Found 29 hits Enz. Inhib. hit(s) with all data for entry = 50004442 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482992
(CHEMBL1269927)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C25H20FN5O2/c1-31(15-16-10-11-21-18(14-16)12-13-33-21)24-28-23(29-25(32)30-24)27-22-19(8-5-9-20(22)26)17-6-3-2-4-7-17/h2-14H,15H2,1H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase protein
(Human immunodeficiency virus 1) | BDBM50482992
(CHEMBL1269927)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C25H20FN5O2/c1-31(15-16-10-11-21-18(14-16)12-13-33-21)24-28-23(29-25(32)30-24)27-22-19(8-5-9-20(22)26)17-6-3-2-4-7-17/h2-14H,15H2,1H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 reverse transcriptase L100I mutant |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482991
(CHEMBL1270036)Show SMILES CN(Cc1ccc2OCCc2c1)c1nc(O)nc(Nc2c(C)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C26H25N5O2/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)27-24-28-25(30-26(32)29-24)31(2)16-18-11-12-22-20(15-18)13-14-33-22/h3-12,15H,13-14,16H2,1-2H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483013
(CHEMBL1271250)Show SMILES Cc1cccc(-c2ccccc2)c1Nc1nc(O)nc(NCc2ccc3occc3c2)n1 Show InChI InChI=1S/C25H21N5O2/c1-16-6-5-9-20(18-7-3-2-4-8-18)22(16)27-24-28-23(29-25(31)30-24)26-15-17-10-11-21-19(14-17)12-13-32-21/h2-14H,15H2,1H3,(H3,26,27,28,29,30,31) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase protein
(Human immunodeficiency virus 1) | BDBM50482991
(CHEMBL1270036)Show SMILES CN(Cc1ccc2OCCc2c1)c1nc(O)nc(Nc2c(C)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C26H25N5O2/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)27-24-28-25(30-26(32)29-24)31(2)16-18-11-12-22-20(15-18)13-14-33-22/h3-12,15H,13-14,16H2,1-2H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 reverse transcriptase L100I mutant |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482996
(CHEMBL1269928)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(F)cc(F)cc2-c2ccccc2)n1 Show InChI InChI=1S/C25H19F2N5O2/c1-32(14-15-7-8-21-17(11-15)9-10-34-21)24-29-23(30-25(33)31-24)28-22-19(12-18(26)13-20(22)27)16-5-3-2-4-6-16/h2-13H,14H2,1H3,(H2,28,29,30,31,33) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483007
(CHEMBL1270035)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(C)cccc2-c2ccoc2)n1 Show InChI InChI=1S/C24H21N5O3/c1-15-4-3-5-19(18-8-10-31-14-18)21(15)25-22-26-23(28-24(30)27-22)29(2)13-16-6-7-20-17(12-16)9-11-32-20/h3-12,14H,13H2,1-2H3,(H2,25,26,27,28,30) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483008
(CHEMBL1271460)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(C)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C26H23N5O2/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)27-24-28-25(30-26(32)29-24)31(2)16-18-11-12-22-20(15-18)13-14-33-22/h3-15H,16H2,1-2H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482995
(CHEMBL1270141)Show SMILES CN(Cc1ccc2OCOc2c1)c1nc(O)nc(Nc2c(C)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C25H23N5O3/c1-16-7-6-10-19(18-8-4-3-5-9-18)22(16)26-23-27-24(29-25(31)28-23)30(2)14-17-11-12-20-21(13-17)33-15-32-20/h3-13H,14-15H2,1-2H3,(H2,26,27,28,29,31) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483009
(CHEMBL1271251)Show SMILES Oc1nc(NCc2ccc3occc3c2)nc(Nc2c(F)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C24H18FN5O2/c25-19-8-4-7-18(16-5-2-1-3-6-16)21(19)27-23-28-22(29-24(31)30-23)26-14-15-9-10-20-17(13-15)11-12-32-20/h1-13H,14H2,(H3,26,27,28,29,30,31) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483001
