Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510218![]() (CHEMBL4439603) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510219![]() (CHEMBL4439224) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510220![]() (CHEMBL4555970) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510221![]() (CHEMBL4555691) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510222![]() (CHEMBL4586326) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510223![]() (CHEMBL4444249) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510230![]() (CHEMBL4465346) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510225![]() (CHEMBL4450105) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510226![]() (CHEMBL4469129) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510227![]() (CHEMBL4445386) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510228![]() (CHEMBL4469234) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510229![]() (CHEMBL4472065) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioadenosine phosphorylase (Homo sapiens (Human)) | BDBM50510224![]() (CHEMBL4451807) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a |
Albert Einstein College of Medicine Curated by ChEMBL | Assay Description Binding affinity to recombinant human N-terminal TEV cleavage site-fused-His6-tagged MTAP expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL comp... | J Med Chem 62: 3286-3296 (2019) Article DOI: 10.1021/acs.jmedchem.8b01642 BindingDB Entry DOI: 10.7270/Q2JM2DXM | |||||||||||
More data for this Ligand-Target Pair |