Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with all data for entry = 50002664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461301 (CHEMBL4227475) Show SMILES Cl.Cl.CC(C)[C@H]1c2ccc(F)cc2CC[C@@]1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C1CC1 |r| Show InChI InChI=1S/C30H38FN3O2.2ClH/c1-20(2)28-24-13-12-23(31)19-22(24)14-15-30(28,36-29(35)21-10-11-21)16-18-34(3)17-6-9-27-32-25-7-4-5-8-26(25)33-27;;/h4-5,7-8,12-13,19-21,28H,6,9-11,14-18H2,1-3H3,(H,32,33);2*1H/t28-,30-;;/m0../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461301 (CHEMBL4227475) Show SMILES Cl.Cl.CC(C)[C@H]1c2ccc(F)cc2CC[C@@]1(CCN(C)CCCc1nc2ccccc2[nH]1)OC(=O)C1CC1 |r| Show InChI InChI=1S/C30H38FN3O2.2ClH/c1-20(2)28-24-13-12-23(31)19-22(24)14-15-30(28,36-29(35)21-10-11-21)16-18-34(3)17-6-9-27-32-25-7-4-5-8-26(25)33-27;;/h4-5,7-8,12-13,19-21,28H,6,9-11,14-18H2,1-3H3,(H,32,33);2*1H/t28-,30-;;/m0../s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461289 (MK-6721 | NMED-160 | NP-118809 | Z-160 | Z160) Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30,32H,21-25H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461288 (CHEMBL4226804) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CNc2nc3ccc(Oc4ccc(F)cc4)cc3s2)cc1 Show InChI InChI=1S/C25H26FN3O2S/c1-29(2)14-3-15-30-20-8-4-18(5-9-20)17-27-25-28-23-13-12-22(16-24(23)32-25)31-21-10-6-19(26)7-11-21/h4-13,16H,3,14-15,17H2,1-2H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461297 (CHEMBL4226823) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C#N)cc3s2)cc1 Show InChI InChI=1S/C26H26N4O2S/c1-30(2)14-3-15-31-21-8-6-20(7-9-21)18-28-26-29-24-13-12-23(16-25(24)33-26)32-22-10-4-19(17-27)5-11-22/h4-13,16H,3,14-15,18H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461290 (CHEMBL4229218) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C#N)cc3s2)cc1 Show InChI InChI=1S/C24H22N4O2S/c25-12-1-13-29-19-6-4-18(5-7-19)16-27-24-28-22-11-10-21(14-23(22)31-24)30-20-8-2-17(15-26)3-9-20/h2-11,14H,1,12-13,16,25H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461289 (MK-6721 | NMED-160 | NP-118809 | Z-160 | Z160) Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30,32H,21-25H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461292 (CHEMBL4226674) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CN(C)c2nc3ccc(Oc4ccc(cc4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C27H28F3N3O2S/c1-32(2)15-4-16-34-21-9-5-19(6-10-21)18-33(3)26-31-24-14-13-23(17-25(24)36-26)35-22-11-7-20(8-12-22)27(28,29)30/h5-14,17H,4,15-16,18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461282 (CHEMBL4225603) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccccc3)cc2s1 Show InChI InChI=1S/C24H25N3O2S/c1-27(17-18-8-10-19(11-9-18)28-15-5-14-25)24-26-22-13-12-21(16-23(22)30-24)29-20-6-3-2-4-7-20/h2-4,6-13,16H,5,14-15,17,25H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461296 (CHEMBL4227653) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CNc2nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C26H26F3N3O2S/c1-32(2)13-4-14-33-20-9-7-18(8-10-20)17-30-25-31-23-12-11-22(16-24(23)35-25)34-21-6-3-5-19(15-21)26(27,28)29/h3,5-12,15-16H,4,13-14,17H2,1-2H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461292 (CHEMBL4226674) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CN(C)c2nc3ccc(Oc4ccc(cc4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C27H28F3N3O2S/c1-32(2)15-4-16-34-21-9-5-19(6-10-21)18-33(3)26-31-24-14-13-23(17-25(24)36-26)35-22-11-7-20(8-12-22)27(28,29)30/h5-14,17H,4,15-16,18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461278 (CHEMBL4227740) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C24H22F3N3O2S/c25-24(26,27)17-4-8-19(9-5-17)32-20-10-11-21-22(14-20)33-23(30-21)29-15-16-2-6-18(7-3-16)31-13-1-12-28/h2-11,14H,1,12-13,15,28H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461276 (CHEMBL4227450) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CN(C)c2nc3ccc(Oc4ccc(cc4)C#N)cc3s2)cc1 Show InChI InChI=1S/C27H28N4O2S/c1-30(2)15-4-16-32-22-9-7-21(8-10-22)19-31(3)27-29-25-14-13-24(17-26(25)34-27)33-23-11-5-20(18-28)6-12-23/h5-14,17H,4,15-16,19H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461284 (CHEMBL4226597) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccc(cc3)C#N)cc2s1 Show InChI InChI=1S/C25H24N4O2S/c1-29(17-19-5-7-20(8-6-19)30-14-2-13-26)25-28-23-12-11-22(15-24(23)32-25)31-21-9-3-18(16-27)4-10-21/h3-12,15H,2,13-14,17,26H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461276 (CHEMBL4227450) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CN(C)c2nc3ccc(Oc4ccc(cc4)C#N)cc3s2)cc1 Show InChI InChI=1S/C27H28N4O2S/c1-30(2)15-4-16-32-22-9-7-21(8-10-22)19-31(3)27-29-25-14-13-24(17-26(25)34-27)33-23-11-5-20(18-28)6-12-23/h5-14,17H,4,15-16,19H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461283 (CHEMBL4225757) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3cccc(c3)C(F)(F)F)cc2s1 Show InChI InChI=1S/C25H24F3N3O2S/c1-31(16-17-6-8-19(9-7-17)32-13-3-12-29)24-30-22-11-10-21(15-23(22)34-24)33-20-5-2-4-18(14-20)25(26,27)28/h2,4-11,14-15H,3,12-13,16,29H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461282 (CHEMBL4225603) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccccc3)cc2s1 Show InChI InChI=1S/C24H25N3O2S/c1-27(17-18-8-10-19(11-9-18)28-15-5-14-25)24-26-22-13-12-21(16-23(22)30-24)29-20-6-3-2-4-7-20/h2-4,6-13,16H,5,14-15,17,25H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461275 (CHEMBL4226924) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C24H24FN3O2S/c1-28(16-17-3-7-19(8-4-17)29-14-2-13-26)24-27-22-12-11-21(15-23(22)31-24)30-20-9-5-18(25)6-10-20/h3-12,15H,2,13-14,16,26H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461291 (CHEMBL4225227) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCNC(N)=N)cc1)c1nc2ccc(Oc3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C25H26FN5O2S/c1-31(16-17-3-7-19(8-4-17)32-14-2-13-29-24(27)28)25-30-22-12-11-21(15-23(22)34-25)33-20-9-5-18(26)6-10-20/h3-12,15H,2,13-14,16H2,1H3,(H4,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461299 (CHEMBL4225787) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccccc4)cc3s2)cc1 Show InChI InChI=1S/C24H25N5O2S/c25-23(26)27-13-4-14-30-18-9-7-17(8-10-18)16-28-24-29-21-12-11-20(15-22(21)32-24)31-19-5-2-1-3-6-19/h1-3,5-12,15H,4,13-14,16H2,(H,28,29)(H4,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461297 (CHEMBL4226823) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C#N)cc3s2)cc1 Show InChI InChI=1S/C26H26N4O2S/c1-30(2)14-3-15-31-21-8-6-20(7-9-21)18-28-26-29-24-13-12-23(16-25(24)33-26)32-22-10-4-19(17-27)5-11-22/h4-13,16H,3,14-15,18H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461298 (CHEMBL4228579) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(F)cc4)cc3s2)cc1 Show InChI