BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50003872
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476855 (CHEMBL232112) Show SMILES CNc1ccc(cc1)C#Cc1cnc(OCCO)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476850 (CHEMBL232114) Show SMILES OCCOc1ncc(cc1I)C#Cc1ccc(O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476852 (CHEMBL231917) Show SMILES CN(C)c1ccc(cc1)C#Cc1cnc(OCCO)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476848 (CHEMBL231916) Show SMILES CN(C)c1ccc(cc1)C#Cc1cnc(OCCO)c(I)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476853 (CHEMBL398059) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476851 (CHEMBL231918) Show SMILES CNc1ccc(cc1)C#Cc1cnc(OCCOCCOCCF)c(Br)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476854 (CHEMBL232113) Show SMILES CNc1ccc(cc1)C#Cc1cnc(OCCO)c(I)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476849 (CHEMBL231915) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [125I]IMPY from beta amyloid plaque in human brain homogenates				Bioorg Med Chem Lett 17: 3581-4 (2007) Article DOI: 10.1016/j.bmcl.2007.04.062 BindingDB Entry DOI: 10.7270/Q2QZ2DQX
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair