Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with all data for entry = 50006126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50241361 (CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	4.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hungkuang University Curated by ChEMBL					Assay Description Mixed-type inhibition of mushroom tyrosinase-mediated L-tyrosine oxidation assessed as enzyme-inhibitor complex after 10 mins by Lineweaver-Burk plot...				Bioorg Med Chem 22: 2809-15 (2014) Article DOI: 10.1016/j.bmc.2014.03.009 BindingDB Entry DOI: 10.7270/Q2417125
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50497083 (CHEMBL3260774) Show SMILES Sc1ncc[nH]1 Show InChI InChI=1S/C3H4N2S/c6-3-4-1-2-5-3/h1-2H,(H2,4,5,6)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	5.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hungkuang University Curated by ChEMBL					Assay Description Mixed-type inhibition of mushroom tyrosinase-mediated L-tyrosine oxidation assessed as enzyme-inhibitor complex after 10 mins by Lineweaver-Burk plot...				Bioorg Med Chem 22: 2809-15 (2014) Article DOI: 10.1016/j.bmc.2014.03.009 BindingDB Entry DOI: 10.7270/Q2417125
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50497084 (CHEMBL3260775) Show SMILES Cn1ccn(C(=O)OC(C)(C)C)c1=S Show InChI InChI=1S/C9H14N2O2S/c1-9(2,3)13-8(12)11-6-5-10(4)7(11)14/h5-6H,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.75E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hungkuang University Curated by ChEMBL					Assay Description Noncompetitive inhibition of mushroom tyrosinase-mediated L-tyrosine oxidation assessed as enzyme-inhibitor complex after 10 mins by Lineweaver-Burk ...				Bioorg Med Chem 22: 2809-15 (2014) Article DOI: 10.1016/j.bmc.2014.03.009 BindingDB Entry DOI: 10.7270/Q2417125
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50241361 (CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.43E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hungkuang University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase-mediated L-tyrosine hydroxylation after 30 mins by ELISA				Bioorg Med Chem 22: 2809-15 (2014) Article DOI: 10.1016/j.bmc.2014.03.009 BindingDB Entry DOI: 10.7270/Q2417125
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50497084 (CHEMBL3260775) Show SMILES Cn1ccn(C(=O)OC(C)(C)C)c1=S Show InChI InChI=1S/C9H14N2O2S/c1-9(2,3)13-8(12)11-6-5-10(4)7(11)14/h5-6H,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hungkuang University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase-mediated L-tyrosine hydroxylation after 30 mins by ELISA				Bioorg Med Chem 22: 2809-15 (2014) Article DOI: 10.1016/j.bmc.2014.03.009 BindingDB Entry DOI: 10.7270/Q2417125
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50497083 (CHEMBL3260774) Show SMILES Sc1ncc[nH]1 Show InChI InChI=1S/C3H4N2S/c6-3-4-1-2-5-3/h1-2H,(H2,4,5,6)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.11E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hungkuang University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase-mediated L-tyrosine hydroxylation after 30 mins by ELISA				Bioorg Med Chem 22: 2809-15 (2014) Article DOI: 10.1016/j.bmc.2014.03.009 BindingDB Entry DOI: 10.7270/Q2417125
					More data for this Ligand-Target Pair