BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50001942
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride \| M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018933 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES C[C@H]1CCC[C@@](C1)(N1CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018932 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES C[C@@H]1CCC[C@@](C1)(N1CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018929 (3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCN(C1)C1(CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018929 (3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES CC1CCCN(C1)C1(CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Inhibition activity against binding of phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018931 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES C[C@H]1CCC[C@](C1)(N1CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018930 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine \| CHEM...) Show SMILES C[C@@H]1CCC[C@](C1)(N1CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride \| M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
National Institute of Diabetes Curated by ChEMBL					More data for this Ligand-Target Pair