Found 35 hits Enz. Inhib. hit(s) with all data for entry = 50001976 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50451425
(CHEMBL4212439)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-10-18-19(27-6-8-32-9-7-27)24-17(14-29(18)25-16)15-11-22-20(21)23-12-15/h10-12,14H,2-9,13H2,1H3,(H2,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 0.990 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of full-length human P110alpha (1 to 1068 residues)/N-terminal GST-fused p85alpha (1 to 724 residues) expressed in baculovirus expression ... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50451423
(CHEMBL4217392)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-24-18-17(27-6-8-32-9-7-27)23-15(12-29(18)25-16)14-10-21-19(20)22-11-14/h10-12H,2-9,13H2,1H3,(H2,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of full-length human P110alpha (1 to 1068 residues)/N-terminal GST-fused p85alpha (1 to 724 residues) expressed in baculovirus expression ... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50451426
(CHEMBL4208064)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3nc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)12-15-13-29-18(23-15)17(27-6-8-32-9-7-27)24-16(25-29)14-10-21-19(20)22-11-14/h10-11,13H,2-9,12H2,1H3,(H2,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of full-length human P110alpha (1 to 1068 residues)/N-terminal GST-fused p85alpha (1 to 724 residues) expressed in baculovirus expression ... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50451427
(CHEMBL4212973)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(c(Cl)n3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H26ClN9O3S/c1-34(31,32)29-4-2-27(3-5-29)13-15-10-16-19(28-6-8-33-9-7-28)25-17(18(21)30(16)26-15)14-11-23-20(22)24-12-14/h10-12H,2-9,13H2,1H3,(H2,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of full-length human P110alpha (1 to 1068 residues)/N-terminal GST-fused p85alpha (1 to 724 residues) expressed in baculovirus expression ... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50420714
(CHEMBL2087474)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3cc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)29-4-2-26(3-5-29)12-16-13-28-14-17(15-10-22-20(21)23-11-15)25-19(18(28)24-16)27-6-8-32-9-7-27/h10-11,13-14H,2-9,12H2,1H3,(H2,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of full-length human P110alpha (1 to 1068 residues)/N-terminal GST-fused p85alpha (1 to 724 residues) expressed in baculovirus expression ... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50451424
(CHEMBL4205584)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(-c4cnc(N)nc4)c(Cl)n3n2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H25ClN10O3S/c1-34(31,32)29-4-2-27(3-5-29)12-14-24-18-17(28-6-8-33-9-7-28)25-15(16(20)30(18)26-14)13-10-22-19(21)23-11-13/h10-11H,2-9,12H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/human full-length p85alpha expressed in baculovirus infected Sf21 insect... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50451424
(CHEMBL4205584)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(-c4cnc(N)nc4)c(Cl)n3n2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H25ClN10O3S/c1-34(31,32)29-4-2-27(3-5-29)12-14-24-18-17(28-6-8-33-9-7-28)25-15(16(20)30(18)26-14)13-10-22-19(21)23-11-13/h10-11H,2-9,12H2,1H3,(H2,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of full-length human P110alpha (1 to 1068 residues)/N-terminal GST-fused p85alpha (1 to 724 residues) expressed in baculovirus expression ... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50451423
(CHEMBL4217392)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-24-18-17(27-6-8-32-9-7-27)23-15(12-29(18)25-16)14-10-21-19(20)22-11-14/h10-12H,2-9,13H2,1H3,(H2,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/human full-length p85alpha expressed in baculovirus infected Sf21 insect... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50451425
(CHEMBL4212439)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-10-18-19(27-6-8-32-9-7-27)24-17(14-29(18)25-16)15-11-22-20(21)23-12-15/h10-12,14H,2-9,13H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/human full-length p85alpha expressed in baculovirus infected Sf21 insect... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50451427
(CHEMBL4212973)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(c(Cl)n3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H26ClN9O3S/c1-34(31,32)29-4-2-27(3-5-29)13-15-10-16-19(28-6-8-33-9-7-28)25-17(18(21)30(16)26-15)14-11-23-20(22)24-12-14/h10-12H,2-9,13H2,1H3,(H2,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/human full-length p85alpha expressed in baculovirus infected Sf21 insect... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50420714
(CHEMBL2087474)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3cc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)29-4-2-26(3-5-29)12-16-13-28-14-17(15-10-22-20(21)23-11-15)25-19(18(28)24-16)27-6-8-32-9-7-27/h10-11,13-14H,2-9,12H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/human full-length p85alpha expressed in baculovirus infected Sf21 insect... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM50451427
