Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with all data for entry = 50007072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50014619 (CHEMBL3184840) Show SMILES CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C69H108N22O16S/c1-39(2)32-47(85-57(96)43(17-9-26-76-68(71)72)82-63(102)52-20-12-29-90(52)65(104)45(18-10-27-77-69(73)74)83-58(97)44-22-23-54(93)80-44)59(98)88-50(37-92)61(100)86-48(34-41-35-75-38-79-41)60(99)81-42(16-7-8-25-70)56(95)78-36-55(94)89-28-11-19-51(89)62(101)84-46(24-31-108-3)66(105)91-30-13-21-53(91)64(103)87-49(67(106)107)33-40-14-5-4-6-15-40/h4-6,14-15,35,38-39,42-53,92H,7-13,16-34,36-37,70H2,1-3H3,(H,75,79)(H,78,95)(H,80,93)(H,81,99)(H,82,102)(H,83,97)(H,84,101)(H,85,96)(H,86,100)(H,87,103)(H,88,98)(H,106,107)(H4,71,72,76)(H4,73,74,77)/t42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0470	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506018 (CHEMBL4435973) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r,wD:3.35,(4.31,-6.81,;5.64,-6.04,;6.98,-6.81,;8.31,-6.04,;9.65,-6.8,;10.98,-6.03,;10.98,-4.49,;12.32,-6.8,;12.33,-8.35,;13.66,-9.12,;14.99,-8.34,;14.99,-6.8,;13.66,-6.03,;16.32,-6.03,;16.32,-4.49,;17.66,-6.8,;16.31,-9.12,;17.65,-8.34,;18.41,-6.99,;18.98,-9.11,;18.99,-10.66,;17.65,-11.43,;16.31,-10.66,;14.98,-11.43,;13.58,-10.81,;12.55,-11.95,;11.01,-11.95,;10.24,-13.27,;11.01,-14.61,;12.55,-14.61,;13.31,-13.28,;14.82,-12.96,;8.31,-4.5,;9.64,-3.73,;9.64,-2.19,;8.3,-1.42,;6.97,-2.2,;6.97,-3.74,)| Show InChI InChI=1S/C31H26ClN3O3/c1-2-9-25(19-10-4-3-5-11-19)35-30(36)20-16-17-21(23(18-20)31(37)38)28-22(12-8-13-24(28)32)29-33-26-14-6-7-15-27(26)34-29/h3-8,10-18,25H,2,9H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506017 (CHEMBL4547328) Show SMILES COc1ccc(NC(=O)c2ccc(Cl)cc2-c2ccc(cc2C(O)=O)C(=O)N[C@H](CO)c2ccccc2)cc1F |r| Show InChI InChI=1S/C30H24ClFN2O6/c1-40-27-12-9-20(15-25(27)32)33-29(37)22-11-8-19(31)14-23(22)21-10-7-18(13-24(21)30(38)39)28(36)34-26(16-35)17-5-3-2-4-6-17/h2-15,26,35H,16H2,1H3,(H,33,37)(H,34,36)(H,38,39)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Rattus norvegicus)	BDBM50506018 (CHEMBL4435973) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r,wD:3.35,(4.31,-6.81,;5.64,-6.04,;6.98,-6.81,;8.31,-6.04,;9.65,-6.8,;10.98,-6.03,;10.98,-4.49,;12.32,-6.8,;12.33,-8.35,;13.66,-9.12,;14.99,-8.34,;14.99,-6.8,;13.66,-6.03,;16.32,-6.03,;16.32,-4.49,;17.66,-6.8,;16.31,-9.12,;17.65,-8.34,;18.41,-6.99,;18.98,-9.11,;18.99,-10.66,;17.65,-11.43,;16.31,-10.66,;14.98,-11.43,;13.58,-10.81,;12.55,-11.95,;11.01,-11.95,;10.24,-13.27,;11.01,-14.61,;12.55,-14.61,;13.31,-13.28,;14.82,-12.96,;8.31,-4.5,;9.64,-3.73,;9.64,-2.19,;8.3,-1.42,;6.97,-2.2,;6.97,-3.74,)| Show InChI InChI=1S/C31H26ClN3O3/c1-2-9-25(19-10-4-3-5-11-19)35-30(36)20-16-17-21(23(18-20)31(37)38)28-22(12-8-13-24(28)32)29-33-26-14-6-7-15-27(26)34-29/h3-8,10-18,25H,2,9H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at rat APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by HT...