Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM50512383 (CHEMBL137766) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.960 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of human MetAP2 | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM50147349 ((R)-3-(S)-Amino-2-hydroxy-5-phenyl-pentanoic acid ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of human MetAP2 | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM50147344 ((2S,3R)-3-Amino-4-cyclohexyl-2-hydroxy-N-{4-[3-(3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of human MetAP2 | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM50147357 ((R)-3-(S)-Amino-2-hydroxy-4-phenyl-N-{4-[3-((E)-3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 755 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of human MetAP2 | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting method | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting method | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM25737 (12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Competitive inhibition of soluble epoxide hydrolase (unknown origin) | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM50512380 (CHEMBL4565675) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Competitive inhibition of soluble epoxide hydrolase (unknown origin) | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232203 ((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting method | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM50512385 (CHEMBL4521296) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Competitive inhibition of soluble epoxide hydrolase (unknown origin) | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50512384 (CHEMBL1910917 | Phenyl-3'',4'',5''-Trimethoxycinna...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in CHO-K1 cell membranes after 60 mins by microbeta counting method | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232202 ((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232204 (3,4,5-Trimethoxycinnamic acid (TMCA)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 mins | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM50512381 (CHEMBL4521063) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Competitive inhibition of soluble epoxide hydrolase (unknown origin) | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM50512382 (CHEMBL4444323) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Competitive inhibition of soluble epoxide hydrolase (unknown origin) | Eur J Med Chem 173: 213-227 (2019) Article DOI: 10.1016/j.ejmech.2019.04.009 BindingDB Entry DOI: 10.7270/Q26M3B56 | |||||||||||
More data for this Ligand-Target Pair |