(CHEMBL4212973)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(c(Cl)n3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H26ClN9O3S/c1-34(31,32)29-4-2-27(3-5-29)13-15-10-16-19(28-6-8-33-9-7-28)25-17(18(21)30(16)26-15)14-11-23-20(22)24-12-14/h10-12H,2-9,13H2,1H3,(H2,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant full-length human N-terminal His6-tagged p110gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50451426
(CHEMBL4208064)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3nc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)12-15-13-29-18(23-15)17(27-6-8-32-9-7-27)24-16(25-29)14-10-21-19(20)22-11-14/h10-11,13H,2-9,12H2,1H3,(H2,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full-length N-terminal His6-tagged p110delta/human full-length p85alpha expressed in baculovirus infected Sf21 insect... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM50451423
(CHEMBL4217392)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-24-18-17(27-6-8-32-9-7-27)23-15(12-29(18)25-16)14-10-21-19(20)22-11-14/h10-12H,2-9,13H2,1H3,(H2,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant full-length human N-terminal His6-tagged p110gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM50451426
(CHEMBL4208064)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3nc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)12-15-13-29-18(23-15)17(27-6-8-32-9-7-27)24-16(25-29)14-10-21-19(20)22-11-14/h10-11,13H,2-9,12H2,1H3,(H2,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant full-length human N-terminal His6-tagged p110gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM50451424
(CHEMBL4205584)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(-c4cnc(N)nc4)c(Cl)n3n2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H25ClN10O3S/c1-34(31,32)29-4-2-27(3-5-29)12-14-24-18-17(28-6-8-33-9-7-28)25-15(16(20)30(18)26-14)13-10-22-19(21)23-11-13/h10-11H,2-9,12H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant full-length human N-terminal His6-tagged p110gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50451425
(CHEMBL4212439)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-10-18-19(27-6-8-32-9-7-27)24-17(14-29(18)25-16)15-11-22-20(21)23-12-15/h10-12,14H,2-9,13H2,1H3,(H2,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
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PC cid
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UniChem
| Article
PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of p110beta/85alpha (unknown origin) using PIP2 as substrate by HTRF assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM50451425
(CHEMBL4212439)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-10-18-19(27-6-8-32-9-7-27)24-17(14-29(18)25-16)15-11-22-20(21)23-12-15/h10-12,14H,2-9,13H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant full-length human N-terminal His6-tagged p110gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50451427
(CHEMBL4212973)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(c(Cl)n3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H26ClN9O3S/c1-34(31,32)29-4-2-27(3-5-29)13-15-10-16-19(28-6-8-33-9-7-28)25-17(18(21)30(16)26-15)14-11-23-20(22)24-12-14/h10-12H,2-9,13H2,1H3,(H2,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of p110beta/85alpha (unknown origin) using PIP2 as substrate by HTRF assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50451423
(CHEMBL4217392)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-24-18-17(27-6-8-32-9-7-27)23-15(12-29(18)25-16)14-10-21-19(20)22-11-14/h10-12H,2-9,13H2,1H3,(H2,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 155 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of p110beta/85alpha (unknown origin) using PIP2 as substrate by HTRF assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50420714
(CHEMBL2087474)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3cc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)29-4-2-26(3-5-29)12-16-13-28-14-17(15-10-22-20(21)23-11-15)25-19(18(28)24-16)27-6-8-32-9-7-27/h10-11,13-14H,2-9,12H2,1H3,(H2,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of p110beta/85alpha (unknown origin) using PIP2 as substrate by HTRF assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM50420714
(CHEMBL2087474)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3cc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)29-4-2-26(3-5-29)12-16-13-28-14-17(15-10-22-20(21)23-11-15)25-19(18(28)24-16)27-6-8-32-9-7-27/h10-11,13-14H,2-9,12H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 179 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant full-length human N-terminal His6-tagged p110gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substr... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50451424
(CHEMBL4205584)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(-c4cnc(N)nc4)c(Cl)n3n2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H25ClN10O3S/c1-34(31,32)29-4-2-27(3-5-29)12-14-24-18-17(28-6-8-33-9-7-28)25-15(16(20)30(18)26-14)13-10-22-19(21)23-11-13/h10-11H,2-9,12H2,1H3,(H2,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 285 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of p110beta/85alpha (unknown origin) using PIP2 as substrate by HTRF assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50451426
