Found 68 hits Enz. Inhib. hit(s) with all data for entry = 50006499 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500363
![PNG](/data/jpeg/tenK5050/BindingDB_50500363.png) (CHEMBL3747481)Show SMILES FC(F)(F)c1cccc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)c1 Show InChI InChI=1S/C22H16F3N5O2/c23-22(24,25)14-2-1-3-15(9-14)29-21(31)30-7-6-13-8-16(4-5-19(13)30)32-20-17-10-26-11-18(17)27-12-28-20/h1-9,12,26H,10-11H2,(H,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500371
![PNG](/data/jpeg/tenK5050/BindingDB_50500371.png) (CHEMBL3746941)Show SMILES CC1(CC1)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)n[nH]1 Show InChI InChI=1S/C22H21N7O2/c1-22(5-6-22)18-9-19(28-27-18)26-21(30)29-7-4-13-8-14(2-3-17(13)29)31-20-15-10-23-11-16(15)24-12-25-20/h2-4,7-9,12,23H,5-6,10-11H2,1H3,(H2,26,27,28,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500370
![PNG](/data/jpeg/tenK5050/BindingDB_50500370.png) (CHEMBL3746273)Show SMILES C[C@@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc([nH]n1)C1(C)CC1 |r| Show InChI InChI=1S/C24H25N7O2/c1-14-9-17-18(12-25-14)26-13-27-22(17)33-16-3-4-19-15(10-16)5-8-31(19)23(32)28-21-11-20(29-30-21)24(2)6-7-24/h3-5,8,10-11,13-14,25H,6-7,9,12H2,1-2H3,(H2,28,29,30,32)/t14-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270424
![PNG](/data/jpeg/tenK5027/BindingDB_50270424.png) (CHEMBL3746776)Show SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc([nH]n1)C1(C)CC1 |r| Show InChI InChI=1S/C24H25N7O2/c1-14-9-17-18(12-25-14)26-13-27-22(17)33-16-3-4-19-15(10-16)5-8-31(19)23(32)28-21-11-20(29-30-21)24(2)6-7-24/h3-5,8,10-11,13-14,25H,6-7,9,12H2,1-2H3,(H2,28,29,30,32)/t14-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500377
![PNG](/data/jpeg/tenK5050/BindingDB_50500377.png) (CHEMBL3747084)Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)n[nH]1 Show InChI InChI=1S/C23H25N7O2/c1-23(2,3)19-11-20(29-28-19)27-22(31)30-9-7-14-10-15(4-5-18(14)30)32-21-16-6-8-24-12-17(16)25-13-26-21/h4-5,7,9-11,13,24H,6,8,12H2,1-3H3,(H2,27,28,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270438
![PNG](/data/jpeg/tenK5027/BindingDB_50270438.png) (CHEMBL3747273)Show SMILES CC(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1 Show InChI InChI=1S/C21H20N6O3/c1-12(2)18-8-19(26-30-18)25-21(28)27-6-5-13-7-14(3-4-17(13)27)29-20-15-9-22-10-16(15)23-11-24-20/h3-8,11-12,22H,9-10H2,1-2H3,(H,25,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500372
![PNG](/data/jpeg/tenK5050/BindingDB_50500372.png) (CHEMBL3745943)Show SMILES CC(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)n[nH]1 Show InChI InChI=1S/C22H23N7O2/c1-13(2)17-10-20(28-27-17)26-22(30)29-8-6-14-9-15(3-4-19(14)29)31-21-16-5-7-23-11-18(16)24-12-25-21/h3-4,6,8-10,12-13,23H,5,7,11H2,1-2H3,(H2,26,27,28,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500371
![PNG](/data/jpeg/tenK5050/BindingDB_50500371.png) (CHEMBL3746941)Show SMILES CC1(CC1)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)n[nH]1 Show InChI InChI=1S/C22H21N7O2/c1-22(5-6-22)18-9-19(28-27-18)26-21(30)29-7-4-13-8-14(2-3-17(13)29)31-20-15-10-23-11-16(15)24-12-25-20/h2-4,7-9,12,23H,5-6,10-11H2,1H3,(H2,26,27,28,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270423