InChI=1S/C23H22FN3O2S/c24-17-4-8-19(9-5-17)29-20-10-11-21-22(14-20)30-23(27-21)26-15-16-2-6-18(7-3-16)28-13-1-12-25/h2-11,14H,1,12-13,15,25H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461290 (CHEMBL4229218) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C#N)cc3s2)cc1 Show InChI InChI=1S/C24H22N4O2S/c25-12-1-13-29-19-6-4-18(5-7-19)16-27-24-28-22-11-10-21(14-23(22)31-24)30-20-8-2-17(15-26)3-9-20/h2-11,14H,1,12-13,16,25H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461296 (CHEMBL4227653) Show SMILES OC(=O)C(F)(F)F.CN(C)CCCOc1ccc(CNc2nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C26H26F3N3O2S/c1-32(2)13-4-14-33-20-9-7-18(8-10-20)17-30-25-31-23-12-11-22(16-24(23)35-25)34-21-6-3-5-19(15-21)26(27,28)29/h3,5-12,15-16H,4,13-14,17H2,1-2H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461278 (CHEMBL4227740) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C24H22F3N3O2S/c25-24(26,27)17-4-8-19(9-5-17)32-20-10-11-21-22(14-20)33-23(30-21)29-15-16-2-6-18(7-3-16)31-13-1-12-28/h2-11,14H,1,12-13,15,28H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461285 (CHEMBL4225492) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCNC(N)=N)cc1)c1nc2ccc(Oc3ccccc3)cc2s1 Show InChI InChI=1S/C25H27N5O2S/c1-30(17-18-8-10-19(11-9-18)31-15-5-14-28-24(26)27)25-29-22-13-12-21(16-23(22)33-25)32-20-6-3-2-4-7-20/h2-4,6-13,16H,5,14-15,17H2,1H3,(H4,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461302 (CHEMBL4224756) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccc(O)cc3)cc2s1 Show InChI InChI=1S/C24H25N3O3S/c1-27(16-17-3-7-19(8-4-17)29-14-2-13-25)24-26-22-12-11-21(15-23(22)31-24)30-20-9-5-18(28)6-10-20/h3-12,15,28H,2,13-14,16,25H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461300 (CHEMBL4225354) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C25H24F3N5O2S/c26-25(27,28)17-3-1-4-19(13-17)35-20-9-10-21-22(14-20)36-24(33-21)32-15-16-5-7-18(8-6-16)34-12-2-11-31-23(29)30/h1,3-10,13-14H,2,11-12,15H2,(H,32,33)(H4,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461287 (CHEMBL4225815) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCNC(N)=N)cc1)c1nc2ccc(Oc3ccc(cc3)C#N)cc2s1 Show InChI InChI=1S/C26H26N6O2S/c1-32(17-19-5-7-20(8-6-19)33-14-2-13-30-25(28)29)26-31-23-12-11-22(15-24(23)35-26)34-21-9-3-18(16-27)4-10-21/h3-12,15H,2,13-14,17H2,1H3,(H4,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.43E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461279 (CHEMBL4224750) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C24H22F3N3O2S/c25-24(26,27)17-3-1-4-19(13-17)32-20-9-10-21-22(14-20)33-23(30-21)29-15-16-5-7-18(8-6-16)31-12-2-11-28/h1,3-10,13-14H,2,11-12,15,28H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461287 (CHEMBL4225815) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCNC(N)=N)cc1)c1nc2ccc(Oc3ccc(cc3)C#N)cc2s1 Show InChI InChI=1S/C26H26N6O2S/c1-32(17-19-5-7-20(8-6-19)33-14-2-13-30-25(28)29)26-31-23-12-11-22(15-24(23)35-26)34-21-9-3-18(16-27)4-10-21/h3-12,15H,2,13-14,17H2,1H3,(H4,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.53E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461302 (CHEMBL4224756) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccc(O)cc3)cc2s1 Show InChI InChI=1S/C24H25N3O3S/c1-27(16-17-3-7-19(8-4-17)29-14-2-13-25)24-26-22-12-11-21(15-23(22)31-24)30-20-9-5-18(28)6-10-20/h3-12,15,28H,2,13-14,16,25H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461299 (CHEMBL4225787) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccccc4)cc3s2)cc1 