Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with all data for entry = 50003965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50478130 (CHEMBL271159) Show SMILES [H][C@]12CC[C@](C)(O)[C@@H](Cc3cc(O)ccc3O)[C@]1(C)CC[C@]1([H])[C@]3(C)CCC[C@]21COC3=O Show InChI InChI=1S/C26H36O5/c1-23-11-7-20-24(2)9-4-10-26(20,15-31-22(24)29)19(23)8-12-25(3,30)21(23)14-16-13-17(27)5-6-18(16)28/h5-6,13,19-21,27-28,30H,4,7-12,14-15H2,1-3H3/t19-,20+,21-,23+,24-,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 transcriptional activation in human U251-HRE cells by luciferase reporter assay				J Med Chem 51: 1402-5 (2008) Article DOI: 10.1021/jm7010854 BindingDB Entry DOI: 10.7270/Q2W95CZS
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50478132 (CHEMBL259472) Show SMILES [H][C@]12CC[C@]3(C)[C@]([H])(CC[C@]4(C)Oc5ccc(O)cc5C[C@@]34[H])[C@@]1(C)CCC[C@]2(C)C(O)=O Show InChI InChI=1S/C26H36O4/c1-23-10-5-11-25(3,22(28)29)20(23)8-12-24(2)19(23)9-13-26(4)21(24)15-16-14-17(27)6-7-18(16)30-26/h6-7,14,19-21,27H,5,8-13,15H2,1-4H3,(H,28,29)/t19-,20+,21+,23-,24-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 transcriptional activation in human U251-HRE cells by luciferase reporter assay				J Med Chem 51: 1402-5 (2008) Article DOI: 10.1021/jm7010854 BindingDB Entry DOI: 10.7270/Q2W95CZS
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50478131 (CHEMBL270091) Show SMILES [H][C@]12CC[C@]3(C)[C@]([H])(CC[C@]4(C)Oc5ccc(O)cc5C[C@@]34[H])[C@@]11CCC[C@]2(C)C(=O)OC1 Show InChI InChI=1S/C26H34O4/c1-23-11-7-20-24(2)9-4-10-26(20,15-29-22(24)28)19(23)8-12-25(3)21(23)14-16-13-17(27)5-6-18(16)30-25/h5-6,13,19-21,27H,4,7-12,14-15H2,1-3H3/t19-,20+,21-,23+,24-,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1 transcriptional activation in human U251-HRE cells by luciferase reporter assay				J Med Chem 51: 1402-5 (2008) Article DOI: 10.1021/jm7010854 BindingDB Entry DOI: 10.7270/Q2W95CZS
					More data for this Ligand-Target Pair