Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human OPM1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human MM.1S cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human RPMI8226 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human LR5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit OPM2 in human OPM1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human INA60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human MM.1R cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human KMS12PE cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-8 (Homo sapiens (Human)) | BDBM50099663![]() (CHEMBL3319482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of immunoproteasome subunit LMP7 in human DOX40 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | J Med Chem 63: 1841-1858 (2020) Article DOI: 10.1021/acs.jmedchem.9b01226 BindingDB Entry DOI: 10.7270/Q2QZ2F9Z | |||||||||||
More data for this Ligand-Target Pair |