(CHEMBL1271043)Show SMILES Cc1cccc(-c2ccccc2)c1Nc1nc(O)nc(NCc2ccc3cc[nH]c3c2)n1 Show InChI InChI=1S/C25H22N6O/c1-16-6-5-9-20(18-7-3-2-4-8-18)22(16)28-24-29-23(30-25(32)31-24)27-15-17-10-11-19-12-13-26-21(19)14-17/h2-14,26H,15H2,1H3,(H3,27,28,29,30,31,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482993
(CHEMBL1270346)Show SMILES COc1nc(NCc2ccc3occc3c2)nc(Nc2c(C)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C26H23N5O2/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)28-25-29-24(30-26(31-25)32-2)27-16-18-11-12-22-20(15-18)13-14-33-22/h3-15H,16H2,1-2H3,(H2,27,28,29,30,31) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483003
(CHEMBL1270839)Show SMILES Oc1nc(NCc2ccc3cc[nH]c3c2)nc(Nc2ccccc2-c2ccccc2)n1 Show InChI InChI=1S/C24H20N6O/c31-24-29-22(26-15-16-10-11-18-12-13-25-21(18)14-16)28-23(30-24)27-20-9-5-4-8-19(20)17-6-2-1-3-7-17/h1-14,25H,15H2,(H3,26,27,28,29,30,31) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482998
(CHEMBL1271352)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2ccccc2N2CCOCC2)n1 Show InChI InChI=1S/C23H24N6O3/c1-28(15-16-6-7-20-17(14-16)8-11-32-20)22-25-21(26-23(30)27-22)24-18-4-2-3-5-19(18)29-9-12-31-13-10-29/h2-8,11,14H,9-10,12-13,15H2,1H3,(H2,24,25,26,27,30) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483006
(CHEMBL1271148)Show SMILES Cc1cccc(-c2ccccc2)c1Nc1nc(O)nc(NCc2ccc3OCCCOc3c2)n1 Show InChI InChI=1S/C26H25N5O3/c1-17-7-5-10-20(19-8-3-2-4-9-19)23(17)28-25-29-24(30-26(32)31-25)27-16-18-11-12-21-22(15-18)34-14-6-13-33-21/h2-5,7-12,15H,6,13-14,16H2,1H3,(H3,27,28,29,30,31,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482999
(CHEMBL1271351)Show SMILES CN(c1nc(O)nc(NCc2ccc3occc3c2)n1)c1c(C)cccc1-c1ccccc1 Show InChI InChI=1S/C26H23N5O2/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)31(2)25-28-24(29-26(32)30-25)27-16-18-11-12-22-20(15-18)13-14-33-22/h3-15H,16H2,1-2H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482992
(CHEMBL1269927)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C25H20FN5O2/c1-31(15-16-10-11-21-18(14-16)12-13-33-21)24-28-23(29-25(32)30-24)27-22-19(8-5-9-20(22)26)17-6-3-2-4-7-17/h2-14H,15H2,1H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 reverse transcriptase Y188L mutant |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482992
(CHEMBL1269927)Show SMILES CN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C25H20FN5O2/c1-31(15-16-10-11-21-18(14-16)12-13-33-21)24-28-23(29-25(32)30-24)27-22-19(8-5-9-20(22)26)17-6-3-2-4-7-17/h2-14H,15H2,1H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 reverse transcriptase V106A mutant |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482991
(CHEMBL1270036)Show SMILES CN(Cc1ccc2OCCc2c1)c1nc(O)nc(Nc2c(C)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C26H25N5O2/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)27-24-28-25(30-26(32)29-24)31(2)16-18-11-12-22-20(15-18)13-14-33-22/h3-12,15H,13-14,16H2,1-2H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 reverse transcriptase Y188L mutant |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482994
(CHEMBL1270142)Show SMILES Cc1cccc(-c2ccccc2)c1Oc1nc(O)nc(NCc2ccc3occc3c2)n1 Show InChI InChI=1S/C25H20N4O3/c1-16-6-5-9-20(18-7-3-2-4-8-18)22(16)32-25-28-23(27-24(30)29-25)26-15-17-10-11-21-19(14-17)12-13-31-21/h2-14H,15H2,1H3,(H2,26,27,28,29,30) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483005
(CHEMBL1270245)Show SMILES Cc1cccc(-c2ccccc2)c1Nc1nc(O)nc(OCc2ccc3occc3c2)n1 Show InChI InChI=1S/C25H20N4O3/c1-16-6-5-9-20(18-7-3-2-4-8-18)22(16)26-23-27-24(30)29-25(28-23)32-15-17-10-11-21-19(14-17)12-13-31-21/h2-14H,15H2,1H3,(H2,26,27,28,29,30) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482991
(CHEMBL1270036)Show SMILES CN(Cc1ccc2OCCc2c1)c1nc(O)nc(Nc2c(C)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C26H25N5O2/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)27-24-28-25(30-26(32)29-24)31(2)16-18-11-12-22-20(15-18)13-14-33-22/h3-12,15H,13-14,16H2,1-2H3,(H2,27,28,29,30,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 reverse transcriptase V106A mutant |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483011
(CHEMBL1270940)Show SMILES Oc1nc(NCc2ccc3cc[nH]c3c2)nc(Nc2cccc(Br)c2)n1 Show InChI InChI=1S/C18H15BrN6O/c19-13-2-1-3-14(9-13)22-17-23-16(24-18(26)25-17)21-10-11-4-5-12-6-7-20-15(12)8-11/h1-9,20H,10H2,(H3,21,22,23,24,25,26) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483012
(CHEMBL1270246)Show SMILES Cc1cccc(-c2ccccc2)c1Oc1nc(N)nc(NCc2ccc3occc3c2)n1 Show InChI InChI=1S/C25H21N5O2/c1-16-6-5-9-20(18-7-3-2-4-8-18)22(16)32-25-29-23(26)28-24(30-25)27-15-17-10-11-21-19(14-17)12-13-31-21/h2-14H,15H2,1H3,(H3,26,27,28,29,30) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483010
(CHEMBL1271044)Show SMILES CC(C)(Nc1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C25H22FN5O3/c1-25(2,16-11-12-19-20(13-16)34-14-33-19)31-23-28-22(29-24(32)30-23)27-21-17(9-6-10-18(21)26)15-7-4-3-5-8-15/h3-13H,14H2,1-2H3,(H3,27,28,29,30,31,32) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50482997
(CHEMBL1271459)Show SMILES CCN(Cc1ccc2occc2c1)c1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1 Show InChI InChI=1S/C26H22FN5O2/c1-2-32(16-17-11-12-22-19(15-17)13-14-34-22)25-29-24(30-26(33)31-25)28-23-20(9-6-10-21(23)27)18-7-4-3-5-8-18/h3-15H,2,16H2,1H3,(H2,28,29,30,31,33) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483004
(CHEMBL1270345)Show SMILES Fc1cccc(-c2ccccc2)c1Nc1nc(Cl)nc(NCc2ccc3occc3c2)n1 Show InChI InChI=1S/C24H17ClFN5O/c25-22-29-23(27-14-15-9-10-20-17(13-15)11-12-32-20)31-24(30-22)28-21-18(7-4-8-19(21)26)16-5-2-1-3-6-16/h1-13H,14H2,(H2,27,28,29,30,31) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483000
(CHEMBL1271147)Show SMILES Cc1cccc(-c2ccccc2)c1Nc1nc(O)nc(NCc2ccc3n(ccc3c2)S(C)(=O)=O)n1 Show InChI InChI=1S/C26H24N6O3S/c1-17-7-6-10-21(19-8-4-3-5-9-19)23(17)28-25-29-24(30-26(33)31-25)27-16-18-11-12-22-20(15-18)13-14-32(22)36(2,34)35/h3-15H,16H2,1-2H3,(H3,27,28,29,30,31,33) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50483002
(CHEMBL1270941)Show SMILES Oc1nc(NCc2ccc3cc[nH]c3c2)nc(Nc2cccc(Oc3ccccc3)c2)n1 Show InChI InChI=1S/C24H20N6O2/c31-24-29-22(26-15-16-9-10-17-11-12-25-21(17)13-16)28-23(30-24)27-18-5-4-8-20(14-18)32-19-6-2-1-3-7-19/h1-14,25H,15H2,(H3,26,27,28,29,30,31) | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ansaris
Curated by ChEMBL
| Assay Description
Inhibition of wild type HIV1 reverse transcriptase |
Bioorg Med Chem Lett 20: 6592-6 (2010)
Article DOI: 10.1016/j.bmcl.2010.09.034
BindingDB Entry DOI: 10.7270/Q2NG4TG2 |
More data for this
Ligand-Target Pair | |
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