(CHEMBL4208064)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3nc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)12-15-13-29-18(23-15)17(27-6-8-32-9-7-27)24-16(25-29)14-10-21-19(20)22-11-14/h10-11,13H,2-9,12H2,1H3,(H2,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 388 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of p110beta/85alpha (unknown origin) using PIP2 as substrate by HTRF assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human)) | BDBM50451423
(CHEMBL4217392)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-24-18-17(27-6-8-32-9-7-27)23-15(12-29(18)25-16)14-10-21-19(20)22-11-14/h10-12H,2-9,13H2,1H3,(H2,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system by AlexaFluor647-... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human)) | BDBM50451425
(CHEMBL4212439)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-10-18-19(27-6-8-32-9-7-27)24-17(14-29(18)25-16)15-11-22-20(21)23-12-15/h10-12,14H,2-9,13H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system by AlexaFluor647-... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human)) | BDBM50451426
(CHEMBL4208064)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3nc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)12-15-13-29-18(23-15)17(27-6-8-32-9-7-27)24-16(25-29)14-10-21-19(20)22-11-14/h10-11,13H,2-9,12H2,1H3,(H2,20,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system by AlexaFluor647-... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human)) | BDBM50420714
(CHEMBL2087474)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3cc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)29-4-2-26(3-5-29)12-16-13-28-14-17(15-10-22-20(21)23-11-15)25-19(18(28)24-16)27-6-8-32-9-7-27/h10-11,13-14H,2-9,12H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system by AlexaFluor647-... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human)) | BDBM50451427
(CHEMBL4212973)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(c(Cl)n3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H26ClN9O3S/c1-34(31,32)29-4-2-27(3-5-29)13-15-10-16-19(28-6-8-33-9-7-28)25-17(18(21)30(16)26-15)14-11-23-20(22)24-12-14/h10-12H,2-9,13H2,1H3,(H2,22,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system by AlexaFluor647-... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human)) | BDBM50451424
(CHEMBL4205584)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(-c4cnc(N)nc4)c(Cl)n3n2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H25ClN10O3S/c1-34(31,32)29-4-2-27(3-5-29)12-14-24-18-17(28-6-8-33-9-7-28)25-15(16(20)30(18)26-14)13-10-22-19(21)23-11-13/h10-11H,2-9,12H2,1H3,(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system by AlexaFluor647-... |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50451425
(CHEMBL4212439)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H27N9O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-10-18-19(27-6-8-32-9-7-27)24-17(14-29(18)25-16)15-11-22-20(21)23-12-15/h10-12,14H,2-9,13H2,1H3,(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by Tracer Red dye based fluorescence polarization assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50451423
(CHEMBL4217392)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(cn3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)13-16-24-18-17(27-6-8-32-9-7-27)23-15(12-29(18)25-16)14-10-21-19(20)22-11-14/h10-12H,2-9,13H2,1H3,(H2,20,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by Tracer Red dye based fluorescence polarization assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50451424
(CHEMBL4205584)Show SMILES CS(=O)(=O)N1CCN(Cc2nc3c(nc(-c4cnc(N)nc4)c(Cl)n3n2)N2CCOCC2)CC1 Show InChI InChI=1S/C19H25ClN10O3S/c1-34(31,32)29-4-2-27(3-5-29)12-14-24-18-17(28-6-8-33-9-7-28)25-15(16(20)30(18)26-14)13-10-22-19(21)23-11-13/h10-11H,2-9,12H2,1H3,(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by Tracer Red dye based fluorescence polarization assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50451427
(CHEMBL4212973)Show SMILES CS(=O)(=O)N1CCN(Cc2cc3c(nc(c(Cl)n3n2)-c2cnc(N)nc2)N2CCOCC2)CC1 Show InChI InChI=1S/C20H26ClN9O3S/c1-34(31,32)29-4-2-27(3-5-29)13-15-10-16-19(28-6-8-33-9-7-28)25-17(18(21)30(16)26-15)14-11-23-20(22)24-12-14/h10-12H,2-9,13H2,1H3,(H2,22,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by Tracer Red dye based fluorescence polarization assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50451426
(CHEMBL4208064)Show SMILES CS(=O)(=O)N1CCN(Cc2cn3nc(nc(N4CCOCC4)c3n2)-c2cnc(N)nc2)CC1 Show InChI InChI=1S/C19H26N10O3S/c1-33(30,31)28-4-2-26(3-5-28)12-15-13-29-18(23-15)17(27-6-8-32-9-7-27)24-16(25-29)14-10-21-19(20)22-11-14/h10-11,13H,2-9,12H2,1H3,(H2,20,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Spanish National Cancer Research Centre (CNIO)
Curated by ChEMBL
| Assay Description
Inhibition of human ERG by Tracer Red dye based fluorescence polarization assay |
Bioorg Med Chem Lett 27: 4794-4799 (2017)
Article DOI: 10.1016/j.bmcl.2017.09.059
BindingDB Entry DOI: 10.7270/Q2F76G4X |
More data for this
Ligand-Target Pair | |
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