Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with all data for entry = 50004653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM60579 ((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...) Show SMILES Oc1ccc(\C=C2/SC(=O)NC2=O)cc1 Show InChI InChI=1S/C10H7NO3S/c12-7-3-1-6(2-4-7)5-8-9(13)11-10(14)15-8/h1-5,12H,(H,11,13,14)/b8-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	374	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485276 (CHEMBL233375) Show SMILES COc1ccc(\C=C2/SC(=O)NC2=O)cc1O Show InChI InChI=1S/C11H9NO4S/c1-16-8-3-2-6(4-7(8)13)5-9-10(14)12-11(15)17-9/h2-5,13H,1H3,(H,12,14,15)/b9-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	413	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM60579 ((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...) Show SMILES Oc1ccc(\C=C2/SC(=O)NC2=O)cc1 Show InChI InChI=1S/C10H7NO3S/c12-7-3-1-6(2-4-7)5-8-9(13)11-10(14)15-8/h1-5,12H,(H,11,13,14)/b8-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 20 uM by Line-Weaver-Burk plot analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485276 (CHEMBL233375) Show SMILES COc1ccc(\C=C2/SC(=O)NC2=O)cc1O Show InChI InChI=1S/C11H9NO4S/c1-16-8-3-2-6(4-7(8)13)5-9-10(14)12-11(15)17-9/h2-5,13H,1H3,(H,12,14,15)/b9-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 20 uM by Line-Weaver-Burk plot analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50485276 (CHEMBL233375) Show SMILES COc1ccc(\C=C2/SC(=O)NC2=O)cc1O Show InChI InChI=1S/C11H9NO4S/c1-16-8-3-2-6(4-7(8)13)5-9-10(14)12-11(15)17-9/h2-5,13H,1H3,(H,12,14,15)/b9-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM60579 ((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...) Show SMILES Oc1ccc(\C=C2/SC(=O)NC2=O)cc1 Show InChI InChI=1S/C10H7NO3S/c12-7-3-1-6(2-4-7)5-8-9(13)11-10(14)15-8/h1-5,12H,(H,11,13,14)/b8-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair