Compile Data Set for Download or QSAR

Found 88 hits Enz. Inhib. hit(s) with all data for entry = 50007211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507415 (CHEMBL4451025) Show SMILES OC(=O)CNC(=O)c1c(O)c2cc(OC(F)(F)F)cc3OC(Cn(c23)c1=O)c1ccc(cc1)C#N Show InChI InChI=1S/C22H14F3N3O7/c23-22(24,25)35-12-5-13-18-14(6-12)34-15(11-3-1-10(7-26)2-4-11)9-28(18)21(33)17(19(13)31)20(32)27-8-16(29)30/h1-6,15,31H,8-9H2,(H,27,32)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507415 (CHEMBL4451025) Show SMILES OC(=O)CNC(=O)c1c(O)c2cc(OC(F)(F)F)cc3OC(Cn(c23)c1=O)c1ccc(cc1)C#N Show InChI InChI=1S/C22H14F3N3O7/c23-22(24,25)35-12-5-13-18-14(6-12)34-15(11-3-1-10(7-26)2-4-11)9-28(18)21(33)17(19(13)31)20(32)27-8-16(29)30/h1-6,15,31H,8-9H2,(H,27,32)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507419 (CHEMBL4462855) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C17H15ClN2O6/c18-10-3-1-9(2-4-10)6-20-12-8-26-7-11(12)15(23)14(17(20)25)16(24)19-5-13(21)22/h1-4,23H,5-8H2,(H,19,24)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507404 (CHEMBL4443606) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3OCC(c4cncs4)n(c23)c1=O Show InChI InChI=1S/C17H13N3O6S/c21-12(22)5-19-16(24)13-15(23)8-2-1-3-10-14(8)20(17(13)25)9(6-26-10)11-4-18-7-27-11/h1-4,7,9,23H,5-6H2,(H,19,24)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507404 (CHEMBL4443606) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3OCC(c4cncs4)n(c23)c1=O Show InChI InChI=1S/C17H13N3O6S/c21-12(22)5-19-16(24)13-15(23)8-2-1-3-10-14(8)20(17(13)25)9(6-26-10)11-4-18-7-27-11/h1-4,7,9,23H,5-6H2,(H,19,24)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507420 (CHEMBL4529447) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(F)cc2F)c1=O Show InChI InChI=1S/C17H14F2N2O6/c18-9-2-1-8(11(19)3-9)5-21-12-7-27-6-10(12)15(24)14(17(21)26)16(25)20-4-13(22)23/h1-3,24H,4-7H2,(H,20,25)(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507406 (CHEMBL4452218) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3NC(Cn(c23)c1=O)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C20H15F3N4O5/c21-20(22,23)13-5-4-9(6-24-13)12-8-27-16-10(2-1-3-11(16)26-12)17(30)15(19(27)32)18(31)25-7-14(28)29/h1-6,12,26,30H,7-8H2,(H,25,31)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507419 (CHEMBL4462855) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C17H15ClN2O6/c18-10-3-1-9(2-4-10)6-20-12-8-26-7-11(12)15(23)14(17(20)25)16(24)19-5-13(21)22/h1-4,23H,5-8H2,(H,19,24)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507408 (CHEMBL4561977) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(OC(F)(F)F)cc2)c1=O Show InChI InChI=1S/C18H15F3N2O7/c19-18(20,21)30-10-3-1-9(2-4-10)6-23-12-8-29-7-11(12)15(26)14(17(23)28)16(27)22-5-13(24)25/h1-4,26H,5-8H2,(H,22,27)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507407 (CHEMBL4590677) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(s2)C(F)(F)F)c1=O Show InChI InChI=1S/C15H12F3N3O6S/c16-15(17,18)14-20-1-6(28-14)3-21-8-5-27-4-7(8)11(24)10(13(21)26)12(25)19-2-9(22)23/h1,24H,2-5H2,(H,19,25)(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507420 (CHEMBL4529447) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(F)cc2F)c1=O Show InChI InChI=1S/C17H14F2N2O6/c18-9-2-1-8(11(19)3-9)5-21-12-7-27-6-10(12)15(24)14(17(21)26)16(25)20-4-13(22)23/h1-3,24H,4-7H2,(H,20,25)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507408 (CHEMBL4561977) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(OC(F)(F)F)cc2)c1=O Show InChI InChI=1S/C18H15F3N2O7/c19-18(20,21)30-10-3-1-9(2-4-10)6-23-12-8-29-7-11(12)15(26)14(17(23)28)16(27)22-5-13(24)25/h1-4,26H,5-8H2,(H,22,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507421 (CHEMBL4462741) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cc(F)c(F)cc2F)c1=O Show InChI InChI=1S/C17H13F3N2O6/c18-9-2-11(20)10(19)1-7(9)4-22-12-6-28-5-8(12)15(25)14(17(22)27)16(26)21-3-13(23)24/h1-2,25H,3-6H2,(H,21,26)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507409 (CHEMBL4476576) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccn(n2)-c2ccccc2)c1=O Show InChI InChI=1S/C20H18N4O6/c25-16(26)8-21-19(28)17-18(27)14-10-30-11-15(14)23(20(17)29)9-12-6-7-24(22-12)13-4-2-1-3-5-13/h1-7,27H,8-11H2,(H,21,28)(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507413 (CHEMBL4564341) Show SMILES OC(=O)CNC(=O)c1c(O)c2ccc(Cl)cc2n(Cc2ccc(cc2)C(F)(F)F)c1=O Show InChI InChI=1S/C20H14ClF3N2O5/c21-12-5-6-13-14(7-12)26(9-10-1-3-11(4-2-10)20(22,23)24)19(31)16(17(13)29)18(30)25-8-15(27)28/h1-7,29H,8-9H2,(H,25,30)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50318681 (CHEMBL4162309) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCCc2n(Cc2nc3ccccc3s2)c1=O Show InChI InChI=1S/C19H17N3O6S/c23-15(24)7-20-18(26)16-17(25)10-9-28-6-5-12(10)22(19(16)27)8-14-21-11-3-1-2-4-13(11)29-14/h1-4,25H,5-9H2,(H,20,26)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507425 (CHEMBL4458708) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(nc2)C(F)(F)F)c1=O Show InChI InChI=1S/C17H14F3N3O6/c18-17(19,20)11-2-1-8(3-21-11)5-23-10-7-29-6-9(10)14(26)13(16(23)28)15(27)22-4-12(24)25/h1-3,26H,4-7H2,(H,22,27)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507405 (CHEMBL4577928) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(cc2)C(F)(F)F)c1=O Show InChI InChI=1S/C18H15F3N2O6/c19-18(20,21)10-3-1-9(2-4-10)6-23-12-8-29-7-11(12)15(26)14(17(23)28)16(27)22-5-13(24)25/h1-4,26H,5-8H2,(H,22,27)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507424 (CHEMBL4452138) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2nc(cs2)C(F)(F)F)c1=O Show InChI InChI=1S/C15H12F3N3O6S/c16-15(17,18)8-5-28-9(20-8)2-21-7-4-27-3-6(7)12(24)11(14(21)26)13(25)19-1-10(22)23/h5,24H,1-4H2,(H,19,25)(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507409 (CHEMBL4476576) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccn(n2)-c2ccccc2)c1=O Show InChI InChI=1S/C20H18N4O6/c25-16(26)8-21-19(28)17-18(27)14-10-30-11-15(14)23(20(17)29)9-12-6-7-24(22-12)13-4-2-1-3-5-13/h1-7,27H,8-11H2,(H,21,28)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507412 (CHEMBL4454844) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3SC(Cn(c23)c1=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O5S/c22-21(23,24)11-6-4-10(5-7-11)14-9-26-17-12(2-1-3-13(17)32-14)18(29)16(20(26)31)19(30)25-8-15(27)28/h1-7,14,29H,8-9H2,(H,25,30)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507407 (CHEMBL4590677) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(s2)C(F)(F)F)c1=O Show InChI InChI=1S/C15H12F3N3O6S/c16-15(17,18)14-20-1-6(28-14)3-21-8-5-27-4-7(8)11(24)10(13(21)26)12(25)19-2-9(22)23/h1,24H,2-5H2,(H,19,25)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507404 (CHEMBL4443606) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3OCC(c4cncs4)n(c23)c1=O Show InChI InChI=1S/C17H13N3O6S/c21-12(22)5-19-16(24)13-15(23)8-2-1-3-10-14(8)20(17(13)25)9(6-26-10)11-4-18-7-27-11/h1-4,7,9,23H,5-6H2,(H,19,24)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507411 (CHEMBL4474474) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2nc3ccccc3o2)c1=O Show InChI InChI=1S/C18H15N3O7/c22-14(23)5-19-17(25)15-16(24)9-7-27-8-11(9)21(18(15)26)6-13-20-10-3-1-2-4-12(10)28-13/h1-4,24H,5-8H2,(H,19,25)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507404 (CHEMBL4443606) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3OCC(c4cncs4)n(c23)c1=O Show InChI InChI=1S/C17H13N3O6S/c21-12(22)5-19-16(24)13-15(23)8-2-1-3-10-14(8)20(17(13)25)9(6-26-10)11-4-18-7-27-11/h1-4,7,9,23H,5-6H2,(H,19,24)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507424 (CHEMBL4452138) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2nc(cs2)C(F)(F)F)c1=O