Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50001820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378185 (CHEMBL4162688) Show SMILES CC(NCCC(Cc1ccccc1)c1ccco1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClNO/c1-17(19-9-11-21(23)12-10-19)24-14-13-20(22-8-5-15-25-22)16-18-6-3-2-4-7-18/h2-12,15,17,20,24H,13-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378188 (CHEMBL4177293) Show SMILES CC(NCCC(c1ccco1)c1ccc(F)cc1)c1ccc(C)cc1 Show InChI InChI=1S/C22H24FNO/c1-16-5-7-18(8-6-16)17(2)24-14-13-21(22-4-3-15-25-22)19-9-11-20(23)12-10-19/h3-12,15,17,21,24H,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378186 (CHEMBL4174981) Show SMILES FC(F)(F)C1(Nc2ccccn2)N=C(N(Cc2ccccc2)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C22H17F3N4O/c23-22(24,25)21(27-18-13-7-8-14-26-18)20(30)29(15-16-9-3-1-4-10-16)19(28-21)17-11-5-2-6-12-17/h1-14H,15H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378183 (CHEMBL4174845) Show SMILES COc1ccc(CNCCC(c2ccco2)c2ccccc2OC)cc1 Show InChI InChI=1S/C22H25NO3/c1-24-18-11-9-17(10-12-18)16-23-14-13-20(22-8-5-15-26-22)19-6-3-4-7-21(19)25-2/h3-12,15,20,23H,13-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378190 (CHEMBL4164143) Show SMILES CC(NCCC(c1ccco1)c1ccc(C)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClNO/c1-16-5-7-19(8-6-16)21(22-4-3-15-25-22)13-14-24-17(2)18-9-11-20(23)12-10-18/h3-12,15,17,21,24H,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378189 (CHEMBL4164250) Show SMILES COc1cc(CNCCC2=CCCCC2)ccc1OCc1ccccc1 |t:9| Show InChI InChI=1S/C23H29NO2/c1-25-23-16-21(17-24-15-14-19-8-4-2-5-9-19)12-13-22(23)26-18-20-10-6-3-7-11-20/h3,6-8,10-13,16,24H,2,4-5,9,14-15,17-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378184 (CHEMBL4175296) Show SMILES CCC1(C)CC(CCNCc2ccc(OC)c(OC)c2)(CCO1)c1ccc(C)cc1 Show InChI InChI=1S/C26H37NO3/c1-6-25(3)19-26(14-16-30-25,22-10-7-20(2)8-11-22)13-15-27-18-21-9-12-23(28-4)24(17-21)29-5/h7-12,17,27H,6,13-16,18-19H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378181 (CHEMBL4166667) Show SMILES CC(NCc1cc(Br)ccc1OCc1ccc(C)cc1)c1ccccc1 Show InChI InChI=1S/C23H24BrNO/c1-17-8-10-19(11-9-17)16-26-23-13-12-22(24)14-21(23)15-25-18(2)20-6-4-3-5-7-20/h3-14,18,25H,15-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM61471 ((3-Benzo[1,3]dioxol-5-yl-3-phenyl-propyl)-(4-metho...) Show SMILES COc1ccc(CNCCC(c2ccccc2)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C24H25NO3/c1-26-21-10-7-18(8-11-21)16-25-14-13-22(19-5-3-2-4-6-19)20-9-12-23-24(15-20)28-17-27-23/h2-12,15,22,25H,13-14,16-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378185 (CHEMBL4162688) Show SMILES CC(NCCC(Cc1ccccc1)c1ccco1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClNO/c1-17(19-9-11-21(23)12-10-19)24-14-13-20(22-8-5-15-25-22)16-18-6-3-2-4-7-18/h2-12,15,17,20,24H,13-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378189 (CHEMBL4164250) Show SMILES COc1cc(CNCCC2=CCCCC2)ccc1OCc1ccccc1 |t:9| Show InChI InChI=1S/C23H29NO2/c1-25-23-16-21(17-24-15-14-19-8-4-2-5-9-19)12-13-22(23)26-18-20-10-6-3-7-11-20/h3,6-8,10-13,16,24H,2,4-5,9,14-15,17-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378181 (CHEMBL4166667) Show SMILES CC(NCc1cc(Br)ccc1OCc1ccc(C)cc1)c1ccccc1 Show InChI InChI=1S/C23H24BrNO/c1-17-8-10-19(11-9-17)16-26-23-13-12-22(24)14-21(23)15-25-18(2)20-6-4-3-5-7-20/h3-14,18,25H,15-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378187 (CHEMBL4170813) Show SMILES CCC1(C)CC(CCNCc2ccccc2)(CCO1)c1ccc(C)cc1 Show InChI InChI=1S/C24H33NO/c1-4-23(3)19-24(15-17-26-23,22-12-10-20(2)11-13-22)14-16-25-18-21-8-6-5-7-9-21/h5-13,25H,4,14-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378182 (CHEMBL4160177) Show SMILES CC(CC(C)(C)c1ccc(C)o1)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H24F3NO/c1-13(11-18(3,4)17-10-5-14(2)24-17)23-12-15-6-8-16(9-7-15)19(20,21)22/h5-10,13,23H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378183 (CHEMBL4174845) Show SMILES COc1ccc(CNCCC(c2ccco2)c2ccccc2OC)cc1 Show InChI InChI=1S/C22H25NO3/c1-24-18-11-9-17(10-12-18)16-23-14-13-20(22-8-5-15-26-22)19-6-3-4-7-21(19)25-2/h3-12,15,20,23H,13-14,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378182 (CHEMBL4160177) Show SMILES CC(CC(C)(C)c1ccc(C)o1)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H24F3NO/c1-13(11-18(3,4)17-10-5-14(2)24-17)23-12-15-6-8-16(9-7-15)19(20,21)22/h5-10,13,23H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378188 (CHEMBL4177293) Show SMILES CC(NCCC(c1ccco1)c1ccc(F)cc1)c1ccc(C)cc1 Show InChI InChI=1S/C22H24FNO/c1-16-5-7-18(8-6-16)17(2)24-14-13-21(22-4-3-15-25-22)19-9-11-20(23)12-10-19/h3-12,15,17,21,24H,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378185 (CHEMBL4162688) Show SMILES CC(NCCC(Cc1ccccc1)c1ccco1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClNO/c1-17(19-9-11-21(23)12-10-19)24-14-13-20(22-8-5-15-25-22)16-18-6-3-2-4-7-18/h2-12,15,17,20,24H,13-14,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378189 (CHEMBL4164250) Show SMILES COc1cc(CNCCC2=CCCCC2)ccc1OCc1ccccc1 |t:9| Show InChI InChI=1S/C23H29NO2/c1-25-23-16-21(17-24-15-14-19-8-4-2-5-9-19)12-13-22(23)26-18-20-10-6-3-7-11-20/h3,6-8,10-13,16,24H,2,4-5,9,14-15,17-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378190 (CHEMBL4164143) Show SMILES CC(NCCC(c1ccco1)c1ccc(C)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClNO/c1-16-5-7-19(8-6-16)21(22-4-3-15-25-22)13-14-24-17(2)18-9-11-20(23)12-10-18/h3-12,15,17,21,24H,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50378180 (CHEMBL4166092) Show SMILES O[C@H](CCN1CCc2onc(c2C1)-c1ccc(F)c(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C21H20F2N2O2/c22-17-7-6-15(12-18(17)23)21-16-13-25(11-9-20(16)27-24-21)10-8-19(26)14-4-2-1-3-5-14/h1-7,12,19,26H,8-11,13H2/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378190 (CHEMBL4164143) Show SMILES CC(NCCC(c1ccco1)c1ccc(C)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24ClNO/c1-16-5-7-19(8-6-16)21(22-4-3-15-25-22)13-14-24-17(2)18-9-11-20(23)12-10-18/h3-12,15,17,21,24H,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378187 (CHEMBL4170813) Show SMILES CCC1(C)CC(CCNCc2ccccc2)(CCO1)c1ccc(C)cc1 Show InChI InChI=1S/C24H33NO/c1-4-23(3)19-24(15-17-26-23,22-12-10-20(2)11-13-22)14-16-25-18-21-8-6-5-7-9-21/h5-13,25H,4,14-19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378183 (CHEMBL4174845) Show SMILES COc1ccc(CNCCC(c2ccco2)c2ccccc2OC)cc1 Show InChI InChI=1S/C22H25NO3/c1-24-18-11-9-17(10-12-18)16-23-14-13-20(22-8-5-15-26-22)19-6-3-4-7-21(19)25-2/h3-12,15,20,23H,13-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378188 (CHEMBL4177293) Show SMILES CC(NCCC(c1ccco1)c1ccc(F)cc1)c1ccc(C)cc1 Show InChI InChI=1S/C22H24FNO/c1-16-5-7-18(8-6-16)17(2)24-14-13-21(22-4-3-15-25-22)19-9-11-20(23)12-10-19/h3-12,15,17,21,24H,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM61471 ((3-Benzo[1,3]dioxol-5-yl-3-phenyl-propyl)-(4-metho...) Show SMILES COc1ccc(CNCCC(c2ccccc2)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C24H25NO3/c1-26-21-10-7-18(8-11-21)16-25-14-13-22(19-5-3-2-4-6-19)20-9-12-23-24(15-20)28-17-27-23/h2-12,15,22,25H,13-14,16-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM61471 ((3-Benzo[1,3]dioxol-5-yl-3-phenyl-propyl)-(4-metho...) Show SMILES COc1ccc(CNCCC(c2ccccc2)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C24H25NO3/c1-26-21-10-7-18(8-11-21)16-25-14-13-22(19-5-3-2-4-6-19)20-9-12-23-24(15-20)28-17-27-23/h2-12,15,22,25H,13-14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378182 (CHEMBL4160177) Show SMILES CC(CC(C)(C)c1ccc(C)o1)NCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H24F3NO/c1-13(11-18(3,4)17-10-5-14(2)24-17)23-12-15-6-8-16(9-7-15)19(20,21)22/h5-10,13,23H,11-12H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378184 (CHEMBL4175296) Show SMILES CCC1(C)CC(CCNCc2ccc(OC)c(OC)c2)(CCO1)c1ccc(C)cc1 Show InChI InChI=1S/C26H37NO3/c1-6-25(3)19-26(14-16-30-25,22-10-7-20(2)8-11-22)13-15-27-18-21-9-12-23(28-4)24(17-21)29-5/h7-12,17,27H,6,13-16,18-19H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.68E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378184 (CHEMBL4175296) Show SMILES CCC1(C)CC(CCNCc2ccc(OC)c(OC)c2)(CCO1)c1ccc(C)cc1 Show InChI InChI=1S/C26H37NO3/c1-6-25(3)19-26(14-16-30-25,22-10-7-20(2)8-11-22)13-15-27-18-21-9-12-23(28-4)24(17-21)29-5/h7-12,17,27H,6,13-16,18-19H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.72E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378187 (CHEMBL4170813) Show SMILES CCC1(C)CC(CCNCc2ccccc2)(CCO1)c1ccc(C)cc1 Show InChI InChI=1S/C24H33NO/c1-4-23(3)19-24(15-17-26-23,22-12-10-20(2)11-13-22)14-16-25-18-21-8-6-5-7-9-21/h5-13,25H,4,14-19H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	4.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378180 (CHEMBL4166092) Show SMILES O[C@H](CCN1CCc2onc(c2C1)-c1ccc(F)c(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C21H20F2N2O2/c22-17-7-6-15(12-18(17)23)21-16-13-25(11-9-20(16)27-24-21)10-8-19(26)14-4-2-1-3-5-14/h1-7,12,19,26H,8-11,13H2/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.12E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50378186 (CHEMBL4174981) Show SMILES FC(F)(F)C1(Nc2ccccn2)N=C(N(Cc2ccccc2)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C22H17F3N4O/c23-22(24,25)21(27-18-13-7-8-14-26-18)20(30)29(15-16-9-3-1-4-10-16)19(28-21)17-11-5-2-6-12-17/h1-14H,15H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378181 (CHEMBL4166667) Show SMILES CC(NCc1cc(Br)ccc1OCc1ccc(C)cc1)c1ccccc1 Show InChI InChI=1S/C23H24BrNO/c1-17-8-10-19(11-9-17)16-26-23-13-12-22(24)14-21(23)15-25-18(2)20-6-4-3-5-7-20/h3-14,18,25H,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.96E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378186 (CHEMBL4174981) Show SMILES FC(F)(F)C1(Nc2ccccn2)N=C(N(Cc2ccccc2)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C22H17F3N4O/c23-22(24,25)21(27-18-13-7-8-14-26-18)20(30)29(15-16-9-3-1-4-10-16)19(28-21)17-11-5-2-6-12-17/h1-14H,15H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.84E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50378180 (CHEMBL4166092) Show SMILES O[C@H](CCN1CCc2onc(c2C1)-c1ccc(F)c(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C21H20F2N2O2/c22-17-7-6-15(12-18(17)23)21-16-13-25(11-9-20(16)27-24-21)10-8-19(26)14-4-2-1-3-5-14/h1-7,12,19,26H,8-11,13H2/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta TopCount analysis				Eur J Med Chem 151: 797-814 (2018) Article DOI: 10.1016/j.ejmech.2018.04.010 BindingDB Entry DOI: 10.7270/Q2W098H4
					More data for this Ligand-Target Pair