Compile Data Set for Download or QSAR

Found 116 hits Enz. Inhib. hit(s) with all data for entry = 50006847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI InChI=1S/C17H15N3O/c1-10-13(2-3-15-14(10)5-7-19-17(15)21)12-8-11-4-6-18-16(11)20-9-12/h2-4,6,8-9H,5,7H2,1H3,(H,18,20)(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI InChI=1S/C17H15N3O/c1-10-13(2-3-15-14(10)5-7-19-17(15)21)12-8-11-4-6-18-16(11)20-9-12/h2-4,6,8-9H,5,7H2,1H3,(H,18,20)(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C18H16N2O/c1-11-14(3-4-16-15(11)7-9-20-18(16)21)12-2-5-17-13(10-12)6-8-19-17/h2-6,8,10,19H,7,9H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503863 (CHEMBL4450751) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C15H12ClNO/c16-13-3-1-2-10(9-13)11-4-5-14-12(8-11)6-7-17-15(14)18/h1-5,8-9H,6-7H2,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C18H16N2O/c1-11-14(3-4-16-15(11)7-9-20-18(16)21)12-2-5-17-13(10-12)6-8-19-17/h2-6,8,10,19H,7,9H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503863 (CHEMBL4450751) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C15H12ClNO/c16-13-3-1-2-10(9-13)11-4-5-14-12(8-11)6-7-17-15(14)18/h1-5,8-9H,6-7H2,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503870 (CHEMBL4580007) Show SMILES O=C1NCCc2c1cccc2-c1ccccc1 Show InChI InChI=1S/C15H13NO/c17-15-14-8-4-7-12(13(14)9-10-16-15)11-5-2-1-3-6-11/h1-8H,9-10H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503870 (CHEMBL4580007) Show SMILES O=C1NCCc2c1cccc2-c1ccccc1 Show InChI InChI=1S/C15H13NO/c17-15-14-8-4-7-12(13(14)9-10-16-15)11-5-2-1-3-6-11/h1-8H,9-10H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503869 (CHEMBL4572268) Show SMILES Fc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C15H12FNO/c16-13-3-1-2-10(9-13)11-4-5-14-12(8-11)6-7-17-15(14)18/h1-5,8-9H,6-7H2,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503856 (CHEMBL4559852) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccncc1 Show InChI InChI=1S/C15H14N2O/c1-10-12(11-4-7-16-8-5-11)2-3-14-13(10)6-9-17-15(14)18/h2-5,7-8H,6,9H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503869 (CHEMBL4572268) Show SMILES Fc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C15H12FNO/c16-13-3-1-2-10(9-13)11-4-5-14-12(8-11)6-7-17-15(14)18/h1-5,8-9H,6-7H2,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503856 (CHEMBL4559852) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccncc1 Show InChI InChI=1S/C15H14N2O/c1-10-12(11-4-7-16-8-5-11)2-3-14-13(10)6-9-17-15(14)18/h2-5,7-8H,6,9H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C17H15NO2/c1-11(19)12-3-2-4-13(9-12)14-5-6-16-15(10-14)7-8-18-17(16)20/h2-6,9-10H,7-8H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503865 (CHEMBL4544104) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccccc1 Show InChI InChI=1S/C16H15NO/c1-11-13(12-5-3-2-4-6-12)7-8-15-14(11)9-10-17-16(15)18/h2-8H,9-10H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C17H15NO2/c1-11(19)12-3-2-4-13(9-12)14-5-6-16-15(10-14)7-8-18-17(16)20/h2-6,9-10H,7-8H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503865 (CHEMBL4544104) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccccc1 Show InChI InChI=1S/C16H15NO/c1-11-13(12-5-3-2-4-6-12)7-8-15-14(11)9-10-17-16(15)18/h2-8H,9-10H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503859 (CHEMBL4524394) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(Cl)c1 Show InChI InChI=1S/C15H13ClN2O/c1-9-11(10-4-6-17-14(16)8-10)2-3-13-12(9)5-7-18-15(13)19/h2-4,6,8H,5,7H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503851 (CHEMBL4585230) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2ccccc2c1 Show InChI InChI=1S/C19H16N2O/c1-12-15(6-7-17-16(12)8-9-20-19(17)22)14-10-13-4-2-3-5-18(13)21-11-14/h2-7,10-11H,8-9H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503851 (CHEMBL4585230) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2ccccc2c1 Show InChI InChI=1S/C19H16N2O/c1-12-15(6-7-17-16(12)8-9-20-19(17)22)14-10-13-4-2-3-5-18(13)21-11-14/h2-7,10-11H,8-9H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O/c1-9-11(2-3-13-12(9)5-7-21-15(13)22)10-4-6-20-14(8-10)16(17,18)19/h2-4,6,8H,5,7H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503859 (CHEMBL4524394) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(Cl)c1 Show InChI InChI=1S/C15H13ClN2O/c1-9-11(10-4-6-17-14(16)8-10)2-3-13-12(9)5-7-18-15(13)19/h2-4,6,8H,5,7H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O/c1-9-11(2-3-13-12(9)5-7-21-15(13)22)10-4-6-20-14(8-10)16(17,18)19/h2-4,6,8H,5,7H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503866 (CHEMBL4589699) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(F)c1 Show InChI InChI=1S/C15H13FN2O/c1-9-11(10-4-6-17-14(16)8-10)2-3-13-12(9)5-7-18-15(13)19/h2-4,6,8H,5,7H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503866 (CHEMBL4589699) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(F)c1 Show InChI InChI=1S/C15H13FN2O/c1-9-11(10-4-6-17-14(16)8-10)2-3-13-12(9)5-7-18-15(13)19/h2-4,6,8H,5,7H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Cc1cccc2C(=O)NCCc12 Show InChI InChI=1S/C10H11NO/c1-7-3-2-4-9-8(7)5-6-11-10(9)12/h2-4H,5-6H2,1H3,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one | CHE...) Show SMILES Cc1cccc2C(=O)NCCc12 Show InChI InChI=1S/C10H11NO/c1-7-3-2-4-9-8(7)5-6-11-10(9)12/h2-4H,5-6H2,1H3,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503860 (CHEMBL4475063) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(F)c1 Show InChI InChI=1S/C15H13FN2O/c1-9-12(10-6-11(16)8-17-7-10)2-3-14-13(9)4-5-18-15(14)19/h2-3,6-8H,4-5H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503860 (CHEMBL4475063) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(F)c1 Show InChI InChI=1S/C15H13FN2O/c1-9-12(10-6-11(16)8-17-7-10)2-3-14-13(9)4-5-18-15(14)19/h2-3,6-8H,4-5H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503868 (CHEMBL4452747) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H12F3NO/c17-16(18,19)13-3-1-2-10(9-13)11-4-5-14-12(8-11)6-7-20-15(14)21/h1-5,8-9H,6-7H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503868 (CHEMBL4452747) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H12F3NO/c17-16(18,19)13-3-1-2-10(9-13)11-4-5-14-12(8-11)6-7-20-15(14)21/h1-5,8-9H,6-7H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503862 (CHEMBL4565850) Show SMILES O=C1NCCc2cc(ccc12)-c1ccccc1 Show InChI InChI=1S/C15H13NO/c17-15-14-7-6-12(10-13(14)8-9-16-15)11-4-2-1-3-5-11/h1-7,10H,8-9H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503862 (CHEMBL4565850) Show SMILES O=C1NCCc2cc(ccc12)-c1ccccc1 Show InChI InChI=1S/C15H13NO/c17-15-14-7-6-12(10-13(14)8-9-16-15)11-4-2-1-3-5-11/h1-7,10H,8-9H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503855 (CHEMBL4513504) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cccnc1 Show InChI InChI=1S/C15H14N2O/c1-10-12(11-3-2-7-16-9-11)4-5-14-13(10)6-8-17-15(14)18/h2-5,7,9H,6,8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503855 (CHEMBL4513504) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cccnc1 Show InChI InChI=1S/C15H14N2O/c1-10-12(11-3-2-7-16-9-11)4-5-14-13(10)6-8-17-15(14)18/h2-5,7,9H,6,8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503867 (CHEMBL4447011) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O/c1-9-12(2-3-14-13(9)4-5-21-15(14)22)10-6-11(8-20-7-10)16(17,18)19/h2-3,6-8H,4-5H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503867 (CHEMBL4447011) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O/c1-9-12(2-3-14-13(9)4-5-21-15(14)22)10-6-11(8-20-7-10)16(17,18)19/h2-3,6-8H,4-5H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503852 (CHEMBL4470303) Show SMILES Brc1cccc2C(=O)NCCc12 Show InChI InChI=1S/C9H8BrNO/c10-8-3-1-2-7-6(8)4-5-11-9(7)12/h1-3H,4-5H2,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503852 (CHEMBL4470303) Show SMILES Brc1cccc2C(=O)NCCc12 Show InChI InChI=1S/C9H8BrNO/c10-8-3-1-2-7-6(8)4-5-11-9(7)12/h1-3H,4-5H2,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C18H16N2O/c1-11-14(3-4-16-15(11)7-9-20-18(16)21)12-2-5-17-13(10-12)6-8-19-17/h2-6,8,10,19H,7,9H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C18H16N2O/c1-11-14(3-4-16-15(11)7-9-20-18(16)21)12-2-5-17-13(10-12)6-8-19-17/h2-6,8,10,19H,7,9H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C17H15NO2/c1-11(19)12-3-2-4-13(9-12)14-5-6-16-15(10-14)7-8-18-17(16)20/h2-6,9-10H,7-8H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C17H15NO2/c1-11(19)12-3-2-4-13(9-12)14-5-6-16-15(10-14)7-8-18-17(16)20/h2-6,9-10H,7-8H2,1H3,(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair

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