Show InChI InChI=1S/C15H12F3N3O6S/c16-15(17,18)8-5-28-9(20-8)2-21-7-4-27-3-6(7)12(24)11(14(21)26)13(25)19-1-10(22)23/h5,24H,1-4H2,(H,19,25)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507421 (CHEMBL4462741) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cc(F)c(F)cc2F)c1=O Show InChI InChI=1S/C17H13F3N2O6/c18-9-2-11(20)10(19)1-7(9)4-22-12-6-28-5-8(12)15(25)14(17(22)27)16(26)21-3-13(23)24/h1-2,25H,3-6H2,(H,21,26)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507413 (CHEMBL4564341) Show SMILES OC(=O)CNC(=O)c1c(O)c2ccc(Cl)cc2n(Cc2ccc(cc2)C(F)(F)F)c1=O Show InChI InChI=1S/C20H14ClF3N2O5/c21-12-5-6-13-14(7-12)26(9-10-1-3-11(4-2-10)20(22,23)24)19(31)16(17(13)29)18(30)25-8-15(27)28/h1-7,29H,8-9H2,(H,25,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507429 (CHEMBL4552680) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3OCC(c4ccc(nc4)C(F)(F)F)n(c23)c1=O Show InChI InChI=1S/C20H14F3N3O6/c21-20(22,23)13-5-4-9(6-24-13)11-8-32-12-3-1-2-10-16(12)26(11)19(31)15(17(10)29)18(30)25-7-14(27)28/h1-6,11,29H,7-8H2,(H,25,30)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507405 (CHEMBL4577928) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(cc2)C(F)(F)F)c1=O Show InChI InChI=1S/C18H15F3N2O6/c19-18(20,21)10-3-1-9(2-4-10)6-23-12-8-29-7-11(12)15(26)14(17(23)28)16(27)22-5-13(24)25/h1-4,26H,5-8H2,(H,22,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507428 (CHEMBL4567141) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(cn2)C(F)(F)F)c1=O Show InChI InChI=1S/C16H13F3N4O6/c17-16(18,19)10-2-20-7(1-21-10)4-23-9-6-29-5-8(9)13(26)12(15(23)28)14(27)22-3-11(24)25/h1-2,26H,3-6H2,(H,22,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507428 (CHEMBL4567141) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(cn2)C(F)(F)F)c1=O Show InChI InChI=1S/C16H13F3N4O6/c17-16(18,19)10-2-20-7(1-21-10)4-23-9-6-29-5-8(9)13(26)12(15(23)28)14(27)22-3-11(24)25/h1-2,26H,3-6H2,(H,22,27)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507411 (CHEMBL4474474) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2nc3ccccc3o2)c1=O Show InChI InChI=1S/C18H15N3O7/c22-14(23)5-19-17(25)15-16(24)9-7-27-8-11(9)21(18(15)26)6-13-20-10-3-1-2-4-12(10)28-13/h1-4,24H,5-8H2,(H,19,25)(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507415 (CHEMBL4451025) Show SMILES OC(=O)CNC(=O)c1c(O)c2cc(OC(F)(F)F)cc3OC(Cn(c23)c1=O)c1ccc(cc1)C#N Show InChI InChI=1S/C22H14F3N3O7/c23-22(24,25)35-12-5-13-18-14(6-12)34-15(11-3-1-10(7-26)2-4-11)9-28(18)21(33)17(19(13)31)20(32)27-8-16(29)30/h1-6,15,31H,8-9H2,(H,27,32)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507425 (CHEMBL4458708) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(nc2)C(F)(F)F)c1=O Show InChI InChI=1S/C17H14F3N3O6/c18-17(19,20)11-2-1-8(3-21-11)5-23-10-7-29-6-9(10)14(26)13(16(23)28)15(27)22-4-12(24)25/h1-3,26H,4-7H2,(H,22,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50318681 (CHEMBL4162309) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCCc2n(Cc2nc3ccccc3s2)c1=O Show InChI InChI=1S/C19H17N3O6S/c23-15(24)7-20-18(26)16-17(25)10-9-28-6-5-12(10)22(19(16)27)8-14-21-11-3-1-2-4-13(11)29-14/h1-4,25H,5-9H2,(H,20,26)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507406 (CHEMBL4452218) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3NC(Cn(c23)c1=O)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C20H15F3N4O5/c21-20(22,23)13-5-4-9(6-24-13)12-8-27-16-10(2-1-3-11(16)26-12)17(30)15(19(27)32)18(31)25-7-14(28)29/h1-6,12,26,30H,7-8H2,(H,25,31)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507408 (CHEMBL4561977) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(OC(F)(F)F)cc2)c1=O Show InChI InChI=1S/C18H15F3N2O7/c19-18(20,21)30-10-3-1-9(2-4-10)6-23-12-8-29-7-11(12)15(26)14(17(23)28)16(27)22-5-13(24)25/h1-4,26H,5-8H2,(H,22,27)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507418 (CHEMBL4471891) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCCc2n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C18H17ClN2O6/c19-11-3-1-10(2-4-11)8-21-13-5-6-27-9-12(13)16(24)15(18(21)26)17(25)20-7-14(22)23/h1-4,24H,5-9H2,(H,20,25)(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507409 (CHEMBL4476576) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccn(n2)-c2ccccc2)c1=O Show InChI InChI=1S/C20H18N4O6/c25-16(26)8-21-19(28)17-18(27)14-10-30-11-15(14)23(20(17)29)9-12-6-7-24(22-12)13-4-2-1-3-5-13/h1-7,27H,8-11H2,(H,21,28)(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507429 (CHEMBL4552680) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3OCC(c4ccc(nc4)C(F)(F)F)n(c23)c1=O Show InChI InChI=1S/C20H14F3N3O6/c21-20(22,23)13-5-4-9(6-24-13)11-8-32-12-3-1-2-10-16(12)26(11)19(31)15(17(10)29)18(30)25-7-14(27)28/h1-6,11,29H,7-8H2,(H,25,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507410 (CHEMBL4483401) Show SMILES CC(C)(O)c1ccc(Cn2c3COCc3c(O)c(C(=O)NCC(O)=O)c2=O)cc1 Show InChI InChI=1S/C20H22N2O7/c1-20(2,28)12-5-3-11(4-6-12)8-22-14-10-29-9-13(14)17(25)16(19(22)27)18(26)21-7-15(23)24/h3-6,25,28H,7-10H2,1-2H3,(H,21,26)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507427 (CHEMBL4573825) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCCc2n(Cc2ccc(cc2F)C#N)c1=O Show InChI InChI=1S/C19H16FN3O6/c20-13-5-10(6-21)1-2-11(13)8-23-14-3-4-29-9-12(14)17(26)16(19(23)28)18(27)22-7-15(24)25/h1-2,5,26H,3-4,7-9H2,(H,22,27)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507419 (CHEMBL4462855) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C17H15ClN2O6/c18-10-3-1-9(2-4-10)6-20-12-8-26-7-11(12)15(23)14(17(20)25)16(24)19-5-13(21)22/h1-4,23H,5-8H2,(H,19,24)(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507407 (CHEMBL4590677) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(s2)C(F)(F)F)c1=O Show InChI InChI=1S/C15H12F3N3O6S/c16-15(17,18)14-20-1-6(28-14)3-21-8-5-27-4-7(8)11(24)10(13(21)26)12(25)19-2-9(22)23/h1,24H,2-5H2,(H,19,25)(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507412 (CHEMBL4454844) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3SC(Cn(c23)c1=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O5S/c22-21(23,24)11-6-4-10(5-7-11)14-9-26-17-12(2-1-3-13(17)32-14)18(29)16(20(26)31)19(30)25-8-15(27)28/h1-7,14,29H,8-9H2,(H,25,30)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507411 (CHEMBL4474474) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2nc3ccccc3o2)c1=O Show InChI InChI=1S/C18H15N3O7/c22-14(23)5-19-17(25)15-16(24)9-7-27-8-11(9)21(18(15)26)6-13-20-10-3-1-2-4-12(10)28-13/h1-4,24H,5-8H2,(H,19,25)(H,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507406 (CHEMBL4452218) Show SMILES OC(=O)CNC(=O)c1c(O)c2cccc3NC(Cn(c23)c1=O)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C20H15F3N4O5/c21-20(22,23)13-5-4-9(6-24-13)12-8-27-16-10(2-1-3-11(16)26-12)17(30)15(19(27)32)18(31)25-7-14(28)29/h1-6,12,26,30H,7-8H2,(H,25,31)(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507421 (CHEMBL4462741) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cc(F)c(F)cc2F)c1=O Show InChI InChI=1S/C17H13F3N2O6/c18-9-2-11(20)10(19)1-7(9)4-22-12-6-28-5-8(12)15(25)14(17(22)27)16(26)21-3-13(23)24/h1-2,25H,3-6H2,(H,21,26)(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM50507426 (CHEMBL4461978) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCCc2n(Cc2ccc(nc2)C(F)(F)F)c1=O Show InChI InChI=1S/C18H16F3N3O6/c19-18(20,21)12-2-1-9(5-22-12)7-24-11-3-4-30-8-10(11)15(27)14(17(24)29)16(28)23-6-13(25)26/h1-2,5,27H,3-4,6-8H2,(H,23,28)(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274 BindingDB Entry DOI: 10.7270/Q2MG7SSH
					More data for this Ligand-Target Pair

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