Compile Data Set for Download or QSAR

Found 11 hits Enz. Inhib. hit(s) with all data for entry = 50003019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50328731 (CHEMBL1269025 | Edoxaban) Show SMILES CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1 |r| Show InChI InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465847 (CHEMBL4278492) Show SMILES [H][C@]12CCC3=CC[C@@](C)(O)CC[C@@]3([H])[C@]1(C)C[C@@H](C[C@@]2(C)COC(C)=O)OC(C)=O |r,t:4| Show InChI InChI=1S/C23H36O5/c1-15(24)27-14-21(3)12-18(28-16(2)25)13-23(5)19-9-11-22(4,26)10-8-17(19)6-7-20(21)23/h8,18-20,26H,6-7,9-14H2,1-5H3/t18-,19-,20-,21+,22-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465844 (CHEMBL4293622) Show SMILES [H][C@@]12CC[C@@](C)(C=C1CC[C@]1([H])C(C)(C)[C@H](O)CC[C@@]21C)C1COC(C)(C)O1 |r,c:6| Show InChI InChI=1S/C23H38O3/c1-20(2)17-8-7-15-13-22(5,19-14-25-21(3,4)26-19)11-9-16(15)23(17,6)12-10-18(20)24/h13,16-19,24H,7-12,14H2,1-6H3/t16-,17-,18-,19?,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465846 (CHEMBL4289150) Show SMILES [H][C@@]12CC[C@](C)(CO)C=C1CC[C@]1([H])[C@](C)(COC(C)=O)C[C@H](C[C@@]21C)OC(C)=O |r,c:8| Show InChI InChI=1S/C23H36O5/c1-15(25)27-14-22(4)11-18(28-16(2)26)12-23(5)19-8-9-21(3,13-24)10-17(19)6-7-20(22)23/h10,18-20,24H,6-9,11-14H2,1-5H3/t18-,19-,20-,21+,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465842 (Kirenol) Show SMILES [H][C@@]12CC[C@@](C)(C=C1CC[C@]1([H])[C@](C)(CO)C[C@@H](O)C[C@@]21C)[C@@H](O)CO |r,c:6| Show InChI InChI=1S/C20H34O4/c1-18(17(24)11-21)7-6-15-13(8-18)4-5-16-19(2,12-22)9-14(23)10-20(15,16)3/h8,14-17,21-24H,4-7,9-12H2,1-3H3/t14-,15-,16-,17+,18+,19+,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465848 (CHEMBL4280434) Show SMILES [H][C@@]12CC[C@@](C)(C=C1CC[C@]1([H])C(C)(C)[C@@H](CC[C@@]21C)OC(C)=O)[C@@H](O)CO |r,c:6| Show InChI InChI=1S/C22H36O4/c1-14(24)26-19-9-11-22(5)16-8-10-21(4,18(25)13-23)12-15(16)6-7-17(22)20(19,2)3/h12,16-19,23,25H,6-11,13H2,1-5H3/t16-,17-,18+,19-,21+,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465843 (CHEMBL4292565) Show SMILES [H][C@@]12CC[C@@](C)(C=C1CC[C@]1([H])[C@](C)(COC(C)=O)C[C@H](C[C@@]21C)OC(C)=O)[C@@H](O)CO |r,c:6| Show InChI InChI=1S/C24H38O6/c1-15(26)29-14-23(4)11-18(30-16(2)27)12-24(5)19-8-9-22(3,21(28)13-25)10-17(19)6-7-20(23)24/h10,18-21,25,28H,6-9,11-14H2,1-5H3/t18-,19-,20-,21+,22+,23+,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465850 (CHEMBL4286054) Show SMILES [H][C@@]12CC[C@](C)(O)CC=C1CC[C@]1([H])C(C)(C)[C@@H](CC[C@@]21C)OC(C)=O |r,c:8| Show InChI InChI=1S/C21H34O3/c1-14(22)24-18-10-13-21(5)16-9-12-20(4,23)11-8-15(16)6-7-17(21)19(18,2)3/h8,16-18,23H,6-7,9-13H2,1-5H3/t16-,17-,18-,20-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465845 (CHEMBL3315237) Show SMILES [H][C@@]12CC[C@@](C)(C=C1CC[C@]1([H])[C@](C)(CO)C[C@@H](O)C[C@@]21C)C1COC(C)(C)O1 |r,c:6| Show InChI InChI=1S/C23H38O4/c1-20(2)26-13-19(27-20)21(3)9-8-17-15(10-21)6-7-18-22(4,14-24)11-16(25)12-23(17,18)5/h10,16-19,24-25H,6-9,11-14H2,1-5H3/t16-,17-,18-,19?,21+,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465849 (CHEMBL4293958) Show SMILES [H][C@@]12CC[C@](C)(CO)C=C1CC[C@]1([H])C(C)(C)[C@@H](CC[C@@]21C)OC(C)=O |r,c:8| Show InChI InChI=1S/C21H34O3/c1-14(23)24-18-9-11-21(5)16-8-10-20(4,13-22)12-15(16)6-7-17(21)19(18,2)3/h12,16-18,22H,6-11,13H2,1-5H3/t16-,17-,18-,20+,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50465851 (Darutigenol) Show SMILES [H][C@@]12CC[C@@](C)(C=C1CC[C@]1([H])C(C)(C)[C@H](O)CC[C@@]21C)[C@@H](O)CO |r,c:6| Show InChI InChI=1S/C20H34O3/c1-18(2)15-6-5-13-11-19(3,17(23)12-21)9-7-14(13)20(15,4)10-8-16(18)22/h11,14-17,21-23H,5-10,12H2,1-4H3/t14-,15-,16-,17+,19+,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...				Bioorg Med Chem Lett 28: 3813-3815 (2018) Article DOI: 10.1016/j.bmcl.2018.05.036 BindingDB Entry DOI: 10.7270/Q2WQ06GP
					More data for this Ligand-Target Pair