BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 28 hits Enz. Inhib. hit(s) with all data for entry = 50003916   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477491
PNG
(CHEMBL398034)
Show SMILES Clc1cccc(Cl)c1S(=O)(=O)N1CCOc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C18H19Cl2N3O3S/c19-13-3-1-4-14(20)18(13)27(24,25)23-11-12-26-17-15(5-2-6-16(17)23)22-9-7-21-8-10-22/h1-6,21H,7-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.0631n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477488
PNG
(CHEMBL394690)
Show SMILES COc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C19H22FN3O4S/c1-26-14-12-16(22-8-6-21-7-9-22)19-17(13-14)23(10-11-27-19)28(24,25)18-5-3-2-4-15(18)20/h2-5,12-13,21H,6-11H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.158n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477473
PNG
(CHEMBL246918)
Show SMILES CC1(C)CN(c2cccc(N3CCNCC3)c2O1)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C20H24FN3O3S/c1-20(2)14-24(28(25,26)18-9-4-3-6-15(18)21)17-8-5-7-16(19(17)27-20)23-12-10-22-11-13-23/h3-9,22H,10-14H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.316n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477475
PNG
(CHEMBL246499)
Show SMILES Cc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C19H22FN3O3S/c1-14-12-16(22-8-6-21-7-9-22)19-17(13-14)23(10-11-26-19)27(24,25)18-5-3-2-4-15(18)20/h2-5,12-13,21H,6-11H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.398n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477479
PNG
(CHEMBL246706)
Show SMILES COc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H23N3O4S/c1-25-15-13-17(21-9-7-20-8-10-21)19-18(14-15)22(11-12-26-19)27(23,24)16-5-3-2-4-6-16/h2-6,13-14,20H,7-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.398n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477489
PNG
(CHEMBL246705)
Show SMILES Fc1ccccc1S(=O)(=O)N1CCOc2c(cc(Cl)cc12)N1CCNCC1
Show InChI InChI=1S/C18H19ClFN3O3S/c19-13-11-15(22-7-5-21-6-8-22)18-16(12-13)23(9-10-26-18)27(24,25)17-4-2-1-3-14(17)20/h1-4,11-12,21H,5-10H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.398n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477477
PNG
(CHEMBL246291)
Show SMILES Clc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1cccc2nonc12
Show InChI InChI=1S/C18H18ClN5O4S/c19-12-10-14(23-6-4-20-5-7-23)18-15(11-12)24(8-9-27-18)29(25,26)16-3-1-2-13-17(16)22-28-21-13/h1-3,10-11,20H,4-9H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.501n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477497
PNG
(CHEMBL246498)
Show SMILES Clc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1cccc2cccnc12
Show InChI InChI=1S/C21H21ClN4O3S/c22-16-13-17(25-9-7-23-8-10-25)21-18(14-16)26(11-12-29-21)30(27,28)19-5-1-3-15-4-2-6-24-20(15)19/h1-6,13-14,23H,7-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.631n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477487
PNG
(CHEMBL246704)
Show SMILES Fc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C18H19F2N3O3S/c19-13-11-15(22-7-5-21-6-8-22)18-16(12-13)23(9-10-26-18)27(24,25)17-4-2-1-3-14(17)20/h1-4,11-12,21H,5-10H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.631n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477490
PNG
(CHEMBL394691)
Show SMILES Fc1ccccc1S(=O)(=O)N1CC2(CCC2)Oc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C21H24FN3O3S/c22-16-5-1-2-8-19(16)29(26,27)25-15-21(9-4-10-21)28-20-17(6-3-7-18(20)25)24-13-11-23-12-14-24/h1-3,5-8,23H,4,9-15H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.631n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477472
PNG
(CHEMBL398036)
Show SMILES Clc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H22ClN3O3S/c23-17-14-19(25-10-8-24-9-11-25)22-20(15-17)26(12-13-29-22)30(27,28)21-7-3-5-16-4-1-2-6-18(16)21/h1-7,14-15,24H,8-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
0.794n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477471
PNG
(CHEMBL246917)
Show SMILES Nc1ccc(cc1)S(=O)(=O)N1CCOc2c(cc(F)cc12)N1CCNCC1
Show InChI InChI=1S/C18H21FN4O3S/c19-13-11-16(22-7-5-21-6-8-22)18-17(12-13)23(9-10-26-18)27(24,25)15-3-1-14(20)2-4-15/h1-4,11-12,21H,5-10,20H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477483
PNG
(CHEMBL246078)
Show SMILES Fc1ccccc1S(=O)(=O)N1CCOc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C18H20FN3O3S/c19-14-4-1-2-7-17(14)26(23,24)22-12-13-25-18-15(5-3-6-16(18)22)21-10-8-20-9-11-21/h1-7,20H,8-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477494
PNG
(CHEMBL246079)
Show SMILES Clc1cccc(c1)S(=O)(=O)N1CCOc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C18H20ClN3O3S/c19-14-3-1-4-15(13-14)26(23,24)22-11-12-25-18-16(5-2-6-17(18)22)21-9-7-20-8-10-21/h1-6,13,20H,7-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
2n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477478
PNG
(CHEMBL246500)
Show SMILES Cc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1ccccc1C#N
Show InChI InChI=1S/C20H22N4O3S/c1-15-12-17(23-8-6-22-7-9-23)20-18(13-15)24(10-11-27-20)28(25,26)19-5-3-2-4-16(19)14-21/h2-5,12-13,22H,6-11H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
2n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477470
PNG
(CHEMBL394689)
Show SMILES Cc1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H23N3O3S/c1-15-13-17(21-9-7-20-8-10-21)19-18(14-15)22(11-12-25-19)26(23,24)16-5-3-2-4-6-16/h2-6,13-14,20H,7-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
2.5n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477492
PNG
(CHEMBL398035)
Show SMILES Clc1ccccc1S(=O)(=O)N1CCOc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C18H20ClN3O3S/c19-14-4-1-2-7-17(14)26(23,24)22-12-13-25-18-15(5-3-6-16(18)22)21-10-8-20-9-11-21/h1-7,20H,8-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
3.20n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477495
PNG
(CHEMBL394949)
Show SMILES Clc1cc2N(CCOc2c(c1)N1CCCNCC1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H22ClN3O3S/c20-15-13-17(22-9-4-7-21-8-10-22)19-18(14-15)23(11-12-26-19)27(24,25)16-5-2-1-3-6-16/h1-3,5-6,13-14,21H,4,7-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
4n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477474
PNG
(CHEMBL247121)
Show SMILES CC1(C)CN(c2cc(F)cc(C3CCNCC3)c2O1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C21H25FN2O3S/c1-21(2)14-24(28(25,26)17-6-4-3-5-7-17)19-13-16(22)12-18(20(19)27-21)15-8-10-23-11-9-15/h3-7,12-13,15,23H,8-11,14H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
4n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477496
PNG
(CHEMBL438675)
Show SMILES CC1(C)CN(c2cc(F)cc(C3CCNCC3)c2O1)S(=O)(=O)c1cccc(F)c1
Show InChI InChI=1S/C21H24F2N2O3S/c1-21(2)13-25(29(26,27)17-5-3-4-15(22)10-17)19-12-16(23)11-18(20(19)28-21)14-6-8-24-9-7-14/h3-5,10-12,14,24H,6-9,13H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
5n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477486
PNG
(CHEMBL246916)
Show SMILES CC(C)(C)c1cc(N2CCNCC2)c2OCCN(c2c1)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C22H28FN3O3S/c1-22(2,3)16-14-18(25-10-8-24-9-11-25)21-19(15-16)26(12-13-29-21)30(27,28)20-7-5-4-6-17(20)23/h4-7,14-15,24H,8-13H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
7.90n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477480
PNG
(CHEMBL246080)
Show SMILES Fc1cccc(c1)S(=O)(=O)N1CCOc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C18H20FN3O3S/c19-14-3-1-4-15(13-14)26(23,24)22-11-12-25-18-16(5-2-6-17(18)22)21-9-7-20-8-10-21/h1-6,13,20H,7-12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
10n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477493
PNG
(CHEMBL246077)
Show SMILES O=S(=O)(N1CCOc2c(cccc12)N1CCNCC1)c1ccccc1
Show InChI InChI=1S/C18H21N3O3S/c22-25(23,15-5-2-1-3-6-15)21-13-14-24-18-16(7-4-8-17(18)21)20-11-9-19-10-12-20/h1-8,19H,9-14H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
13n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477482
PNG
(CHEMBL247120)
Show SMILES CC1CN(CC(C)N1)c1cc(C)cc2N(CCOc12)S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H26ClN3O3S/c1-14-10-19(24-12-15(2)23-16(3)13-24)21-20(11-14)25(8-9-28-21)29(26,27)18-6-4-17(22)5-7-18/h4-7,10-11,15-16,23H,8-9,12-13H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
40n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477481
PNG
(CHEMBL247325)
Show SMILES CN(C)CCNc1cccc2N(CC(C)(C)Oc12)S(=O)(=O)c1cccc(F)c1
Show InChI InChI=1S/C20H26FN3O3S/c1-20(2)14-24(28(25,26)16-8-5-7-15(21)13-16)18-10-6-9-17(19(18)27-20)22-11-12-23(3)4/h5-10,13,22H,11-12,14H2,1-4H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
126n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477485
PNG
(CHEMBL246289)
Show SMILES CS(=O)(=O)Nc1cccc(c1)S(=O)(=O)N1CCOc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C19H24N4O5S2/c1-29(24,25)21-15-4-2-5-16(14-15)30(26,27)23-12-13-28-19-17(6-3-7-18(19)23)22-10-8-20-9-11-22/h2-7,14,20-21H,8-13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
200n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477476
PNG
(CHEMBL246290)
Show SMILES CS(=O)(=O)c1ccccc1S(=O)(=O)N1CCOc2c(cccc12)N1CCNCC1
Show InChI InChI=1S/C19H23N3O5S2/c1-28(23,24)17-7-2-3-8-18(17)29(25,26)22-13-14-27-19-15(5-4-6-16(19)22)21-11-9-20-10-12-21/h2-8,20H,9-14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
316n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50477484
PNG
(CHEMBL247119)
Show SMILES Nc1cccc2N(CCOc12)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C14H13FN2O3S/c15-10-4-1-2-7-13(10)21(18,19)17-8-9-20-14-11(16)5-3-6-12(14)17/h1-7H,8-9,16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
631n/an/an/an/an/an/an/an/a



Roche Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3504-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.093
BindingDB Entry DOI: 10.7270/Q29P34FX
More data for this
Ligand-Target Pair