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Rattus norvegicus)	BDBM50506019 (CHEMBL4473347) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2cc(OC)ccc2[nH]1)c1ccccc1 |r,wD:3.37,(50.15,-45.98,;51.48,-45.21,;52.81,-45.98,;54.15,-45.21,;55.49,-45.97,;56.82,-45.2,;56.82,-43.66,;58.16,-45.97,;58.16,-47.52,;59.5,-48.28,;60.83,-47.51,;60.83,-45.97,;59.49,-45.2,;62.16,-45.2,;62.16,-43.66,;63.49,-45.97,;62.15,-48.28,;63.48,-47.51,;64.24,-46.17,;64.82,-48.28,;64.82,-49.83,;63.48,-50.6,;62.15,-49.83,;60.82,-50.6,;60.66,-52.13,;59.15,-52.45,;58.38,-53.78,;56.85,-53.78,;56.09,-55.11,;54.55,-55.11,;56.07,-52.44,;56.85,-51.12,;58.39,-51.12,;59.42,-49.98,;54.15,-43.67,;55.48,-42.9,;55.48,-41.36,;54.14,-40.59,;52.8,-41.37,;52.81,-42.9,)| Show InChI InChI=1S/C32H28ClN3O4/c1-3-8-26(19-9-5-4-6-10-19)36-31(37)20-13-15-22(24(17-20)32(38)39)29-23(11-7-12-25(29)33)30-34-27-16-14-21(40-2)18-28(27)35-30/h4-7,9-18,26H,3,8H2,1-2H3,(H,34,35)(H,36,37)(H,38,39)/t26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at rat APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by HT...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Rattus norvegicus)	BDBM50014619 (CHEMBL3184840) Show SMILES CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C69H108N22O16S/c1-39(2)32-47(85-57(96)43(17-9-26-76-68(71)72)82-63(102)52-20-12-29-90(52)65(104)45(18-10-27-77-69(73)74)83-58(97)44-22-23-54(93)80-44)59(98)88-50(37-92)61(100)86-48(34-41-35-75-38-79-41)60(99)81-42(16-7-8-25-70)56(95)78-36-55(94)89-28-11-19-51(89)62(101)84-46(24-31-108-3)66(105)91-30-13-21-53(91)64(103)87-49(67(106)107)33-40-14-5-4-6-15-40/h4-6,14-15,35,38-39,42-53,92H,7-13,16-34,36-37,70H2,1-3H3,(H,75,79)(H,78,95)(H,80,93)(H,81,99)(H,82,102)(H,83,97)(H,84,101)(H,85,96)(H,86,100)(H,87,103)(H,88,98)(H,106,107)(H4,71,72,76)(H4,73,74,77)/t42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0620	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at rat APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by HT...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506019 (CHEMBL4473347) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2cc(OC)ccc2[nH]1)c1ccccc1 |r,wD:3.37,(50.15,-45.98,;51.48,-45.21,;52.81,-45.98,;54.15,-45.21,;55.49,-45.97,;56.82,-45.2,;56.82,-43.66,;58.16,-45.97,;58.16,-47.52,;59.5,-48.28,;60.83,-47.51,;60.83,-45.97,;59.49,-45.2,;62.16,-45.2,;62.16,-43.66,;63.49,-45.97,;62.15,-48.28,;63.48,-47.51,;64.24,-46.17,;64.82,-48.28,;64.82,-49.83,;63.48,-50.6,;62.15,-49.83,;60.82,-50.6,;60.66,-52.13,;59.15,-52.45,;58.38,-53.78,;56.85,-53.78,;56.09,-55.11,;54.55,-55.11,;56.07,-52.44,;56.85,-51.12,;58.39,-51.12,;59.42,-49.98,;54.15,-43.67,;55.48,-42.9,;55.48,-41.36,;54.14,-40.59,;52.8,-41.37,;52.81,-42.9,)| Show InChI InChI=1S/C32H28ClN3O4/c1-3-8-26(19-9-5-4-6-10-19)36-31(37)20-13-15-22(24(17-20)32(38)39)29-23(11-7-12-25(29)33)30-34-27-16-14-21(40-2)18-28(27)35-30/h4-7,9-18,26H,3,8H2,1-2H3,(H,34,35)(H,36,37)(H,38,39)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0620	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506020 (CHEMBL4450702) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(C)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r,wD:3.35,(52.74,-6.81,;54.08,-6.04,;55.41,-6.81,;56.75,-6.04,;58.09,-6.8,;59.42,-6.03,;59.42,-4.49,;60.76,-6.8,;60.76,-8.35,;62.09,-9.11,;63.42,-8.34,;63.42,-6.8,;62.09,-6.03,;64.76,-6.03,;64.76,-4.49,;66.09,-6.8,;64.75,-9.11,;66.08,-8.34,;66.84,-6.99,;67.42,-9.11,;67.42,-10.66,;66.08,-11.43,;64.75,-10.66,;63.41,-11.43,;62.01,-10.81,;60.99,-11.95,;59.45,-11.95,;58.67,-13.27,;59.45,-14.61,;60.98,-14.61,;61.75,-13.28,;63.26,-12.96,;56.75,-4.5,;58.08,-3.73,;58.08,-2.19,;56.74,-1.42,;55.4,-2.2,;55.41,-3.74,)| Show InChI InChI=1S/C32H29N3O3/c1-3-10-26(21-12-5-4-6-13-21)35-31(36)22-17-18-23(25(19-22)32(37)38)29-20(2)11-9-14-24(29)30-33-27-15-7-8-16-28(27)34-30/h4-9,11-19,26H,3,10H2,1-2H3,(H,33,34)(H,35,36)(H,37,38)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.180	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506018 (CHEMBL4435973) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r,wD:3.35,(4.31,-6.81,;5.64,-6.04,;6.98,-6.81,;8.31,-6.04,;9.65,-6.8,;10.98,-6.03,;10.98,-4.49,;12.32,-6.8,;12.33,-8.35,;13.66,-9.12,;14.99,-8.34,;14.99,-6.8,;13.66,-6.03,;16.32,-6.03,;16.32,-4.49,;17.66,-6.8,;16.31,-9.12,;17.65,-8.34,;18.41,-6.99,;18.98,-9.11,;18.99,-10.66,;17.65,-11.43,;16.31,-10.66,;14.98,-11.43,;13.58,-10.81,;12.55,-11.95,;11.01,-11.95,;10.24,-13.27,;11.01,-14.61,;12.55,-14.61,;13.31,-13.28,;14.82,-12.96,;8.31,-4.5,;9.64,-3.73,;9.64,-2.19,;8.3,-1.42,;6.97,-2.2,;6.97,-3.74,)| Show InChI InChI=1S/C31H26ClN3O3/c1-2-9-25(19-10-4-3-5-11-19)35-30(36)20-16-17-21(23(18-20)31(37)38)28-22(12-8-13-24(28)32)29-33-26-14-6-7-15-27(26)34-29/h3-8,10-18,25H,2,9H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0930	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506021 (CHEMBL4526882) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1ccc(Cl)cc1-c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C31H26ClN3O3/c1-2-8-26(19-9-4-3-5-10-19)35-30(36)20-13-15-23(25(17-20)31(37)38)22-16-14-21(32)18-24(22)29-33-27-11-6-7-12-28(27)34-29/h3-7,9-18,26H,2,8H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506022 (CHEMBL4561041) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cccc(Cl)c1-c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C31H26ClN3O3/c1-2-9-25(19-10-4-3-5-11-19)35-30(36)20-16-17-21(23(18-20)31(37)38)22-12-8-13-24(32)28(22)29-33-26-14-6-7-15-27(26)34-29/h3-8,10-18,25H,2,9H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506023 (CHEMBL4525712) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2ccccc2o1)c1ccccc1 |r| Show InChI InChI=1S/C31H25ClN2O4/c1-2-8-26(19-9-4-3-5-10-19)33-29(35)20-13-15-22(25(17-20)31(36)37)24-18-21(32)14-16-23(24)30-34-27-11-6-7-12-28(27)38-30/h3-7,9-18,26H,2,8H2,1H3,(H,33,35)(H,36,37)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506024 (CHEMBL4461195) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2ccncc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C30H25ClN4O3/c1-2-6-25(18-7-4-3-5-8-18)35-29(36)19-9-11-21(24(15-19)30(37)38)23-16-20(31)10-12-22(23)28-33-26-13-14-32-17-27(26)34-28/h3-5,7-17,25H,2,6H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506025 (CHEMBL4454971) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2cc(C)ccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C32H28ClN3O3/c1-3-7-27(20-8-5-4-6-9-20)36-31(37)21-11-13-23(26(17-21)32(38)39)25-18-22(33)12-14-24(25)30-34-28-15-10-19(2)16-29(28)35-30/h4-6,8-18,27H,3,7H2,1-2H3,(H,34,35)(H,36,37)(H,38,39)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506026 (CHEMBL4437206) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C31H26ClN3O3/c1-2-8-26(19-9-4-3-5-10-19)35-30(36)20-13-15-22(25(17-20)31(37)38)24-18-21(32)14-16-23(24)29-33-27-11-6-7-12-28(27)34-29/h3-7,9-18,26H,2,8H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506027 (CHEMBL4587131) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1C(=O)Nc1ccc(OC)c(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C32H28ClFN2O5/c1-3-7-28(19-8-5-4-6-9-19)36-30(37)20-10-13-23(26(16-20)32(39)40)25-17-21(33)11-14-24(25)31(38)35-22-12-15-29(41-2)27(34)18-22/h4-6,8-18,28H,3,7H2,1-2H3,(H,35,38)(H,36,37)(H,39,40)/t28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.330	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506028 (CHEMBL4444303) Show SMILES COC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1C(=O)Nc1ccc(OC)c(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C31H26ClFN2O6/c1-40-17-27(18-6-4-3-5-7-18)35-29(36)19-8-11-22(25(14-19)31(38)39)24-15-20(32)9-12-23(24)30(37)34-21-10-13-28(41-2)26(33)16-21/h3-16,27H,17H2,1-2H3,(H,34,37)(H,35,36)(H,38,39)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506029 (CHEMBL4441946) Show SMILES COc1ccc(NC(=O)c2ccc(Cl)cc2-c2ccc(cc2C(O)=O)C(=O)Nc2ccc3CCCc3c2)cc1F Show InChI InChI=1S/C31H24ClFN2O5/c1-40-28-12-9-22(16-27(28)33)35-30(37)24-11-7-20(32)15-25(24)23-10-6-19(14-26(23)31(38)39)29(36)34-21-8-5-17-3-2-4-18(17)13-21/h5-16H,2-4H2,1H3,(H,34,36)(H,35,37)(H,38,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506030 (CHEMBL4565753) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1ccccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C31H27N3O3/c1-2-10-26(20-11-4-3-5-12-20)34-30(35)21-17-18-23(25(19-21)31(36)37)22-13-6-7-14-24(22)29-32-27-15-8-9-16-28(27)33-29/h3-9,11-19,26H,2,10H2,1H3,(H,32,33)(H,34,35)(H,36,37)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506031 (CHEMBL4562873) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2cc(Cl)ccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C31H25Cl2N3O3/c1-2-6-26(18-7-4-3-5-8-18)36-30(37)19-9-12-22(25(15-19)31(38)39)24-16-20(32)10-13-23(24)29-34-27-14-11-21(33)17-28(27)35-29/h3-5,7-17,26H,2,6H2,1H3,(H,34,35)(H,36,37)(H,38,39)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.310	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506018 (CHEMBL4435973) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r,wD:3.35,(4.31,-6.81,;5.64,-6.04,;6.98,-6.81,;8.31,-6.04,;9.65,-6.8,;10.98,-6.03,;10.98,-4.49,;12.32,-6.8,;12.33,-8.35,;13.66,-9.12,;14.99,-8.34,;14.99,-6.8,;13.66,-6.03,;16.32,-6.03,;16.32,-4.49,;17.66,-6.8,;16.31,-9.12,;17.65,-8.34,;18.41,-6.99,;18.98,-9.11,;18.99,-10.66,;17.65,-11.43,;16.31,-10.66,;14.98,-11.43,;13.58,-10.81,;12.55,-11.95,;11.01,-11.95,;10.24,-13.27,;11.01,-14.61,;12.55,-14.61,;13.31,-13.28,;14.82,-12.96,;8.31,-4.5,;9.64,-3.73,;9.64,-2.19,;8.3,-1.42,;6.97,-2.2,;6.97,-3.74,)| Show InChI InChI=1S/C31H26ClN3O3/c1-2-9-25(19-10-4-3-5-11-19)35-30(36)20-16-17-21(23(18-20)31(37)38)28-22(12-8-13-24(28)32)29-33-26-14-6-7-15-27(26)34-29/h3-8,10-18,25H,2,9H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506032 (CHEMBL4578949) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(OC)ccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C32H29N3O4/c1-3-9-27(20-10-5-4-6-11-20)35-31(36)21-14-16-23(26(18-21)32(37)38)25-19-22(39-2)15-17-24(25)30-33-28-12-7-8-13-29(28)34-30/h4-8,10-19,27H,3,9H2,1-2H3,(H,33,34)(H,35,36)(H,37,38)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506033 (CHEMBL4473653) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(F)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r,wD:3.35,(27.17,-6.87,;28.49,-6.1,;29.83,-6.87,;31.16,-6.1,;32.5,-6.86,;33.84,-6.1,;33.83,-4.55,;35.17,-6.86,;35.18,-8.41,;36.51,-9.18,;37.84,-8.4,;37.84,-6.86,;36.51,-6.09,;39.17,-6.09,;39.17,-4.55,;40.51,-6.86,;39.17,-9.18,;40.5,-8.4,;41.25,-7.06,;41.83,-9.17,;41.84,-10.72,;40.5,-11.49,;39.16,-10.72,;37.84,-11.49,;36.43,-10.87,;35.4,-12.01,;33.87,-12.01,;33.09,-13.33,;33.86,-14.67,;35.4,-14.67,;36.16,-13.34,;37.67,-13.03,;31.16,-4.56,;32.5,-3.79,;32.49,-2.25,;31.16,-1.48,;29.82,-2.26,;29.83,-3.8,)| Show InChI InChI=1S/C31H26FN3O3/c1-2-9-25(19-10-4-3-5-11-19)35-30(36)20-16-17-21(23(18-20)31(37)38)28-22(12-8-13-24(28)32)29-33-26-14-6-7-15-27(26)34-29/h3-8,10-18,25H,2,9H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.510	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506034 (CHEMBL4444538) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(C)ccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C32H29N3O3/c1-3-9-27(21-10-5-4-6-11-21)35-31(36)22-15-17-23(26(19-22)32(37)38)25-18-20(2)14-16-24(25)30-33-28-12-7-8-13-29(28)34-30/h4-8,10-19,27H,3,9H2,1-2H3,(H,33,34)(H,35,36)(H,37,38)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506035 (CHEMBL4437702) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2cccc(C)c2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C32H28ClN3O3/c1-3-8-27(20-10-5-4-6-11-20)35-31(37)21-13-15-23(26(17-21)32(38)39)25-18-22(33)14-16-24(25)30-34-28-12-7-9-19(2)29(28)36-30/h4-7,9-18,27H,3,8H2,1-2H3,(H,34,36)(H,35,37)(H,38,39)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506036 (CHEMBL4443604) Show SMILES COC[C@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1C(=O)Nc1ccc(OC)c(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C31H26ClFN2O6/c1-40-17-27(18-6-4-3-5-7-18)35-29(36)19-8-11-22(25(14-19)31(38)39)24-15-20(32)9-12-23(24)30(37)34-21-10-13-28(41-2)26(33)16-21/h3-16,27H,17H2,1-2H3,(H,34,37)(H,35,36)(H,38,39)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Rattus norvegicus)	BDBM50506018 (CHEMBL4435973) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r,wD:3.35,(4.31,-6.81,;5.64,-6.04,;6.98,-6.81,;8.31,-6.04,;9.65,-6.8,;10.98,-6.03,;10.98,-4.49,;12.32,-6.8,;12.33,-8.35,;13.66,-9.12,;14.99,-8.34,;14.99,-6.8,;13.66,-6.03,;16.32,-6.03,;16.32,-4.49,;17.66,-6.8,;16.31,-9.12,;17.65,-8.34,;18.41,-6.99,;18.98,-9.11,;18.99,-10.66,;17.65,-11.43,;16.31,-10.66,;14.98,-11.43,;13.58,-10.81,;12.55,-11.95,;11.01,-11.95,;10.24,-13.27,;11.01,-14.61,;12.55,-14.61,;13.31,-13.28,;14.82,-12.96,;8.31,-4.5,;9.64,-3.73,;9.64,-2.19,;8.3,-1.42,;6.97,-2.2,;6.97,-3.74,)| Show InChI InChI=1S/C31H26ClN3O3/c1-2-9-25(19-10-4-3-5-11-19)35-30(36)20-16-17-21(23(18-20)31(37)38)28-22(12-8-13-24(28)32)29-33-26-14-6-7-15-27(26)34-29/h3-8,10-18,25H,2,9H2,1H3,(H,33,34)(H,35,36)(H,37,38)/t25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at rat APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by HT...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506037 (CHEMBL4518406) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2cc(OC)ccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C32H28ClN3O4/c1-3-7-27(19-8-5-4-6-9-19)36-31(37)20-10-13-23(26(16-20)32(38)39)25-17-21(33)11-14-24(25)30-34-28-15-12-22(40-2)18-29(28)35-30/h4-6,8-18,27H,3,7H2,1-2H3,(H,34,35)(H,36,37)(H,38,39)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0830	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50506016 (CHEMBL4569052) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1ncc([nH]1)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C33H28ClN3O3/c1-2-9-29(21-10-5-3-6-11-21)37-32(38)23-14-16-25(28(18-23)33(39)40)27-19-24(34)15-17-26(27)31-35-20-30(36-31)22-12-7-4-8-13-22/h3-8,10-20,29H,2,9H2,1H3,(H,35,36)(H,37,38)(H,39,40)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513 BindingDB Entry DOI: 10.7270/Q2RN3C5X
					More data for this Ligand-Target Pair