-18(4-5-19(21)22)25(32)27-14-16-7-9-31-23(10-16)28-15-29-31/h4-13,15H,3,14H2,1-2H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398343 (US10323018, Compound I-72) Show SMILES CC[C@@H](F)c1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(Cl)cc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398344 (US10323018, Compound I-73) Show SMILES CCOc1c(F)c(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H21F2N5O2/c1-2-32-22-18-10-7-15(23(31)26-11-3-4-17-13-27-30-29-17)12-19(18)28-21(20(22)25)14-5-8-16(24)9-6-14/h5-10,12-13H,2-4,11H2,1H3,(H,26,31)(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398345 (US10323018, Compound I-74) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccc2ncnn2c1)-c1ccnc(C)c1 Show InChI InChI=1S/C25H22N6O2/c1-3-33-23-12-21(18-8-9-26-16(2)10-18)30-22-11-19(5-6-20(22)23)25(32)27-13-17-4-7-24-28-15-29-31(24)14-17/h4-12,14-15H,3,13H2,1-2H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398349 (US10323018, Compound I-78) Show SMILES CCOc1c(F)c(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H21F2N5O2/c1-2-32-22-17-10-7-15(23(31)26-11-3-4-19-27-13-28-30-19)12-18(17)29-21(20(22)25)14-5-8-16(24)9-6-14/h5-10,12-13H,2-4,11H2,1H3,(H,26,31)(H,27,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398350 (US10323018, Compound I-79) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1cc2cnccc2s1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H20FN3O2S/c1-2-32-24-13-22(16-3-6-19(27)7-4-16)30-23-12-17(5-8-21(23)24)26(31)29-15-20-11-18-14-28-10-9-25(18)33-20/h3-14H,2,15H2,1H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398351 (US10323018, Compound I-80) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1cc2[nH]ncc2s1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H19FN4O2S/c1-2-31-22-11-19(14-3-6-16(25)7-4-14)28-20-9-15(5-8-18(20)22)24(30)26-12-17-10-21-23(32-17)13-27-29-21/h3-11,13H,2,12H2,1H3,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398353 (US10323018, Compound I-82) Show SMILES COCCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H22FN5O3/c1-34-10-11-35-24-14-22(18-2-5-20(27)6-3-18)31-23-13-19(4-7-21(23)24)26(33)28-15-17-8-9-32-25(12-17)29-16-30-32/h2-9,12-14,16H,10-11,15H2,1H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398355 (US10323018, Compound I-84) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccc2ncnn2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H20FN5O2/c1-2-33-23-12-21(17-4-7-19(26)8-5-17)30-22-11-18(6-9-20(22)23)25(32)27-13-16-3-10-24-28-15-29-31(24)14-16/h3-12,14-15H,2,13H2,1H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398356 (US10323018, Compound I-85) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccc(F)cc1OC Show InChI InChI=1S/C26H22FN5O3/c1-3-35-24-13-22(19-7-5-18(27)12-23(19)34-2)31-21-11-17(4-6-20(21)24)26(33)28-14-16-8-9-32-25(10-16)29-15-30-32/h4-13,15H,3,14H2,1-2H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398357 (US10323018, Compound I-86) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccnc(C)c1 Show InChI InChI=1S/C25H22N6O2/c1-3-33-23-13-21(18-6-8-26-16(2)10-18)30-22-12-19(4-5-20(22)23)25(32)27-14-17-7-9-31-24(11-17)28-15-29-31/h4-13,15H,3,14H2,1-2H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 229 total )  |  Next  |  Last  >>

Jump to: