Compile Data Set for Download or QSAR

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50003044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50466167 (CHEMBL4278808) Show SMILES Oc1ccc(c(F)c1)-c1nc2ccc3[nH]ncc3c2c2CCCCc12 Show InChI InChI=1S/C20H16FN3O/c21-16-9-11(25)5-6-14(16)20-13-4-2-1-3-12(13)19-15-10-22-24-17(15)7-8-18(19)23-20/h5-10,25H,1-4H2,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of Haspin (unknown origin) after 3 hrs by ADP-Glo assay				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466158 (CHEMBL4290247) Show SMILES Fc1ccc(CC(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)cc1 Show InChI InChI=1S/C22H16FN3OS/c23-19-5-3-15(4-6-19)8-22(27)26-20-9-17(12-25-13-20)21-10-18(14-28-21)16-2-1-7-24-11-16/h1-7,9-14H,8H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466158 (CHEMBL4290247) Show SMILES Fc1ccc(CC(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)cc1 Show InChI InChI=1S/C22H16FN3OS/c23-19-5-3-15(4-6-19)8-22(27)26-20-9-17(12-25-13-20)21-10-18(14-28-21)16-2-1-7-24-11-16/h1-7,9-14H,8H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant human Dyrk1A expressed in Baculovirus expression system by Z'-LYTE assay				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466168 (CHEMBL4282366) Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C22H17N3OS/c26-22(9-16-5-2-1-3-6-16)25-20-10-18(13-24-14-20)21-11-19(15-27-21)17-7-4-8-23-12-17/h1-8,10-15H,9H2,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466164 (CHEMBL4283474) Show SMILES Fc1cc(F)c(C(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)c(F)c1 Show InChI InChI=1S/C21H12F3N3OS/c22-15-6-17(23)20(18(24)7-15)21(28)27-16-4-13(9-26-10-16)19-5-14(11-29-19)12-2-1-3-25-8-12/h1-11H,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase haspin (Homo sapiens (Human))	BDBM50466158 (CHEMBL4290247) Show SMILES Fc1ccc(CC(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)cc1 Show InChI InChI=1S/C22H16FN3OS/c23-19-5-3-15(4-6-19)8-22(27)26-20-9-17(12-25-13-20)21-10-18(14-28-21)16-2-1-7-24-11-16/h1-7,9-14H,8H2,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant human Haspin expressed in Baculovirus expression system by Adapta assay				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466157 (CHEMBL4294049) Show SMILES COc1ccc(C(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)c(F)c1 Show InChI InChI=1S/C22H16FN3O2S/c1-28-18-4-5-19(20(23)9-18)22(27)26-17-7-15(11-25-12-17)21-8-16(13-29-21)14-3-2-6-24-10-14/h2-13H,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466169 (CHEMBL4295177) Show SMILES Fc1ccc(C(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)c(F)c1 Show InChI InChI=1S/C21H13F2N3OS/c22-16-3-4-18(19(23)8-16)21(27)26-17-6-14(10-25-11-17)20-7-15(12-28-20)13-2-1-5-24-9-13/h1-12H,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466159 (CHEMBL4292471) Show SMILES Cc1ccc(cc1)C(=O)Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C22H17N3OS/c1-15-4-6-16(7-5-15)22(26)25-20-9-18(12-24-13-20)21-10-19(14-27-21)17-3-2-8-23-11-17/h2-14H,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466158 (CHEMBL4290247) Show SMILES Fc1ccc(CC(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)cc1 Show InChI InChI=1S/C22H16FN3OS/c23-19-5-3-15(4-6-19)8-22(27)26-20-9-17(12-25-13-20)21-10-18(14-28-21)16-2-1-7-24-11-16/h1-7,9-14H,8H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of Dyrk1A in human HeLa cells transfected with GFP-SF3b1-NT assessed as decrease in SF3B1 phosphorylation at Thr434 after 18 hrs by Wester...				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466162 (CHEMBL4291297) Show SMILES Clc1ccccc1C(=O)Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C21H14ClN3OS/c22-19-6-2-1-5-18(19)21(26)25-17-8-15(11-24-12-17)20-9-16(13-27-20)14-4-3-7-23-10-14/h1-13H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466161 (CHEMBL4281037) Show SMILES Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C14H11N3S/c15-13-4-11(7-17-8-13)14-5-12(9-18-14)10-2-1-3-16-6-10/h1-9H,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466171 (CHEMBL4290223) Show SMILES Fc1ccccc1C(=O)Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C21H14FN3OS/c22-19-6-2-1-5-18(19)21(26)25-17-8-15(11-24-12-17)20-9-16(13-27-20)14-4-3-7-23-10-14/h1-13H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466165 (CHEMBL4286821) Show SMILES O=C(Nc1cncc(c1)-c1cc(cs1)-c1cccnc1)c1ccncc1 Show InChI InChI=1S/C20H14N4OS/c25-20(14-3-6-21-7-4-14)24-18-8-16(11-23-12-18)19-9-17(13-26-19)15-2-1-5-22-10-15/h1-13H,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466170 (CHEMBL4282261) Show SMILES Nc1cncc(c1)-c1csc(c1)-c1cccnc1 Show InChI InChI=1S/C14H11N3S/c15-13-4-11(7-17-8-13)12-5-14(18-9-12)10-2-1-3-16-6-10/h1-9H,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466161 (CHEMBL4281037) Show SMILES Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C14H11N3S/c15-13-4-11(7-17-8-13)14-5-12(9-18-14)10-2-1-3-16-6-10/h1-9H,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466163 (CHEMBL4286803) Show SMILES Fc1ccc(cc1)C(=O)Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C21H14FN3OS/c22-18-5-3-14(4-6-18)21(26)25-19-8-16(11-24-12-19)20-9-17(13-27-20)15-2-1-7-23-10-15/h1-13H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466166 (CHEMBL4285559) Show SMILES Nc1ccc(cn1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C14H11N3S/c15-14-4-3-11(8-17-14)13-6-12(9-18-13)10-2-1-5-16-7-10/h1-9H,(H2,15,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466164 (CHEMBL4283474) Show SMILES Fc1cc(F)c(C(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)c(F)c1 Show InChI InChI=1S/C21H12F3N3OS/c22-15-6-17(23)20(18(24)7-15)21(28)27-16-4-13(9-26-10-16)19-5-14(11-29-19)12-2-1-3-25-8-12/h1-11H,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	299	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466160 (CHEMBL4280981) Show SMILES c1sc(cc1-c1cccnc1)-c1cccnc1 Show InChI InChI=1S/C14H10N2S/c1-3-11(8-15-5-1)13-7-14(17-10-13)12-4-2-6-16-9-12/h1-10H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466160 (CHEMBL4280981) Show SMILES c1sc(cc1-c1cccnc1)-c1cccnc1 Show InChI InChI=1S/C14H10N2S/c1-3-11(8-15-5-1)13-7-14(17-10-13)12-4-2-6-16-9-12/h1-10H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466168 (CHEMBL4282366) Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C22H17N3OS/c26-22(9-16-5-2-1-3-6-16)25-20-10-18(13-24-14-20)21-11-19(15-27-21)17-7-4-8-23-12-17/h1-8,10-15H,9H2,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	326	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466158 (CHEMBL4290247) Show SMILES Fc1ccc(CC(=O)Nc2cncc(c2)-c2cc(cs2)-c2cccnc2)cc1 Show InChI InChI=1S/C22H16FN3OS/c23-19-5-3-15(4-6-19)8-22(27)26-20-9-17(12-25-13-20)21-10-18(14-28-21)16-2-1-7-24-11-16/h1-7,9-14H,8H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	383	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50466166 (CHEMBL4285559) Show SMILES Nc1ccc(cn1)-c1cc(cs1)-c1cccnc1 Show InChI InChI=1S/C14H11N3S/c15-14-4-3-11(8-17-14)13-6-12(9-18-13)10-2-1-5-16-7-10/h1-9H,(H2,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	614	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATP				Eur J Med Chem 157: 1031-1050 (2018) Article DOI: 10.1016/j.ejmech.2018.07.050 BindingDB Entry DOI: 10.7270/Q2280B8Q
					More data for this Ligand-Target Pair