![PNG](/data/jpeg/tenK5027/BindingDB_50270423.png) (CHEMBL3746562)Show SMILES CC1(CC1)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)n[nH]1 Show InChI InChI=1S/C23H23N7O2/c1-23(6-7-23)19-11-20(29-28-19)27-22(31)30-9-5-14-10-15(2-3-18(14)30)32-21-16-4-8-24-12-17(16)25-13-26-21/h2-3,5,9-11,13,24H,4,6-8,12H2,1H3,(H2,27,28,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500368
![PNG](/data/jpeg/tenK5050/BindingDB_50500368.png) (CHEMBL3746595)Show SMILES OCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C21H15F3N4O3/c22-21(23,24)14-2-1-3-15(9-14)27-20(30)28-7-6-13-8-17(4-5-18(13)28)31-19-10-16(11-29)25-12-26-19/h1-10,12,29H,11H2,(H,27,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500369
![PNG](/data/jpeg/tenK5050/BindingDB_50500369.png) (CHEMBL3747669)Show SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc(on1)C(C)(C)C |r| Show InChI InChI=1S/C24H26N6O3/c1-14-9-17-18(12-25-14)26-13-27-22(17)32-16-5-6-19-15(10-16)7-8-30(19)23(31)28-21-11-20(33-29-21)24(2,3)4/h5-8,10-11,13-14,25H,9,12H2,1-4H3,(H,28,29,31)/t14-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270423
![PNG](/data/jpeg/tenK5027/BindingDB_50270423.png) (CHEMBL3746562)Show SMILES CC1(CC1)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)n[nH]1 Show InChI InChI=1S/C23H23N7O2/c1-23(6-7-23)19-11-20(29-28-19)27-22(31)30-9-5-14-10-15(2-3-18(14)30)32-21-16-4-8-24-12-17(16)25-13-26-21/h2-3,5,9-11,13,24H,4,6-8,12H2,1H3,(H2,27,28,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500361
![PNG](/data/jpeg/tenK5050/BindingDB_50500361.png) (CHEMBL3746204)Show SMILES CNCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2ccc(F)c(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C22H17F4N5O2/c1-27-11-15-10-20(29-12-28-15)33-16-3-5-19-13(8-16)6-7-31(19)21(32)30-14-2-4-18(23)17(9-14)22(24,25)26/h2-10,12,27H,11H2,1H3,(H,30,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500372
![PNG](/data/jpeg/tenK5050/BindingDB_50500372.png) (CHEMBL3745943)Show SMILES CC(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)n[nH]1 Show InChI InChI=1S/C22H23N7O2/c1-13(2)17-10-20(28-27-17)26-22(30)29-8-6-14-9-15(3-4-19(14)29)31-21-16-5-7-23-11-18(16)24-12-25-21/h3-4,6,8-10,12-13,23H,5,7,11H2,1-2H3,(H2,26,27,28,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270419
![PNG](/data/jpeg/tenK5027/BindingDB_50270419.png) (CHEMBL3746370)Show SMILES CC1(CC1)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1 Show InChI InChI=1S/C22H20N6O3/c1-22(5-6-22)18-9-19(27-31-18)26-21(29)28-7-4-13-8-14(2-3-17(13)28)30-20-15-10-23-11-16(15)24-12-25-20/h2-4,7-9,12,23H,5-6,10-11H2,1H3,(H,26,27,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500381
![PNG](/data/jpeg/tenK5050/BindingDB_50500381.png) (CHEMBL3746052)Show SMILES CC(=O)N1CCc2c(C1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H20F3N5O3/c1-15(34)32-9-8-20-21(13-32)29-14-30-23(20)36-19-5-6-22-16(11-19)7-10-33(22)24(35)31-18-4-2-3-17(12-18)25(26,27)28/h2-7,10-12,14H,8-9,13H2,1H3,(H,31,35) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270411
![PNG](/data/jpeg/tenK5027/BindingDB_50270411.png) (CHEMBL3747063)Show SMILES CNCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C22H18F3N5O2/c1-26-12-17-11-20(28-13-27-17)32-18-5-6-19-14(9-18)7-8-30(19)21(31)29-16-4-2-3-15(10-16)22(23,24)25/h2-11,13,26H,12H2,1H3,(H,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500377
![PNG](/data/jpeg/tenK5050/BindingDB_50500377.png) (CHEMBL3747084)Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)n[nH]1 Show InChI InChI=1S/C23H25N7O2/c1-23(2,3)19-11-20(29-28-19)27-22(31)30-9-7-14-10-15(4-5-18(14)30)32-21-16-6-8-24-12-17(16)25-13-26-21/h4-5,7,9-11,13,24H,6,8,12H2,1-3H3,(H2,27,28,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270424
![PNG](/data/jpeg/tenK5027/BindingDB_50270424.png) (CHEMBL3746776)Show SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc([nH]n1)C1(C)CC1 |r| Show InChI InChI=1S/C24H25N7O2/c1-14-9-17-18(12-25-14)26-13-27-22(17)33-16-3-4-19-15(10-16)5-8-31(19)23(32)28-21-11-20(29-30-21)24(2)6-7-24/h3-5,8,10-11,13-14,25H,6-7,9,12H2,1-2H3,(H2,28,29,30,32)/t14-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500370
![PNG](/data/jpeg/tenK5050/BindingDB_50500370.png) (CHEMBL3746273)Show SMILES C[C@@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc([nH]n1)C1(C)CC1 |r| Show InChI InChI=1S/C24H25N7O2/c1-14-9-17-18(12-25-14)26-13-27-22(17)33-16-3-4-19-15(10-16)5-8-31(19)23(32)28-21-11-20(29-30-21)24(2)6-7-24/h3-5,8,10-11,13-14,25H,6-7,9,12H2,1-2H3,(H2,28,29,30,32)/t14-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500374
![PNG](/data/jpeg/tenK5050/BindingDB_50500374.png) (CHEMBL3746141)Show SMILES C[C@@H]1NCc2ncnc(Oc3ccc4n(ccc4c3)C(=O)Nc3cc(on3)C(C)(C)C)c12 |r| Show InChI InChI=1S/C23H24N6O3/c1-13-20-16(11-24-13)25-12-26-21(20)31-15-5-6-17-14(9-15)7-8-29(17)22(30)27-19-10-18(32-28-19)23(2,3)4/h5-10,12-13,24H,11H2,1-4H3,(H,27,28,30)/t13-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270438
![PNG](/data/jpeg/tenK5027/BindingDB_50270438.png) (CHEMBL3747273)Show SMILES CC(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1 Show InChI InChI=1S/C21H20N6O3/c1-12(2)18-8-19(26-30-18)25-21(28)27-6-5-13-7-14(3-4-17(13)27)29-20-15-9-22-10-16(15)23-11-24-20/h3-8,11-12,22H,9-10H2,1-2H3,(H,25,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173601
![PNG](/data/jpeg/tenK5017/BindingDB_50173601.png) (CHEMBL3745816)Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1 Show InChI InChI=1S/C22H22N6O3/c1-22(2,3)18-9-19(27-31-18)26-21(29)28-7-6-13-8-14(4-5-17(13)28)30-20-15-10-23-11-16(15)24-12-25-20/h4-9,12,23H,10-11H2,1-3H3,(H,26,27,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500367
![PNG](/data/jpeg/tenK5050/BindingDB_50500367.png) (CHEMBL3747226)Show SMILES FC(F)(F)c1cccc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)c1 Show InChI InChI=1S/C23H18F3N5O2/c24-23(25,26)15-2-1-3-16(11-15)30-22(32)31-9-7-14-10-17(4-5-20(14)31)33-21-18-6-8-27-12-19(18)28-13-29-21/h1-5,7,9-11,13,27H,6,8,12H2,(H,30,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500378
![PNG](/data/jpeg/tenK5050/BindingDB_50500378.png) (CHEMBL3745924)Show SMILES CCN1CCc2c(C1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H22F3N5O2/c1-2-32-10-9-20-21(14-32)29-15-30-23(20)35-19-6-7-22-16(12-19)8-11-33(22)24(34)31-18-5-3-4-17(13-18)25(26,27)28/h3-8,11-13,15H,2,9-10,14H2,1H3,(H,31,34) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500378
![PNG](/data/jpeg/tenK5050/BindingDB_50500378.png) (CHEMBL3745924)Show SMILES CCN1CCc2c(C1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H22F3N5O2/c1-2-32-10-9-20-21(14-32)29-15-30-23(20)35-19-6-7-22-16(12-19)8-11-33(22)24(34)31-18-5-3-4-17(13-18)25(26,27)28/h3-8,11-13,15H,2,9-10,14H2,1H3,(H,31,34) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270411
![PNG](/data/jpeg/tenK5027/BindingDB_50270411.png) (CHEMBL3747063)Show SMILES CNCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C22H18F3N5O2/c1-26-12-17-11-20(28-13-27-17)32-18-5-6-19-14(9-18)7-8-30(19)21(31)29-16-4-2-3-15(10-16)22(23,24)25/h2-11,13,26H,12H2,1H3,(H,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500368
![PNG](/data/jpeg/tenK5050/BindingDB_50500368.png) (CHEMBL3746595)Show SMILES OCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C21H15F3N4O3/c22-21(23,24)14-2-1-3-15(9-14)27-20(30)28-7-6-13-8-17(4-5-18(13)28)31-19-10-16(11-29)25-12-26-19/h1-10,12,29H,11H2,(H,27,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270419
![PNG](/data/jpeg/tenK5027/BindingDB_50270419.png) (CHEMBL3746370)Show SMILES CC1(CC1)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1 Show InChI InChI=1S/C22H20N6O3/c1-22(5-6-22)18-9-19(27-31-18)26-21(29)28-7-4-13-8-14(2-3-17(13)28)30-20-15-10-23-11-16(15)24-12-25-20/h2-4,7-9,12,23H,5-6,10-11H2,1H3,(H,26,27,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500380
![PNG](/data/jpeg/tenK5050/BindingDB_50500380.png) (CHEMBL3747182)Show SMILES C[C@@H]1NCc2ncnc(Oc3ccc4n(ccc4c3)C(=O)Nc3cccc(c3)C(F)(F)F)c12 |r| Show InChI InChI=1S/C23H18F3N5O2/c1-13-20-18(11-27-13)28-12-29-21(20)33-17-5-6-19-14(9-17)7-8-31(19)22(32)30-16-4-2-3-15(10-16)23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,30,32)/t13-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500379
![PNG](/data/jpeg/tenK5050/BindingDB_50500379.png) (CHEMBL3746359)Show SMILES Nc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C20H14F3N5O2/c21-20(22,23)13-2-1-3-14(9-13)27-19(29)28-7-6-12-8-15(4-5-16(12)28)30-18-10-17(24)25-11-26-18/h1-11H,(H,27,29)(H2,24,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500373
![PNG](/data/jpeg/tenK5050/BindingDB_50500373.png) (CHEMBL3746735)Show SMILES C[C@H]1NCc2ncnc(Oc3ccc4n(ccc4c3)C(=O)Nc3cccc(c3)C(F)(F)F)c12 |r| Show InChI InChI=1S/C23H18F3N5O2/c1-13-20-18(11-27-13)28-12-29-21(20)33-17-5-6-19-14(9-17)7-8-31(19)22(32)30-16-4-2-3-15(10-16)23(24,25)26/h2-10,12-13,27H,11H2,1H3,(H,30,32)/t13-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500366
![PNG](/data/jpeg/tenK5050/BindingDB_50500366.png) (CHEMBL3746357)Show SMILES FC(F)(F)c1cccc(NC(=O)n2ccc3cc(Oc4ncnc5CCNCc45)ccc23)c1 Show InChI InChI=1S/C23H18F3N5O2/c24-23(25,26)15-2-1-3-16(11-15)30-22(32)31-9-7-14-10-17(4-5-20(14)31)33-21-18-12-27-8-6-19(18)28-13-29-21/h1-5,7,9-11,13,27H,6,8,12H2,(H,30,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500374
![PNG](/data/jpeg/tenK5050/BindingDB_50500374.png) (CHEMBL3746141)Show SMILES C[C@@H]1NCc2ncnc(Oc3ccc4n(ccc4c3)C(=O)Nc3cc(on3)C(C)(C)C)c12 |r| Show InChI InChI=1S/C23H24N6O3/c1-13-20-16(11-24-13)25-12-26-21(20)31-15-5-6-17-14(9-15)7-8-29(17)22(30)27-19-10-18(32-28-19)23(2,3)4/h5-10,12-13,24H,11H2,1-4H3,(H,27,28,30)/t13-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500367
![PNG](/data/jpeg/tenK5050/BindingDB_50500367.png) (CHEMBL3747226)Show SMILES FC(F)(F)c1cccc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)c1 Show InChI InChI=1S/C23H18F3N5O2/c24-23(25,26)15-2-1-3-16(11-15)30-22(32)31-9-7-14-10-17(4-5-20(14)31)33-21-18-6-8-27-12-19(18)28-13-29-21/h1-5,7,9-11,13,27H,6,8,12H2,(H,30,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500365
![PNG](/data/jpeg/tenK5050/BindingDB_50500365.png) (CHEMBL3746897)Show SMILES C[C@@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C24H20F3N5O2/c1-14-9-19-20(12-28-14)29-13-30-22(19)34-18-5-6-21-15(10-18)7-8-32(21)23(33)31-17-4-2-3-16(11-17)24(25,26)27/h2-8,10-11,13-14,28H,9,12H2,1H3,(H,31,33)/t14-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500362
![PNG](/data/jpeg/tenK5050/BindingDB_50500362.png) (CHEMBL3747266)Show SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C24H20F3N5O2/c1-14-9-19-20(12-28-14)29-13-30-22(19)34-18-5-6-21-15(10-18)7-8-32(21)23(33)31-17-4-2-3-16(11-17)24(25,26)27/h2-8,10-11,13-14,28H,9,12H2,1H3,(H,31,33)/t14-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270422
![PNG](/data/jpeg/tenK5027/BindingDB_50270422.png) (CHEMBL3746122)Show SMILES O=C(Nc1cc(on1)C1CC1)n1ccc2cc(Oc3ncnc4CNCc34)ccc12 Show InChI InChI=1S/C21H18N6O3/c28-21(25-19-8-18(30-26-19)12-1-2-12)27-6-5-13-7-14(3-4-17(13)27)29-20-15-9-22-10-16(15)23-11-24-20/h3-8,11-12,22H,1-2,9-10H2,(H,25,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500363
![PNG](/data/jpeg/tenK5050/BindingDB_50500363.png) (CHEMBL3747481)Show SMILES FC(F)(F)c1cccc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)c1 Show InChI InChI=1S/C22H16F3N5O2/c23-22(24,25)14-2-1-3-15(9-14)29-21(31)30-7-6-13-8-16(4-5-19(13)30)32-20-17-10-26-11-18(17)27-12-28-20/h1-9,12,26H,10-11H2,(H,29,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500369
![PNG](/data/jpeg/tenK5050/BindingDB_50500369.png) (CHEMBL3747669)Show SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc(on1)C(C)(C)C |r| Show InChI InChI=1S/C24H26N6O3/c1-14-9-17-18(12-25-14)26-13-27-22(17)32-16-5-6-19-15(10-16)7-8-30(19)23(31)28-21-11-20(33-29-21)24(2,3)4/h5-8,10-11,13-14,25H,9,12H2,1-4H3,(H,28,29,31)/t14-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500364
![PNG](/data/jpeg/tenK5050/BindingDB_50500364.png) (CHEMBL3746226)Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)no1 Show InChI InChI=1S/C23H24N6O3/c1-23(2,3)19-11-20(28-32-19)27-22(30)29-9-7-14-10-15(4-5-18(14)29)31-21-16-6-8-24-12-17(16)25-13-26-21/h4-5,7,9-11,13,24H,6,8,12H2,1-3H3,(H,27,28,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500364
![PNG](/data/jpeg/tenK5050/BindingDB_50500364.png) (CHEMBL3746226)Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)no1 Show InChI InChI=1S/C23H24N6O3/c1-23(2,3)19-11-20(28-32-19)27-22(30)29-9-7-14-10-15(4-5-18(14)29)31-21-16-6-8-24-12-17(16)25-13-26-21/h4-5,7,9-11,13,24H,6,8,12H2,1-3H3,(H,27,28,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50270422
![PNG](/data/jpeg/tenK5027/BindingDB_50270422.png) (CHEMBL3746122)Show SMILES O=C(Nc1cc(on1)C1CC1)n1ccc2cc(Oc3ncnc4CNCc34)ccc12 Show InChI InChI=1S/C21H18N6O3/c28-21(25-19-8-18(30-26-19)12-1-2-12)27-6-5-13-7-14(3-4-17(13)27)29-20-15-9-22-10-16(15)23-11-24-20/h3-8,11-12,22H,1-2,9-10H2,(H,25,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173601
![PNG](/data/jpeg/tenK5017/BindingDB_50173601.png) (CHEMBL3745816)Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1 Show InChI InChI=1S/C22H22N6O3/c1-22(2,3)18-9-19(27-31-18)26-21(29)28-7-6-13-8-14(4-5-17(13)28)30-20-15-10-23-11-16(15)24-12-25-20/h4-9,12,23H,10-11H2,1-3H3,(H,26,27,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500362
![PNG](/data/jpeg/tenK5050/BindingDB_50500362.png) (CHEMBL3747266)Show SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C24H20F3N5O2/c1-14-9-19-20(12-28-14)29-13-30-22(19)34-18-5-6-21-15(10-18)7-8-32(21)23(33)31-17-4-2-3-16(11-17)24(25,26)27/h2-8,10-11,13-14,28H,9,12H2,1H3,(H,31,33)/t14-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500361
![PNG](/data/jpeg/tenK5050/BindingDB_50500361.png) (CHEMBL3746204)Show SMILES CNCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2ccc(F)c(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C22H17F4N5O2/c1-27-11-15-10-20(29-12-28-15)33-16-3-5-19-13(8-16)6-7-31(19)21(32)30-14-2-4-18(23)17(9-14)22(24,25)26/h2-10,12,27H,11H2,1H3,(H,30,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50270424
![PNG](/data/jpeg/tenK5027/BindingDB_50270424.png) (CHEMBL3746776)Show SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc([nH]n1)C1(C)CC1 |r| Show InChI InChI=1S/C24H25N7O2/c1-14-9-17-18(12-25-14)26-13-27-22(17)33-16-3-4-19-15(10-16)5-8-31(19)23(32)28-21-11-20(29-30-21)24(2)6-7-24/h3-5,8,10-11,13-14,25H,6-7,9,12H2,1-2H3,(H2,28,29,30,32)/t14-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Ret (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500366
![PNG](/data/jpeg/tenK5050/BindingDB_50500366.png) (CHEMBL3746357)Show SMILES FC(F)(F)c1cccc(NC(=O)n2ccc3cc(Oc4ncnc5CCNCc45)ccc23)c1 Show InChI InChI=1S/C23H18F3N5O2/c24-23(25,26)15-2-1-3-16(11-15)30-22(32)31-9-7-14-10-17(4-5-20(14)31)33-21-18-12-27-8-6-19(18)28-13-29-21/h1-5,7,9-11,13,27H,6,8,12H2,(H,30,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500365
![PNG](/data/jpeg/tenK5050/BindingDB_50500365.png) (CHEMBL3746897)Show SMILES C[C@@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C24H20F3N5O2/c1-14-9-19-20(12-28-14)29-13-30-22(19)34-18-5-6-21-15(10-18)7-8-32(21)23(33)31-17-4-2-3-16(11-17)24(25,26)27/h2-8,10-11,13-14,28H,9,12H2,1H3,(H,31,33)/t14-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a... |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50500375
![PNG](/data/jpeg/tenK5050/BindingDB_50500375.png) (CHEMBL3747565)Show SMILES CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)on1 Show InChI InChI=1S/C22H22N6O3/c1-22(2,3)18-9-19(31-27-18)26-21(29)28-7-6-13-8-14(4-5-17(13)28)30-20-15-10-23-11-16(15)24-12-25-20/h4-9,12,23H,10-11H2,1-3H3,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
J Med Chem 58: 9273-86 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9 |
More data for this Ligand-Target Pair | |