Show InChI InChI=1S/C24H25N5O2S/c25-23(26)27-13-4-14-30-18-9-7-17(8-10-18)16-28-24-29-21-12-11-20(15-22(21)32-24)31-19-5-2-1-3-6-19/h1-3,5-12,15H,4,13-14,16H2,(H,28,29)(H4,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461293 (CHEMBL4225288) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C25H24F3N5O2S/c26-25(27,28)17-4-8-19(9-5-17)35-20-10-11-21-22(14-20)36-24(33-21)32-15-16-2-6-18(7-3-16)34-13-1-12-31-23(29)30/h2-11,14H,1,12-13,15H2,(H,32,33)(H4,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.67E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461279 (CHEMBL4224750) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C24H22F3N3O2S/c25-24(26,27)17-3-1-4-19(13-17)32-20-9-10-21-22(14-20)33-23(30-21)29-15-16-5-7-18(8-6-16)31-12-2-11-28/h1,3-10,13-14H,2,11-12,15,28H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.71E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461304 (CHEMBL4226080) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCNC(N)=N)cc1)c1nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2s1 Show InChI InChI=1S/C26H26F3N5O2S/c1-34(16-17-3-7-19(8-4-17)35-14-2-13-32-24(30)31)25-33-22-12-11-21(15-23(22)37-25)36-20-9-5-18(6-10-20)26(27,28)29/h3-12,15H,2,13-14,16H2,1H3,(H4,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.85E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461293 (CHEMBL4225288) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(cc4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C25H24F3N5O2S/c26-25(27,28)17-4-8-19(9-5-17)35-20-10-11-21-22(14-20)36-24(33-21)32-15-16-2-6-18(7-3-16)34-13-1-12-31-23(29)30/h2-11,14H,1,12-13,15H2,(H,32,33)(H4,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461286 (CHEMBL4224963) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCNC(N)=N)cc1)c1nc2ccc(Oc3cccc(c3)C(F)(F)F)cc2s1 Show InChI InChI=1S/C26H26F3N5O2S/c1-34(16-17-6-8-19(9-7-17)35-13-3-12-32-24(30)31)25-33-22-11-10-21(15-23(22)37-25)36-20-5-2-4-18(14-20)26(27,28)29/h2,4-11,14-15H,3,12-13,16H2,1H3,(H4,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461277 (CHEMBL4224809) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(O)cc4)cc3s2)cc1 Show InChI InChI=1S/C23H23N3O3S/c24-12-1-13-28-18-6-2-16(3-7-18)15-25-23-26-21-11-10-20(14-22(21)30-23)29-19-8-4-17(27)5-9-19/h2-11,14,27H,1,12-13,15,24H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461304 (CHEMBL4226080) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCNC(N)=N)cc1)c1nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2s1 Show InChI InChI=1S/C26H26F3N5O2S/c1-34(16-17-3-7-19(8-4-17)35-14-2-13-32-24(30)31)25-33-22-12-11-21(15-23(22)37-25)36-20-9-5-18(6-10-20)26(27,28)29/h3-12,15H,2,13-14,16H2,1H3,(H4,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50295700 (CHEMBL550448 | [4-(3-Amino-propoxy)-benzyl]-(6-phe...) Show SMILES NCCCOc1ccc(CNc2nc3ccc(Oc4ccccc4)cc3s2)cc1 Show InChI InChI=1S/C23H23N3O2S/c24-13-4-14-27-18-9-7-17(8-10-18)16-25-23-26-21-12-11-20(15-22(21)29-23)28-19-5-2-1-3-6-19/h1-3,5-12,15H,4,13-14,16,24H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.18E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461283 (CHEMBL4225757) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3cccc(c3)C(F)(F)F)cc2s1 Show InChI InChI=1S/C25H24F3N3O2S/c1-31(16-17-6-8-19(9-7-17)32-13-3-12-29)24-30-22-11-10-21(15-23(22)34-24)33-20-5-2-4-18(14-20)25(26,27)28/h2,4-11,14-15H,3,12-13,16,29H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461281 (CHEMBL4226136) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(F)cc4)cc3s2)cc1 Show InChI InChI=1S/C24H24FN5O2S/c25-17-4-8-19(9-5-17)32-20-10-11-21-22(14-20)33-24(30-21)29-15-16-2-6-18(7-3-16)31-13-1-12-28-23(26)27/h2-11,14H,1,12-13,15H2,(H,29,30)(H4,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461294 (CHEMBL4226078) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2s1 Show InChI InChI=1S/C25H24F3N3O2S/c1-31(16-17-3-7-19(8-4-17)32-14-2-13-29)24-30-22-12-11-21(15-23(22)34-24)33-20-9-5-18(6-10-20)25(26,27)28/h3-12,15H,2,13-14,16,29H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461280 (CHEMBL4225014) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(O)cc4)cc3s2)cc1 Show InChI InChI=1S/C24H25N5O3S/c25-23(26)27-12-1-13-31-18-6-2-16(3-7-18)15-28-24-29-21-11-10-20(14-22(21)33-24)32-19-8-4-17(30)5-9-19/h2-11,14,30H,1,12-13,15H2,(H,28,29)(H4,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.53E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461300 (CHEMBL4225354) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3s2)cc1 Show InChI InChI=1S/C25H24F3N5O2S/c26-25(27,28)17-3-1-4-19(13-17)35-20-9-10-21-22(14-20)36-24(33-21)32-15-16-5-7-18(8-6-16)34-12-2-11-31-23(29)30/h1,3-10,13-14H,2,11-12,15H2,(H,32,33)(H4,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50461294 (CHEMBL4226078) Show SMILES OC(=O)C(F)(F)F.CN(Cc1ccc(OCCCN)cc1)c1nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2s1 Show InChI InChI=1S/C25H24F3N3O2S/c1-31(16-17-3-7-19(8-4-17)32-14-2-13-29)24-30-22-12-11-21(15-23(22)34-24)33-20-9-5-18(6-10-20)25(26,27)28/h3-12,15H,2,13-14,16,29H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.83E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of Cav2.2 in human SH-SY5Y cells assessed as decrease in KCl-induced calcium mobilization measured after 600 secs post compound addition a...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461281 (CHEMBL4226136) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(F)cc4)cc3s2)cc1 Show InChI InChI=1S/C24H24FN5O2S/c25-17-4-8-19(9-5-17)32-20-10-11-21-22(14-20)33-24(30-21)29-15-16-2-6-18(7-3-16)31-13-1-12-28-23(26)27/h2-11,14H,1,12-13,15H2,(H,29,30)(H4,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.88E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461277 (CHEMBL4224809) Show SMILES OC(=O)C(F)(F)F.NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(O)cc4)cc3s2)cc1 Show InChI InChI=1S/C23H23N3O3S/c24-12-1-13-28-18-6-2-16(3-7-18)15-25-23-26-21-11-10-20(14-22(21)30-23)29-19-8-4-17(27)5-9-19/h2-11,14,27H,1,12-13,15,24H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50461280 (CHEMBL4225014) Show SMILES OC(=O)C(F)(F)F.NC(=N)NCCCOc1ccc(CNc2nc3ccc(Oc4ccc(O)cc4)cc3s2)cc1 Show InChI InChI=1S/C24H25N5O3S/c25-23(26)27-12-1-13-31-18-6-2-16(3-7-18)15-28-24-29-21-11-10-20(14-22(21)33-24)32-19-8-4-17(30)5-9-19/h2-11,14,30H,1,12-13,15H2,(H,28,29)(H4,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
IITB-Monash Research Academy Curated by ChEMBL					Assay Description Inhibition of recombinant human Cav3.2-alpha1 expressed in HEK293T cells assessed as decrease in KCl-induced calcium mobilization measured after 600 ...				Bioorg Med Chem 26: 3046-3059 (2018) Article DOI: 10.1016/j.bmc.2018.03.031 BindingDB Entry DOI: 10.7270/Q2BC4253
					More data for this Ligand-Target Pair

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